Can't see the full newsletter? Please accept images and add Lawson LEADS (lawsonresearch-sjhc.london.on.ca@shared1.ccsend.com) to your safe list. | | Proudly introducing Lawson Research Institute's 2025-2030 Strategic Plan | | Lawson Research Institute (Lawson) at St. Joseph’s Health Care London has unveiled its 2025–2030 strategic plan, a visionary roadmap for advancing health research. Rooted in curiosity and discovery, the plan focuses on purposeful growth, new infrastructure and a culture that attracts top talent. It reflects Lawson’s commitment to transforming health systems and improving patient care through innovation. Shaped by the voices of researchers and partners, this strategy strengthens Lawson’s role as a leader in discovery-driven, patient-focused research, locally and globally. Explore Lawson’s new five-year strategic plan. | | Celebrating discovery and compassion: 40 years of transforming cognitive brain care for families | | For four decades, Dr. Michael Borrie has been a guiding light for families facing Alzheimer’s disease, dementia and related conditions at Lawson Research Institute and St. Joseph’s Health Care London. As Medical Director of the Aging Brain and Memory Clinic, his pioneering research and heartfelt care have helped countless patients, and now, even the grandchildren of his earliest patients. Dr. Borrie’s commitment to early detection, innovative studies and better treatments has made St. Joseph’s a national leader in dementia care. His legacy is woven into the fabric of Lawson - one of hope, compassion and discovery for generations. Click here to read or watch to discover more about Dr. Borrie’s incredible career and the difference he’s made for families. | | Walking toward recovery: A new stroke rehab breakthrough | | |
Sue Peters, PhD is leading a national effort to improve stroke recovery through movement. Her latest research—published in The Lancet Neurology—shows how a structured walking program called Walk ‘n Watch can help stroke patients regain mobility faster during inpatient rehabilitation. The protocol encourages patients to engage in 30 minutes of progressive, heart-rate-monitored walking activities five days a week, guided by physical therapists. Compared to standard care, patients in the Walk ‘n Watch group walked significantly farther after just four weeks, with no serious safety concerns. Dr. Peters' work demonstrates that with the right support and structure, stroke survivors can take meaningful steps toward independence. Read more about the study and its impact in The Lancet Neurology.
| | Teamwork in primary care keeps seniors safe and thriving | | |
Dr. Manuel Montero-Odasso's groundbreaking research, featured in the Journal of the American Medical Association, shows how teamwork in primary care can help prevent falls and keep seniors thriving. His studies reveal that a blend of regular physical activity, brain-challenging exercises and healthy daily habits can lower the risk of both falls and memory problems for older adults. Older adults are encouraged to stay active through exercises, engage in memory games and maintain good nutrition and sleep routines to boost both mobility and brain health. By linking together healthcare providers, patients and caregivers, Dr. Montero-Odasso shows that “it takes a village” to help seniors stay safe and independent. Read more about these practical tips and the full research by clicking the link to the published article.
| | |
Access - Expo - Accessibility empowers everyone to live fully
Parkwood Institute hosted the Access Expo on September 11, spotlighting the latest in accessible technology and adaptive devices. Researchers from Research 2 Practice and the Gray Centre for Mobility and Activity played a key role, sharing innovations that help people overcome barriers and improve daily life. The event featured hands-on demos and lively discussions, showing how research drives real-world solutions. Want to see more? View photos on St. Joseph’s intranet.
| | |
In August 2025, Lawson Research Institute was actively conducting 903 clinical research studies, underscoring its dedication to advancing patient-centered medical innovation.
Visit Lawson’s Webpage to discover more about our clinical trials and how to get involved.
| | How clinical trials shape tomorrow's medicine: Advancing patient care one discovery at a time | | |
Clinical trials are a vital part of how new treatments, devices and care strategies are discovered, tested and improved for patients. Every medication, vaccine or therapy used in hospitals today was once carefully evaluated through clinical research. At their core, clinical trials help answer important questions: Does this treatment work? Is it safe? Can it improve quality of life?
Clinical trials at Lawson Research Institute
Hospital-based research teams at Lawson advance health care by conducting clinical trials that deliver innovation to patients. Partnering with medical professionals, researchers and volunteers, these studies follow strict ethical and safety standards set by research ethics boards. In September, Lawson supported 903 clinical research studies, underscoring the dedication to advancing patient-centered medical innovations.
Understanding phases of clinical trials
Clinical trial research generally unfolds in phases. Phase I studies test a new treatment in a small group to assess safety and dosage. Phase II expands to more participants, focusing on effectiveness and side effects. Phase III involves large groups, confirming benefits and monitoring reactions compared with standard care. After approval, Phase IV studies continue to track long-term safety and real-world performance.
| |
| |
RESEARCH TIP
The Institute for Clinical Evaluative Sciences (ICES) is an Ontario-wide non-profit partnership in Ontario focused on health research and analysis. ICES uses data to evaluate health care services, improving policies and patient outcomes in the province. To learn more about ICES, how you can get involved, or the work they have been doing visit: ICES Western | St. Joseph's Health Care London.
Clinical research support services are also available at a fee-per-service level through LHSC’s Clinical Research Support Services. Contact Sue Tereschyn at sue.tereschyn@lhsc.on.ca
| | | | Office of Research Services | | The Contracts team in the Office of Research Services (ORS) helps support both the Lawson and London Health Sciences Centre Research Institute (LHSCRI) by reviewing, negotiating and finalizing research agreements to ensure compliance and safeguard the institution’s interests. Working closely with researchers and partners, the team streamlines the contracting process so that research projects can begin efficiently and on schedule. | | |
Katrina Haasen is Manager of the Research Approvals and Contracts team at the ORS. With over 15 years in research administration—including roles at the Multiple Sclerosis Society of Canada and the Hospital for Sick Children—she joined Lawson in 2017, progressing from Contracts Officer to her current leadership role. Haasen oversees daily operations, drives service improvements and collaborates with internal and external stakeholders. She holds an HBSc. from Western University, an MSc. in Cell & Systems Biology from the University of Toronto and a professional certificate in Accounting/Finance from Toronto Metropolitan University. Outside of work, she enjoys collecting Mid-Century Modern and Scandinavian glass and walking her dachshund, Penny.
| | |
Lawrence Burns, JD, is a Senior Contract Officer at the ORS. A licensed lawyer with a PhD in Philosophy, Burns joined ORS in 2022 after serving as a Staff Lawyer at Neighbourhood Legal Services (London and Middlesex). He brings a background in health ethics and policy and previously volunteered with Western’s Health Sciences Research Ethics Board. In his current role, he drafts, reviews and negotiates research contracts, while also supporting the Contracts Officers in ensuring policy compliance, managing risk and advancing institutional and investigator interests.
| |
Catherine Hann is a Contract Officer in the ORS with nearly a decade of contract management experience. Licensed by the Law Society of Ontario, she holds diplomas in Law Clerk and Paralegal Honours. Since joining Lawson in 2017, she has managed CDAs, DSAs and research contract execution. Promoted in 2021, she now oversees clinical trial, grant and funding agreements. With a background in paralegal and office management, Hann is committed to supporting researchers through risk assessment, compliance and strong client service.
| |
Lisa Rigg, M.Cl.Sc., BHSc, is a Contract Officer at the ORS, where she facilitates the drafting, review and negotiation of research contracts with partners worldwide, ensuring legal and regulatory compliance. Before joining ORS, she supported governance, policy and project implementation at Western University and Ontario Health. Rigg holds degrees in Health Sciences and Clinical Sciences from Western, along with certificates in leadership, HR, project management and quality improvement. She is passionate about advancing health systems and supporting research that improves patient care and quality of life.
| |
Sarah Periard, DMA, is a Contract Officer at the ORS, where she manages the negotiation, drafting and administration of research agreements to ensure legal and regulatory compliance. She brings extensive experience from leadership roles at Western University in academic administration, finance, governance and event coordination. Periard holds a Doctor of Musical Arts from the University of Toronto and a Master of Music from Western University. She also holds multiple professional certificates and the Chartered Manager (CIM) designation, reflecting her strengths in leadership, business and project management.
| |
Uzodinma Emeka, LL.B, is a Contract Officer at the ORS, with over a decade of experience in contract negotiation, administration and compliance. He specializes in drafting, reviewing and executing a wide range of research agreements, ensuring alignment with regulatory, ethical and institutional standards. Emeka collaborates with investigators, sponsors and partners to manage risk and support research innovation through efficient, compliant contract solutions.
| |
Johana McCallum is a Contract Associate at the ORS and a Licensed Paralegal with a background in civil litigation and personal injury. She drafts, reviews, negotiates and processes research contracts—including CDAs, DSAs and MTAs—while supporting risk management and stakeholder collaboration. McCallum also provides backup administrative support to the Contracts Team and is fluent in Spanish.
| |
Jessica Grant, is the Team Assistant at the ORS, providing vital administrative and organizational support to staff and researchers. With over a decade of healthcare administration experience and a diploma in Medical Office Administration, she manages the Contracts Team triage inbox, DocuSign processes and daily operations. Bilingual in English and Arabic, Grant helps ensure smooth, responsive service for Lawson’s diverse research community.
| | LAWSON ASSOCIATION OF FELLOWS AND STUDENTS | | |
The Lawson Association of Fellows and Students (LAFS) is a trainee-led organization representing a diverse community of more than 100 post-doctoral, graduate, professional and undergraduate trainees from various research and professional disciplines. Our mission is to foster educational, social and career development opportunities that empower trainees to engage with the London research community.
LAFS promotes research excellence by fostering interdisciplinary collaboration, personal development and knowledge exchange through diverse academic, social and career-oriented events. LAFS also works closely with Lawson leaders to provide input on strategic direction and ensure emerging researchers’ perspectives are reflected in future decisions.
You can stay up to date with LAFS through our mailing list, follow us on Instagram @lafs_london or email us at lafs@lawsonresearch.com
| | We encourage researchers to submit grants, publications and awards for us to showcase. Please provide a one- to two-sentence plain-language description along with the submission. | | |
We recognize and congratulate some of the recent external funding awarded to our researchers:
Dr Justin Hicks was awarded funding from the Cancer Research Society for the study "Investigating the role of L-glucose as a therapy and [18F]fluoro-deoxy-L-glucose as a diagnostic for glioblastoma", $134,930 over 2 years.
Researchers are exploring a new way to treat and diagnose glioblastoma, a type of brain cancer, by using a special form of sugar called L-glucose. To better understand how this special type of sugar works in brain tumors, researchers have developed a way to track it inside the body. They have discovered that it goes directly into cancer cells, and not healthy cells which may be used as a way to destroy cancer cells. This research funding will be used to test and image how well L-glucose can destroy cancer cells within small human tissue samples called organoids. If successful, this approach could lead to new treatments.
| | |
Check out a few examples of the research published in August-September
Budhram A, Rutledge AC, Sangam K, Pasternak S, Finger E, Borrie MJ, Bhangu J. Positive predictive value of CSF biomarker testing for a clinical diagnosis of Alzheimer's disease. Canadian Journal of Neurological Sciences.
How reliable are spinal fluid tests for diagnosing Alzheimer’s disease? This study explored how well a cerebrospinal fluid (CSF) biomarker test predicts Alzheimer’s in patients with memory problems. The team used a Health Canada-approved test to measure proteins linked to Alzheimer’s in spinal fluid samples to learn if a positive test result means a patient has Alzheimer’s. They found that while the test is highly specific, not every positive result confirms the disease. This is important because it helps doctors and patients understand the strengths and limitations of some biomarker testing and the need for a thorough evaluation of patients. Anyone interested in Alzheimer’s diagnosis should read this article to learn about these tests and how they fit into clinical care. #Aging
Varghese A, Kang Y, Cowan A, Holden R, Wald R, Clemens KK. Monitoring, control, and clinical outcomes associated with chronic kidney disease-mineral bone disorder: A population-based cohort study in Ontario, Canada. Kidney Medicine.
How does chronic kidney disease affect bone health and patient outcomes? This Ontario-based study looked at people with chronic kidney disease (CKD) to understand how well their mineral and bone-density was being monitored and managed. Using health records from thousands of patients, they found that many people were not getting regular monitoring or optimal treatment – which can lead to complications like bone fractures and heart problems. The study highlights the need for better care and follow-up for patients to prevent serious health issues. Patients, families and health care providers who want to learn how regular testing and treatment can improve quality of life and reduce risks for those living with CKD will find this an important research article to read. #EndorinologyMetabolismChronicDiseases
Dassanayake P, Diksha D, Varela-Mattatall G, Sun Q, Donnelly SC, Suchy M, Barolome D, Furlong S, Deans L, Biernaski H, Huston Y, Thompson RT, Burton JP, Moran G, Gelman N, Prato FS, Kovacs MS, Thiessen JD, Goldhawk DE, Schellenberg J, Fox MS. Biodistribution and dosimetry of 89Zirconium-labeled microbiota transplants in the pig gut. Medical Physics.
Ever wonder what happens to probiotics after you take them? Lawson researchers have developed an innovative way to watch the movement of transplanted bacteria in the gut using PET/MRI. This technique lets scientists see exactly where the bacteria go and measure how much radiation is involved. Why does this matter? By following the journey of these bacteria, researchers can better understand how probiotic therapies work and how effective they are. This breakthrough could help doctors develop personalized treatments and determine the effectiveness of probiotic therapies. This article provides valuable information on gut health for patients, healthcare professionals and researchers. #Imaging
Soares V, Deda E, Houle SA, St. Cyr K, Forchuk CA, Plouffe RA, Liu JJW, Cramm H, Nazarov A, Richardson JD. (2025). Challenges and facilitators for mental health care for operational stress injuries in the military: A qualitative study. Journal of Military, Veteran and Family Health.
Canadian Veterans often face unique challenges in getting mental health care for conditions related to their service. This study interviewed Veterans to better understand what helped or hindered their treatment journey. Six key themes were identified, including the impact of COVID-19. Veterans described barriers such as stigma and navigating complex health systems, as well as the importance of timely access to care, culturally informed treatment and strong social networks. By shaping more effective care pathways, these insights may help ensure that more Veterans access and benefit from treatment. #MentalHealth
Pieruccini-Faria F, Son S, Zou G, Almeida QJ, Middleton LE, Bray NW, Lussier M, Shoemaker JK, Speechley M, Liu-Ambrose T, Burhan AM, Camicioli R, Li KZH, Fraser S, Berryman N, Bherer L, Montero-Odasso M. Synergistic effects of exercise, cognitive training and vitamin D on gait performance and falls in mild cognitive impairment—secondary outcomes from the SYNERGIC trial. Age and Ageing.
Can exercise and brain training help prevent falls in older adults with memory problems? This article examined the effects of combination interventions on gait performance and falls in individuals with mild cognitive impairment. It found that a combination of aerobic-resistance exercise was able to significantly improve gait speed and reduce falls, particularly in combination with cognitive training. Seniors, caregivers and healthcare professionals should read this article to learn practical ways to reduce fall risk and support healthy aging. #Rehabilitation
Pejhan S, Barra L, Basharat P, Allen LH, Bursztyn LLCD, Proulx A, Chen RY, Smith M, Hackett M, Hammond R. (2025). Clinical relevance and prognostic significance of isolated angiitis of the vasa vasorum in temporal artery biopsies. Canadian Journal of Neurological Sciences.
Can a rare blood vessel condition predict future health risks? Researchers explored isolated angiitis of the vasa vasorum found in temporal artery biopsies. By reviewing patient samples, they discovered this condition may have important implications for diagnosis and prognosis. Their findings help doctors better understand and manage patients with unexplained symptoms. Anyone interested in vascular health or autoimmune diseases should read this article to learn more about its impact. #SurgicalSpecialties
| | |
Appointment to Ontario Hospital Association Board of Directors
Congratulations to President and CEO Roy Butler on his appointment to the Ontario Hospital Association Board of Directors. We look forward to witnessing his exceptional leadership drive meaningful change across our health care system. Share this on LinkedIn.
| | |
2025 Innovative Practice Researcher Award
Amanda McIntyre, PhD, RN, received the "Innovative Practice Researcher Award" from the International Association of Rehabilitation Nurses in September 2025. This award honors an individual who has contributed significantly through research or evidence-based practice aimed at advancing rehabilitation nursing.
| | |
Pharmacy resident wins third place at the Southwestern Ontario Pharmacy Resident Research Project Night
Meet Celeste Giovanatti, St. Joseph’s second pharmacy resident, whose research is changing how we think about urgent care. During her year at St. Joseph's, her research project found that many visits to urgent care for minor ailments could potentially have been handled by a community pharmacist instead. Through this research, she noticed a gap in the public’s knowledge about pharmacists and their role in the healthcare system. Celeste’s work placed third at the Southwestern Ontario Pharmacy Resident Research Project Night. To read more about her research head to St. Joseph’s on Instagram.
| | UPCOMING GRANT COMPETITIONS | | |
AHSC AFP Innovation Fund call for proposals Fall 2025
Closing date: October 31, 2025
The AMOSO Innovation Fund Fall 2025 Call for Proposals is now open. Submit your proposals by October 31, 2025, 11:59 PM to amoso@lhsc.on.ca.
The Innovation Fund is intended to support the development of new and innovative practices in health care delivery (both quality initiatives and research projects), and to support leadership and the dissemination of knowledge across the healthcare system.
IMPORTANT NOTICE:
The Provincial Proposal Forms and Guidelines for the 2025-26 funding competition have changed. Please refer to the AMOSO website for application forms, instructions/guidelines and information on the adjudication process.
Ensure approval from the Financial Management Committee (FMC) for the Lead Project Sponsor’s AFP Practice Plan before submission. All required documents must be completed and submitted in Microsoft Word format.
To access the AMOSO website use the following generic log-in information.
Username: amoso Password: afpfunding
| | |
Please visit the research funding announcement page to find out more about these funding opportunities:
Notice of upcoming funding opportunities:
| | |
Funding opportunities for trainees:
These funding opportunities support the next generation of researchers. Trainees and researchers should confirm internal deadlines and application procedures with their institutions (i.e., Western University, Lawson Research Institute, etc.).
| | |
Medical Advisory Committee (MAC) award nominations
Do you know a hospital or a credentialed professional staff member who has gone above and beyond the call of duty? Nominations for this year’s MAC awards are due Oct. 31.
Award criteria and nomination forms are available on the MAC awards intranet page.
| | Spiritual Care and St. Joseph’s Health Care Society are hosting a special event on Oct. 23, focusing on ‘Exploring Sacred Moments: An Interdisciplinary Dialogue. Hear interdisciplinary perspectives on sacred moments from Karen Perkin, Stephen Yeo and Dr. Serena Wong. A light lunch will be served. Register to join in-person or virtually! | | New date for DocTalks with Dr. Serena Wong | | |
The new date for our in-person DocTalks event with Dr. Serena Wong is Oct. 29. Join us for an insightful session about the role of sacred moments in healing from trauma and loneliness. Mark your calendars and don’t miss this opportunity to engage with a leading voice in the field. Sign up today.. The DocTalks Podcast, brought to you in partnership with St. Joseph's Health Care Foundation and produced by The Pod Cabin and Emily Mackey, offers valuable insights and expert advice.
| | Canadian conference in Organoid Research | | The Canadian Organoid Conference (CANCOR-CCRO) will be hosted in London on Nov. 5 and 6. This event brings together researchers, clinicians, trainees and industry partners from across the country to share the latest advancements in organoid technology. This year's plenary speaker is Dr. Hans Clevers from Utrecht University. Contact Chris.Pin@lhsc.on.ca for more information. Learn more. | | | 268 Grosvenor Street | London, ON N6A 4V2 CA | | Lawson Research Institute, the health innovation arm of St. Joseph's Health Care London, is committed to making discoveries that improve lives. Every day, Lawson scientists work to translate their ideas into innovations that improve patient care. Lawson LEADS health research. Find us online at LawsonResearch.ca and on social media @stjosephslondon | | Did someone forward this email to you? You can subscribe here to get Lawson LEADS newsletter delivered directly to your inbox. Missed a previous newsletter? Visit the Lawson News and Events page. | | | | |
