Join us for our next webinar on February 18 at 1:00pmET featuring Karen Hirschi, University of Virginia. Her presentation is titled "Regulation of Endothelial Cell Specialization"
For more details and to register,
On March 4, we will welcome Guillermo Oliver
of Northwestern University. His presentation is titled, "Lymphatics in organ growth and repair." More information is here
ASIP Welcomes NAVBO to EB2021
NAVBO members can attend Experimental Biology 2021 as guests of the American Society for Investigative Pathology. NAVBO is sponsoring a session called, The “Ins” and “Outs” of Vascular Inflammation, organized by William Muller, Northwestern University, featuring speakers: Klaus Ley, La Jolla Institute for Immunology; Sussan Nourshargh, Barts and The London School of Medicine; and Ira Tabas, Columbia University Medical Center. This session will take place on Tuesday, April 27 from 2:00 to 5:00pm EST.
Please join us!
Register for the meeting here
Abstracts are being accepted through February 4 - click the image for details!
Next Journal Club
The February 25 Journal Club will feature the paper:
"Arterialization requires the timely suppression of cell growth"
Authors: Wen Luo, Irene Garcia-Gonzalez, Macarena Fernández-Chacón, Verónica Casquero-Garcia, Maria S Sanchez-Muñoz, Severin Mühleder, Lourdes Garcia-Ortega, Jorge Andrade, Michael Potente, Rui Benedito
Nature 589, 437–441 (2021).
The journal club features a 30-minute presentation followed by a 30-minute Q&A. The overview of the paper will be presented by Ziqing Liu, University of North Carolina at Chapel Hill.
Our journal clubs are sponsored by the NAVBO Education Committee and are organized and moderated by committee member, William Hughes from the Medical College of Wisconsin.
Journal Clubs are limited to active/current NAVBO members. The registration link can be found in the Journal Club's forum on our web site: https://www.navbo.org/forum/02-21journal-club. You can also post comments, questions, etc. here before the presentation so that they can be addressed during the presentation and of course following the presentation to continue the conversation.
The session will be recorded, so register even if you can't attend the live presentation and receive a link to the recording automatically.
Consider joining us!
Request for NAVBO Session Proposals
Organize and Moderate an Online Session
This is an opportunity to organize and moderate a session for NAVBO's New Online Symposia Series. We are seeking proposals from current regular members.
Our online meeting formats have proven to be very successful both before and during the pandemic; we believe that they will continue to be successful!
For several years we have sought session proposals for inclusion in the annual meeting. However, this limited us to choosing only one or two proposals for presentation. By moving this function to a bimonthly online forum, we will broaden the scope of the audience, provide opportunities to more members and provide the much requested free time to the annual meeting attendees.
We are asking our current regular members* to propose a 1-1.5 hour session with three speakers in a field that is relevant to the vascular biology community. Proposals will be reviewed and selected by a committee.
We believe that this will be a great way to cover the broad scope of material within the vascular biology field.
Submit your proposal today at:
(if the pdf doesn't open automatically, click the download icon within your browser, then choose Open with Adobe Acrobat)
* Current regular members: independent investigators whose membership is up to date.
Lab of the Month - January 2021
The Lab of Dr. Song Hu
Lessons Learned (from the January 14 issue)
First, I want to thank the NAVBO Education Committee for inviting me to contribute to the Lessons Learned series, which gives me an opportunity to reflect on my professional development in the past few years during this unusual holiday season.
I started my own research program at the University of Virginia in 2013 and was recently recruited back to my alma mater, Washington University in St. Louis. I am an imaging scientist and biomedical engineer by training, and I am thankful to my mentors, collaborators, and colleagues at Washington University and the University of Virginia, who introduced me to cerebrovascular and cardiovascular research and have helped me leverage the impact of our imaging technologies in these exciting fields.
Making the transition from a trainee in a well-established lab to a junior PI who was expected to build a new research program from scratch is probably one of the biggest challenges I have ever faced in my career. Looking back, I have made some right moves but also many mistakes. I would like to take this opportunity to share some of them with those who are expecting or in the process of this transition.
Establish your own niche as early as possible. One question that you might have been repeatedly asked during faculty interviews is how you will distinguish yourself from your mentors (and peers). Indeed, identifying and establishing your own niche early in your career is key to a successful transition to an independent PI. One important piece of advice I have received is that you want to work on something that only you can do or you can do best.
finding the right balance between hands-on and hands-off mentoring, being strategic when expanding your research program, and letting application drive technology development.
Summer Training for Junior Faculty
Programs to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE)
The PRIDE Summer Institute Program in Cardiovascular Disease Comorbidities, Genetics and Epidemiology to Increase Diversity Among Individuals Engaged in Health-Related Research is now accepting applications. Space is limited for the 2021 mentored summer training programs so apply early!
Eligible applicants are junior-level faculty or scientists with a background that is under-represented in the biomedical or health sciences, and are United States Citizens or Permanent Residents. Research interests should be compatible with those of the National Heart, Lung, and Blood Institute (NHLBI) in the prevention and treatment of heart, lung, blood, and sleep (HLBS) disorders.
Our All-Expense paid Summer Institute program with effective mentored training opportunities to enhance the research skills and to promote the scientific and career development of trainees with a research interest in Cardiovascular disease Comorbidities, Genetics and Epidemiology.
Trainees will learn effective strategies for preparing, submitting and obtaining external grant funding for research, including extensive tips on best practices.
Welcome to our New Members:
Martijn Cox, Xeltis BV
Katrien De Bock, ETH Zürich
Luisa DiPietro, UIC College of Dentistry
Kairbaan Hodivala-Dilke, Barts and the London School of Medicine and Dentistry
Anali Iglesias Gonzalez, Florida International University
Kelli Jablon, Tulane University
Helle Jørgensen, University of Cambridge
Celeste Nelson, Princeton University
Josef Penninger, University of British Columbia
Manu Platt, Georgia Tech
Rhonda Prisby, University of Texas at Arlington
Andy Y. Shih, Seattle Children’s Hospital
Toshiharu Shinoka, Nationwide Children's Hospital
Recent Publications by NAVBO Members
Comprehensive phenotyping of endothelial cells using flow cytometry 1 : Murine
Cytometry Part A
The endothelium forms a selective barrier between circulating blood or lymph and surrounding tissue. Endothelial cells play an essential role in vessel homeostasis, and identification of these cells is critical in vascular biology research. However, characteristics of endothelial cells differ depending on the location and type of blood or lymph vessel. Read more
Comprehensive phenotyping of endothelial cells using flow cytometry 2 : Human
Cytometry Part A
In vascular research, clinical samples and samples from animal models are often used together to foster translation of preclinical findings to humans. General concepts of endothelia and murine‐specific endothelial phenotypes were discussed in part 1 of this two part series. Here, in part 2, we present a comprehensive overview of human‐specific endothelial phenotypes. Read more
The vascular origins of antero-medial tibial bowing in congenital fibular deficiency
The Anatomical Record
Anteromedial bowing and shortening of the tibia are intrinsic features of limbs with congenital fibular deficiency (CFD). Tibial bowing occurs more frequently when the fibula is radiographically absent rather than deficient. Read more
Open Call for Lipedema Research Proposals
Collaborative Research Award - Designed for team research that requires involvement of multiple institutions or muIti-disciplinary researchers. Applications that involve current LF grantees receive priority review. Up to $250,000 over two years.
Proof of Concept Award - Designed to support development of preliminary data for highly innovative hypotheses. Open to investigators of any career stage or background. Successful awards are eligible for streamlined award renewal. Up to $125,000 for one year
Mentored Award - Designed to support postdoctoral research experiences for candidates in non-independent mentored research training. Intended to support PhD (or equivalent research degrees) and clinicians engaged in mentored medical research. Up to $70,000 for two years
· Application Portal Opens: January 19, 2021
· LOI Submission: March 15, 2021; 11:59 PM EST
· Video Presentation with Lipedema Foundation staff and Full Application Invitations: April 2021
· Full Application Submission: June 26, 2021
· Award Status Update: August 31, 2021
· Earliest Project Start Date: October 1, 2021
Dates are subject to change at discretion of Lipedema Foundation. Registered applicants will be notified by email should these dates change.
Specific Areas of Interest
While the Foundation will consider all proposals, those that are oriented towards improving diagnosis of patients will be prioritized in the current cycle.
Applicants should consider the development of local surgeon-researcher teams that will facilitate access to fresh, well-characterized patient biological samples and appropriate controls.
Investigators requiring assistance with recruitment of patients or acquisition of biological samples should contact the Foundation at least 3 weeks prior to LOI submission to review feasibility of the request.
Proposals to create clinically relevant animal models should clearly justify the relationship of the proposed model to a genetic or biomechanical feature of Lipedema.
For questions regarding this RFP, please contact the Lipedema Foundation staff by email at email@example.com.
How to Apply
All applications must be submitted through the Lipedema Foundation research submission portal.
Please visit their website to find the link to the submission portal.
Industry News (from the January 14 issue)
Desperate times drive creative approaches to global medical need
Ian Sample, writing in The Guardian
(15 Dec 2020), describes the costly upside of the efforts required to effectively combat the COVID-19 pandemic, which necessitated a extraordinary global collaboration that has led to novel vaccines, therapeutic approaches, and the promise of new discoveries to come. Included is an account of novel steps taken by NIH Director Francis Collins to forge a partnership among the FDA, the CDC, and the largest pharmaceutical companies, aiming to set priorities and milestone accomplishments to accelerate COVID-19 therapeutic interventions and vaccines (“Activ”). Activ whittled an initial list of 640 potential therapies down to a number manageable by clinical trials, and the NIH advanced these to testing. A special federal appropriation was used to underwrite 100+ projects to develop rapid diagnostic testing. Within the month, the fruits of this labor are expected to enable an additional 2 million SARS-CoV2 tests per day.
Fellowship opportunity for women postdoctoral scientists
The 2021 L’Oréal USA For Women in Science program, founded on a belief that women in science have the power to change the world, is now accepting applications. This year’s fellowship program, conducted in partnership with AAAS, will provide five women postdoctoral scientists with $60,000 grants to support their contributions in STEM fields and encourage their service as role models for future generations. Now in its seventeenth year in the U.S., the For Women in Science program has awarded 85 postdoctoral women scientists over $4 million in grants. The 2020 winners included a bioengineer, diabetes researcher and a neuroscientist. Information on eligibility and the application process may be found here
ASH leads efforts to standardize clinical study of COVID-related thrombosis
Deborah M Siegal et al.
have published “A toolkit for the collection of thrombosis-related data elements in COVID-19 clinical studies” in the Dec 2020 issue of Blood Advances
. While thrombosis is regarded as a major complication of COVID-19, particularly in those with severe illness, differences in study design, patient populations, outcome ascertainment, and other parameters have limited the establishment of generalized prognostic criteria and treatment standards. To address these challenges, a task force of the American Society of Hematology, in collaboration with a similar group from the International Society on Thrombosis and Haemostasis, have developed sets of standardized data elements in critical clinical domains. The authors maintain that use of such standardized variables in multiple clinical studies should enhance comparison of results among them.
Frontiers in Cardiovascular Medicine
Special Research Topics
Putting Engineering Back In Vascular Tissue Engineering To Advance Basic Science and Clinical Applications
Topic Editors: Jessica Wagenseil (Washington University in St. Louis) and W. Lee Murfee (University of Florida).
This topic is sponsored by NAVBO
Vascular tissue engineering (VTE) can be characterized as the creation of replacement vessels. Over the past 30 years, approaches have incorporated different combinations of extracellular matrix scaffolds, cells and biological active chemical cues. Challenged by the goal to recapitulate the complexity of big or small vessels, the clinical use of in vitro tissue engineered vessel replacements is still limited. With research more often focusing on reductionist materials science or cell biology characterization of vessel-like constructs, an opportunity has emerged to re-apply engineering approaches to guide the next step in VTE.
Manuscript submission deadline has been extended; for more information, click here.
Experimental Biology 2021
February Journal Club
Call for Session Proposals
Lab of the Month
Spotlight on Trainees
Summer Training Program
Call for Proposals -
Calendar of Events
And below . . .
VB2020 Guest Societies
Shop NAVBO Items
Subscribe to the VBPA
NAVBO Career Center
Help support our trainee scholarships
Any profits from the sale of these NAVBO items will help fund additional scholarships for students in the Advancing Young Voices Through Diversity and Inclusion Program. Thank you for your support!
Vascular Biology Publications Alert Now Available by Subscription
The NAVBO Vascular Biology Publications Alert will now be available to non-members for a $55 a year subscription. If you would like to receive this alert, but are not a member, please contact Danielle at firstname.lastname@example.org.