MONTHLY DIGEST

October 2026

Migraine Is Not One Disease, but Many: New Insight from a Machine Learning Study


Diagnostic modeling using non-headache features, along with phenotypic modeling, supports the idea of migraine as a spectrum disorder.

 

The Face of Pain: Machine Learning Video Analysis of Facial Grimace and Body Position Enables Study of Sound-Evoked Pain in Mice

Researchers validate the approach in a CGRP-induced migraine model, and successfully quantify the behavioral response to loud sound.

Understanding the Full Burden of Headache Disorders: A Conversation with Andreas Husøy

“The problem of headache disorders is much bigger than people imagine. It affects so many people, especially when you are talking about the most common conditions, migraine and tension-type headache. In my day-to-day clinical practice, I only see a very small fraction of the individuals who are living with these diseases. These people are the ones who are most severely affected by headache; they live with a very high frequency of headache or severe pain. But when you look at the global data, you understand that the people who seek out medical care are really just the tip of the iceberg.” – Andreas Husøy

Biweekly Literature Recaps

 

New Editor's Picks

Early pregnancy use of anti-CGRP monoclonal antibodies and propranolol and spontaneous abortion risk

Hemiplegic migraine: genetics and pathophysiology

Pharmacologic treatment for migraine prevention in adults practice guideline recommendations: Report of the AAN Guidelines Subcommittee and the American Headache Society

Professional Resources

Upcoming Events, Grants, and More

Call for Papers for the Jes Olesen Awards for the Advancement of Headache Medicine

20th European Headache Congress

Neuroscience 2026

In Case You Missed It

The Impact of US Government Science Policies on the Migraine Field: An Update

A New Piece for the Migraine and Stroke Risk Puzzle

Toward a Better Understanding of Vestibular Migraine: A Conversation with María Dolores Villar-Martínez

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The Migraine Science Collaborative is a program of the Association of Migraine Disorders.

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