LDA NEWS & UPDATES 

July 31, 2023

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LDA-Columbia University CME Lyme & TBD Conference

 

Virtual, October 13,14, 2023

 

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Comparison of Lyme and PTLDS Claims in the U.S.

Study Examines Billions of Billing and Rx Records

eBioMedicine (Chung M.K., et al.) 04.2023, published “Systematic comparisons between Lyme disease and post-treatment Lyme disease syndrome in the U.S. with administrative claims data.” The study used a large nationwide dataset, consisting of billions of billing and prescription records from 2008 to 2016, to identify specific characteristics of PTLDS that could provide diagnostic values and causes. Read more.

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Paralytic Neurologic TBD Treated with Combo Therapy

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Study Showed Positive Results Although Limited

Antibiotics (Trouillas P., et al.) 06.07.2023, published “Complete Remission in Paralytic Late Tick-Borne Neurological Disease Comprising Mixed Involvement of Borrelia, Babesia, Anaplasma, and Bartonella: Use of Long-Term Treatments with Antibiotics and Antiparasitics in a Series of 10 Cases.” The study was designed to demonstrate the eligibility for long-term combined antibiotic/antiparasitic treatments in cases of severe neurological motor deficits caused by late tick-borne disease due to mixed microorganisms. Read more.

New Alpha-Gal Syndrome MMWR Publications

Read the Geographic Distribution report.


Read the Health Care Provider Knowledge report

A Free CME/CE Training Will Be Offered

The CDC’s Morbidity and Mortality Weekly Report 7.28.23 published two articles on alpha-gal syndrome (AGS), also known as "red meat allergy." AGS is an emerging tick-bite associated allergic condition that causes a potentially life-threatening hypersensitivity to an oligosaccharide existing in most mammalian meat and meat-derived products. The reports highlight that AGS is of growing concern for public health, however, many providers are unaware of the condition or how to diagnose and manage it. Read more.

Why Lyme Gets Misdiagnosed as Depression, Bipolar, Etc.

Take Steps to Narrow Down the Possibilities

Everyday Health published “Why Lyme Disease Gets Misdiagnosed as Depression, Bipolar, and More” on 7.24.2023, written by Katie Camero, and medically reviewed by Seth Gillihan, PhD. and Sheila Statlender, PhD. The article describes Lyme disease as “the great imitator” because symptoms mimic many other physical and mental conditions and therefore can be often misdiagnosed. Read more.

Read the article.

NIH Funding Post Treatment Lyme Research for 5 Projects

Read the press release.

Narrowing Down on PTLDS

National Institutes of Health (NIH), 7.21.23, announced they have awarded approximately $3.2 million dollars in funding for this first year of research focused on possible causes of persistent Post Treatment Lyme Disease Symptoms (PTLDS). This is year one of a 5-year award in support of this work. Read more.

Fighting Adrenal Fatigue

Addressing the Root Cause

The Peoples Pharmacy, 7.18.2023, produced Podcast Show 1347: “How to Combat Adrenal Fatigue,” with guest, Izabella Wentz, PharmD, FASCP. Izabella is an internationally recognized thyroid specialist and pharmacist who was diagnosed with Hashimoto’s thyroiditis in 2009. She has since dedicated her career to addressing the root causes of autoimmune thyroid disease. Read more.

Listen to the podcast.

Results of Lyme Vaccine Phase 1 Study

Read the study.

Safe and Immunogenic

The Lancet (Bézay, N., et al.) 07.04.2023, published “Safety and immunogenicity of a novel multivalent OspA-based vaccine candidate against Lyme borreliosis: a randomised, phase 1 study in healthy adults.” This study investigates a Lyme borreliosis vaccine candidate (VLA15) to prevent an infection with pathogenic Borrelia spp which is prevalent in North America. Read more.

Bartonella in Flies, Lone Star Ticks and Human with Lyme

Study Leads to More Discoveries

Vector-Borne and Zoonotic Diseases (Clark K. L., et al.) 7.10.2023, published “Detection of Bartonella DNA in Yellow Flies, Lone Star Ticks, and a Human Patient with Concurrent Evidence of Borrelia burgdorferi Infection in Northeast Florida, USA.” This study investigated cases of Bartonella species and Borrelia burgdorferi sensu lato (Bbsl) in yellow flies in northeast Florida that led to the discovery of cases of Bartonella and Bbsl in lone star ticks and one human patient. Read more.

Bartonella henselae

Read the study.

Environmental Surveillance of SARS-CoV-2 Aerosols

Real-Time Virus Detection

Nature Communications (Puthussery J. V., et al.) 07.10.2023, published “Real-Time Environmental Surveillance of SARS-CoV-2 Aerosols.” The study points out the unavailability of quick infection protocols for the public and focuses on the use of virus aerosol detection methods used to test air for the presence of SARS-CoV-2 which is spread through droplets in the air originating from coughing, sneezing, breathing, and speaking. Read more.

Coronavirus ultrastructural morphology. Credit: Alissa Eckert, MS; Dan Higgins, MAMS


Read the study.

Deer Tick Nymphs & Repellents

Read the study.

Many Variables to Consider

Parasites Vectors (Burtis, J.C., et al.) 7.10.23, published “Comparison of in vitro and in vivo repellency bioassay methods for Ixodes scapularis nymphs.” In vitro bioassay methods are most commonly used for the testing of new potential unregistered active ingredients. This study aimed to compare both in vitro (use of artificial containers) and in vivo (human subject) methods. Read more.

Fibromyalgia & Borrelia Association

Novel Study Uncovers Possibility

Current Rheumatoligical Review (Puri, B.K., et al.) 6.5.23, published “Antinuclear Antibody Seropositivity in Fibromyalgia Associated with Borrelia-specific T Lymphocytes.” Researchers tested the hypothesis that fibromyalgia patients who are ANA positive will show evidence of Borrelia-specific T lymphocyte activity more than those who are seronegative. The study uncovered a small number of cases showing that infection by genus Borrelia may be associated with antinuclear antibodies (ANA) in fibromyalgia patients. Read more.

Read the study.

Managing TBD with Natural Bioactive Nutraceuticals

Various tick species at different life stage. Credit J. Occi, PhD

Read the study.

Exploring the Use of Dietary Supplements

Microorganisms (Shor S. M., et al.) 07.05.2023, published “The Use of Natural Bioactive Nutraceuticals in the Management of Tick-Borne Illnesses.” The study explored the use of bioactive phytochemicals, nutraceuticals, and micronutrients (dietary supplements) that could help with the management of persistent cases of Lyme disease and other tick-borne diseases (Borrelia burgdorferiBabesia, and Bartonella). Read more.

MA Crowd-Funded Tick Testing & Anaplasma & Babesia

Expanding Knowledge on Tick Testing Surveillance

Microorganisms (Siegel, E.L., et al.) 5.27.23, published “Human-Biting Ixodes scapularis Submissions to a Crowd-Funded Tick Testing Program Correlate with the Incidence of Rare Tick-Borne Disease: A Seven-Year Retrospective Study of Anaplasmosis and Babesiosis in Massachusetts.” The study sought to expand upon prior passive Ixodes scapularis tick testing surveillance measures by including two rare tick-borne diseases, babesiosis and anaplasmosis. Read more.

Read the study.

Anaplasma Phagocytophilum Case Report & Lit Review

Reconsidering Nonspecific Symptoms

Microorganisms (Dumic E., et al.) 06.02.2023, published “Anaplasma phagocytophilum Community-Acquired Pneumonia: Case Report and Literature Review.” The report focuses on an immunocompetent patient that presented non-specific symptoms including a fever, cough, and shortness of breath. An X-ray and CT scan showed signs of pneumonia. The patient was tested for both common and uncommon causes and the results showed a positive result for anaplasmosis. Read more.

Read the study.

Static Electricity Attracts Ticks Onto Hosts

Deer Tick Questing

Credit: J. Occi, PhD

Read the study.

Another Look at Tick Questing Behavior

Current Biology Journal (England S.J., et al.) 06.30.2023, published “Static electricity passively attracts ticks onto hosts.” The study's goal was to prove the hypothesis that ticks are passively attracted to mammals, birds, and reptiles through electrostatic forces from the animals. Most land animals generate “electric forces that interact with other charges in their environment.” The study hypothesizes that ticks are incapable of jumping and therefore are pulled by the animal’s electric fields onto the animal. Read more.

BREAKING LYME RESEARCH NEWS! 

Medication Used to Stop Cancer May Be Effective for Lyme Disease 

Pathogens, Adam Lynch, et al., July 22, 2023. Read article.



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