MESSAGE FROM LEADERSHIP
Dear McCance community,
 
The start of 2023 has been filled with excitement and productivity. Since January we have achieved key milestones for the launch of our national multi-institution REACH study, made strides toward the launch of our first-of-its kind Clinical Trial platform, expansion of the Brain Care Score within clinics and partners across the globe, and the initial launch of the Human Sleep Project's Data Science Platform. Finally, we visited Yale’s newly-launched Center for Brain and Mind Health as well as Oxford University’s Nuffield Department of Population Health to begin discussion of the launch of formal alliances. 
 
While the flutter of activity is energizing, we are ever mindful of our cause. In January this community lost perhaps the Center's deepest source of inspiration, Allison McCance. Allison was Henry's wife of over 50 years and the inspiration for the launch of the Cure Alzheimer’s Fund 20 years ago and our own Henry and Allison McCance Center for Brain Health just five years ago.  
  
Allison’s life force has animated everything we do here at the Center. Her loved ones confronted the tragedy of her early diagnosis with Alzheimer’s Disease with the most generous philanthropic devotion to future generations imaginable: a commitment to doing all they could to ensure that others would not have to endure the suffering Allison and her family endured. Henry’s stories about his love for Allison, and how he took inspiration and a call to action from her diagnosis, are legendary. All of us who have had the privilege of listening to Henry speak of Allison and their partnership have been deeply moved.

As we go forward, we do so with Allison’s memory and inspiration in mind. Together we believe we can create a future where this devastating disease no longer brings the anguish it does today.
With hope and vigor,

Jonathan Rosand, MD, MSc, Managing Co-Director
Rudy Tanzi, PhD, Co-Director
Greg Fricchione, MD, Co-Director
McCance Initiatives, Faculty, Clinicians Making an Impact
McCance Center Managing Co-Director and Co-Founder Dr. Jonathan Rosand discusses the current state of Brain Care, the global health crisis, and the McCance Center’s mission to drive the right initiatives to intervene earlier for better Brain Health for all.
Lead Research Fellow Dr. Sanjula Singh and Lead Research Coordinator Brigitte Jacoby discuss the exciting new research study launched at the McCance Center. The REACH study connects brain health, blood pressure, and social determinants of health.
To assist in conversations with patients, we’ve created an accessible resource page with recommendations and best practices on ways to improve the metrics of your Brain Care Score. 
It’s been more than 10 years since Drs. Sonia Vallabh and Eric Minikel founded the Prion Alliance to develop therapeutics for human prion disease. In a recent interview we learned where they are in the clinical trial process. 
Driving the Conversation on Brain Health: McCance Center in the Media
Rudy Tanzi and the Latest Alzheimer's Drugs - part 1

Rudy Tanzi and the Latest Alzheimer's Drugs - part 1 Will 2023 be a boom or bust year for new Alzheimer's drugs? In this episode of BrainStorm host Meryl Comer talks with Dr. Rudy Tanzi, Vice-Chair of Neurology at Massachusetts General Hospital,...

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www.usagainstalzheimers.org
Dr. Rudy Tanzi -The Latest on Alzheimer's Drugs (part 2)

BrainStorm host Meryl Comer talks with Dr. Rudy Tanzi, Vice-Chair of Neurology at Massachusetts General Hospital, Co-Director of the McCance Center for Brain Health and Professor at Harvard Medical School. Hear what Dr. Tanzi discovered through...

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www.usagainstalzheimers.org
Mediterranean and MIND diets reduced signs of...

Sign up for CNN's Eat, But Better: Mediterranean Style. Our eight-part guide shows you a delicious expert-backed eating lifestyle that will boost your health for life . People who consumed foods from the plant-based Mediterranean and...

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www.cnn.com
UPCOMING EVENTS
McCance Center for Brain Health Seminar Series - Ongoing and open to the public
Every two weeks the McCance Center hosts faculty seminars featuring the latest research on brain health from globally recognized experts. Guests are welcome to listen in on the McCance Center for Brain Health Seminar Series. Email [email protected] to receive lecture invites. Watch previous lectures on video here.
Alzheimer’s Clinical and Translational Research Unit (ACTRU)
Monday, March 20, 11:00 AM ET
ACTRU takes a multidisciplinary, basic science-to-clinic translational approach to designing patient-oriented experimental and clinical trials for aging, dementia, and other neurodegenerative disorders. These involve advanced digital health assessments, neuroimaging, and ultra-sensitive molecular biomarker detection technologies in blood, cerebrospinal fluid, and brain tissue.
Jose Galluci, MD, MSc
Monday, April 3, 11:00 AM ET
Dr. Galluci is the director of ECT and Video EEG Services at the Institute of Psychiatry, University of Sao Paulo - FMUSP – Brazil.
Follow us on social media and visit our website to get the latest news
on our clinical programs and research initiatives.
If you would like to learn more about how you can support
the McCance Center for Brain Health, please contact Bridget Flynn
at [email protected], 508-961-8093, or link here.