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William R. Huckle, Editor
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Vascular Biology 2019
Monterey, CA
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September 9-12, 2020
Conrad Hotel Seoul
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Vascular Biology 2020
Newport, RI
October 25-29, 2020
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Help Support NAVBO
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Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes.
Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25. The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
Contact NAVBO if you have any questions or to
change your communication preferences.
Please note, you can unsubscribe to this newsletter at anytime by clicking on the SafeUnsubscribe in the footer.
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Vascular Biology 2019 - Call for Nano-Talks
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We're currently accepting Nano-Talks for presentation at Vascular Biology 2019.
These late-breaking, hot topics will be delivered in five-minute presentations consisting of five slides only. This makes for a fast-paced exciting hour of new data! If you have a great experiment or data that sheds light on a little understood area or illuminates a controversial area, AND it can be shown in 5 slides and 5 minutes, please consider participating in this session. This will be an exciting and fun opportunity to increase the exchange of ideas and concepts at VB2019!
To be considered for a Nano-Talk: 1) Register to attend VB2019, 2) Send your name, affiliation and presentation title to [email protected] and 3) include a five-slide pdf of your presentation. This pdf does not have to be the final version but we want to make sure you can present your "story" in 5 slides/5 minutes. This is critical so that the session finishes on time. Slides should NOT contain animations.
Speakers will be selected by a review committee. We will accept no more than ten speakers for this session and
submissions must be received by September 27.
The session will be presented on Monday, October 28 from 4:30-5:30pm at Vascular Biology 2019. See all meeting details at www.navbo.org/vb2019
Online registration for VB2019 is open through October 25, 2019. Although discouraged, you can register onsite as well (there will be a $35 surcharge for onsite registration).
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NAVBO Online Journal Club
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The NAVBO Education Committee is Providing an Online Journal Club for NAVBO Members
We are pleased to offer this new activity to our members! Trainees are especially encouraged to participate. Our first paper is:
Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium. Ricard N, Scott RP, Booth CJ, Velazquez H, Cilfone NA, Baylon JL, Gulcher JR, Quaggin SE, Chittenden TW, Simons M. J Exp Med. 2019 Aug 5;216 (8 ):1874-1890. doi: 10.1084/jem.20182151. Epub 2019 Jun 13. PMID: 31196980
Each Journal Club will feature a 30-minute presentation followed by a 30-minute Q&A period.
Dr. Kishore Wary, University of Illinois at Chicago, will present this first Journal Club on September 26 at 1:00pm Eastern Time. Information about the Journal Club and how to register is within the NAVBO Forum:
http://www.navbo.org/forum
Once logged in, open the topic called "Links to This Month's Paper and Presentation" and follow the link to register for the presentation. There is also a link to the paper itself. You should subscribe to this topic and
subscribe to the September 2019 Journal Club (click on the hyperlink and then choose the "subscribe" button) to receive updates.
Even after the presentation, additional comments can be posted on the forum. Simply start a new topic under the category, September 2019 Journal Club. Remember to check the box below to be notified of replies to your question or comments. Comments will be reviewed up to one month after the presentation (October 25). You can also post comments or questions prior to the presentation.
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NAVBO Continues to Bring You Exciting Webinars
Oklahoma Medical Research Foundation
Wnt/ß-catenin signaling, mechanotransduction and lymphatic vascular development
October 10, 1:00pm EDT
 And mark your calendar:
Hyung Chun
Yale School of Medicine
November 14, 1:00pm EST
Register for this meeting
NAVBO Webinars are free to current NAVBO Members. Non-members can attend for $25 per webinar.
And don't forget you can watch archived webinars as well - go to
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Promote Your Presentation on the Web Site
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Current NAVBO Members Can List Their Upcoming Presentations (Oral or Poster) on our Web Site
Keep members, and all who visit our web site, aware of presentations by NAVBO members. If you are attending the meeting, be sure to attend your NAVBO colleague's presentation. If you are also presenting at that meeting, you can attend each other's presentations and offer mutual support! It can also help make you aware when a colleague is in your town so you reach out and arrange an in-person chat. And finally, this listing can also keep you abreast of other relevant meetings and conferences.
There is a form at the bottom of the page for you to add your presentation.
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The Lab of Patrick A. Murphy
This month we are highlighting the lab of Dr. Patrick Murphy, an Assistant Professor in the Department of Cell Biology at the University of Connecticut Health Center. Pictured center, are junior scientists in training! Find out more about Dr. Murphy and his lab at
http://www.navbo.org/membership/members-labs/832-lab092019.
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Lessons Learned
(from the September 5 issue)
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Patrick A. Murphy
There is no doubt that there is a yawning gap between the postdoctoral position and the faculty position, and finding that faculty position takes foresight, determination, and also a bit of luck.
The foresight should be in finding a research trajectory that is ready to expand through some new techniques or approaches, and a PI that is able to support you in that. For those who are looking at postdoctoral positions, make sure that you talk with all of the members of the lab before you join, not just the ones the PI trots out. I chose my post-doctoral lab because the people in the lab were all happy. That is not chance. That comes from setting up a lab environment where each post-doc or student project is well separated, and being sensitive to conflicts that arise and dealing with them quickly. The ideal lab will host a variety of backgrounds and skill sets that complement each other and a PI that supports that through clear project demarcations. Your ideal PI will be able to provide you with top notch collaborators that respect your work and enhance it. So, seek someone willing to fight for you.
Once you have settled on your lab environment, you will need to be determined. My graduate PI told me once that many people have the intelligence to be a PI, but few have the grit - and I think she was absolutely right. Put in the work and start writing grants. In addition to providing focus for your science, winning grants will give you autonomy in lab that is hard to achieve in any other way. Simply put, each lab must pay the bills, and if you are paying your part, you will have a much larger say in how your part of the lab is run. I heard during my interviews and conversations afterwards, that a history of funding is a compelling case for future funding and a productive researcher, making these awards an important part of your faculty transition.
Finally, landing that faculty position will take luck. As scientists, we don't believe much in luck, but luck is another way of saying chance. The more chances you give yourself, the more likelihood you will have the outcome you seek. When I applied to faculty positions, I had an excel sheet of my contacts with institutes I thought could be a good fit. That included both open positions and cold calls. I pulled all of the strings I had, every contact I thought might be helpful, and let them know I was on the market. Even with all of that, it took two full seasons to get it right. But I did get offers, and they were from the places I felt would be the best fit for me. Luck, or chance, means you find the group of researchers you complement well, but you can put yourself in that position by working hard to find that fit. You want to hear about the position before it opens and to have put in the groundwork to know how to sell yourself as the best candidate for it.
Ok, you've made it. Suddenly there are so many open doors and research directions to follow, how do you choose? For me, it began with taking stock of my new environment, meeting as many people as possible and thinking hard about my long-term goals. Through this searching, I discovered two things that have shaped my first few years here.
First, through the foresight of my chair Linda Shapiro, I was connected to a developing project program grant (PPG) group led by Dr. Annabelle Rodriquez-Oquendo. This group brought immunologists together with human geneticists and lipid researchers. I was able to contribute as a researcher focused on endothelial cell functions and with expertise in the low flow models that drive plaque. This group has helped to bring new perspectives and lots of brain power to my own grant and paper preparations, and has resulted in the establishment of some exciting new models to assess T cell functions in the plaque microenvironment with Dr. Tony Vella, which we recently published with a review in the American Journal of Physiology. This is one of the early publications which can be so helpful for later grant applications, and would have been hard to get going so quickly without his help. The moral in this for me is that it is worth the time to find the groups in which you can have mutually beneficial relationships, and put time into those relationships. The experience of the senior researchers you meet through these interactions will be invaluable.
Second, I found we have amazing resources in flow-cytometry, single cell analysis, and sequencing. The ability to quickly get onto a sorter within minutes of deciding to run an experiment, and with the help of very talented technical assistance, allowed me to run a large set of CRISPR screens I would have otherwise hesitated to take on. This investment ultimately led to a successful AHA Innovative Project award, and is providing a basis for two NIH R01 grant submissions, and several manuscripts underway. These resources and the amount of time I have had in these cores gathering these data would have been hard to come by in many other institutes where these resources are less accessible. Find what works well near you, what gives you an edge, and take full advantage of that.
For everyone that sees this entire process as incredibly daunting and painful, it is. I hope you are as fortunate as I am to have a spouse who understands, and at least is willing to tolerate this lifestyle. It is often hard to explain that our job is also our hobby. My wife Catherine deserves more credit than I can give her here. However, for those that would be put off by the long hours and low pay through the early stages of this career, I can tell you the joy and excitement of discovering a new way to look at things, and to develop the next generation scientists, is an amazing feeling. I feel very lucky to have met the people I have in science, and to see many of them a few times a year at meetings. I've had many long conversations on the philosophy of science with my graduate mentor, Rong Wang, often at odd hours and on late night drives home. She has been incredibly helpful throughout my major career decisions, well beyond my time in her lab. I have also seen the beautiful camaraderie among the former trainees of Richard Hynes, and the respect and science ethos he has instilled in the "Hynsonians". Both are inspirations for me in establishing the type of lab that continues far beyond the walls of the institute.
See all of the Lessons Learned on our web site
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Spotlight on Trainees
(from the September 5 issue)
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Check out these creative videos - produced in the lab!
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Call for Papers - Single-Cell Analysis
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A Frontiers Research Topic initiated by NAVBO
Recent advances in analyzing tissues and organs at the single cell (SC) level are revolutionizing our understanding of organ development, biology, and disease. Previously, the genetic composition or transcriptional profiles of cells was based on sequencing DNA or RNA from a large number of cells, but this approach loses information on the heterogeneity of individual cells. Sequencing DNA and RNA from individual cells preserves heterogeneity, and technological advances have made these techniques highly accessible.
A recent analysis - available
here - of the SC extramural research funded by the NIH, either through NIH-initiated programs focused on SC or initiated by extramural investigators, revealed the paucity of such analyses related to vascular cells compared to a variety of other cells and tissues. This Research Topic is seeking to galvanize interest in SC applications related to the field of vascular cell biology and highlight original research related to SC analyses of vascular related cells, under normal or diseased conditions. We seek to understand the specific challenges associated with studying vascular cells, and how advances in SC approaches could benefit vascular fields. Submissions are due September 30, 2019.
More information can be found here on the Frontiers web site.
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Welcome to our New Members:
Jasimuddin Ahamed, Oklahoma Medical Research Foundation
Kevin Boyé, Yale University
Woosoung Choi, Gwangju Institute of Science and Technology
Daniel Howsmon, The University of Texas at Austin
Alex Khang, The University of Texas at Austin
Austin Lansing, Queen's University
Feifei Li, Emory University
Stephanie Lindsey, Stanford University
Lindsey Olivere, Duke University School of Medicine
Saravana Ramasamy, Imperial College London
Kayla Schroer, University of California San Francisco
Erica Schwarz, Stanford University
Jeremy Wong, University of Toronto
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Industry News (from the September 5 issue)
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Illuminating the Druggable Genome
There is a new NIH funding opportunity related to their initiative,
Illuminating the Druggable Genome" (IDG), that enables discovery of new targets among the less know proteins. IDG has funded the creation of the Pharos bioinformatics tool (presented at the previous NAVBO meeting boot camp). In this case, pilot project funding will be awarded to support the generation of additional data and tools around understudied protein(s) identified by the IDG Program to elucidate the function of these proteins in the context of human disease.
Important dates:
Open Date (Earliest Submission Date) September 28, 2019
Letter of Intent Due Date(s) September 28, 2019
Application Due Date(s) October 28, 2019, by 5:00 PM
Full announcement:
All questions should be addressed to the Scientific/Research Contact(s): Karlie Sharma, Ph.D.
National Center for Advancing Translational Sciences (NCATS)
Telephone: 301-451-4965
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Partner Network Advantage on the NAVBO Job Board
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Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
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Be inspired!
