IRA holders have to take their Required Minimum Distribution (RMD) each year, but in case you haven't and you are age 70-1/2 or older, the law is now permanent that you can donate to charity out of that RMD and not have it counted as taxable income.
To donate out of your IRA RMD, please contact your IRA administrator and have them transfer the money directly to a 501c3 charity. If you take the cash first, it won't be tax deductible. Also, the cap is $100,000 per IRA account, so you and your spouse can both do it if you have separate IRA accounts.
If you want to use your RMD to start (or add to an existing) fund here at The Community Foundation, please keep in mind that you cannot deposit your RMD into a donor advised fund. However, other types of funds are eligible and achieve nearly the same end result - designated, field of interest, and scholarship funds are great alternatives to DAFs!