DISCOVERIES
February 2021
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Mining “junk DNA” reveals a new way to kill cancer cells
Sanford Burnham Prebys scientists have uncovered a drug candidate, called F5446, that exposes ancient viruses buried in “junk DNA” to selectively kill cancer cells. Published in the journal Cell, the proof-of-concept study reveals a previously unknown Achilles’ heel for cancer that could lead to treatments for deadly breast, brain, colon and lung cancers.
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Scientists design potential drug for triple-negative breast cancer
A drug that holds promise as a treatment for triple-negative breast cancer—an aggressive cancer with limited treatment options—has been designed by Nick Cosford, Ph.D. Details about how the drug works to overcome treatment resistance were published in the Journal of Medicinal Chemistry.
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A new kind of seminar series launches
Svasti Haricharan, Ph.D., and Ze’ev Ronai, Ph.D., launched a new series of virtual seminars that connect established scientists with rising stars to answer important questions about cancer. The monthly events aim to engage scientists from around the world and foster collaborations that advance the fight against cancer.
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Evan Snyder named Fellow of the American Institute for Medical and Biological Engineering
Renowned stem cell researcher Evan Y. Snyder, M.D., Ph.D., professor and founding director of the Center for Stem Cells and Regenerative Medicine, has been elected to the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE). Snyder was elected by his peers and members of the College of Fellows for his seminal contributions to regenerative medicine.
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Get to know cancer researcher Karina Barbosa Guerra
We caught up with graduate student Karina Barbosa Guerra to learn more about her work to find better treatments for leukemia—and the moment she decided she wanted to be a scientist.
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Meet rare disease scientist Jonatan Matalonga-Borrel
Jonatan Matalonga-Borrel, Ph.D., is on the hunt for a treatment that could help children born with a rare, life-threatening condition called Alagille syndrome. Learn more about his research and his life outside of the lab.
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COVID-19: The way forward, one year later
This March marks one year since the outbreak of the COVID-19 pandemic that upturned our lives. At this "Insights" event, our experts will share research revelations from the past year, the latest scientific updates, and strategies for the path forward. The event takes place on Tuesday, March 23, from 1:00 p.m. to 2:00 p.m. PT.
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Spotlight on women’s health research
If you're a woman, you're at greater risk of many serious health conditions, including breast cancer, autoimmune disorders and more. At this "Insights" event, our top scientists will discuss their latest research into conditions that uniquely affect women. The event takes place on Tuesday, April 20, from 1:00 p.m. to 2:00 p.m. PT.
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Padres Pedal the Cause goes virtual for 2021
Calling all cancer fighters! Padres Pedal the Cause is going virtual for 2021, and registration is now open. This annual event raises critical funds for local cancer research institutes. This year's experience will take place on Saturday, May 8. Join the Sanford Burnham Prebys team, and help scientists put an end to cancer.
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How scientists are fixing "broken hearts"
Atrial fibrillation, often called AFib, is the most common cause of an irregular heartbeat. Even when symptoms aren’t obvious, AFib can increase the risk of stroke and related heart problems. At this "Insights" lecture, our scientists shared how they're working to protect, mend and regenerate "broken hearts."
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New research into slowing memory loss or dementia
Tim Huang, Ph.D., shared how his research comparing early-onset and late-onset Alzheimer's disease may lead to treatments that slow or reverse memory loss and dementia. This presentation was held in partnership with the Fleet Science Center.
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Does DNA editing in the brain cause Alzheimer’s disease?
Jerold Chun, M.D., Ph.D., explained his latest Alzheimer's research showing that certain DNA edits in the brain may underlie the disease—and how an FDA-approved drug may offer near-term hope. This presentation was held in partnership with San Diego Independent Scholars.
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Sumit Chanda, Ph.D., explains his lab's race to find an existing drug that can treat COVID-19.
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Read how a 1960s discovery made by Hudson Freeze, Ph.D., led to today's COVID-19 tests.
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At Sanford Burnham Prebys, we're passionate about finding bold new ways to treat disease, and we recognize the importance of sharing our discoveries with the public—especially during this unprecedented time. Find out where and when you can "meet" our scientists virtually and learn about their research in this community event calendar.
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Double your COVID-19 donation
Only research will allow scientists to understand and stop COVID-19. We are hopeful that our work will emerge as part of the larger solution to this global health crisis, and we invite you to accelerate our progress and impact. If you donate today, your gift will be matched dollar for dollar—up to $500,000—thanks to the generosity of Dinah Conyers Ruch.
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Could you benefit from the CARES Act of 2020?
The CARES Act of 2020 offers a once-in-a-lifetime opportunity to make transformative philanthropic gifts, with significant tax benefits to you and your family. Cash gifts to charities such as Sanford Burnham Prebys are deductible at 100% of adjusted gross income.
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