The Premature Microbiome and Outcomes (PREMO) study, a BCMM collaborative with the UCSF Preterm Birth Initiative, is actively enrolling participants from the Prediction of Maturity, Morbidity and Mortality in Preterm Infants (PROMPT) and the Healthy Outcomes of Pregnancy (HOPE) studies. PREMO aims to develop a greater understanding of the role of the early-life microbiome in preterm infant development. To date, PREMO has received samples from more than 65 mother-infant pairs at time points spanning the pre-, peri-, and post-natal periods. Just this month, we enrolled our first two preterm participants who are receiving care in the NICU at the UCSF Benioff Children's Hospitals in San Francisco. These precious samples will increase our understanding of how the early life microbiome programs immune function and relates to clinical outcomes in later life. It also aims to build the foundation for future BCMM-funded studies. Ultimately, data and sample resources generated through this initiative will be made available to the BCMM community to support additional integrative research opportunities. |