June 2020
The IRB Review
A compilation of information, announcements, & updates for UK Institutional Review Board (IRB) members, research investigators, & others involved with human subject research.

Applying the UK Resumption of Research Phase Plan to Human Subject Research  

ORI has developed  Human Subjects Research FAQs  for applying UK’s Resumption of Research Phased Plan released by the Vice President for Research (VPR). The FAQs include a  Human Subjects Research Phases Table with examples of the type of study appropriate to resume with each phase.

Consolidated Guide for
Submitting and Conducting COVID-19 Human Research

This guidance combines questions and answers for newly initiated COVID-19 protocols or modifications to add COVID-19 objectives to existing research. Click to view guidance.

Revised "UK ORI Best Practice for Remote Informed Consent Guide" 

This guide outlines requirements and best practices for remote consent of subjects unable to travel to the research site and those isolated for infection control reasons. Additional guidance and tools are provided for FDA-regulated research which has the extra requirements for electronic records and signatures (FDA 21 CFR part 11). Click to view guidance.
IRB Members Dr. Jay Avasarala and
Dr. Avinash Bhakta featured in recent UKNOW articles

Dr. Jagannadha ‘Jay’ Avasarala and Maddison Higgins from the Kentucky Neuroscience Institute
UK Neurologist Believes MS Diagnosis Guidelines Need Updated
By  Hillary Smith | UK NOW   May 22, 2020
Dr. Jagannadha ‘Jay’ Avasarala, neurologist with the Kentucky Neuroscience Institute (KNI), recently published a study with others from the University of Kentucky’s Department of Neurology based on the fact that symptoms of MS can overlap with another disease known as neuromyelitis optica spectrum disorder (NMOSD).
Dr. Avinash Bhakta, colorectal cancer surgeon with the UK Markey Cancer Center and lead author.
UK Study Finds Many Colon Cancer Patients Not Receiving Standard of Care Therapy
By  Allison Perry| UK NOW  
May 26, 2020

Dr. Avinash Bhakta, colorectal cancer surgeon with the UK Markey Cancer Center and lead author on the study, says the study highlights the importance of the adherence to standard of care for these patients. 
UK Study Shows Opioid, Sedative and Antidepressant Use Pre-Surgery Leads to Worse Outcomes
By  Allison Perry| UK NOW  
June 8, 2020
“Most colorectal resections are elective in nature, so we want to focus on the use of opioids and sedatives and counsel patients on the need to decrease the use of these drugs before surgery,” Bhakta said. 
Upcoming ORI Office Hours
June 25, 2020
11 am - 12 pm
July 14, 2020
1 pm - 2 pm