March 2025

KDIGO has published the final report from its Controversies Conference on Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD): Progress and Knowledge Gaps Toward Personalizing Care, co-chaired by Markus Ketteler, MD (Germany), and Rosa Moysés, MD (Brazil). Published in the March issue of Kidney International, the report highlights the urgent need for a patient-centered approach to CKD-MBD management, outlines key knowledge gaps, and calls for further research.

“Our understanding of CKD-MBD has grown far beyond simply managing biochemical markers,” said Dr. Ketteler. “This report highlights the intricate relationship between bone health and cardiovascular disease in CKD patients and calls for a personalized care model that addresses the broader clinical picture. Managing CKD-MBD isn’t just about correcting lab values—it’s about preventing fractures, mitigating cardiovascular risks, and improving quality of life. It’s time to move away from rigid, one-size-fits-all frameworks and towards strategies that reflect the unique needs of each patient.”  

The report introduces a framework that categorizes CKD-MBD into CKD-associated osteoporosis, focusing on fracture prevention and bone health, and CKD-associated cardiovascular disease, addressing vascular calcification and cardiac complications. It calls for advanced imaging, novel biomarkers, and individualized phosphate and calcium management to balance bone and cardiovascular health. The report also emphasizes refining treatment targets for parathyroid hormone (PTH), vitamin D, and other mineral metabolism markers, while advocating for more inclusive clinical trials, particularly for post-transplant and pediatric populations. 



“One of the most powerful messages from this meeting is that CKD-MBD management must center on the patient, not just the disease,” said Dr. Moysés. “This report recognizes that factors like inflammation, uremic toxins, immune dysregulation, and gut health all influence CKD-MBD progression. We need strategies that go beyond surface-level treatment and address the root causes, while also considering the patient’s overall health, lifestyle, and preferences. By embracing a holistic, patient-centered approach, we can reduce fracture risk, slow cardiovascular disease progression, and ultimately improve survival and quality of life.” Read the full report.  

KDIGO has produced a new video series highlighting key takeaways from the KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD). The series is designed as a practical resource to ensure that the latest KDIGO recommendations are accessible and applicable in real-world clinical settings.

The videos feature insights from ADPKD Guideline Work Group Members Arlene Chapman, MD (United States), and Peter Harris, MD (United States), along with Guideline Co-Chair Vicente Torres, MD (United States). Together, they provide expert analysis of the latest evidence-based recommendations to help clinicians, patients, and caregivers navigate ADPKD care. They cover critical topics such as the classification and diagnosis of ADPKD, disease progression and management strategies, and treatment options, including both pharmacologic and non-pharmacologic approaches. The series also examines extrarenal manifestations of the disease, lifestyle considerations such as diet and exercise, and key issues related to reproductive health and pediatric care.

You can watch the video series and download the KDIGO 2025 ADPKD Guideline, Executive Summary, and Key Takeaways on the KDIGO ADPKD Guideline Website.

If you have an idea for a KDIGO Controversies Conference, you can now submit your topic for consideration via the link below. Submissions are reviewed by the KDIGO Executive Committee. Controversies Conferences are designed to bring together experts to discuss and debate nephrology-related issues that are not fully resolved. These conferences result in a peer-reviewed publication summarizing the controversies discussed and the conclusions of conference attendees.  Controversies Conferences do not necessarily lead to the development or revision of KDIGO Clinical Practice Guidelines. However, they can inform these processes. Submit your KDIGO Controversies Conference idea.

e-SPACE CRM 2025

Virtual Event

April 4-5, 2025, Multiple Time Zones

KDIGO, Radcliffe Cardiology, and the Translational Medicine Academy (TMA) invite you to e-SPACE Cardio-Renal-Metabolic (CRM) 2025, a global virtual event from April 4 to 5, 2025. This year's e-Space will bring together leading experts in cardiology, nephrology, and diabetology to explore the complex relationships among metabolic risk factors, diabetes, chronic kidney disease, and cardiovascular health.

The program will feature expert presentations, live panel discussions, and interactive "meet the expert" sessions designed to provide clinicians with practical, real-world insights. With a strong multidisciplinary approach, the program will balance global perspectives with regionally relevant insights, ensuring participants gain knowledge applicable to their clinical practice.

Following the success of e-SPACE CRM 2024, which gathered 60 faculty members and more than 2,000 healthcare professionals, e-SPACE 2025 will build on its mission to advance professional development and improve patient outcomes worldwide. The event is led by an esteemed international faculty and supported by TMA’s expertise in education delivery. It will also be submitted for EBAC® accreditation, offering participants the opportunity to earn continuing medical education credits. Registration is free and now open. To learn more and watch e-SPACE CRM 2024 on demand, visit e-SPACE CRM 2025.

30-Year Case Study: Implementing Global Guidelines for Data-Driven Diabetes Management in Hong Kong

KDIGO Summit Report

KDIGO recently published the first of two summit reports from the KDIGO Implementation Summit on Diabetes Management in CKD: From Primary to Collaborative Care in Lancet Regional Health – Western Pacific. The report summarizes discussions from the July 2023 summit in Hong Kong, co-chaired by Juliana Chan, MD (Hong Kong), and Philip Li, MD (Hong Kong). Experts in nephrology, endocrinology, and primary care gathered to address barriers to implementing guideline-based diabetes and CKD care, with a particular focus on strengthening primary care’s role in disease management.

This summit analyzed, and the report highlights, Hong Kong’s success in data-driven diabetes management through initiatives like the Hong Kong Diabetes Register, the Joint Asia Diabetes Evaluation Programme, and the Risk Assessment and Management Programme. These programs have significantly reduced diabetes-related complications and mortality by integrating structured risk assessment, digital health tools, and multidisciplinary collaboration. The report also explores strategies to improve communication between specialists and primary care providers, leverage digital innovations, and address gaps in care for young-onset diabetes, a growing population with a high risk of complications. The full report is available on the Lancet Regional Health – Western Pacific and KDIGO Hong Kong Implementation Summit websites.

KDIGO Webinar Series on Implementing Genetic Testing for CKD in the Real World Setting

On-Demand Webinar Series

The KDIGO Webinar Series on Implementing Genetic Testing for Chronic Kidney Disease (CKD) in the Real World Setting is now available for on-demand viewing. This four-part series brings together leading experts in nephrology and genetics, including Andrew Mallett, MD (Australia), Hila Rasouly, MD (United States), Ali Gharavi, MD (United States), Emilie Cornec-Le Gall, MD (France), Judy Savige, MD (Australia), Katalin Susztak, MD (United States), Nine V.A.M. Knoers, MD (The Netherlands), Matthew Sampson, MD (United States), and Ulla Schultheiss, MD (Germany).

The series explores essential topics, beginning with the foundational role of genetics in CKD management and the logistics of genetic testing. It then examines the utility of genetic testing in diagnosing conditions such as cystic kidney disease, glomerular disease, and APOL1-related kidney disease. Experts provide case-based discussions on interpreting genetic test results, highlighting their impact on clinical decision-making, prognosis, and family planning. The final module looks ahead to the future of renal genetics, covering advancements in testing methodologies, polygenic risk scores, and the potential for precision therapies. Modules two through four are CME-accredited, providing healthcare professionals with an opportunity to earn continuing medical education credits. Visit the series website to watch the recordings and learn about earning CME credit.

Italian Translations of KDIGO CKD Guideline Resources

Translations

Italian translations are now available for key resources from the KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease (CKD). These include the Executive Summary, which outlines the guideline’s key recommendations and evidence-based approaches to CKD care, and two Top 10 Takeaways documents—one focused on best practices for evaluating patients with or at risk for CKD and the other highlighting key principles for managing CKD to slow disease progression and reduce complications. KDIGO thanks Lucia Del Vecchio, MD (Italy), for her time and expertise in translating these important materials. Download the Executive Summary, Top Takeaways for Evaluating CKD, and Top Takeaways for Managing CKD.

Ukrainian Translation of KDIGO 2025 ADPKD Guideline Summary

Translation

A Summary of Recommendations and Practice Points from the KDIGO 2025 Clinical Practice Guideline for the Management of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Guideline is now available in Ukrainian. The summary presents key findings to help healthcare professionals implement guideline recommendations and optimize patient care. KDIGO thanks Dmytro Ivanov, MD (Ukraine), for his time and expertise in producing this translation. Download the Ukrainian Translation of the KDIGO Guideline Summary of Recommendations and Practice Points.

KDIGO-Medscape Webinar: Advancing Chronic Kidney Disease Management in Type 2 Diabetes: Latest Therapies and Practical Insights

On-Demand CME Webinar

The free CME KDIGO-Medscape webinar titled "Advancing Chronic Kidney Disease Management in Type 2 Diabetes: Latest Therapies and Practical Insights" offers healthcare professionals an opportunity to enhance their understanding of managing chronic kidney disease (CKD) in patients with type 2 diabetes. Moderated by Eugene E. Wright Jr., MD (United States), with faculty Peter Rossing, MD, DMSc (Denmark), and Katherine R. Tuttle, MD (United States), this session delves into the latest therapeutic strategies and practical approaches to improve patient outcomes. Participants will gain valuable insights into integrating new therapies into clinical practice. Register.

KDIGO-Medscape Webinar: Mastering Chronic Kidney Disease Care in Type 2 Diabetes: Clinical Case Conversations

On-Demand CME Webinar

​The free CME KDIGO-Medscape webinar "Mastering Chronic Kidney Disease Care in Type 2 Diabetes: Clinical Case Conversations" provides healthcare professionals with valuable insights into managing chronic kidney disease (CKD) in patients with type 2 diabetes. Led by faculty members Janani Rangaswami, MD (United States), and Abhinav Sharma, MD, PhD (Canada), this session utilizes clinical case discussions to explore effective strategies for optimizing patient outcomes. Participants will gain practical knowledge on integrating the latest therapies and guidelines into their clinical practice. Register.

KDIGO Workshop Report on the Nurse's Role in Managing the Symptoms of People Receiving Dialysis

Workshop Report

KDIGO recently published the report from the KDIGO Workshop on the Nurse’s Role in Managing the Symptoms of People Receiving Dialysis. The workshop, held in December 2023, brought together a global group of nephrology nurses, physicians, patient advocates, and healthcare professionals to address the challenges in symptom management and develop strategies to improve outcomes for people on dialysis. Read the report.

Finally, I Can Take a Break from My Itch! Optimizing CKD-aP Treatment

On-Demand CME Webinar

The free CME webinar "Finally, I Can Take a Break from My Itch! Optimizing CKD-aP Treatment" explores the significant impact of chronic kidney disease-associated pruritus (CKD-aP) on patients undergoing dialysis, including its effects on sleep, mental health, and overall quality of life. Led by expert faculty Steven Fishbane, MD (USA), and Alexander M. Voinescu, MD (Romania), this session reviews best practices for discussing symptoms with patients and employing shared decision-making strategies to develop personalized treatment plans. Participants will gain insights into assessing the broader implications of CKD-aP, setting appropriate treatment expectations, and optimizing KOR therapy to improve patient outcomes. Register.

About KDIGO

KDIGO is a Belgian foundation committed to developing and implementing global nephrology guidelines that improve outcomes for people with kidney disease. KDIGO is independent, volunteer-led, self-managed, and accountable to the public and the people it serves. Learn more.