Deconditioning Does Not Explain Orthostatic Intolerance in ME and CFS
"This study shows that in ME and CFS patients' orthostatic intolerance is not caused by deconditioning as defined on cardiopulmonary exercise testing. An abnormal high decline in cerebral blood flow during orthostatic stress was present in all ME/CFS patients regardless of their %peak VO2 results on cardiopulmonary exercise testing."
Patient selection: "Based on their symptoms, we established the diagnosis of chronic fatigue syndrome (CFS) according to the Fukuda Criteria and myalgic encephalomyelitis (ME) according to the international ME criteria. In all patients, alternative diagnoses which could explain the fatigue and other symptoms were ruled out."
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