April 19, 2018
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In This Issue
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  20th IVBM   Helsinki, Finland   June 3-7, 2018
Accepting late-breaking abstracts through May 7! 


Vasculata 2018 
St. Louis, MO
July 23 - 26, 2018

Vascular Biology 
Newport, RI 
October 14-18, 2018 
Next webinar is May3
Corporate Partners
Corporate Members
VB2018 Supporters
VB2018 Exhibitors
Affiliated Journals
What's on the Web?
Trainee Awards
We support our trainee members in attending more than just NAVBO meetings - we have awards for the GRC, IVBM, Lymphatic Forum and World Congress on Microcirculation!

Go to http://www.navbo.org/awards/trainee-awards
Shop at Amazon?   
Help Support NAVBO 
Use this link to shop for everyone and everything
  smile.amazon.com/ch/52-1917956 and Amazon will donate to NAVBO 
NAVBO Webinars
Next Webinar is May 3
Chris Hughes of the University of California, Irvine, will present a webinar entitled,
A Perfused Blood-Brain Barrier on a Chip

Participation is limited to 100 attendees, register now so that you can participate in the live presentation.

For more information and to register go to: http://www.navbo.org/events/webinars/687-webinar052018 
June 14 Webinar with Juan Melero-Martin 
Join us on June 14 at 1:00pm EDT for Dr. Melero-Martin's presentation, "Engraftment of Bioengineered Vascular Networks."  Dr. Melero-Martin is an Associate Professor at Boston Children's Hospital. 

To register for the webinar please go to http://www.navbo.org/events/webinars/711-webinar062018 
Opportunities for Trainee Members
Join a Committee.  Apply for a Travel Award.
The Education Committee is looking for a new member (must be a postdoctoral fellow and a current NAVBO member).  The Education Committee has several projects in the works and our current postdoc members are hardworking and innovative!  Consider joining this vibrant committee that meets monthly via conference call. 

We are currently seeking some social media mavens for the Communications Committee - graduate students and postdoctoral fellows are most welcome to apply!  Must be a trainee member in good standing.  In addition to social media, this committee oversees the newsletter, the web site and possibly other new ways to communicate to our members.    Consider joining this committee as we seek to strengthen the vascular biology community network.

The Membership Committee is also seeking two more postdocs to participate on this committee which helps to recruit, retain and engage new members. 

To submit an application for any of these committees, go to: www.navbo.org/cte-application

Travel Awards are available for the following meetings:
Gordon Research Conference focused on Endothelial Cell Phenotypes in Health and Disease - go to http://www.navbo.org/awards/trainee-awards/travel-awards-to-grc for information.  The deadline is May 10.

World Congress on Microcirculation - go to http://www.navbo.org/awards/trainee-awards/wcm2018 for information.  The deadline is July 5.

See all the award opportunities for trainees at http://www.navbo.org/awards/trainee-awards  and don't forget scholarship applications are due for Vasculata on May 15, go to http://www.navbo.org/events/vasculata2018/2018scholarships.   
Register for Vasculata and Vascular Biology
Register for Vascular Biology and Vasculata 
Registration is now open for our annual meeting, Vascular Biology (October 14-18 in Newport, RI).  Go to www.navbo.org/vb2018

You can also register now for Vasculata 2018 (July 23-26, St. Louis, MO).  Go to www.navbo.org/vasculata.
Remember workshops fill up quickly, so register soon!
Scholarship applications are due May 15! 

You can also submit an abstract for either meeting. Go to the appropriate meeting web site.
Vascular Calcification - Call for Papers
NAVBO Research Topic on Vascular Calcification 
NAVBO has joined with Frontiers, publishers of Frontiers In Cardiovascular Medicine,and co-editors Dwight Towler, UT Southwestern Medical Center and Yabing Chen, University of Alabama, to assemble a collection of papers in the research topic of Vascular Calcification.

Please consider submitting a manuscript to the journal under this topic.  Information can be found at https://www.frontiersin.org/research-topics/7775/vascular-calcification
Spotlight on Trainees (from April 5 issue)
Healthcare Options for Graduate Students
Many academic institutions offer subsidized health insurance plans to students at affordable rates. Alternatively, students can consult the website for the Affordable Care Act, which offers guidance on the process by which grad students can seek health insurance coverage during those often lean times as a trainee and before securing full-time employment. Although the ACA has undergone changes within the last year, students not exceeding 26 years old have the option of retaining coverage under parental plans and can apply individually when aging off. Healthcare.gov advises that students shop for insurance in the state in which they are studying, where they are more likely to find plans that better align with their needs.
Lab of the Month
The Lab of Dr. Kazuyo Kegan
This month we are highlighting the lab of Dr. Kazuyo Kegan, an Assistant Professor in the Department of Anesthesiology and Critical Care Medicine, at Johns Hopkins University. Find out more about Dr. Kegan and her lab at http://www.navbo.org/membership/members-labs/705-lab042018
Lessons Learned (from the April 5 issue)
Becoming an Independent Scientist
My name is Kazuyo Kegan. I have been an Assistant Professor in the Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, since 2012. I recently received my first NIH R01 grant, which just started in December 2017.
Our institution traditionally provides no direct salary support for non-clinical faculty. Thus, the transition from junior faculty to partial dependence on mentor-initiated funding, to a combination of mentor and independent support, to finally being fully independently funded has been extremely challenging. Before reaching this point, I had to obtain multiple small internal and external funding awards. I am still in the process of building a new lab, but I hope I can share a few ideas that might be helpful and important for writing grants and becoming an independent scientist. . . .

See the complete article and other Lessons Learned at http://www.navbo.org/resources/lessons-learned.

If you would like to share your lessons learned as you moved into your role as an independent investigator, send your submission to editor@navbo.org .
Member News
Welcome to our New Members:
Zhengping Hu, Schepens Eye Research Institute
Claire Ruddiman, University of Virginia
Irina Zhevlakova, Cleveland Clinic

If you have news to share with your colleagues, send it to membership@navbo.org.
 Recent Publications by NAVBO Members

Cross-talk between blood vessels and neural progenitors in the developing brain
Neuronal Signaling
The formation of the central nervous system (CNS) involves multiple cellular and molecular interactions between neural progenitor cells (NPCs) and blood vessels to establish extensive and complex neural networks and attract a vascular supply that support their function.  Read more


Hif-1a and Hif-2a regulate hemogenic endothelium and hematopoietic stem cell formation in zebrafish
During development, hematopoietic stem cells (HSCs) derive from specialized endothelial cells (ECs) called hemogenic endothelium (HE) via a process called endothelial-to-hematopoietic transition (EHT).  Read more


Recent insights into vascular development from studies in zebrafish
Current Opinion in Hematology
Zebrafish has provided a powerful platform to study vascular biology over the past 25 years, owing to their distinct advantages for imaging and genetic manipulation.  Read more


Mir-126 is a conserved modulator of lymphatic development
Developmental Biology
Organ homeostasis relies upon cellular and molecular processes that restore tissue structure and function in a timely fashion.  Read more


Cell Phenotype Transitions in Cardiovascular Calcification
Frontiers in Cardiovascular Medicine
Cardiovascular calcification was originally considered a passive, degenerative process, however with the advance of cellular and molecular biology techniques it is now appreciated that ectopic calcification is an active biological process.  Read more


Assessing Collagen and Elastin Pressure-dependent Microarchitectures in Live, Human Resistance Arteries by Label-free Fluorescence Microscopy
Journal of Visual Expression
The pathogenic contribution of resistance artery remodeling is documented in essential hypertension, diabetes and the metabolic syndrome.  Read more


Early Heterogenic Response of Renal Microvasculature to Hemorrhagic Shock/Resuscitation and the Influence of NF-κB Pathway Blockade
Hemorrhagic shock (HS) is associated with low blood pressure due to excessive loss of circulating blood and causes both macrocirculatory and microcirculatory dysfunction.  Read more


ADAMTS9-Regulated Pericellular Matrix Dynamics Governs Focal Adhesion-Dependent Smooth Muscle Differentiation
Cell Reports
Focal adhesions anchor cells to extracellular matrix (ECM) and direct assembly of a pre-stressed actin cytoskeleton. They act as a cellular sensor and regulator, linking ECM to the nucleus.  Read more

Industry News (from the April 5 issue)
Welcome News on Federal Funding for Research
The US Congress has completed its work on a spending plan for the 2018 fiscal year, which began last October. The bill, a $1.3 trillion spending package that largely rejects deep cuts to research agencies proposed by the White House, was signed by President Trump on March 23, 2018. Analysis by AAAS indicates that the increases in research spending are the largest in over ten years. Total R&D spending is estimated to approach $180 billion, an increase of 12.8% compared to the 2017 fiscal year. The NIH will receive a $3 billion (8.3%) increase, including an additional $414 million for Alzheimer's disease research. The NSF expects a $7.8 billion (3.9%) increase.

Machine Learning in the Service of Cardiovascular Health
The Duke Clinical Research Institute (DCRI) has entered a partnership with the American Heart Association to examine the potential of machine-learning methods to successfully predict, prevent, and treat cardiovascular diseases. AHA's Precision Medicine Platform, a cloud-based data system containing cardiovascular health-related data from DCRI, private pharma, and human healthcare networks, will form the universe to be explored to improve management, access, and secondary analyses of clinical information. The two partnering organizations also will sponsor research to create new machine learning tools. 

Research Data Sharing: Challenges and Opportunities
Scientific publishing giant Springer Nature has analyzed results of a major survey of researchers about the disposition of their research data. Based on responses from nearly 8,000 scientists, Springer Nature reports that data sharing associated with published works is commonplace and that researchers are interested in making their data more readily "discoverable." A whitepaper dissecting the results of the survey addresses numerous hurdles that researchers encounter in the data-sharing process. Findings are reported globally, as well as broken down to region, subject matter, and other investigator demographic features.
Job Postings
Job Title
Oklahoma City, OK
Postdoctoral Position in Angiogenesis/Vascular biology Research
Sanford Burnham Prebys Medical Discovery Institute
St. Petersburg, FL
Brigham and Women's Hospital, Harvard Medical Shool
Boston, MA
Post Doctoral Fellow/Senior Scientist
Icahn School of Medicine at Mount Sinai
New York, NY
University of South Florida Morsani School of Medicine
Tampa, FL
Postdoctoral Research
University of South Florida Morsani College of Medicine
Tampa, FL
University of Pittsburgh
Post doc position in Mitochondrial and Vascular biology
Medical College of Wisconsin
Milwaukee, WI
Calendar of Events
April 25, 2018
NHLBI 70th Anniversary: Hearts, Spiders, and Relaxation: Voyages in Hypertrophic Cardiomyopathy
May 3, 2018
NHLBI 70th Anniversary: Understanding the Journey: The Past, Present, and Future of Cardiovascular Disease in Women
May 31 - June 1, 2018
22nd International Workshop on Vascular Anomalies
June 3 - 7, 2018
20th International Vascular Biology Meeting
June 9 - 12, 2018
XVIII International Symposium on Atherosclerosis
July 14 - 15, 2018
Endothelial Cell Phenotypes in Health and Disease (GRS)
July 15 - 20, 2018
Endothelial Cell Phenotypes in Health and Disease (GRC)
July 18 - 21, 2018
ISTH SSC 2018 Meeting
Aug. 5 - 11, 2018
13th User Training Workshop Developing Multi-Scale, Virtual Simulations with CompuCell3D
Sept. 9 - 13, 2018
11th World Congress of Microcirculation (WCM2018)
North American Vascular Biology Organization | bernadette@navbo.org | http://www.navbo.org
18501 Kingshill Road
Germantown, MD 20874-2211