MPTs: Articles from the Field

MPTs: Articles

from the Field

Issue #52 - 15 August 2018

Greetings,

The field of multipurpose prevention technologies (MPTs) is steadily evolving and expanding. Below are links to recent publications, media articles, and other resources relevant to MPTs in order to keep you informed. Note that contents are neither endorsed by nor necessarily represent the views of the IMPT, and that due to publication copyright and permissions restrictions, full-text versions of resources may not be publicly available.

If you have a resource to include in our next issue, please send to Kathreen Daria . Previous issues are available in our archives and other MPT-related materials are accessible in our resource center .

Best,

Secretariat Staff

Journal Articles

A pilot study on the functional performance and acceptability of an innovative female condom (Wondaleaf®) in Malaysia . Ting, R.S., Wong, E. & Tnay, J.K. (2018, 24 January). Open Access Journal of Contraception. doi: 10.2147/OAJC.S152505

An update of the recombinant protein expression systems of Cyanovirin-N and challenges of preclinical development . Lotfi, H., Sheervalilou, R., & Zarghami, N. (2018). BioImpacts. dx.doi.org/10.15171%2Fbi.2018.16

Contraceptive rings promote vaginal lactobacilli in a high bacterial vaginosis prevalence population: A randomised, open-label longitudinal study in Rwandan women. Crucitti et al. (2018, 23 July). PLOS One. doi.org/10.1371/journal.pone.0201003

Development of a vaginal fast-dissolving insert combining Griffithsin and Carrageenan for potential use against sexually transmitted infections. Lal et al. (2018, 11 June). Journal of Pharmaceutical Sciences. doi.org/10.1016/j.xphs.2018.06.002

Effectiveness of female condom in preventing HIV and sexually transmitted infections: a systematic review protocol . Mome et al. (2018, 7 August). BMJ Journals. dx.doi.org/10.1136/bmjopen-2018-023055

End-users' product preference across three multipurpose prevention technology delivery forms: Baseline results from young women in Kenya and South Africa. Weinrib et al. (2018). AIDS and Behavior. doi.org/10.1007/s10461-017-1911-6

Interest in multipurpose prevention technologies to prevent HIV/STIs and unintended pregnancy among young women in the United States. Hynes et al. (2018). Science Direct. doi.org/10.1016/j.contraception.2017.10.006

Multipurpose prevention technologies: A global sexual and reproductive health priority. Guillamo-Ramos et al. (2018). Journal of the Association of Nurses in AIDS Care. doi.org/10.1016/j.jana.2017.06.003

Randomized, placebo controlled phase I trial of safety, pharmacokinetics, pharmacodynamics and acceptability of tenofovir and tenofovir plus levonorgestrel vaginal rings in women . Thurman et al. (2018, 28 June). PLOS One. doi.org/10.1371/journal.pone.0199778

Rapid measures of user's adherence to vaginal drug products using attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and multivariate discriminant techniques . Adedipe et al. (2018, 25 May). PLOS One. doi.org/10.1371/journal.pone.0197906

Solid state 13C NMR spectroscopy provides direct evidence for reaction between ethinyl estradiol and a silicone elastomer vaginal ring drug delivery system . McCoy et al. (2018, 14 July). Europe PMC. doi.org/10.1016/j.ijpharm.2018.07.040

Unintended pregnancy in Gaborone, Botswana: A cross-sectional study. Doherty et al. (2018). African Journal of Reproductive Health. DOI:10.29063/ajrh2018/v22i2.8

Media Articles

Griffithsin considered as potential multipurpose prevention technology option. (2018, 1 January). Relias Media.

Learn before you leap: The catalytic power of a learning network. Ehrlichman, D. & Sawyer, D. (2018, 27 July). Stanford Social Innovation Review.

These are the only kinds of birth control that also protect against STIs . Miller, K. (2018, 27 July). SELF.

6 types of contraceptives you must know about . (2018, 31 July). Doctor NDTV.

In the Blogosphere

From the pipeline | Taking on a challenge - How an ambitious engineering goal led to an innovative MPT for HIV, HSV, and unintended pregnancy. Clark, M.R. & Dietz, K. (2018, 1 August). IMPT Secretariat.

Mathematical modelling and its potential to inform MPT development. (2018, 18 July). IMPT Secretariat.

The IMPT's "From the Pipeline" product developer blog series is continuing to expand. Contact us if you are interested in guest blogging or have content suggestions for this series or the blog more generally.

Press Releases

Evofem Biosciences' Chief Medical Officer, Dr. Kelly Culwell, to present at #BlogHer18 Creators Summit. (2018, 7 August). Cision PR Newswire.

Funding Opportunities

RFA-HD-19-015 Development of Novel Nonsteroidal Contraceptive Methods (R61/R33 - Clinical Trial Not Allowed) - NICHD is accepting applications to support and facilitate multidisciplinary research approaches for the development of novel nonsteroidal contraceptive products for women and men that act prior to fertilization, which could potentially include MPTs with contraceptive and infection prevention properties. This FOA aims to position innovative and validated methods for future clinical development. View the link above for more detailed information. Letters of Intent due 6 October 2018.

Career Opportunities

AVAC is now accepting applications for the 2019 Advocacy Fellows Program . This is an opportunity to build your advocacy skills in HIV prevention research and implementation. Visit the link for more information.

Announcements

Planning to attend ICFP 2018? Early-bird registration ends 31 August. Register now to save!

World Sexual Health Day is on 4 September. This year's theme is Sexual Health and Sexual Rights are FUNDAMENTAL for well-being. Chat with @CAMIhealth about @sexualhealthday on Twitter!

Save the Date! Scientists Advancing Affordable Medicines, Inc. (SAAMnow) is organizing its inaugural workshop: "Streamlining Generic Drug Development by Matching Reference Product Composition and Performance, In Vitro and In Vivo" to be held 18-19 October 2018 at the Embassy Suites in Baltimore, MD. This workshop will discuss cutting-edge approaches to facilitate the development of solid oral, semi-solid, long-acting injectable, and oral inhalation products, like MPTs. It will bring together industry and thought leaders, innovators and distinguished researchers with the latest scientific and business opportunities in Generic Drug Development. For full details and sponsorship opportunities, visit the link above and/or contact the organizers at [email protected] .

Save the Date! The 23rd International AIDS Conference will be held 6-10 July 2020 in San Francisco and Oakland, CA. Visit the link for the latest information.

Contact us if you and/or your colleagues are attending any upcoming meetings and conferences. We would be happy to provide you with materials to help enhance your presentations as related to MPTs and the MPT field.

Visit www.MPTs101.org and www.theIMPT.org , or click below

for more resources on MPTs.

IMPT Secretariat

1825 Bell Street, Suite 102

Sacramento, CA 95825

+1.916.987.6671

[email protected]

www.theIMPT.org

www.MPTs101.org