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Weekly Update

January 22nd, 2025

Upcoming SoCalBio Events

Best Practices for Managing Critical Property Exposures

Tuesday, February 4 · 10 - 11 am PST

Virtual


Join SoCalBio, Chubb Insurance, and IMA Financial Group for a webinar to discuss the state of the property market in California and best practices for managing critical property exposures. Registration for this event is free for SoCalBio members!


Register now!
Register now!

SOCALBIO Networking Mixer in Valencia

Thursday, February 27 · 4 - 7pm PST

@ Humannity Medtech


Join us for an exciting evening of networking in Santa Clarita's vibrant life science scene. Mingle with fellow professionals from biotech, medical device, diagnostics, and digital health companies in the region. Let us know how SoCalBio can better serve your company. Registration for this event is free for SoCalBio members!


SoCalBio's Partner Events

11th Annual

American Biomanufacturing Summit

April 15-16, 2025 - San Francisco, CA


Join over 200 biopharma and biotech executive leaders at our annual biomanufacturing conference! Over our two-day event, top biopharma executives and solution providers come together to discuss emerging key trends, challenges, opportunities, and innovations in the biotechnology industry.

Learn more

News Updates

‘The bar has risen’: China’s biotech gains push US companies to adapt | BioPharmaDive

A fast-improving pipeline of drugs invented in China is attracting pharma dealmakers, putting pressure on U.S. biotechs and the VC firms that back them.


Top healthcare technology trends in 2025 | MedTechDive

How the incoming Trump administration will regulate AI this year remains unclear. Meanwhile, experts say healthcare companies will continue bolstering cyber defenses to withstand increasing attacks.


US FDA announces plans to address medical device shortage risks | Vascular News

The US Food and Drug Administration (FDA) has issued a statement outlining measures to enhance protections against medical device shortages.


Odyssey, Sionna join band of biotechs ready to brave thawing IPO waters in 2025 | Fierce Biotech

Odyssey Therapeutics and Sionna Therapeutics have filed IPO paperwork, swelling the pack of startups that will provide an early look at how receptive public investors could be to biotech listings in 2025.


Trump rolls back Biden directive to study methods of lowering prescription costs | The Hill

On his first day, President Trump rescinded an executive order exploring new healthcare payment models to reduce prescription costs for Medicare and Medicaid beneficiaries.


Ozempic is in the next round of Medicare drug price negotiations. See the full list of 15 medications | CNBC

The Biden administration unveiled the next 15 prescription drugs that will be subject to price negotiations between manufacturers and Medicare.


Is biotech M&A set to surge in 2025? | Labiotech

Mergers and acquisitions (M&As) are a cornerstone of the biopharma industry, often leading to success stories. In 2024, the sector faced a decline in M&A activity, with total transaction values dramatically lower than in 2023. Experts viewed last year as a “reset” year, with companies focusing on smaller strategic deals instead.


FDA approves standalone use of J&J's ketamine-derived depression treatment | Reuters

The U.S. Food and Drug Administration expanded approval for Johnson & Johnson's nasal spray, Spravato, to allow it to be used as a standalone treatment for patients with severe depression, the company said on Tuesday.

NCI SBIR MATCHUP Program

Connecting NCI SBIR/STTR-funded small businesses and the next generation of scientists


The Mentor And Trainee Connections Hub Program (MATCHUP) by NCI SBIR connects trainee scientists with small businesses that have NCI small business funding. Partners through MATCHUP are then encouraged to apply for an Administrative Supplement to Promote Diversity, which provides funding for trainee scientists to work on an NCI SBIR-funded project.


For more information, click here!

Special Saving on Lab Supplies

Become a member of SoCalBio and enjoy fantastic savings on lab supplies from Avantor's extensive catalog through SoCalBio's Group Purchasing.

Learn More!

1000% markups: FTC report blasts PBMs


Pharmacy benefit managers (PBMs) make billions in profit while driving up the price of prescription drugs with markups exceeding 1,000%, says a new Federal Trade Commission (FTC) report.


The takeaway: The three largest PBMs and affiliated pharmacies earned $7.3 billion in revenue above the National Average Drug Acquisition Cost (NADAC) on specialty generic drugs alone during 2017-2021, according to the FTC’s second report on “the prescription drug middleman industry.”


A focus on specialty drugs: After FTC’s July report highlighted PBMs’ vertical integration with insurers and pharmacies, this report shows how PBMs use market power to profit from hiking prices on specialty generic drugs, which target conditions like cancer, HIV, or rare diseases.


A few more findings:

  • Drugs are marked up “hundreds and thousands of percent.”
  • PBMs steer profitable prescriptions to affiliated pharmacies.
  • PBMs bill sponsor clients more than they reimburse pharmacies for drugs.
  • Patients’ and plan sponsors’ spending on drugs increased significantly.
  • Specialty generic drugs are a major profit driver for the three largest PBMs.

BIO has long called for PBM reform, explaining how PBMs cause patients to lose out on rebatesindependent pharmacies to close, and drug prices to rise (among other abuses).

Read more in Bio.News.



What patients need to know about Medicare Part D changes


To help patients navigate important Medicare Part D changes, Bio.News asked the National Health Council (NHC) to explain what’s new.


Out-of-pocket cap: The highest-profile change to Medicare in 2025 is a $2,000 per year limit on beneficiary costs for prescription drugs, including copays and coinsurance.


Smoothing: Patients can spread drug costs out over the year but must enroll in the Medicare Prescription Payment Plan (MPPP).


To help patients understand and navigate these changes, NHC, Medicare Access for Patients Rx (MAPRx), and several other patient advocacy groups launched outreach and education campaigns. “Medicare is rolling out several new benefits in 2025,” explains the NHC. “These new benefits may be confusing to beneficiaries, and coupled with other big changes, may result in Medicare plans looking very different going forward.” NHC is eager to hear how the new changes and enrollment systems are affecting patients or caregivers. To share your experience (good, bad, or indifferent), you can contact MedicarePartD@nhcouncil.org.


More people are eligible for the Low-Income Subsidy Program, which provides reduced Part D costs for patients with limited income. Beneficiaries with an income of up to 150% of the federal poverty level are now eligible.


Do you have questions? NHC and MAPRx have resources, and Bio.News has more insights.

Learn More!

Southern California Biomedical Council 401(k) Retirement Plan Exchange® now available in partnership with Gallagher, TAG Resources, and Transamerica.


Our solution makes it easy by offering employers a professional suite of recordkeeping, administrative, fiduciary, and investment management services.

Learn More!

New Real Estate Oppotunity In Anaheim

3071 E. CORONADO STREET, ANAHEIM, CA


  • 7,665 SF of Corporate Image Office Area (Two Story)
  • 32’ minimum warehouse ceiling clearance
  • ESFR sprinkler system with K25 sprinkler heads
  • 12 dock-high loading doors
  • 139 parking stall
  • 2 ground level loading doors
  • Concrete throughout loading area

Local Highlights

Do you have a recent scientific breakthrough, investment milestone, or commitment you would like to share? We are always looking to share our member's stories Submit your stories to scbc@socalbio.org

Adagene to Announce Updated Data from Phase 1b/2 Study of Muzastotug in Combination with KEYTRUDA® (pembrolizumab) in Colorectal Cancer at ASCO Gastrointestinal Cancers Symposium


Inhibrx Biosciences Announces Preliminary Data from the Phase 1 Trial of ozekibart (INBRX-109) for the Treatment of Colorectal Cancer


Dermata and Revance Enter Clinical Trial Collaboration Agreement for the Topical Application of Xyngari(TM) with Daxxify(R)


Evolus Announces Preliminary Unaudited Fourth Quarter and Full-Year 2024 Net Revenue, Achieving Record Results at the Top of the Company’s Guidance


CovarsaDx® Research Team Provides Key Support for the FDA 510(k) Clearance for OSANG Healthcare’s Over-The-Counter QuickFinder™ COVID-19/Flu Antigen Self-Test and QuickFinder™ COVID-19/Flu Antigen Pro Test


Kairos Pharma Provides Business Update and Outlook into 2025


ViaDerma, Inc. Strengthens Global Expansion with New Dubai Office and Progress Towards Product Registration in India


ARS Pharmaceuticals Launches neffyinSchools Program Providing Free Life-Saving Needle-Free Epinephrine For Emergency Use to Eligible K-12 Schools


Revelation Biosciences Starts its PRIME Phase 1b Clinical Study of Gemini in CKD Patients


Tanvex BioPharma Completes Acquisition of Bora Biologics, Launching New Era in Biologics Development


United Arab Emirates Ministry of Health and Prevention Approves Biomerica’s Fortel® PSA Screening Test to Detect an Early Sign of Prostate Cancer


Pancreatic Cancer Diagnoses and Mortality Rates Climb; Five-Year Survival Rate for Pancreatic Cancer Stalls at 13%


Beckman Coulter Introduces Cutting-Edge Research Use Only Assays for Neurodegenerative Disease Research

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