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Kindervelt
The Division of Critical Care Medicine and the Pediatric Intensive Care Unit at Cincinnati Children’s
Summer 2023 Newsletter
Volume 24, Issue 2
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Happy summer everyone! I hope you are enjoying the simple wonders of summer. Take time to feel a warm breeze in your hair, the sunshine on your face and the sand in your toes. The best part of summer is simply spending time outside where the days are longer and the nights are shorter.
How about spending time outdoors on the beautiful grounds of the Western & Southern Tennis facility in Mason Ohio. Kindervelt is, once again, volunteering at the W & S Tennis Open in August. Debbie Clerc needs many volunteers to make this fundraising event happen. Pick a day or evening and come out and join us.
Preparations are underway for our KV Krafts season. Please make note of the upcoming dates in this newsletter. There are many opportunities to help out. Our crafters are talented and I’m sure you will find the perfect unique gift for that special someone.
Mark your calendars for our Fall Event on November 10. Bonnie Hueneman and committee are planning a spectacular Monte Carlo night to remember. You won’t want to miss this fabulous evening.
Enjoy the rest of the summer, as always, thank you for everything you do.
Your friend in Kindervelt,
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Cindy Burger
Kindervelt City President
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“Summer breeze makes me feel fine.”
~ Seals & Crofts
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All flyers are downloadable, just click on the image
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Western & Southern Tennis Fundraising Booth 2023
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Thank you for your interest in volunteering for the 2023 Western & Southern Open Fundraising Booth for Cincinnati Children's Hospital and Medical Center through Kindervelt. We appreciate your help!
This year you will be working on the booth to sell tennis souvenirs and cups of ice. Tennis programs will only be available online. You will be working outside (shaded).
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September 17th - KV #12 Golf Scramble
September 18th - KV #56 Boo Bunco
September 22nd - KV #16 Bunco
October 14th - KV Krafts at Burger Farm
November 4th - KV Krafts Seton High School
November 10th - City Wide Fall Event - Monte Carlo Night
November 15th - KV Krafts at CCHMC
November 25th - West Side Market Craft Show
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Member Highlight - Debbie Linneman
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Debbie Zerhusen Linneman grew up in a large family in Northern Ky and attended Beechwood schools. After graduation she worked many years as a customer service manager at National UnderWriter and Credit Union. She is married to husband, Terry and just celebrated 44 years together. Their family has Jenny (daughter) and Patrick son in law, and two very active grandsons: Cameron and Clayton. Their angel son, Brian died just 2 days after his birth in 1982. He had a very rare condition involving a congenital Diaphragmic Hernia. Baby Brian was rushed to Children's Hospital and had surgery within a few hours. And their grandson, Cameron was born 10 weeks premature weighing only 3lb. 5oz. He stayed in the NICU at Good Sam for 29 days.
Debbie was looking for a chance to support a local charity which worked with babies. As fate would have it, she was in a golf league with Libby Baker. Debbie was invited to attend our KV #56 meeting and see if she was able to join a group which helped raise funds for CCHMC. Since she was so familiar with Children's, a perfect match was made and she jumped in 100%. With Debbie's financial background, she has held the responsibility for all our fundraising endeavors. As KV #56 Treasurer, Debbie has been our money manager for yard sales, bake sales, product sales, silent auctions, craft sales, raffles and more!
She carried over her money finesse as Treasurer for City Board and Financial auditor. She has been treasurer for our Fall Event for many years and is CoChair of KV #56's Silent Auction and Bunco. Speaking of Bunco, Debbie has stated that these events are her very favorite fun fundraisers. She solicits donations, manages reservations, greets our guests, and organizes our raffles, split the pot and gift bags! She feels that our very small group does a great job of presenting our Bunco parties. We have received so many positive responses and so many of our guests have been attending from our earliest years. Many of our guests have become more than friends over the years! And several support our other KV activities. A Bunco guest, Mari has just joined our KV #56 group!
Debbie's outside interests include: attending archery, baseball and football events for both grandsons and gardening with their vegetables and flowers. She enjoyed golf and now really enjoys her trips to Florida and relaxing with their boat on area waterways.
Thank you, Debbie for 25 plus years as a Kindervelt member and making sure our events run smoothly. We know and trust that our funds are always in "good hands". As Mother Teresa says, "The Greatest Good is what We Do for One Another".
Submitted Sheila K. Horan
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I hope everyone is enjoying their summer. I know this is a busy time fitting in all the summer adventures, but I hope you find time to craft. We have our dates set for the KV Kraft Events:
August 8th, Kraft Rep Meeting will be held at Vernon Place, 10am to 12pm, (this is where the Leadership meetings are). We will be sharing exciting new things that are going on this year.
Kraft Show Dates:
October 14, 2023, Burger Farm crafts & baked goods
November 4, 2023, Seton High School, crafts & baked goods
November 15, 2023, Children’s Hospital crafts & baked goods
November 25, 2023, West Side Market (tentative) crafts & baked goods
Please mark your calendars and get ready for a great season. We have a lot of new things happening in Kindervelt Krafts.
Bonnie Hueneman
KV Kraft Chair,
513-235-1122
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KV #16 Congratulations to all the ladies in KV 16 who helped make our 2nd Golf Outing at Clovernook Country Club so much fun while raising lots of money for CCHMC. Rave reviews again and that’s because of all the hard work from Linda Deters and Cindy Burger. Hope to do it all over again in 2024!
KV #19 will be hosting a summer social meeting on August 9th to catch up with each other and meet potential members.
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KV #22 is proud to have leadership at the Western & Southern Open. Stephanie Janssen led the volunteers from (2014-2016) then Deb Clerc and Jackie Kirkpatrick took over from (2017-2019). There was no 2020 tournament during the COVID pandemic in Mason, OH as the event was moved to NYC. Deb Clerc resumed the role in 2021 and is still chairman for 2023. What a wonderful example we've seen in our KV22 friends which shows the dedication and leadership to support Kindervelt Citywide. THANK YOU for your many years of service to such a prominent fundraising event!
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KV #78 Thoughts and love to Ruth Wiley while she is recovering from a fall and being in the hospital.
KV #78 has been crafting away this summer thanks to member Terri Dahlem hosting family, friends and members for these workshops.
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KV #49 Thanks to everyone who supported our Comedy Show at Go Bananas "Let's Laugh For Kid's Sake!" on June 13th! We made almost $10,000!!!
Thanks to Mikee Kurtz, Pippin, and the staff at Go Bananas, as well as the comedians who donated their time and talent - Mark Chailfoux, Lee Kimbrell, Brian Million, Lena Beamish, Kelley Peter, & Mr. T!
We have an amazing group of ladies that worked together to donate & organize raffles, door prizes & split-the-pot, as well as inviting their friends to a fun evening out! That's no joke!
KV #68 would like to thank all their members that are helping make crafts for the fall Kraft shows. We also want to thank everyone that participated in our Golf Outing in May whether you played golf, donated something, volunteered, or sponsored a hole!
WINNERS FOR RAFFLES FOR KV 68 GOLF OUTING
Split the Pot – Liz Schaller
Reds Diamond Seat – Mark Leugering
Bourbon Basket – Laura Favmer
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KV #16 Congratulations to Stephanie Crowley and her family on the birth of their third child. Jack Jerald Crowley weighed in at 8lbs 8oz on June 28.
KV #56 sends congratulation to Nancy Bassarab on the safe arrival of her new granddaughter- Bailey Nicole. Proud parents are Nick and Courtney Bassarab. Brody is proud to receive title of older brother!
Also Congrats to Debbie and Lou Mitsch on the beautiful summer wedding of their granddaughter Kailey. Best wishes to all!
KV #68 Congratulations to Bonnie Hueneman on becoming a great grandmother on May 6th. Her granddaughter Olivia gave birth to a beautiful daughter Vera Jane.
KV #68 Congratulations to Lou Tallarigo on becoming a great grandmother on July 16th. Her granddaughter Molly gave birth to a beautiful daughter Lainey Louise
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KV Board sends deepest sympathies to past City President Linda Smith, who's husband Andy Smith, recently passed away.
KV #19 sends our sincerest condolences to the entire Graham family after learning about the passing of Thomas Graham. The father-in-law of long time KV #19 member, Joan Graham,Tom and his wife, Irene, have been very generous supporters of KV 19 and our Lunch at the Links over the years. The group will be making a donation to Kindervelt in his memory.
KV #68 would like to extend their sincere sympathy to Marge Duffy on the death of her husband Jim Duffy and to Sue Deye on the death of her stepfather.
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August 2nd - Christina Keim #19
August 3rd - Kay Mosier #19
August 4th - Mary Lou Tallarigo #68
August 6th - Mary Stan Fizer #12
August 6th - Jackie Kirkpatrick #22
August 12th - Elaine Santos #77
August 12th - Sarah Varda #77
August 13th - Tammy Brunton #68
August 13th - Kathy Olberding #68
August 13th - Karen Geeves #77
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August 16th - Tina Kasidonis #30
August 17th - Sylvia Norris #12
August 21st - Lizzy Harold #77
August 21st - Mary Beth Young #78
August 22nd - Patti Vetter #68
August 23rd - Phyllis Miller #30
August 24th - Terri Kemper #77
August 26th - Pooja Soni #19
August 29th - Pamela Campbell #12
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Unleashing the potential of human induced pluripotent stem cells (hiPSCs) to better understand the biology of critically ill children with sepsis.
Mihir R. Atreya, MD, MPH
Andrew J. Lautz, MD
Division of Critical Care Medicine, Cincinnati Children’s Hospital Medical Center.
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Sepsis is an abnormal host response to an infection and is a leading killer of children under 5-years of age across the world. Those lucky to survive, are at increased risk of future infections, dependence on medical technologies, and life-long risk of cardiovascular disease. In the U.S alone, care associated with pediatric sepsis exceeds $7 billion each year. However, despite this burden of disease, care for children with sepsis, who are admitted to the pediatric intensive care unit (PICU), remains limited to early antibiotics and intensive organ support through the use of ventilators and dialysis machines. A major obstacle is that patients with sepsis may present with different sources of infection, with different degrees of immune response to the infection, and develop varying degrees of organ failure. An understanding of mechanisms at the cellular and organ-system level, while accounting for these between-patient differences, is therefore necessary to advance sepsis research and ultimately care of patients at the bedside. Currently, this is greatly limited by the amount and type of biological specimens that can be collected from very sick children.
Over the previous decade, researchers at Cincinnati Children’s have pioneered scientific advances in using small amounts of blood or skin cells to turn them into induced pluripotent stem cells (iPSCs) to better understand several complex diseases. Using very little amounts of blood, these human iPSCs can be converted into any cell type of interest, including cells that are usually inaccessible or very rare, to study underlying molecular mechanisms. Moreover, different cell types can be used in combination to develop complex structures called ‘organoids’ in petri dishes. As such, both human iPSCs and organoids are transformative platforms to study patient biology as they capture human genetic diversity and more closely mimic patient biology in comparison with traditional mouse models. Most importantly, iPSCs are a renewable resources of patient specimens, which is a critical consideration for pediatric patients. These research efforts have been bolstered by the investment in state-of-the-art institutional facilities including the Pluripotent Stem Cell Facility (PSCF) and Center for STem cell and Organoid Medicine (CuSTOM).
An investigator team lead by faculty in our division has recently secured federal funding through a phased innovation award by the National Institute of General Medical Sciences (NIGMS), a key institute under the National Institutes of Health (NIH), to test whether human iPSCs derived from critically ill children with sepsis can be used to develop more relevant and reproducible disease models for future studies. The key goals of the project are to (1) validate new approaches to blood specimen collection, (2) to generate patient-specific iPSCs, and (2) to use high throughput sequencing approaches to determine how closely iPSCs can recapitulate patient biology at the genetic level. This collaborative proposal builds on our long-standing multi-center pediatric sepsis biorepository led by the late Dr. Hector Wong and provides us the opportunity to transform it to meet the needs of the next generation of scientific inquiry. Ultimately, we hope that our patient-specific human iPSC biorepository will help unravel patient biology through advanced organoid models, accelerate mechanistic research, and lead to the discovery of precision therapeutics that can meaningfully improve outcomes of critically ill children with sepsis.
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Kindervelt | 513-636-0293 | 3333 Burnet Ave, MLC 9002, Cincinnati, Oh 45229
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