LDA NEWS & UPDATES 

February 28, 2023

 Attention: Save the Date!

   Lyme Disease Association Inc - Columbia University

 

2023 Lyme & Other Tick-Borne Diseases CME Conference

 

      Friday & Saturday, October 13,14, 2023 

Lyme Vaccine Trial Sites Shut Down: Practice Violations

Third Party Site Issues Undisclosed

Nantucket Current (Graziadei, J.) 2.18.23, reported that Pfizer has shut down its Lyme disease vaccine trial site in Nantucket. Pfizer informed all Lyme disease vaccine clinical trial participants that the site was shut down “following potential violations of Good Clinical Practice (GCP) at clinical trial sites operated by a third party.” Read more.

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Borrelia Associated with ANAs?

Read the abstract.

FM Patients with ANA Show Borrelia Spp. Activity

Current Rheumatology Reviews (Puri, B.K., et al.) 2.15.23, published, “Antinuclear antibody seropositivity in fibromyalgia associated with Borrelia-specific T lymphocytes.” The study sought to test the hypothesis that patients with fibromyalgia who were antinuclear antibodies (ANAs) positive were more likely to show Borrelia spp. specific T lymphocyte activity. Read more.

POTS Associated with COVID Infection and Vaccination

Important Study, Further Research Needed

JAMA (Rubin, R.) 1.25.23 published “Large Cohort Study Finds Possible Association Between Postural Orthostatic Tachycardia Syndrome and COVID-19 Vaccination but Far Stronger Link With SARS-CoV-2 Infection.” The article provides an overview of a study that analyzed data from the electronic health records of nearly 285,000 individuals who received a COVID-19 vaccine at Cedars Sinai Medical Center in Los Angeles – a majority of which were an mRNA type. Read more.

Read the study.

COVID-19 Rebound in Some Patients Who Take Paxlovid

Read the advisory.

Still Recommended for High Risk Patients

JAMA (Rubin, R.) 6.8.22 published “From  Positive to Negative to Positive Again - The Mystery of Why COVID-19 Rebounds in Some Patients Who Take Paxlovid.” The author provides an overview of the incidence of COVID rebound cases in patients who had taken Pfizer’s antiviral nirmatrelvir/ritonavir, aka, Paxlovid. In late spring of 2022, rebound cases were being reported in medical literature and on social media, urging the CDC's Health Alert Network to issue a health advisory on May 24, 2022. Read more.

Case: Reversible Dementia Caused by Lyme Disease

Improvement After Doxycycline Therapy

Annals of Geriatric Medicine and Research (Sanchini, C., et al.) 2.6.23, published “A case of reversible dementia? Dementia vs delirium in Lyme disease.” The report details the case of a 75-year-old man who was admitted to the Alzheimer’s Disease Care Unit of the Institute Golgi (Abbiategrasso, Italy). Read more.

Read the report.

LDA President’s Blog: The Quiet Epidemic

Read about the film.

How Misuse & Suppression of Science Harms Patients

Today I took time out of my schedule to watch a movie, one I’d heard about but not seen, one that deals with an issue I have advocated and educated for over 39 years. After four decades, people ask me why do I continue to volunteer for the Lyme disease cause. This movie lays it out; my life flashed before my eyes, emotions tore at my heart - anger and sadness - and brought me to tears. The Quiet Epidemic is a journey through the often times sordid history of Lyme to the present through the words and deeds of some of the most competent and giving scientists and doctors in the Lyme movement, including doctors Brian Fallon, Rich Horowitz, Ken Liegner, and others too numerous to mention. Read more.

Babesia Divergens Study

Antiparasitic Target Pathways in Host Red Blood Cells

Microbiology Spectrum (Beri, D., et al.) 2.14.23, published “Global Metabolomic Profiling of Host Red Blood Cells Infected with  Babesia divergens Reveals Novel Antiparasitic Target Pathways.” The study used a high-resolution global metabolomics method to reveal the metabolic interactions between the apicomplexan parasite, Babesia divergens, and host red blood cells. Read more.

Read the study.

Ticks and Tick-Borne Diseases in the Arctic

Close Monitoring Recommended

Karen D. McCoy, et al., published “Climate change in the Arctic: testing the poleward expansion of ticks and tick-borne diseases” in Global Change Biology on January 26, 2023. In this article, researchers tested the hypothesis that Ixodes uriae (seabird tick) has expanded poleward to the high Arctic in response to climate changes during the past twenty years. Read more.

Ixodes uriae, James L. Occi, PhD LDA Scientific Advisory Board

Read the study.

Baltimore Man Awarded Nearly $800,000

Read the article.

Misdiagnosed Lyme Lawsuit

The Daily Record, Maryland, (O’Neil, M.) 2.7.23, published an article regarding a Baltimore man who was awarded a $792,000 jury verdict after medical care providers at Patient First Primary and Urgent Care, Catonsville, misdiagnosed severe Lyme disease symptoms in the patient. The jurors concluded that the medical care provider breached the standard of care for this patient. Read more.

Jury Awards Parents $6.5 M

Lyme Misdiagnosis Resulting in Death

According to BangorDailyNews.com, Judy Harrison, 2.2.23, the Mercy Hospital, Northern Light Health, Maine, has been found guilty in a wrongful death lawsuit filed by the parents of Peter A. Smith. Smith twice saw the same doctor at the hospital in June 2017 but was never diagnosed with Lyme disease. The doctor noted on a visit, “No signs of Lyme disease." Read more.

Read the article.


Read another article on the jury award.

Tick Reduction Efforts: No Decrease in Lyme Cases

Read the study.

No Significant Reduction of Incidence in Humans

Emerging Infectious Diseases (Keesing, F., et al.) 5.22, published “Effects of Tick-Control Interventions on Tick Abundance, Human Encounters with Ticks, and Incidence of Tickborne Diseases in Residential Neighborhoods, New York, USA.” The researchers conducted a large-scale study to determine effectiveness of the Tick Control System (TCS) and Met52 fungal spray in reducing case numbers of Lyme disease. Read more.

Cattle Effects on Vector-Borne Disease Human Risk

A Systematic Review

medRxiv (Chakraborty, S., et al.) 2.9.23 published “Effects of cattle on vector-borne disease risk to humans: A systematic review.” The researchers’ aim was to shed light on different ecological systems that are affecting human risk for contracting vector-borne diseases (VBDs) from cattle. Read more.

Read the study.

CDC Foundation Collaboration with Groups Key

Jeannine Phillips

LDA Meeting Report

Lyme Disease Association, Inc. (LDA) Board of Directors Member, Jeannine Phillips, attended the first virtual meeting of ICUE, the CDC Foundation’s new infectious disease-based initiative, February 8, 2023, which includes Lyme disease. About 40 patient advocacy and community-based organizations from different health conditions were represented in the initial endeavor. Read the meeting report.

Study Examines Persistent Powassan Disease in Mice

What Causes Long-Term Neuro Symptoms?

mBio (Scroggs, S., et al.) 2.21.23, published “Of Murines and Humans: Modeling Persistent Powassan Disease in C57BL/6 Mice.” The purpose of the study was to better understand how Powassan virus lineage I (POWV) and lineage II (known as deer tick virus [DTV]) cause long-term symptoms in addition to examining the potential role of viral persistence for the purpose of therapy development. Read more.

Read the study.

Molecular Detection of Bartonellosis

Bartonella henselae


Read the study.

Improving Diagnostics

Emerging Infectious Diseases (McCormick, D.W., et al.) 3.23, has published a Medscape Continuing Medical Education (CME) Activity; “Bartonella spp. Infections Identified by Molecular

Methods, United States.” The authors describe how molecular methods of testing can provide identification of Bartonella spp. infections which are difficult to diagnose using culture or serology. Read more.

Vertical Transmission of TBDs in Ticks

May Increase Potential for Spread of Diseases

Parasitology Research (Ravindran, R., et al.) 2.17.23, published “Transovarial transmission of pathogenic protozoa and rickettsial organisms in ticks.” This article provides a review and updated summary of previous reports of vertical transmission of pathogens, transovarial transmission (TOT), which is the transmission of an infectious agent from parent to offspring via infection of the developing egg. This mode of transmission has been observed in many tick vectors and may increase potential for spread of diseases. Read more.

Credit: James Occi, PhD., Rutgers University

Read the study.

Limbic System Retraining: A Tool to Heal Lyme?

More information.

“Great to Astonishing” Recovery 

On February 22, 2023, The International Lyme and Associated Illnesses Society (ILADS) hosted a webinar with Annie Hopper, a limbic system rehabilitation specialist and founder of the Dynamic Neural Retraining System. Hopper states that she has found great success with this process in her own healing and has dedicated her life to help others recover. Read more.

Colorado Tick Fever Increase in Montana

Heightened Sensitivity of Molecular Method Testing

Emerging Infectious Diseases (Soto, Raymond A., et al.) 3.23, has published “Increase in Colorado Tick Fever Virus Disease Cases and Effect of COVID-19 Pandemic on Behaviors and Testing Practices, Montana, 2020.” The authors describe a large reported increase in Colorado tick fever (CTF) cases in Montana in 2020. CTF is a virus transmitted primarily by Rocky Mountain wood tick (Dermacentor andersoni). The authors present their subsequent case-control study of residents who tested positive during 2020 for CTF. Read more.

Female & Male Rocky Mountain wood ticks. Credit: James Gathany-CDC/Dr. Christopher Paddock.

Read the study.

The Lyme Disease Association Inc. (LDA) does not charge any membership fees. Most of our

materials are free to download and most of our videos are free on YouTube. Our nationwide

doctor referral system is free to access. Printed brochures can be ordered for the cost of S&H.  

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