NEW Featured Clinical Trials

*MBCBrainMets.org is currently featuring clinical trials led by our

Medical Advisory Board. Not every clinical trial is a good match for every patient, but there are many ongoing and new clinical trials for patients living with MBC brain mets and leptomeningeal disease. We hope you find it a helpful way to learn about one of the trials currently recruiting patients.

NRG BN 014 RADIATE-LM Clinical Trial

Find a Trial that's Right for you

Below you will find the first and only clinical trial search tool designed specifically for patients with brain metastasis or leptomeningeal disease from breast cancer. To view examples of ongoing clinical trials for Stage IV MBC brain metastasis or leptomeningeal disease, visit our Find a Clinical Trial page.

NEW Educational Webinar

Research Updates and Advances in Brain Metastases

NEW Research Articles

We are thrilled to announce that we have new research articles available for you to explore. Stay informed and up-to-date with the latest findings.

Phase II trial of brain MRI surveillance in stage IV breast cancer

Current guidelines do not recommend routine brain MRI screening for patients with stage IV breast cancer who have no neurological symptoms. This study aimed to determine how often brain metastases are found in these patients through early screening.

Researchers conducted brain MRIs on 101 patients with different breast cancer subtypes (HR+/HER2-, HER2+, and triple-negative). The initial scans detected brain metastases in 14% of patients. A follow-up MRI at six months showed an increase, with about 25% of patients across all subtypes developing brain metastases.

These findings suggest that routine brain MRI screening may help detect metastases earlier in certain patients. Further research is needed to refine screening recommendations.

Would you like to Share your Story?

We want to hear from YOU!

We have two different opportunities for you to share your story: blog and video. Your patient voice and story matters. Sharing your story can provide hope and inspiration to others diagnosed or undergoing treatment.

Patient Blog

Would you like to write about your story? For questions or to submit your blog, please email mbcbrainmets@gmail.com for guidance.

No patient should have to go through MBC brain metastasis alone. Read some of our patient stories which are vulnerable, honest, and poignant.

Patient Video

If you are interested in creating a video, please email mbcbrainmets@gmail.com for guidance.

Take a look at the videos from patients living with brain metastasis who share their experiences of receiving a brain metastasis diagnosis, participating in a clinical trial, and undergoing treatments like a craniotomy, whole brain radiation, and others.

This is a Zoom Support Group meeting twice a month from 3:00-4:30 ET. The group is for women of all ages who have been diagnosed with brain metastases or leptomeningeal disease from breast cancer. Please join us to find hope, support and information from others living with this disease. 

Registration is required for new participants.