New Scale News
Laboratory Automation Edition 

We're excited that imec has begun shipping its Neuropixels 1.0 probes and we look forward to supporting your work with these high-density silicon probes.

Probe mount available now for Neuropixels 1.0 probes   

New Scale Probe Mount 1A  is available now for imec Neuropixels 1.0 silicon probes.

This mount accepts both types of Neuropixels 1.0 probes: with the flat silicon cap or the stainless steel dove-tail cap. 

The probe holder is designed to work with the New Scale Multi-Probe Micro-manipulator (MPM) System, but can be adapted for use with other manipulators.

The Promise of High-Density Silicon Probes for Neural Research
In a recent article in Neuron,    "Cracking the Function of Layers in the Sensory Cortex,"  Hillel Adesnik and Alexander Naka  outline the road map to overcome the existing conceptual and technical challenges for obtaining a detailed understanding of the role of cortical layers in sensory computation and perception.

They write: 

... recent technological advances finally allow for the execution of the experiment that Hubel and Wiesel prescribed, as well as many other sophisticated assays that can overcome this conceptual challenge. The holistic approach that understanding the cortex calls for is no longer beyond reach. 

Several emerging technologies will soon make combining large-scale recording with extremely precise perturbations of neural activity experimentally possible. These technologies include:

  • Major advances in silicon probe technology providing extremely compact multi-electrode arrays with up to 1,000 contacts now permit simultaneous physiological access to dozens of brain areas, and just as importantly, densely within and across layers.
  • Clever mechanical systems for inserting multiple of these probes into the same head-fixed animal should allow tracking the activity across all layers of each area and across a series of connected areas in the cortical hierarchy simultaneously.
  • Adding micro-LEDs or optical waveguides directly onto these probes could provide optical control over their full extent so that investigators could optogenetically control specific layers and within specific cortical areas.
  • Large scale multiphoton imaging.
The Multi-Probe Micro-manipulator System is one such clever mechanical system. 

Learn more

Get the full article in Neuron VOLUME 100, ISSUE 5, P1028-1043, DECEMBER 05, 2018.
The first manipulator designed specifically for silicon neural probes
MPM with 8 probes
The MPM Multi-Probe Micromanipulator System provides convenient, automated positioning of multiple neural probes for acute in-vivo recording. Simple to set up and operate, it is the first micro-manipulator designed specifically for use with silicon probes.

The compact design allows for independent positioning of multiple probes in the smallest space, with ample clear area for a virtual task environment. Automatically and independently move each probe to the optimum location in the brain.

MPM System distributors
We're pleased to welcome IWOO Scientific Corporation as our newest distributor, providing sales and support of the MPM System in Korea. 
Neural interface technology, components, systems, and software

Silicon neural probe technology
Advanced research instrumentation sales and support in Germany
Distributor of NeuroNexus probes in Japan
Distributor of NeuroNexus probes in China
Leadi ng  provider of  life sciences instruments in Korea
Contact us directly for 
other regions and probes
About Us

New Scale Technologies develops small, precise and smart motion systems for critical adjustments of optics, and many other micro positioning applications. Our tiny "all-in-one" motion modules with embedded controllers are easy to integrate into next-generation instruments for medical, scientific and industrial applications. They speed development time and deliver best-in-class performance in handheld, portable and laboratory systems

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