May/June 2020 Newsletter
In This Issue:
  • President's Message
  • Board Update
  • Research & Education: R&E Awards Highlights
  • Public Policy Update
  • Pharmacist Continuing Education Articles
  • A Review of the Use of Methicillin-Resistant Staphylococcus aureus Nasal Swabs for Antibiotic De-escalation
  • Vitamin C, Hydrocortisone, and Thiamine in Patients with Septic Shock: New Discoveries
  • Featured Clinical Topic: Critical Care/Pulm/Emergency Med
  • Pharmacogenomics in Mental Illness 
  • Review of E-cigarettes and Acute Lung Injury
  • Nebulized Naloxone for Opioid Intoxication
  • Evaluating the Use of Neuromuscular Blocking Agents in Acute Respiratory Distress Syndrome
  • Affiliate Chapter News and Events
  • Upcoming Newsletter Info
President's Message
By Alex Oschman, PharmD, BCPPS; Children's Mercy Hospital
"Put your mind towards anything and you’ll achieve what you want. And will you succeed? Yes! Yes, you will indeed, 98 and ¾ percent guaranteed." – Dr. Seuss

What a year it has been! I can’t say that when I took office as your president this time last year, that I could have predicted events over the past year! I hope many of you were able to attend our first VIRTUAL spring meeting. I want to again thank Becca, Jim, and all the members of the planning committee who did a wonderful job transitioning our regular meeting to a virtual format in such short notice! I thought you would be interested in some statistics from our spring meeting...

Board Update
By Davina Dell-Steinbeck, PharmD, BCPS-MSHP President Elect; SSM Health St. Mary's, St. Louis 

March
  • Board voted to cancel the in-person meeting and pursue a virtual meeting.

April
  • Restructured the Communications and Website Committees into one committee named the Website/Social Media Committee. This committee will be chaired by the Communications Director who will be the Secretary.
  • With this restructure, the Newsletter Committee will assume responsibility for as needed E-blast communication.
  • Education Committee will support the Newsletter Committee in planning educational content each year and peer review the Featured Clinical Topics.
  • 50th anniversary celebration moved to Fall. Awards from annual meeting will also be presented then. Details about the date for this are being arranged.
Research & Education Update
R&E Awards Highlights

By Jacklyn Harris, PharmD, BCPS, Christian Hospital/St. Louis College of Pharmacy
Although our Spring Meeting this year was virtual, we were still able to celebrate together and recognize all the great work Missouri’s pharmacists and student pharmacists have been doing. I was super impressed by the virtual posters. Each presenter put in a lot of hard work to both create a poster and then create a 5-minute video reviewing their work. I really enjoyed learning about each project, and most of the questions that I had from ...

Public Policy Update
May/June Public Policy Committee Update

By Nathan Hanson, PharmD, MS, BCPS, Health Trust Supply Chain
Have you ever wondered what the public policy committee does? As our previous article explained, you can learn about pharmacy by comparing it to sports, and in both settings, rules matter. (That has been taken to an extreme lately, because laws and rules have kept elite athletes on the sidelines!) The Public Policy Committee keeps an eye on 3 basic levels of pharmacy rules: Legislative, regulatory, and association. It has been a crazy couple months in healthcare rules, so we have put together just a few updates in all 3 spheres. Remember, MSHP matters. Collaboration is a priority. Things are changing. Stay engaged!

A Review of the Use of Methicillin-Resistant Staphylococcus aureus Nasal Swabs for Antibiotic De-escalation

By: Brandon Reynolds, PharmD, BCPS, PGY2 Pharmacy Resident, University of Missouri Health Care
Methicillin-resistant Staphylococcus aureus (MRSA) is found on the skin, axilla, groin, and nares, with the nares being the most common site of colonization.1 According to the Centers for Disease Control and Prevention (CDC) approximately 33% of patients have Staphylococcus aureus nasal colonization, while 2% harbor MRSA.2 Between methicillin-susceptible and MRSA strains, MRSA accounts for the majority of Staphylococcus aureus infections in intensive care units ...
Vitamin C, Hydrocortisone, and Thiamine in Patients with Septic Shock: New Discoveries

By: Lauren Jacobsmeyer, PharmD, PGY2 Pharmacy Resident, SSM Health Saint Louis University Hospital
Sepsis is a life-threatening illness characterized by a dysregulation in host response to infection characterized by circulatory, cellular, and metabolic abnormalitites.1 Sepsis and septic shock affect millions around the world each year. Sepsis is a primary cause of mortality in Intensive Care Units (ICUs), and its incidence has doubled in the last 10 years.2 Greater than 50% of hospital deaths are due to sepsis with the mortality rate increasing as ...
Featured Clinical Topic:
Critical Care/Pulm/Emergency Med
Pharmacogenomics in Mental Illness 

By Hannah Norris, PharmD, PGY1 Pharmacy Resident, Mercy Hospital Springfield
Pharmacogenomics and pharmacogenetics are misconceived to be synonymous terms, but there is a recognized difference between the two.1-2 Pharmacogenomics encompasses all genes in the genome that may determine response to a drug. This field of study evaluates differences in drug receptor activity, uptake, and breakdown of medications based on differences in genetic profiles. Pharmacogenomics can also be used to aid in targeted drug development ...

Review of E-cigarettes and Acute Lung Injury 

By Eric Zhang, PharmD Candidate 2021,
St. Louis College of Pharmacy

Mentor: Paul Juang, PharmD, BCPS, BCCCP, FASHP, FCCM; St. Louis College of Pharmacy
Electronic cigarettes (E-cigarettes) and the subsequent act of using E-cigarettes, or vaping, were introduced in the US in 2007 and have become increasingly popular among youth and adults. 1 In a 2019 survey, 27.5% of high school students and 10.5% of middle school students reported use of E-cigarettes in the last 30 days ...

Nebulized Naloxone for Opioid Intoxication

By Marissa Chow PharmD Candidate 2021, Michelle Tulchinskaya PharmD Candidate 2022, and Lauren Busch PharmD Candidate 2022, St. Louis College of Pharmacy

Mentor: Sarah Cook, PharmD, BCPS; SSM Health St. Joseph Hospital – St. Charles
In 2018, 2 million people in the United States were diagnosed with an opioid use disorder, and 47,600 people died as a result of opioid overdoses. 1 The rate of opioid overdoses has tripled since 2000 and continues to rapidly increase. 2 Since the start of the opioid epidemic in the 1990s , there have been several programs and products developed to help combat this rapidly growing issue. 3 The mainstay of treatment for opioid overdose is naloxone, which has seen dramatic increase in use within ...

Evaluating the Use of Neuromuscular Blocking Agents in Acute Respiratory Distress Syndrome

By Shannon Jones, PharmD, PGY1 Pharmacy Resident, Mercy Hospital St. Louis
Acute respiratory distress syndrome (ARDS) is a type of acute, diffuse inflammatory lung injury, leading to increased pulmonary vascular permeability, increased lung weight and loss of aerated lung tissue. The LUNG SAFE study in 2016 found that ARDS accounts for ~10% of ICU admissions and 23% of ventilated patients. The mortality rate has been reported as high as 25 – 40% in most studies. The main causes ...

Affiliate Chapter News & Events
Greater Kansas City Society of Health-System Pharmacists (GKCSHP) 

President: Melanie Smith, PharmD, BCPS ( Melanie.Smith4@hcamidwest.com


Mid-Missouri Society of Health-System Pharmacists (MMSHP) 

Join us at Advancements in Lipid Emulsions: The Emergence of Smoflipid® Lipid Injectable Emulsion, USP 20%' on Thursday, 07/23/2020 at 06:00 PM CT at CC City Broiler with Phil Ayers. 

Like us on Facebook! www.facebook.com/mymmshp/   

President :  Emily Roehrs, PharmD ( wiederanderse@health.missouri.edu


Saint Louis Society of Health-System Pharmacists (STLSHP) 

President : Erin Hennessey, PharmD, BCPS ( Erin.Hennessey@stlcop.edu


Southeast Missouri Society of Health-System Pharmacists (SEMSHP) 


President : Janice Bueter, PharmD, BCPS ( jbueter@sehealth.org
Upcoming Newsletter Info
Upcoming Featured Clinical Topics 

July/Aug 2020 – Cardiology/Anticoagulation   FULL

Sept/Oct 2020 – Pediatrics 

Nov/Dec 2020 – ID/Vaccines FULL

Submit to:  Sarah Cook
Newsletter Submission Deadlines:

July/August 2020: July 13th

Sept/Oct 2020: September 14th

Nov/Dec 2020: November 9th
Newsletter Submission Guidelines

  • Pharmacists, pharmacy technicians, and pharmacy students in Missouri are eligible to submit content for publication in the MSHP Newsletter. Student submissions need to include pharmacist oversight.

  • Submit content to the current Newsletter Committee Chair on or before the established deadlines.

  • CE and Featured Clinical Topics must be approved by the Newsletter Committee Chair in advance of article submission, to prevent duplicates. Duplicate articles submitted without advanced approval may not be published.

  • Recommended length of submissions for committee, affiliate, college/schools of pharmacy, and student chapter reports is half to one page in length.

  • Recommended length of submissions for featured clinical topics is 1 to 2 pages, without references.

  • Recommended length of CE articles is individualized, based on the amount of CE provided.

  • Recommended length of submission for other categories is 1 to 2 pages.
MSHP Board of Directors & Committee Chairs
2019-2020 Board Members

President:   Alex Oschman

President-Elect:   Davina Dell-Steinbeck

Immediate Past President:   Tony Huke

Secretary:  Barb Kasper

Treasurer:   Christina Stafford
2019-2020 Committee Chairs

Vendor Relations Board Liaison -  Evanna Shopoff

Membership Committee -  Erin Hennessey

Communications Committee -  Barb Kasper

Public Policy Committee -   Sarah Cox

Newsletter Committee -  Laura Challen

Education and Programming -  Elizabeth Englin

Website Committee -  Lori Rio
Questions & Comments
If you have any questions, comments, or wish to submit an article to for MSHP Newsletter, please contact the Newsletter Committee Chair (  Laura Challen )  or another Newsletter Committee member.

2019-2020 MSHP Newsletter Committee Members
Laura Challen , PharmD, MBA, BCPS, BCACP (Chair)
Sarah Cook , PharmD, BCPS (Vice-Chair)
Rebecca Nolen , PharmD, BCPS, BCIDP, AAHIVP
Hannah Pope , PharmD, BCPS
Emily Shor , PharmD