Can't see the full newsletter? Please accept images and add Lawson LEADS (lawsonresearch-sjhc.london.on.ca@shared1.ccsend.com) to your safe list. | | Bridging worlds: Bringing partners together to advance care and recover | | On Sept. 15, the MacDonald Franklin OSI Research Centre at Lawson hosted the national Research Impact Summit in Toronto, bringing together nearly 40 experts from Veterans Affairs Canada, the Department of National Defence and other sectors. The event focused on integrating treatment and prevention, sharing knowledge, supporting families, connecting mental and physical health and fostering collective impact. Andrey Andriets, Lawson Director of Research Strategy and Operations, highlighted Lawson’s leadership in workplace injury research, supported by the Workplace Safety and Insurance Board. By connecting experts and sharing insights, the Summit demonstrated how research collaboration drives meaningful progress for military members, veterans and others affected by occupational trauma. | | Mental health and addiction system innovation pitch | |
| | | On Oct. 3, MINDS of London-Middlesex hosted the Mental Health and Addiction System Innovation Pitch, an event bringing together local professionals passionate about addressing the complex challenges faced by youth in London-Middlesex's mental health and addiction system. Researchers, clinicians and community members listened to bold, courageous and creative solutions designed to enhance patient care and support recovery. The event showcased three innovative pitches: one leveraging social media to improve system navigation, another using storytelling and engaging content to educate about cannabis use and a third introducing a proactive support model that connects youth on waitlists with community resources, transforming delays into opportunities for growth. This event was the culmination of the Mindful Social Innovation Training Program, spearheaded by Lawson scientist, Dr. Arlene MacDougall. To learn more about the program, the pitch ideas shared, and how you can become a mindful social innovator, please reach out to Dr. MacDougall.
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Lawson Research Day: A celebration of discovery
On Oct. 16, Lawson marked its first anniversary since its relaunch with vibrant booths across St. Joseph’s, connecting staff, trainees and community members. The day showcased research excellence, sparked collaboration and featured sweet treats and swag for visitors. From inspiring conversations to renewed energy for innovation, the event reflected our shared commitment to advancing care through research. View event photos online and relive the moments that made this celebration unforgettable. Congratulations to our door prize winners: Ryan Hutchison, Cyndi Thompson, Madi Williams-Choquette, Megan Fluit, Diana Laviolette and Emily Kuchta. A special thank you to everyone who helped and attended!
| | Clinical trials are a vital part of how new treatments, devices and care strategies are discovered, tested and improved for patients. In October, Lawson supported 833 clinical research studies, underscoring the dedication to advancing patient-centered medical innovations. Visit Lawson’s Webpage to discover more about our clinical trials and how to get involved. | | |
New Alzheimer's drug offers hope to patients and families
Dr. Michael Borrie, Lawson scientist and Medical Director at St. Joseph’s, was interviewed about lecanemab, a newly approved drug that slows early Alzheimer’s progression. He emphasized strong local interest and noted that testing is underway. While not a cure, the treatment offers families valuable time. Lecanemab is the first drug approved by Health Canada for Alzheimer’s in 20 years. Read the complete viewpoint from Dr. Borrie and find further details about this breakthrough by visiting: CBC, London Free Press and Meltwater. Share the news on Instagram
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Minding the mysteries of Alzheimer's Disease
The London-based BioMIND study continues to test a triple assessment of brain scans, blood draws and lumbar punctures to help identify Alzheimer’s Disease in people exhibiting early signs of memory loss and cognitive impairment. Donor support through St. Joseph’s Health Care Foundation fuels this ongoing clinical trial research. Read more on the Foundation’s website.
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Clinical breakthrough in prostate cancer
London researchers from St. Joseph’s, London Health Sciences Centre and Western University led a major clinical trial testing a new method to detect prostate cancer more accurately. Conducted from 2018 to 2022, the study used radioactive blood tracers that target prostate cancer cells with Positron Emission Tomography (PET) scans. The study involved 1,500 men in Ontario and showed improved survival and quality of life. This test is now available through OHIP. Read the full story
| | Explore the world of pragmatic clinical trials with HDRN Canada Pragmatic Trials Training Program | | |
Each week, the program releases open-access learning modules that dive into key aspects of trial design and implementation - from randomization and data analysis to truth and reconciliation in pragmatic trials. Whether you’re a clinician, researcher, or health professional, these modules offer practical insights to strengthen your understanding of how trials can improve real-world care. Discover the full series at pragmatictrialstraining.ca
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RESEARCH TIP
Ready to make your CV stand out? When preparing your Tri-agency Narrative CV, focus on telling the story of your research impact, leadership and contributions. Use the CIHR video resource and Western’s Narrative CV guide for practical examples and advice.
Register for the Research Impact Canada's Professional Development (PD) virtual webinar on "Navigating Narrative CVs in Canada on Nov. 18 11:30 am - 12:30 pm MT.
Clear compelling narratives help reviewers see your unique strengths.
| | | | Mandatory use of new informed consent template for clinical trials - effective January 1, 2026 | | |
Beginning January 1, 2026, the Health Sciences Research Ethics Board (HSREB) will require the use of a standardized informed consent form template for all new clinical trial applications.
Western University’s template has been developed in alignment with the Clinical Trials Ontario (CTO) model to promote consistency across institutions in Ontario and to reflect feedback from industry partners who are now familiar with this format. The template also integrates the documented institutional ethics requirements applicable to research conducted at London’s hospitals.
This requirement will apply to all clinical trials. The new informed consent template is available on the Western Research website under the HSREB guidelines section.
Please note: For non-clinical trial submissions, the current Letter of Information/Consent (LOI/C) guidance documents will continue to apply.
For further information or clarification, please contact the Office of Human Research Ethics at ethics@uwo.ca
| | Notice of institutional adoption of ICH GCP E6(R3) - Effective April 1, 2026 | | |
The International Conference on Harmonization (ICH) has recently made significant updates to the Good Clinical Practice (GCP) guidelines. ICH GCP E6 (R3)
Health Canada's official adoption of the revised GCP E6 R3 guideline is scheduled for April 1, 2026.
The updated ICH GCP E6(R3) training module is now available through CITI. To ensure a smooth transition, we encourage all research personnel to complete the revised training at their earliest convenience.
Please note: If not done prior, completion of the updated CITI GCP E6(R3) training will be mandatory starting April 1, 2026 for all new and existing clinical trials.
For questions or assistance, please contact: researchqualityandeducation@sjhc.london.on.ca
| | Office of Research Services | | |
Macarena Pampillo, PhD, serves as the Grant Development Manager at the ORS. With over a decade of experience in research administration, a certificate from Mohawk College in research administration and extensive background in bench research, she brings deep expertise to the team. After earning her PhD in Neuroendocrinology in Buenos Aires, she pursued postdoctoral research at Robarts Research Institute. Then, Pampillo managed a confocal microscopy core facility and worked in research labs at Victoria hospital for nearly ten years before joining ORS in 2015, where she advanced from Grant Development Officer to manager. She oversees daily operations of the team, focuses on large strategic funding applications, leads internal review processes and patient engagement in research initiatives and collaborates with internal and external stakeholders.
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Niveen Fulcher, PhD, joined the ORS as a Grant Development Officer in October 2024. She supports researchers in preparing and submitting grant applications for a variety of funding streams. Fulcher also leads the identification and sharing of targeted funding opportunities with hospital-based researchers and helps new investigators understand research funding procedures. Her research background began at the University of Toronto in 2010, followed by a PhD in Neuroscience at Western University and a postdoctoral fellowship in neuro-oncology. Her combined interests in preclinical and clinical research, writing and achieving a healthier work-life balance led her to this rewarding and intellectually-stimulating role.
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Marina Childs, PhD, is a Grant Development Officer at the ORS. She supports researchers in preparing and submitting grants across diverse opportunities, including team grants and major infrastructure projects. Childs also coordinates the Internal Research Fund (IRF) competition, which offers seed funding to promote innovative research in both basic and clinical areas. Before joining ORS in 2021, she completed a PhD in Organic Chemistry at Western University, earning several scholarships for her imaging molecule work. Passionate about supporting innovation and quality research, Childs draws on her expertise in grant writing and science communication to help advance health research that improves patient care.
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Matthew Maksoud, PhD, is a Grant Development Officer at the ORS. Since joining in 2021, Maksoud has combined his expertise in molecular and cellular neuroscience with over a decade of writing experience to help researchers succeed. He supports grant submissions for competitions like PSI and CIHR and provides guidance on research data management and research security considerations – ensuring projects are both competitive and compliant. He enjoys collaborating with researchers to turn innovative ideas into funded projects.
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Jeksy Manalil, PhD, is a Grant Development Officer at the ORS. She is also the alternate Internal Research Fund (IRF) coordinator for the internal competition that is launched twice every year. She has a background in Biotechnology with a PhD in Biochemistry from India. Manalil joined the ORS in 2024 and was previously a toxicology scientist at a Contract Research Organization that supported premarket product applications to Health Canada. With a strong background in GLP practices and regulatory standards, she brings this expertise in reviewing grant applications and provides feedback that enhances grant competitiveness and research excellence.
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Grants Development Team Tip
All external funding applications submitted through Lawson or LHSCRI need to be reviewed by us (even if no institutional signature is needed). Please reach out early so we can discuss the next steps and support your application. You can reach all of us at Grantsubmission@sjhc.london.on.ca or Grantsubmission@lhsc.on.ca
| | | | LAWSON ASSOCIATION OF FELLOWS AND STUDENTS | | Celebrating science and community spirit at Tribute Dinner | |
St. Joseph Health Care Foundation’s annual Tribute Dinner brings together leaders in health care, research, business and the broader community to celebrate excellence and innovation in health. Held on Oct. 9, this year’s event honoured Ann and Bill Fleming, who are fiercely passionate about St. Joseph’s and Lawson, featured a presentation by science communicator Timothy Caulfield and highlighted the groundbreaking work of Lawson.
Read more about the event here and watch a video highlighting the work happening across Lawson here.
| EQUITY DIVERSITY INCLUSION AND BELONGING (EDIB) | St. Joseph’s has launched the Foundations of EDIB learning program for all staff and physicians. Explore topics like anti-racism, unconscious bias and belonging. Complete at least one module before March 31, 2026, to help build a more inclusive workplace and stronger teams. Find details and start your learning journey. | | We encourage researchers to submit grants, publications and awards for us to showcase. Please provide a one- to two-sentence plain-language description along with the submission. | | |
We recognize and congratulate some of the recent external funding awarded to our researchers:
Sue Peters, Lawson associate scientist and physiotherapist, was awarded funding from the Heart and Stroke Foundation for the study, “Enabling bedside brain measurement to maximize motor outcomes after stroke.” This award provides salary support to the best young researchers in Canada.
This research project seeks to help stroke survivors regain arm movement using a portable neurofeedback device. Because strokes often damage the part of the brain responsible for arm function, many survivors are left with weakness. Our approach uses imagination—asking patients to think about reaching a cup, which activates the brain in ways like actual movement. With our technology, survivors receive real-time visual feedback on their brain activity as they imagine moving. This instant feedback helps them practice and potentially strengthen the affected areas. The funding will support studies to measure how neurofeedback impacts brain function and movement recovery.
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Check out a few examples of the research published in September-October
Coleman KKL, Finger E. (2025). Executive function and the feasibility of clinical trials for frontotemporal dementia. The Lancet Regional Health - Europe.
How do problems with executive functions like planning and decision-making affect participation in clinical trials for frontotemporal dementia? To find out, researchers assessed patients’ decision-making and planning abilities and how these skills influenced clinical trial involvement. They found executive difficulties can limit participation, highlighting the need for tailored clinical trial designs. Clinicians, researchers and families interested in dementia care and representation in research should read this article. #Aging
Sedrak P, Dounaevskaia V, Mancini GBJ, Zieroth S, McKelvie RS, Chiu W, Bewick D, Ducharme A, Mansour S, Lepage S, Pearson GJ, Welsh RC, Udell JA, Connelly KA. (2025). Vaccination in patients with cardiovascular disease: A case-based approach and contemporary review. CJC Open.
How do you best protect heart patients from infections through vaccinations? Researchers reviewed real cases and current evidence to guide vaccine choices for people with cardiovascular disease. They found tailored vaccination strategies can lower risks and improve outcomes. This article is an important read for patients, families and healthcare providers interested in heart health and infection prevention. #EndorinologyMetabolismChronicDiseases
Steele N, Huggins AA, Morey RA, Hussain A, Russell C, …, Lanius R, Densmore M, Theberge J, ... (2025). Image-Based Meta- and Mega-Analysis (IBMMA): A unified framework for large-scale, multi-site, neuroimaging data analysis. NeuroImage.
How can researchers analyze the data from large scale research with multiple sites and complex neuroimaging data sets to better advance our understanding of the brain? Researchers developed a new software tool, Image-Based Meta- & Mega-Analysis (IBMMA) allowing for improved modeling, analysis and detection of findings missed in older software. This breakthrough advances neuroscience and clinical insights. Clinicians, researchers and data scientists should read this article to explore the clinical utility of this tool. #Imaging
Ariba O, Oudshoorn A, Forchuk C, Wathen N, Easton C, Isard R. (2025). Mothering through experiences of homelessness with a particular focus on child separation in high-income countries: A scoping review. Child & Family Social Work.
Do you wonder about how homelessness affects mothers, especially regarding separation from their children in high-income countries? Researchers conducted a scoping review to explore this question. They examined global studies and found that marginalized mothers, those under state surveillance, racialized or facing health and economic challenges, were at higher risk of being separated from their children. The findings highlight urgent policy and care gaps. Healthcare providers, social workers and policymakers interested in mothers experiencing homelessness and how to preserve and reunite families should read this article. #MentalHealth
Hung SH, Ackerley S, Connell LA, Bayley MT, Best KL, Donkers SJ, Dukelow SP, Ezeugwu VE, Milot MH, Peters S, Sakakibara BM, Sheehy L, Yao J, Eng JJ. (2025). Real-world experiences of therapy staff implementing an intensive rehabilitation protocol in Canadian stroke inpatient rehabilitation settings: A multi-site survey study. Physical Therapy.
What are the real-world implementation factors that influence how therapy staff deliver an intensive walking rehabilitation protocol in inpatient stroke rehabilitation settings? Researchers surveyed 47 staff across 12 Canadian rehabilitation units who participated in the Walk ‘n Watch trial. While most staff delivered the protocol successfully, time constraints and device issues were barriers. The findings highlight practical challenges and support future implementation planning. Clinicians, rehab leaders and implementation scientists would find this a valuable resource. #Rehabilitation
Abu Al-Burak S, Butt F, Li X, Garg AX, Hutnik CM, Malvankar-Mehta MS. (2025). Anterior vitrectomy incidence in cataract surgery among experienced surgeons and residents: A systematic review and meta-analysis. European Journal of Ophthalmology.
Does cataract surgery complications differ between experienced surgeons and residents? To find out, the researchers conducted a systematic review and analysis of the literature, focusing on adult in-patients who received cataract surgery from residents and experienced surgeons. Based on limited evidence, they found residents could have a higher rate of anterior vitrectomy, a complication that can affect vision. The findings stress the need for better training and mentorship. Ophthalmology educators, surgical teams and hospital leaders should read this to improve patient care and safety. #SurgicalSpecialties
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Canadian Irma Parhad Award for Excellence to Dr. Manuel Montero-Odasso
Congratulations to Dr. Manuel Montero-Odasso for receiving the prestigious Canadian Irma Parhad Award for Excellence, honouring his outstanding contributions to understanding and treating cognitive disorders. Dr. Montero-Odasso was presented with the award and plaque at the 2025 Canadian Conference on Dementia, held in Calgary. This recognition highlights his dedication to advancing dementia research and care.
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2025 Excellence in Professional Practice Awardees
Congratulations to the Parkwood Consortium Site Implementation Team for earning the Excellence in Professional Practice Team/Group Award. This honour recognizes their exceptional leadership, mentorship and dedication to outstanding patient care. Nominated by their peers and leaders, these outstanding nursing and allied health professionals were recognized at a ceremony on Oct. 1. Help us celebrate their achievement and share the exciting news on LinkedIn, Instagram and Facebook.
| | UPCOMING GRANT COMPETITIONS | | |
Please visit the research funding announcement page to find out more about these funding opportunities:
Notice of upcoming funding opportunities:
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Cardiac Arrest Research Team Grants
Heart & Stroke together with the Canadian Institutes of Health Research Institute of Circulatory and Respiratory Health (CIHR-ICRH) and Brain Canada are collectively committing $5,000,000 over five years to fund the Cardiac Arrest Research Team Grants (CA) funding opportunity.
This funding opportunity is coordinated with the American Heart Association (AHA) Cardiac Arrest funding opportunity to encourage collaboration and partnership of those funded to leverage, amplify and coordinate research activities where appropriate.
The registration deadline is Dec. 16 at 3 pm ET. Eligible registrants will be notified and invited to submit a full application, which will be due by March 17, 2026.
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Funding opportunities for trainees:
These funding opportunities support the next generation of researchers. Trainees and researchers should confirm internal deadlines and application procedures with their institutions (i.e., Western University, Lawson Research Institute, etc.).
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Each year, the Canadian Public Health Association (CPHA) recognizes individuals, groups and organizations that have made a significant contribution in public health. CPHA is now accepting nominations for the following awards and honours:
- R.D. Defries Award
- Honorary Life Membership
- Certificate of Merit
- Ron Draper Public Health Promotion Award
- National Public Health Hero Award
Nominations should be submitted following the guidelines and forwarded to the CPHA Awards Committee for review no later than January 6, 2026.
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CIHR: 2026 IHSPR-CAHSPR Article of the Year Award
In continued partnership, the Canadian Institutes of Health Research - Institute of Health Services and Policy Research (IHSPR) and Canadian Association for Health Services and Policy Research (CAHSPR) are pleased to launch the annual Article of the Year competition. The Article of the Year competition aims to recognize ground-breaking health services and policy research (HSPR) published in the prior year in a peer-reviewed journal that has significantly contributed to the field of HSPR. The recipient is honoured with an award of $10,000, a Certificate of Excellence presented at the annual CAHSPR conference and the opportunity to orally present their article at a CAHSPR HSPR Talks webinar as well as at a lunchtime session at the CAHSPR conference. Applications are open until January 15, 2026. Learn more and submit your article.
CIHR: 2026 IHSPR-CAHSPR Health Services and Policy Research Impact Award
The Canadian Institutes of Health Research - Institute of Health Services and Policy Research (IHSPR) and Canadian Association for Health Services and Policy Research (CAHSPR) are pleased to launch the inaugural Health Services and Policy Research Impact Award competition.
The HSPR Impact Award recognizes HSPR that has made an impact by demonstrably contributing to the transformation of health systems, improving people’s lives, or generating social or economic benefits. This award celebrates research that has moved beyond publication to achieve real-world impact - such as influencing policy, improving service delivery, advancing health equity or contributing to economic and social prosperity.
The recipient is honoured with an award of $10,000, a Certificate of Excellence presented at the annual CAHSPR conference and the opportunity to orally present their article at a CAHSPR HSPR Talks webinar as well as at a lunchtime session at the CAHSPR conference. Applications are open until January 15, 2026. Read more about the award and how to apply.
| | Register for DocTalks with Dr. Kristin Clemens | | | | An engaging in-person DocTalks event is taking place on Dec. 3, with Dr. Kristin Clemens at St. Joseph’s Hospital. Dr. Clemens will explore the future of diabetes, metabolic and chronic disease care and dive into how we can better serve patients by addressing systemic challenges and applying real-world evidence. Registration is now open. | | | 268 Grosvenor Street | London, ON N6A 4V2 CA | | Lawson Research Institute, the health innovation arm of St. Joseph's Health Care London, is committed to making discoveries that improve lives. Every day, Lawson scientists work to translate their ideas into innovations that improve patient care. Lawson LEADS health research. Find us online at LawsonResearch.ca and on social media @stjosephslondon | | Did someone forward this email to you? You can subscribe here to get Lawson LEADS newsletter delivered directly to your inbox. Missed a previous newsletter? Visit the Lawson News and Events page. | | | | |