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Weekly Newsletter

April 16th, 2025

Upcoming SoCalBio Events

Register now!

Last Chance to Register !


SOCALBIO Networking Mixer in

Pasadena

Thursday, April 17 · 4 - 7 pm PST

@ Pasadena Bio Collaborative


Join us for an evening of networking! Connect with professionals from Pasandena's biotech, medtech, and digital health sectors while enjoying great food and drinks.

The Pasadena Bio Collaborative Incubator is a non-profit organization created to support the growing number of life science start-ups in the Pasadena area. 

News Updates

A judge blocked the FDA’s plan to regulate LDTs. What now? | MedTechDive

One attorney said the ruling “isn’t quite the stake in the heart.” The FDA is unlikely to challenge the court’s decision, but Congress could still take on the issue.


Trump health policy uncertainty sends biotech sector into deeper slump | Reuters

Trump administration cuts to federal health agencies have sent shivers through a biotech industry already facing a downturn, raising concerns about increased difficulty in getting products approved, investors, executives, and analysts said.


U.S. trails China in race to utilize biotech on the battlefield | Axios

A critical avenue of U.S.-China competition has slipped under the public's radar despite its potential outsize impacts on economies, militaries and weaponry: biotechnology.


Medical product manufacturers are divided over Trump’s tariffs | CNBC

Medical technology, medical device and hospital trade groups are pushing the Trump administration for tariff exemptions on medical equipment


HHS delivers stop work order to Atlanta biotech, pulls funding | Fierce Biotech

The U.S. government continues to end contracts related to the $5 billion Project NextGen initiative, this time terminating funding for an Atlanta biotech’s lead COVID-19 vaccine program that’s currently being tested in a mid-stage trial.


Trump executive order backs change to Medicare negotiation pushed by drug industry | The Hill

Health and Human Services Secretary Robert F. Kennedy Jr. said he was unaware that his agency was trying to rescind more than $11 billion from state and local health departments. 


New research kindles excitement around stem cell therapies for Parkinson’s | BioPharmaDive

Two studies published in Nature found stem cell-derived products can not only be safely transplanted into the brain, but also show promising — albeit unproven — signs of efficacy.


The AI race in biotech: Is Europe falling behind the US and China | Labiotech

Since the blockbuster release of OpenAI’s ChatGPT in 2022, artificial intelligence (AI) has infiltrated every industry, especially biotech, where many companies have adopted it in recent years for various tasks, particularly in drug development.

Applications Now Open for the 2025 SoCalBio Annual Investor Conference!


Showcase your company to a network of angel investors, venture capitalists, and industry leaders at the 2025 SoCalBio Annual Investor Conference. In 2024, we had over 20 investors and over 200 one-on-one meetings scheduled.


Applicants will undergo a screening process with our Innovation Catalysts Committee. Selected companies will receive complimentary admission to the conference to present, as well as early registration for 1:1 networking meetings with investors.

Apply to today!

SoCalBio Workforce Development Committee needs your help!


Workforce Development Survey: Internships & Apprenticeships

We are conducting a brief survey to better understand how our members engage with internships and apprenticeships as part of their workforce development strategies. Your insights will help us identify trends, gaps, and opportunities to support talent development across our industry.


Your feedback is valuable and will directly inform future initiatives, partnerships, and advocacy efforts. The survey should take no more than 5 minutes to complete.


Thank you for helping us shape a stronger, more sustainable workforce pipeline.

Access survey here!

Tariffs still threaten biotech


President Trump’s planned “major tariff on pharmaceuticals,” which aims to force U.S. onshoring of manufacturing, is still on the table.


The news: U.S. Treasury Secretary Scott Bessent said Wednesday the 90-day pause on most country-specific “reciprocal” tariffs would not apply to sector-specific tariffs, such as pharmaceuticals, The Washington Post reports.


Why it matters: Last year’s BIO member survey said reshoring or “friend-shoring” manufacturing could take eight years. BIO’s survey last month showed tariffs would delay or stop innovation, harm investment, and reduce patient access to medicine.


Agricultural biotech is also vulnerable. U.S. agriculture is a prime target for tariffs and trade disputes would foil efforts at speeding regulation of new biotech traits in foreign markets. (Read more.)


Concerns about pharma tariffs were aired by Reps. Nicole Malliotakis (R-NY), Lloyd Doggett (D-TX), Mike Thompson (D-CA), and David Schweikert (R-AZ)—who said the U.S. lacks the infrastructure for onshoring—in a House Ways and Means hearing questioning U.S. Trade Rep. Jamieson Greer.


BIO’s view: “Re-onshoring key parts of the biotechnology supply chain to the U.S. and our allies and strengthening the American manufacturing base should be a high priority for both national and economic security. It will take years, though, for this shift and we need to be mindful of the negative consequences of these proposed tariffs,” according to BIO President & CEO John F. Crowley.



Drugs for rare diseases afflicting children “rarely make enough money to fund the incredibly expensive research underpinning them,” writes Neil Kumar, CEO of BridgeBio, in STAT News. “So instead of expensive taxpayer-funded grants or subsidies, the government has another way to make up the shortfall. Companies that successfully bring a treatment for a rare pediatric disease to market get a voucher for a speedy FDA review that can be used for a different, unrelated drug.” Kumar explains how the PPRV incentivized a breakthrough by his own company and urges passage of the Give Kids a Chance Act of 2025 to reinstate the PPRV.


Special Saving on Lab Supplies

Become a member of SoCalBio and enjoy fantastic savings on lab supplies from Avantor's extensive catalog through SoCalBio's Group Purchasing.

Learn More!
 
 

Local Highlights

Do you have a recent scientific breakthrough, investment milestone, or commitment you would like to share? We are always looking to share our member's stories Submit your stories to scbc@socalbio.org

NEURELIS ANNOUNCES FDA APPROVAL FOR IMMEDIATE USE SEIZURE MEDICATION VALTOCO® (DIAZEPAM NASAL SPRAY) IN AGES 2 TO 5


Innovive Expands into Latin America & Caribbean Through a New Distribution Partnership with EAD Scientific


Skye Bioscience Demonstrates Over 30% Weight Loss with Nimacimab and Tirzepatide Combination in Preclinical Model


Dermata’s XYNGARI(TM) Phase 3 Trial Hits Statistically Significant Difference at 4 Weeks


Er-Kim Announces Exclusive Distribution Agreement with Polaris Pharmaceuticals to Commercialize Pegargiminase (ADZODI) for Malignant Pleural Mesothelioma (MPM) in Multiple EMEA Markets


SpineX Inc. Announces Significant Improvement in Urinary Bladder Function in Paralyzed Individuals with SCONE™ Therapy


Cardiff Oncology Announces Completion of Enrollment in Phase 2 CRDF-004 Trial Evaluating Onvansertib for the Treatment of First-line RAS-mutated Metastatic Colorectal Cancer


Ensysce Biosciences Announces Positive Data from Opioid Overdose Protection Study


Toragen, Inc. Provides Update on Phase 1 Clinical Trial of TGN-S11 as Monotherapy and in Combination with Keytruda® in Patients with Stage 4 HPV-Associated Cancers


Fate Therapeutics Receives Regenerative Medicine Advanced Therapy (RMAT) Designation from FDA for FT819 to Treat Moderate to Severe Systemic Lupus Erythematosus (SLE)


Ainos Secures TFDA Approval and IRB Clearance to Advance VELDONA Clinical Trials for HIV Oral Warts and Sjögren’s Syndrome in Taiwan


IMDELLTRA® DEMONSTRATED SUPERIOR OVERALL SURVIVAL IN SMALL CELL LUNG CANCER


BioCardia Initiates Patient Enrollment at Emory University School of Medicine for Ongoing CardiAMP HF II Pivotal Study


Oncolytics Biotech® and Pelareorep Discussed During Recent H.C. Wainwright Key Opinion Leader Event on Oncolytic Immunotherapies in Breast and Pancreatic Cancers


Dexcom G7 15 Day Receives FDA Clearance: the Longest Lasting Wearable and Most Accurate CGM System


Palisade Bio Completes Dosing in Phase 1a Portion of Ongoing Phase 1a/b Study of PALI-2108


The Irresistible Offer Formula: Close Deals Faster in MedTech

For MedTech, medical device, and life science leaders:

Part 1: Nail Your Unique Offer

Define what sets you apart:

  • What? The only [your product].
  • How? That [unique feature].
  • Who? For [audience].
  • Why? Who want [core desire].
  • When? In an era of [industry challenge].

Example: The only AI surgical tool that optimizes procedures for hospitals who want faster surgeries and lower costs, in an era of tight budgets.


Why It Works: Sharpens your focus to grab decision-makers’ attention.

Part 2: The Value Equation

Four components make your offer irresistible:

  1. Dream Outcome
  • What: Promise the goal they crave.
  • Examples: Shorter surgeries; 25% better outcomes; 20% cost savings.
  • Why: Hits their pain points—efficiency, results, profits.
  1. Likelihood of Achievement
  • What: Build trust with proof.
  • Examples: Guaranteed results; 15 hospitals succeeded; works despite your current possible tech gaps.
  • Why: Eases healthcare’s risk-averse mindset.
  1. Time Delay
  • What: Show fast impact.
  • Examples: ROI in 30 days; instant setup in < 2 days; savings in a week.
  • Why: Fits their need for quick wins.
  1. Effort/Sacrifice
  • What: Remove barriers.
  • Examples: No complex training; 50% less setup; no costly contracts.
  • Why: Makes adoption easy for busy teams.

Why They Win Together

  • Dream hooks with big wins.
  • Likelihood builds confidence.
  • Time delivers speed.
  • Effort clears hurdles.


For MedTech, this formula cuts through budget constraints and skepticism, aligning with what decision-makers need to act.

 Free Strategy Session: Elevate Your MedTech Outreach

Are you already selling your MedTech product or service to potential clients? 

Book a complimentary Irresistible Offer Drive-Through with Lucid Strategies.

Limited Availability: Secure your spot today.

Schedule Now: Book a Meeting (FREE)


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