An article in
The New York Times features the latest research from HSCI principal faculty member Pier Paolo Pandolfi, which
links dietary fat with aggressive prostate cancer. In mice with a certain genetic background that predisposed them to prostate cancer, tumors spread beyond the prostate only when the animals were fed a high-fat diet. Motivated by these results, Pandolfi is planning a clinical trial to test whether an obesity drug which blocks fat production can treat prostate cancer.
recent study led by principal faculty member Fernando Camargo, HSCI researchers used genetic barcodes to label blood system stem cells in mice. After tagging the cells, the researchers tracked them during the process of natural blood production and characterized how the stem cells differentiate into specialized blood cells.
The results contribute to the field's understanding of blood cell biology and could inform the development of gene therapy technologies.