May 16, 2019
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Vascular Biology 
Monterey, CA  

Lymphatic Forum 2019
Austin, TX
May 30 - June 1, 2019
You can still register!

Vasculata 2019
Medical College of Wisconsin
July 13 - 18, 2019

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Affiliated Journals
Partner Network Advantage - New Job Board Feature
Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
 
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
 
Post your open position now at www.navbo.org/jobs! 
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Help Support NAVBO 
NAVBO Privacy Policy
Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes. Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
 
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25.   The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
 
Contact NAVBO if you have any questions or to change your communication preferences.
 
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*Product News is a paid advertising space. For more information go to: http://www.navbo.org/images/MediaKit-NewsBEAT.pdf
Call for Nominations - Meritorious Awards
Seeking nominations for the Judah Folkman and Earl P. Benditt Awards.
These are NAVBO's most prestigious honors, and each one reading this knows of several colleagues who are deserving of one of these honors.

The Earl P. Benditt Award recognizes an individual who has made an outstanding discovery or developed a concept that has been seminal to our understanding of vascular biology or pathology. More information is available here: http://www.navbo.org/awards/earl-p-benditt-award

The Judah Folkman Award in Vascular Biology is a mid-career award and, in recognition of the breadth of Dr. Folkman's interests and his many contributions to vascular biology, is not limited to the field of angiogenesis, instead encompassing the full range of original research in vascular biology. The recipient will have made a significant impact on the field through his/her original research accomplishments. Information can be found here: http://www.navbo.org/awards/judah-folkman-award

The submission deadline is July 8. Please honor your colleagues by nominating them for one of these prestigious awards. http://www.navbo.org/awards/nominations-for-meritorious-awards
Seeking Postdoctoral Fellows for Education Committee
The Education Committee is looking for postdoctoral fellows to join the committee. This is your opportunity to make a difference by enhancing the trainee member's experience, network with a great group of scientists, and gain leadership experience with this great organization! If you're interested in joining us, please apply today!

Applicants should expect to serve a three-year term. Applications must include: your CV, a letter from your supervisor attesting to your leadership quality, a brief statement from you concerning your commitment to the vascular biology community and this society, and what you would like to bring to this committee. Please forward this information to ( [email protected]) by June 14, 2019.

If you have further questions about the Education Committee or the application process, please feel free to contact Bernadette ( [email protected]) or Mary Jo Mulligan-Kehoe, the Committee Chair ( [email protected]).
June Webinar with Daniel Greif
Pericyte ALK5/TIMP3 Axis Contributes to Endothelial Morphogenesis in the Developing Brain
Join  us on June 13 - at 1:00pm EDT for a webinar featuring Dr. Daniel Greif of Yale University.  His presentation will reveal a key role for PC ALK5 in regulating brain endothelial morphogenesis and a substantial therapeutic potential for TIMP3 during GMH-IVH.  

For more details and to register go to: http://www.navbo.org/events/webinars/807-web062019
 
NAVBO Webinars are free to current NAVBO Members.

Don't Miss These Upcoming Webinars:
July 11 - Kishore Wary, University of Illinois at Chicago
August 8 - Vicki Bautch, University of North Carolina at Chapel Hill 
 
And don't forget you can watch archived webinars as well - go to  
"Shadow Labs"
Crackdown on "shadow labs" by universities and the NIH underway
Jocelyn Kaiser reports in Science (April 11, 2019) that a day of reckoning is coming for NIH-funded investigators who have been complicit in efforts by foreign governments to take unfair advantage of US federally-sponsored research. In response to Senate Appropriations Committee Chair Roy Blunt's inquiries about initiatives to enforce compliance by grantees with rules on revealing foreign ties, protecting intellectual property, and resisting offers to set up "shadow labs" overseas, NIH Director Francis Collins noted that NIH is "deeply concerned" about the mounting evidence for such abuses. Investigations of foreign scientists funded by the NIH are in progress at nearly 60 U.S. institutions, the results of efforts to root out "double dipping," or the failure to disclose foreign funding for work being simultaneously supported by NIH. Collins indicated that the heightened scrutiny and enforcement will lead in some cases to dismissals and possibly the return of international investigators to their countries of origin.
[ Thanks to NAVBO Councilor Jan Kitajewski and Research!America for bringing these matters to our attention. -ed.]
Vasculata 2019 - Register Today!
Vasculata 2019 - July 15-18 
Medical College of Wisconsin
Join us in Milwaukee this summer for the 15th Vasculata. Check out the exciting preliminary program!!  Scholarships are available, there are several hands-on workshops, keynote talks by Luisa Iruela-Arispe and Curt D. Sigmund, selected abstracts will be chosen as short talks (also new) and of course poster sessions and lectures. Go to http://www.navbo.org/events/vasculata2019 for more information.

Register today (early bird deadline is June 3) -
Submit your abstract (deadline is June 3) -
Call for Papers - Single-Cell Anaylysis
A Frontiers Research Topic initiated by NAVBO
Recent advances in analyzing tissues and organs at the single cell (SC) level are revolutionizing our understanding of organ development, biology, and disease. Previously, the genetic composition or transcriptional profiles of cells was based on sequencing DNA or RNA from a large number of cells, but this approach loses information on the heterogeneity of individual cells. Sequencing DNA and RNA from individual cells preserves heterogeneity, and technological advances have made these techniques highly accessible.

A recent analysis - available here - of the SC extramural research funded by the NIH, either through NIH-initiated programs focused on SC or initiated by extramural investigators, revealed the paucity of such analyses related to vascular cells compared to a variety of other cells and tissues. This Research Topic is seeking to galvanize interest in SC applications related to the field of vascular cell biology and highlight original research related to SC analyses of vascular related cells, under normal or diseased conditions. We seek to understand the specific challenges associated with studying vascular cells, and how advances in SC approaches could benefit vascular fields. More information can be found here on the Frontiers web site.
Product News*
Introducing ACS Pharmacology & Translational Science

ACS Pharmacology & Translational Science
 is a new journal from the American Chemical Society publishing high-quality, innovative research across the broad spectrum of biological sciences.
 
Read Volume 2, Issue 1, free courtesy of ACS Publications.  
 
 
 
And don't miss NAVBO member Professor Kathleen M. Caron's latest work in our Articles ASAP.
Lymphatic Forum 2019
AustinBrightNight
Register today -
online registration closes May 29!  
 
For all meeting info, go to www.navbo.org/lymphatics2019
Lessons Learned
Cindy St. Hilaire
My name is Cindy St. Hilaire, and I'm an Assistant Professor in the Departments of Medicine and Bioengineering at the University of Pittsburgh and a member of the Pittsburgh Heart, Lung, and Blood Vascular Medicine Institute. My lab was established in July 2015 after my postdoctoral fellowship at the NHLBI, and these last 3.5 years have been both the most rewarding as well as the most challenging of my professional life; starting your lab is an exciting yet surreal experience. You'll be called upon to develop and master skills that have little relation to your previous training, and in the first few years resolving that main conundrum will reveal many of your hidden character strengths and weaknesses. I hope sharing my experiences thus far can help a fellow new PI.
  
Picking the right place - You really need to define for yourself what circumstances will create your ideal environment, what circumstances are less than ideal but workable, and what conditions constitute a deal-breaker. Obviously, having the tools, cores, and resources that you need to conduct your research are essential, but those alone will not guarantee your scientific success or happiness. Consider the one-on-one meetings during interviews as a two-way street; yes, they are interviewing you, but you need to interview them as well. Do not be afraid to ask questions that will help you determine if the institution is a right fit for you. Ask about life outside the lab, where do people live? What do they do outside of work? How good/bad is the commute? Besides talking about science, can you see yourself having coffee or lunch with the people in your department? Or doing social activities? Do them seem enthusiastic or stressed? Competitive or collaborative? Very important: does the department have a solid history of fostering young PIs through to tenure, or is there a suspiciously high failure rate? Are people smiling in the hallways or do they stare at their feet as they walk by? Academic departments and institutes have pretty defined cultures, and they can vary widely from school to school, make sure the one you join is a culture that suits you.
  
Click here to read about what Dr. St. Hilaire has to say about Setting up Shop, Staff & Students, Saying YES, Building a support/mentoring team and Figuring out what works for you!
Lab of the Month
The Lab of Delphine Gomez

This month we are highlighting the lab of Dr. Delphine Gomez, an Assistant Professor in the Department of Medicine at the University of Pittsburgh. Find out more about Dr. Gomez and her lab at  http://www.navbo.org/membership/members-labs/806-lab052019.  
Spotlight on Trainees (from the May 2 issue)
Pre-med track draws but cannot always retain women interested in medical careers 
Female high school students express more interest in medicine than do their male peers. Moreover, young women earn better high school grades and more frequently attend college. Discouragingly, this trend blunted by what is described as the "gendered nature" of attrition in pre-med science courses, according to a study recently published in Educational Researcher. Investigators parsed the academic records of more than 8,250 pre-med students enrolled in typical pre-med courses between 2008 and 2016 at a large, public four-year institution. The study revealed that women were more likely to drop out of the pre-med track, even when earning the same high grades as their male peers. The study's authors suggest that academic performance was not the biggest deterrent for women, but other factors, perhaps a lack of confidence in their abilities, contributed to the higher rates of abandoning the medical school trajectory.
Summer Training for Junior Faculty
Programs to Increase Diversity Among Individuals Engaged in Health-Related Research
The NHLBI PRIDE Program is offering nine unique Summer Institute programs with intensive mentored training opportunities to enhance the research skills and to promote the scientific and career development of trainees. Trainees will learn effective strategies for preparing, submitting and obtaining external funding for research purposes, including extensive tips on best practices. Trainees will also be able to apply for small grants to support mentored-pilot research projects. Research emphasis varies by program.
   
Eligible applicants are junior-level faculty or transitioning postdoctoral scientists with background deemed under-represented in the biomedical or health sciences. Research interests should be compatible with those of the National Heart, Lung, and Blood Institute (NHLBI) in the prevention and treatment of heart, lung, blood, and sleep (HLBS) disorders.   
 
Of particular interest to NAVBO members are the programs on Cardiovascular Disease Comorbidities, Genetics and Epidemiology (CVD-CGE) (July 17-31, 2019) and Cardiovascular Health-Related Research (CVD) (July 7-19, 2019).
 
Apply early - there are a limited number of positions and admission will close when spaces are filled. 
 
Visit the web site at https://pridecc.wustl.edu
Member News
Welcome to our New Members:
Javier Abello, Washington University
Benjamin Gordon, University of Illinois Chicago
Valeria Orlova, Leiden University Medical Center
Qanber Raza, University of Illinois at Chicago

If you have news to share with your colleagues, send it to [email protected]
 Recent Publications by NAVBO Members

Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome
Nature Communications
Potentiation of neutrophil extracellular trap (NET) release is one mechanism by which antiphospholipid antibodies (aPL Abs) effect thrombotic events in patients with antiphospholipid syndrome (APS).  Read more

 

High mitogenic stimulation arrests angiogenesis
Nature Communications
Appropriate therapeutic modulation of endothelial proliferation and sprouting is essential for the effective inhibition of angiogenesis in cancer or its induction in cardiovascular disease. The current view is that an increase in growth factor concentration, and the resulting mitogenic activity, increases both endothelial proliferation and sprouting.  Read more

 

Myocardial differentiation is dependent upon endocardial signaling during early cardiogenesis in vitro
Development
The endocardium interacts with the myocardium to promote proliferation and morphogenesis during the later stages of heart development. However, the role of the endocardium in early cardiac ontogeny remains under-explored.  Read more

Industry News (from the May 2 issue)
USDA Research Arm to Eschew Use of Cats as Experimental Subjects
The US Department of Agriculture's Agricultural Research Service has decided to discontinue the use of cats in all ARS research. As reported by the National Association for Biomedical Research (NABR), the ARS has been the target of an extended animal rights campaign waged by the White Coat Waste Project. Among other projects, the ARS has long studied transmission and pathophysiology of toxoplasmosis in cats. NABR is also following a proposed rule by the USDA's Animal and Plant Health Inspection Service to modify requirements for licensing in research using dogs.

HHS and NIH Leaders Testify to Congress on Biomedical Research Funding
Members of the senior NIH leadership, including Director Francis Collins and five institute directors, appeared on Capitol Hill April 2 to testify before the House Appropriations Labor-HHS Subcommittee.  At issue was the president's proposed FY2020 budget, which calls for cuts in the NIH budget characterized by House members as out of step with Subcommittee's bipartisan support of medical research. Two days later, the Senate Labor-HHS Subcommittee heard budget-related testimony from HHS Secretary Alex Azar. More details are available in the AAMC's Washington Highlights.

Stable Cardiovascular Mortality in States that Expanded Medicaid
The expansion of Medicaid occurring under the Affordable Care Act (ACA) has been associated with reduced deaths attributable to cardiovascular disease. A study, reported in MEDPAGE TODAY and using data from a Centers for Disease Control mortality database, indicated that cardiovascular mortality rates among middle-age adults was stable in states opting for Medicaid expansion, while mortality increased in non-expansion states (176.3 to 180.9 deaths per 100,000 residents per year; P=0.001). The biggest impact in cardiovascular deaths was found in non-metropolitan counties and in areas with the most residents living in poverty.
Job Postings
Calendar of Events
May 30 - June 1, 2019
Lymphatic Forum 2019
June 12 - 16, 2019
13th HHT International Science Conference
June 22 - 25, 2019
ASMB Workshop 2019 - Fibroblasts: the Arbiters of Matrix Remodeling
July 6 - 10, 2019
International Society on Thrombosis and Hemostasis Congress 2019
July 21 - 26, 2019
GRC - Elastin, Elastic Fibers, and Microfibrils
Oct. 27 - 31, 2019
Vascular Biology 2019
North American Vascular Biology Organization | [email protected] | http://www.navbo.org
18501 Kingshill Road
Germantown, MD 20874-2211