August 23, 2018

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Meetings
 
 
Vascular Biology 
Newport, RI 
October 14-18, 2018 

Lymphatic Forum 2019
Austin, TX
May 31 - June 1, 2019

Next webinar is Sept 13
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NAVBO Privacy Policy
Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes. Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
 
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25.   The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
 
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Meet One of our New Councilors
Kristy Red-Horse, Ph.D.
Kristy Red-Horse, Ph.D. is an Assistant Professor in the Department of Biological Sciences at Stanford University. Dr. Red-Horse received her Ph.D from the University of California, San Francisco. Her graduate research was performed in Dr. Susan Fisher's laboratory and investigated vascular remodeling in the uterus and placenta during pregnancy. She completed postdoctoral training with Dr. Mark Krasnow at Stanford studying coronary artery development in the embryonic heart.
 
Dr. Red-Horse's research continues to investigate coronary artery development and regeneration. Using whole organ imaging and mouse genetics, the laboratory focuses on deciphering progenitor lineages, angiogenesis factors, and mechanical regulation of coronary endothelial cell migration and arterial specification. Their long-term goal is to identify developmental mechanisms that can by utilized to stimulate coronary artery regeneration in the diseased and injured heart.
Vascular Biology 2018 - More Opportunities!

Late-Breaking Abstracts
We are accepting late-breaking abstracts for Vascular Biology from now through September 10.  All late-breaking abstracts will be presented as posters.  These submissions cannot be considered for Travel Awards, but they will be considered for the onsite Poster Award Competition (trainees only). Go to http://www.navbo.org/events/vb2018/abstracts   to submit your abstract! 
Schedule
There is now an easy to read schedule of the meeting on the web site.  It does not yet include abstract presentations since they are currently under review.
Letter to Grantees from Francis Collins
NIH Director Francis Collins, addressing active domestic NIH grantees and their institutions, has issued an appeal for vigilance and cooperation in safeguarding the fruits of US biomedical research efforts.  Dr. Collins notes that "NIH is aware that some foreign entities have mounted systematic programs to influence NIH researchers and peer reviewers and to take advantage of the long tradition of trust, fairness, and excellence of NIH-supported research activities."  He includes a reminder that grant applicants and awardees are obliged to disclose all forms of other support and potential conflicts of financial interest, including support coming from foreign governments or other offshore entities.  Read Dr. Collins' Letter.
Funding Opportunities from NHLBI
NHLBI Funding Opportunity - Deadline Approaching
The Vascular Biology and Hypertension Branch of NHLBI is seeking applications to the following funding opportunity:
RFA-HL-17-22: Maximizing the Scientific Value of the NHLBI Biorepository: Scientific Opportunities for exploratory Research (R21).

This funding opportunity is to support meritorious exploratory research relevant to the NHLBI mission using the biospecimen collections that are stored in the NHLBI Biorepository and that are available through BioLINCC.  

The next due date for non-AIDS applications is October 17, 2018. Requests must be submitted to BioLINCC no later than September 26, 2018 in order to be eligible to receive a Letter of Availability by this due date.

The next due date for AIDS applications is January 7, 2019. Requests must be submitted to BioLINCC no later than December 17, 2018 in order to be eligible to receive a Letter of Availability by this due date.

For more information on RFA-HL-17-022 please visit:
To view available biospecimen collections and initiate a request, please visit:  
Next NAVBO Webinar
Fast interactive genomics data visualization in AltAnalyze
Join us on September 13 at 1:00pm ET as Dr. Nathan Salomonis, Ph.D., an Assistant Professor in the Division of Biomedical Informatics at Cincinnati Children's Hospital Medical Center.  This webinar is free to all NAVBO members.  Non-members pay $25 per webinar. Read more about next month's webinar and Dr. Salomonis.
Research!America to Host Annual Forum
The annual National Health Research Forum, sponsored by Research!America, will take place on September 6 at the Newseum in Washington from 10:15 am - 2:30 pm EST.  Distinguished leaders will gather for straight talk about the science behind medical and public health p  rogress. Dr. Jan Kitajewski, former NAVBO President, will attend as the NAVBO Representative.  Discussions will include: How can we outpace drug-resistant superbugs? How is the BRAIN initiative changing the trajectory of neuroscience?  Is digital health the future of health care?  
 
The forum is at capacity, but please check our website for the livestream link, which will be posted soon.  R!A urges you to capture the content for use in workshops and classrooms. 
Grant Opportunity
Orphan Disease Center
The ODC offers over 50 grant opportunities in 30+ disease areas annually to researchers across the globe, as well as within the Penn and CHOP community. Since 2011, our grant programs have funded $17.2 million in rare disease research.
 
Upcoming Grant Opportunities:
  1. The Million Dollar Bike Ride Pilot Grant Program is now open.  Click here to learn more and apply.  
  2. The Mucopolysaccharidosis Type I Pilot Grant Program is now open.   Click here to learn more any apply.
For more information about the Orphan Disease Center, visit their website.  
Spotlight on Trainees (from the August 9 issue)
Is graduate school right for me?
The Council of Graduate Schools, headquartered in Washington, D.C., is a nationwide organization dedicated exclusively to the advancement of graduate education and research. In this spirit, the CGS has prepared a short monograph, titled Graduate School and You: A Guide for Prospective Graduate Students , which aims to provide practical, straightforward advice to students who are contemplating pursuing graduate study. Last updated in 2014, the guide offers objective information on potential benefits of earning a graduate degree, the application and admissions process, and sources of financial support for graduate study. The volume is available online and also can likely be found amongst the literature in your institution's career counseling office.
Member News
Welcome to our New Members:
Antonin Bourdieu, Yale University School of Medicine
Randa Breikaa, Nationwide Children's Hospital
Jessica Hensel, UCONN Health
Rajeev Kant, Brown University
Diana Kim, Northeastern University
Sivareddy Kotla, The University of Texas MD Anderson Cancer Center
Cheryl Lee, Duke-NUS Medical School
Vihang Narkar, Univ of Texas, Health Science Center at Houston
Sarah-Anne Nicholas, UCONN Health
Patricia Nolasco, Heart Institute (InCor) - University of São Paulo
Mathilde Poulet, Yale
Kiyohito Taimatsu, NICHD/NIH
Seock-Won Youn, University of Illinois at Chicago

If you have news to share with your colleagues, send it to membership@navbo.org.
 Recent Publications by NAVBO Members

Near-Infrared IIb Fluorescence Imaging of Vascular Regeneration with Dynamic Tissue Perfusion Measurement and High Spatial Resolution
Journal of the American Heart Association
Real-time optical imaging is a promising approach for visualizing in vivo hemodynamics and vascular structure in mice with experimentally induced peripheral arterial disease (PAD).  Read more

 

Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells
Circulation Research
Human-induced pluripotent stem cell-derived endothelial cells (iPSC-ECs) have risen as a useful tool in cardiovascular research, offering a wide gamut of translational and clinical applications.  Read more

 

SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis
Nature Communications
Regulation of VEGFR2 represents an important mechanism for the control of angiogenesis. VEGFR2 activity can be regulated by post-translational modifications such as ubiquitination and acetylation.  Read more

 

Rare and Low-Frequency Variant of ARHGEF17 Is Associated With Intracranial Aneurysms
Circulation: Genomic and Precision Medicine
Intracranial aneurysms (IAs) are a group of cerebrovascular disorders characterized by irreversible dilatation or ballooning of the intracranial arterial wall.  Read more

 

Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes
Journal of Clinical Investigation
Impaired lymphangiogenesis is a complication of chronic complex diseases, including diabetes.  Read more

 

Gene expression profiles of rat MMECs with different glucose levels and fgl2 gene silencing
Diabetes Metabolism Research Reviews
BACKGROUND: Cardiac microvascular endothelial cells is one of the key factors in the process of diabetic cardiomyopathy, a common chronic complication of diabetes.  Read more

Industry News (from the August 9 issue)
New calls for papers on specialized cardiovascular topics
AJP-Heart and Circulatory Physiology , the American Physiological Society's flagship journal in the cardiovascular sciences, has issued a call for papers on special topics. Investigators are invited to submit manuscripts on topics of " Many Avenues to Cardiac Cell Death " (Guest Editors Drs. Kirshenbaum, Matsui, and Sadoshima), " Chromatin and Epigenetics in Cardiovascular Disease " (Guest Editors Drs. McKinsey and Vondriska), or " Adaptive Immunity in Cardiovascular Disease " Guest Editors Drs. DeLeon-Pennell, Halade, and Ilatovskaya). Submission deadlines range from January 31-February 15, 2019.
 
Sexual harassment in science and medicine: occurrence, costs, and countermeasures
The National Academies Press has published a Consensus Study Report, titled "Sexual Harassment of Women: Climate, Culture, and Consequences in Academic Sciences, Engineering, and Medicine," reflecting work of the Academies' Committee on the Impacts of Sexual Harassment in Academia. Over the past decades, the incidence of sexual harassment in different industries has held steady. However, as more women enter the scientific and medical workforce, more women are experiencing sexual harassment as they work and learn. The report, available for download , contains a set of recommendations aimed at countering discriminatory behavior toward women and removing barriers that can limit both their careers and the advancement of critical fields.  
 
Prenatal gene therapy advances
An international team of investigators led by Simon Waddington of University College London reports findings in Nature Medicine that raise hopes for "...prophylaxis against early, irreversible and lethal pathological change" by adapting gene therapy to use on fetal patients. The research team studied a form of Gaucher disease (nGD) associated with mutations in glucosylceramidase (Gba) . The acute childhood lethal form of nGD is untreatable since protein therapeutics cannot cross the blood-brain barrier. In a mouse Gba knockout model of nGD, fetal intracranial injection of an AAV-Gba vector reconstituted neuronal glucocerebrosidase expression and prolonged survival.
What's New at the Annual Meeting
Bioinformatics Boot Camp
Watch the webinar and see how bioinformatics can enhance your research (click on the slide to start the movie)


Attend Vascular Biology 2018 and register for this special session!
Bring your lap top and you favorite gene!!
For more information see http://www.navbo.org/events/vb2018/bootcamp
This session is filling up and has a limited attendance - register today!
 
New Venue for Vascular Biology


Vascular Biology 2018 will feature the Vascular Inflammation Workshop and the Biology of Signaling in the Cardiovascular System Workshop.  Our new venue, in Newport, RI, is Gurney's Newport Resort and Marina located on Goat Island.  Just a 10 minute walk from downtown Newport!

Plan now to attend!  Go to www.navbo.org/vb2018 for the meeting program, registration, abstract submission, award applications and more!
Job Postings
Calendar of Events
Sept. 9 - 13, 2018
11th World Congress of Microcirculation (WCM2018)
Oct. 14 - 18, 2018
Vascular Biology 2018
May 30 - June 1, 2019
Lymphatic Forum 2019
Oct. 27 - 31, 2019
Vascular Biology 2019
Sept. 9 - 12, 2020
IVBM 2020
North American Vascular Biology Organization | bernadette@navbo.org | http://www.navbo.org
18501 Kingshill Road
Germantown, MD 20874-2211