October 27, 2016 
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In This Issue

NAVBO members receive discounts on registration to IVBM 2016
Look inside the IVBM Virtual Conference Bag

Lymphatic Forum
in Chicago, IL
June 8-10, 2017

Vascular Biology 2017
Monterey, CA
October 15-19 

Vasculata 2017

Chicago, IL
August 7-10, 2017
Corporate Partners
Corporate Members
Affiliated Journals
IVBM Supporters
Diamond Level
Welcome Reception Host

Gold Level

Strategic Partners

Meet the Professor Breakfasts Supported by

  Event Partners

Gold Level
Academic Supporter
Silver Level
Academic Supporters


Bronze Level
Academic Supporters


Online Registration for IVBM Closes Tomorrow!
19th International Vascular Biology Meeting 
Boston - October 30-November 3
Register online by October 28 to save $$ 
There will be onsite registration available, but there will be a late fee of $50.

Additional information about child care, traveling around Boston, etc. can be found here: http://www.ivbm2016.org/hotel
Lab of the Month
The Lab of Dr. Daniela Simona Ardelean

This month we are highlighting the lab of Dr. Daniela Simona Ardelean of the University of Western Ontario. Find out more about Dr. Ardelean's lab at  http://www.navbo.org/membership/members-labs/541-lab102016.

Member News
One Brave Idea
Congratulations to Dr. Calum MacRae, chief of Cardiovascular Medicine at Brigham and Women's Hospital, who is the recipient of the "One Brave Idea Research Award" to support his visionary approach to understanding and addressing coronary heart disease (CHD) and its devastating consequences.  Nancy Brown, CEO of the American Heart Association said, "Dr. MacRae and his newly-formed, world-renowned, multidisciplinary team were selected from
 among hundreds of applicants throughout the world to receive this landmark award that will provide support over a five-year period for a research project focused on uncovering the causes of heart disease, including previously unrecognized signals marking the transition from we llness to the earliest, yet still largely invisible stages of disease."   The award is sponsored by AHA, Verily Life Sciences and Astra-Zeneca.  Read more 
Welcome our new members:
Karina Gasbarrino, McGill University
Alison Kitajewski, UIC
Yoo-wook Kwon, Seoul National University Hospital
Solomon Mensah, Northeastern University
Anahita Mojiri, University of Alberta
Babak Razani, Washington University
Junchul Shin, Temple University
Jinling Yang, Boston University

If you have news to share with your colleagues, send it to membership@navbo.org.
Spotlight on Trainees
Congratulations to our IVBM Travel Award Recipients!

The Japanese Vascular Biology and Medicine Organization
Katsuya Honda, Kyushu University
Hiroyasu Kidoya, Osaka University
Nako Maishi, Hokkaido University
Takuro Miyazaki, Showa University School of Medicine
Fumitaka Muramatsu, Osaka University
Masashi Muramatsu, Kumamoto University
Sachiko Nishimoto, Tokushima University Graduate School
Keisuke Omori, University of Tokyo
Masahide Sakabe, University of Cincinnati
Tomohisa Sakaue, Ehime University

European Vascular Biology Organization
Koval Smith, Imperial College London
Robert Szulcek, VU University Medical Center

Edwards LifeScience Center for Advanced Cardiovascular Technology with The University of California, Irvine
Jurjan Aman, VU University Medical Centre
Linden Green, Indiana University
Chin Yee Ho, Kings College London
Sungwoon Lee, Yonsei University

Nature Communications
Xuan Jiang, University of California, San Francisco

Graduate Students
John-Michael Arpino, Robart's Research Institute, Western University
Stephanie Bonney, University of Colorado Denver - AMC
Brittany Durgin, University of Virginia
Sergio Esteban, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC)
Kevin Kruse, University of Illinois at Chicago
Austin McDonald, UCLA-Caltech Medical Scientist Training Program
Amanda Pellowe, Yale University
Matthew Siviski, Maine Medical Center Research Institute
Pascal Yazbeck, University of Illinois Chicago

Postdoctoral Fellows
Miranda Good, University of Virginia
Enis Kostallari, Mayo Clinic
Andrew Kuo, Yale University
Callie Kwartler, University of Texas Health Science Center at Houston
Chin Nien Lee, Boston Children's Hospital
Laura Pisarsky, Fred Hutchinson Cancer Research Center
Dario Riascos-Bernal, Albert Einstein College of Medicine
Masahiro Shin, Univ of Massachusetts Medical School

Merit Award
Amber Stratman, NICHD/NIH
 Recent Publications by NAVBO Members

Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia
Journal of Cell Biology
Morphogenesis of the vascular system is strongly modulated by mechanical forces from blood flow. Hereditary hemorrhagic telangiectasia (HHT) is an inherited autosomal-dominant disease in which arteriovenous malformations and telangiectasias accumulate with age. Most cases are linked to heterozygous mutations in Alk1 or Endoglin, receptors for bone morphogenetic proteins (BMPs) 9 and 10.  Read more


Interaction between integrin a5 and PDE4D regulates endothelial inflammatory signalling
Nature Cell Biology
Atherosclerosis is primarily a disease of lipid metabolism and inflammation; however, it is also closely associated with endothelial extracellular matrix (ECM) remodelling, with fibronectin accumulating in the laminin-collagen basement membrane. To investigate how fibronectin modulates inflammation in arteries, we replaced the cytoplasmic tail of the fibronectin receptor integrin a5 with that of the collagen/laminin receptor integrin a2.  Read more


Hydrogen sulfide therapy in diabetes-accelerated atherosclerosis: a whiff of success
Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in diabetes (1). Atherosclerosis occurs earlier and with greater severity in the population with diabetes, leading to a much higher risk of myocardial infarction, stroke, and limb ischemia and amputation.  Read more

Plan to Attend - Exhibitor Showcases at the IVBM
Exhibitor Showcases at the IVBM - Boston

Monday, October 31 from 5:15-6:15pm
Protocols for Measuring Endothelial Barrier Function with ECIS
(from TEER across transwell filters to large scale screens on 96 well plates)
Presentation by Dr. Christian Renken, Applied BioPhysics

Wednesday, November 2 from 4:00-5:00pm
Cellular Heterogeneity in Cardiovascular Disease: Exploring Mechanisms through Single Cell Analysis  
Presentation by Julius L. Decano, Brigham and Women's Hospital, Harvard Medical School 

Monday, October 31 from 4:00-5:00pm
Targeted proteomics performed on the Q Exactive permits to study the metabolism of circulating apolipoproteins
Sasha A. Singh, Director of Proteomics Center for Interdisciplinary Cardiovascular Sciences Brigham and Women's Hospital, Boston, MA
Translational Proteomics Workflows for Extending the Profiling Range of Plasma/Serum
Scott Peterman and David Sarracino Thermo Fisher Scientific BRIMS, Cambridge, MA
Tuesday, November 1 from 4:00-5:00pm 
Unlocking Translational Biomarkers in Vascular Biology with Ultra High Frequency Ultrasound 
Presentation by Dr. Julius Decano, Brigham and Women's Hospital 
Industry News
Is Faith in Our Research Antibodies Well-placed?
As reported on NPR , a recent meeting of the Global Biological Standards Institute (GBSI) in conjunction with The Antibody Societyexamined industry standards and practices intended to assure the reliability of antibodies used in basic and clinical research. Several high-profile examples of the collapse of promising diagnostic or therapeutic applications of antibodies have brought the issue into the foreground of discussions about reproducibility of research findings. While the GBSI conference focused on the production side of the equation, we scientists at the bench are wise to remember that the burden of validation ultimately lies upon us, and that our attention to potential cross-reactivity, batch-to-batch variability, and altered analyte integrity can spare us disappointment...or worse.
Facebook Founder's Philanthropic Foray
Mark Zuckerberg cannot be accused of setting modest goals. Zuckerberg and his wife, Dr. Priscilla Chan, have posed the question, "Can we cure, prevent or manage all disease by the end of this century?" and pledged $3 billion to answer it . Writing in The Guardian, commentator Celine Gounder notes that, although the gift is large and the goal worthy, the amount is but a fraction of that spent via the NIH budget annually toward the same end. Moreover, systemic obstacles exist in the form of a decentralized scientific community conditioned to be risk-averse by the highly competitive nature of the quest for continued funding. The Chan Zuckerberg Initiative seeks to create new forms of cross-institutional collaboration and apply cutting-edge informatics technology to break down cultural barriers and reveal new horizons.
Early Career Award Opportunity
The American Physiological Society invites applications for the Arthur C. Guyton Award for Excellence in Integrative Physiology . This ~$30,000 award is intended to support an APS member who is an independent investigator holding an academic rank no higher than Assistant Professor and is pursuing research that utilizes quantitative and integrative approaches and feedback control system theory for the study of physiological functions. Deadline to apply is November 13, 2016. Recent awardees have included investigators in vascular biology.
Job Postings
Job Title
Stanford University
Palo Alto, CA
Acute Care Nurse Practitioner
University of Virginia Health System
Charlottesville, VA
Calendar of Events
Oct. 28 Brigham and Women's Hospital Vein Graft Symposium
Oct. 30 - Nov. 3 19th International Vascular Biology Meeting
Nov. 13-16 American Society for Matrix Biology Biennial Meeting
June 8 - 10 Lymphatic Forum 2017
Oct. 15-19 Vascular Biology 2017
Collaborating Societies at the IVBM

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