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William R. Huckle, Editor
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Join 250 of your colleagues who have already registered!
Vascular Biology 2020
An exciting virtual event
October 26-29, 2020
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Boston, MA
Postponed until Summer 2021
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Vascular Biology Publications Alert Now Available by Subscription
The NAVBO Vascular Biology Publications Alert will now be available to non-members for a $55 a year subscription. If you would like to receive this alert, but are not a member, please contact Danielle at membership@navbo.org.
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Partner Network Advantage on the NAVBO Job Board
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Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
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Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes. Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25,2018. The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
Contact NAVBO if you have any questions or to change your communication preferences.
Please note, you can unsubscribe to this newsletter at anytime by clicking on the SafeUnsubscribe in the footer.
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Today's Webinar
 Today's webinar, September 17 at 1:00pmET, will feature Dr. Suneel Apte, of the Cleveland Clinic, and his presentation on Aggregating proteoglycans in the vascular wall - Implications for normal function, disease and phenotype modulation. Vascular wall composition and structure has an important role in vessel biomechanics at the tissue level and also in cell regulation. Proteoglycans, which are protein core + glycosaminoglycan composites, contribute vital structural properties to vessel extracellular matrix and have important regulatory roles vis-à-vis vascular cells. Proteoglycans that form aggregates with hyaluronan constitute a special class with unique attributes. This presentation will review their roles in vascular function and pathology illustrated by recent work from his laboratory.
Next Week's Journal Club
Join us on September 24 at 1:00pmET for this month's Journal Club, featuring: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination. Nature Communications 07 Aug 2020. You can review the paper at: https://www.nature.com/articles/s41467-020-17740-1#citeas. Lisandra Vila Ellis, MD Anderson Cancer Institute, a member of the NAVBO Education Committee, will give a 30-minute presentation followed by a 20-30 minute discussion. William Hughes, Medical College of Wisconsin, also of the Education Committee, will moderate the session. To register for this Journal Club, go to https://www.navbo.org/forum/09-20journal-club
Upcoming Webinars:
Due to Vascular Biology 2020, we will not be holding an October webinar. Join us in November for a webinar by Hellmut Augustin, Heidelberg University and German Cancer Research Center, titled, "Vascular Control of Tumor Progression and Metastasis."
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Thrombosis and Haemostasis
Thrombosis and Haemostasis provides a forum for the exchange of ideas and concepts fostering cross-disciplinary insights in basic and clinical research. The journal is published monthly in print and online via Thieme E-Journals.
It is covered in the main abstracting and indexing services and has an impact factor of 4.379.
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Poster Discussions at Vascular Biology
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Get Excited about Vascular Biology 2020!
In addition to our regular schedule, we are sponsoring several types of interactive sessions: Poster Discussions, Round Tables, Meet-the-Professor/Ask Me Anything, and Evening Discussions (especially for colleagues in Asia and Australia) PLUS all attendees will have the capability of entering their own private breakout sessions. Our exhibitors will also be available for meetings and you can visit their virtual booths at scheduled times or make appointments with them. In this week's newsletter, let's take a closer look at the Poster Discussions.
What is a Poster Discussion?
Well, I'm sure you know the answer to that, but at Vascular Biology 2020, a Poster Discussion will:
- have six participating poster presenters
- each presenter will give a one-minute recap (we encourage/recommend attendees visit the ePosters prior to the sessions - ePosters will be available to meeting attendees from October 12)
- have two expert moderators leading a lively discussion
- take place from 12:45-1:45pmET on Tuesday and Wednesday, October 27 & 28
- NOT be recorded in order to encourage uninhibited questions as well as discussion of unpublished data; so plan to attend
We are currently planning eight Poster Discussions! Find out about our Round Tables in the next issue of the NewsBEAT
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We are very excited to be joined by: The Microcirculatory Society and the
American Society for Investigative Pathology
The preliminary program/schedule is available at
but we will be adding Poster Discussions and Round Tables soon!
Tweet this! Register for Vascular Biology 2020 |
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Grant Opportunity in Lymphatics
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Funding Opportunity for Lymphatic Malformations
The Lymphatic Malformation Institute and Lymphangiomatosis & Gorham's Disease Alliance are pleased to announce that the 2020 Million Dollar Bike Ride Pilot Grant Program is now open!
There is one $81,965 grant available for basic science and/or clinical research on generalized lymphatic anomaly (GLA), Gorham-Stout Disease (GSD), kaposiform lymphangiomatosis (KLA), and central conducting lymphatic anomaly (CCLA).
This Request for Applications (RFA) is open to the international community. All individuals holding a faculty-level appointment at an academic institution or a senior scientific position at a non-profit institution or foundation are eligible to respond to this RFA.
For more details about this grant program, please visit the ODC website.
Letters of Interest (LOIs) are due no later than Friday, September 18, 2020 by 8 pm EDT.
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Restructuring of Study Sections
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NIH CSR begins implementation of ENQUIRE 2019 findings to modify study sections
Last year, the Center for Scientific Review at the NIH undertook Evaluating Panel Quality in Review (ENQUIRE 2019). This process aimed to ensure that study sections have the capacity to adapt their focus and priorities as their areas of science change. Over the past year, CSR ENQUIRE has integrated data and input from multiple stakeholders to determine whether changes in study section scope are needed to facilitate the identification of high impact science, with special consideration of emerging topics. Ten existing study sections of high interest to NAVBO members, clustered under the Cardiac, Vascular and Hematologic Sciences heading, have been reorganized into eight new groups, including Basic Biology of Blood, Heart and Vasculature (BBHV), Integrative Vascular Physiology and Pathology (IVPP), and Atherosclerosis and Vascular Inflammation (AVI). Reviews by the IVPP panel, which will consider applications focused on endothelial cells, blood vessels and lymphatics and their role in normal physiology and disease, will commence with the Oct 5, 2020, grant deadlines (Feb/March 2021 review meetings).
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Bhama Ramkhelawon 
I am thankful to NAVBO for giving me the opportunity to share my experience with you in this column. I invite early career fellows to read theses sections from all the past contributors. They are REAL lessons learned.
I feel it is worth mentioning that I write these words in August 2020 during the unfortunate COVID-19 pandemic that struck us with a pounding weight and burdened us with many uncertainties for the future. There have been may lessons learned from this pandemic. Decisions were made based on observation and data collected during the initial wave of infections. As we gathered more evidence, we became more familiar with the mode of infection and contamination of the SARS-CoV-2 virus. We were then able to refine treatment of patients and make more informed decision to the general public.
This scenario will most likely portray the journey of a junior to a senior scientist. There will be many first times seasoned with complex choices, round-abouts, painful moments, rejections, but as hard as all these seem to be in the beginning, with careful observation, patience and resilience, you will eventually have "Veni, Vidi, Vici" as your motto.
My colleagues have all provided valuable insights into measures to adopt to trace a successful trajectory as an independent investigator. I would like to take this space to share new perspectives in this spectrum of initiatives that provide guidance and encourage opportunities.
Dr. Ramkhelawon emphasizes "Professional personality" etiquette, organization, trust in your results, and being thankful as specific points to consider. Read her full article on our website.
You can view all of the Lessons Learned by visiting our web site. Go to
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The Lab of Dr. Bhama Ramkhelawon
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Spotlight on Trainees (from September 3 issue)
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Funding opportunity to support undergraduate research
Cayman Biomedical Research Institute (CABRI), a nonprofit affiliate of specialty biochemical supplier Cayman Chemical that supports research on rare illnesses and orphan diseases, is soliciting applications from undergraduate students who have been offered an unpaid laboratory research position under an accredited principal investigator. CABRI's program is motivated by the recognition that research positions available to undergraduates typically are unpaid, limiting access to students who can afford to volunteer their time. Kirk Maxey, President and CEO of Cayman and President of CABRI, notes that the grants are "...intended to expand access to this opportunity for more individuals whose early research training will set them on a lifelong path of scientific discovery." Applications will be accepted until September 20, 2020, for awards to be distributed by November 2, 2020. Grants from CABRI will range from $2,000-5,000 and may be awarded as individual or group grants.
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September 18 Seminar
Join NAVBO Member, Kathleen M. Caron, Professor & Chair at the Dept. of Cell Biology & Physiology, University of North Carolina, Chapel Hill for her seminar, G Protein-Coupled Receptor Pathways in Lymphatic Growth and Function, which is part of the Regenerative Biology & Stem Cells Seminar Series organized by NAVBO member, Guillermo Oliver of Northwestern University. Dr. Oliver will host this session.
Join Dr. Caron on Friday, September 18, 2020 from 12:00pm to 1:00pmCT via this link:
Meeting ID: 964 3310 9698
Passcode: 676195
For a complete schedule of seminars in this series, go to:
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Seminars in Vascular Biology
 Several NAVBO members: Peter Libby, Michael Gimbrone, Masanori Aikawa, Guillermo Garcia-Cardena, and Patricia D'Amore are members of a Seminars in Vascular Biology planning committee at Harvard Medical School.
Today's lecture at 4:30pmET is the Ramzi S. Cotran Memorial Lecture:
The Endothelial Cell by Elazer Edelman.
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Welcome to our New Members:
Johnathan Abou-Fadel, Texas Tech University Health Sci Center El Paso
Danielle Alfano, Washington University School of Medicine
Typhaine Anquetil, INSERM
Janine Arts, Sanquin
Tove Bekkhus, Uppsala University
Yun Hwa Choi, University of Wisconsin - Madison
Ying Ying Julia Chu, The Uhniversity of Edinburgh
Chinwe E-Amankwah, UIC
Shentong Fang, Wihuri Research Institute and University of Helsinki
Ahana Gupta, University of Illinois at Chicago
Laurent Jacob, Inserm U970-PARCC
Jing Ju, Virginia Tech
Emily Juzwiak, Johns Hopkins University
Mohamad Kassab, Massachusetts General Hospital
Amy Kimble, UCONN Health
Jun-ichiro Koga, Kyushu University
Franzi Krautter, University of Birmingham
Luc Krimpenfort, University of Amsterdam
James Lemon, Harvard University
Veli-Matti Leppänen, Wihuri Research Institute
Adrien Lupieri, Center for Interdisciplinary Cardiovascular Sciences
Bryan MacDonald, Broad Institute of MIT and Harvard
Sahana Manohar-Sindhu, University of Florida
Stefan Milutinovic, Cardiff University
Agnes Noel, ULIEGE
Adjanie Patabendige, University of Newcastle
Mahima Reddy, University of Virginia
Serena Russell, Draper
Brian Sansbury, Harvard Medical School/Brigham and Women's Hospital
Ligia Simoes Braga Boisserand, Yale University
Sonja Vermeren, The University of Edinburgh
Ivan Fan Xia, Yale University
Yi Xing, Boston University
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| Recent Publications by NAVBO Members |
Characterization of ANGPT2 mutations associated with primary lymphedema
Science Translational Medicine
Background: Impaired lymphatic drainage of the arterial wall results in intimal lipid accumulation and atherosclerosis. However, the mechanisms regulating lymphangiogenesis in atherosclerotic arteries are not well understood. Read more
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Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation
Critical Care Explorations
Objectives: Coronavirus disease 2019 is caused by the novel severe acute respiratory syndrome coronavirus 2 virus. Patients admitted to the ICU suffer from microvascular thrombosis, which may contribute to mortality. Read more
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Novel Outcome Biomarkers Identified With Targeted Proteomic Analyses of Plasma From Critically Ill Coronavirus Disease 2019 Patients
Critical Care Explorations
Objectives: Coronavirus disease 2019 patients admitted to the ICU have high mortality. The host response to coronavirus disease 2019 has only been partially elucidated, and prognostic biomarkers have not been identified. Read more
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Amino Acids in Circulatory Function and Health
Advances in Experimental Medicine and Biology
Cardiovascular disease is the major cause of global mortality and disability. Abundant evidence indicates that amino acids play a fundamental role in cardiovascular physiology and pathology. Decades of research established the importance of L-arginine in promoting vascular health through the generation of the gas nitric oxide. Read more
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Research!America's 2020 Health Research Forum available for viewing
Research! America, a collective advocating strong funding and policies that support the advancement of medical, health and scientific research, held its 2020 Virtual National Health Research Forum, "Straight Talk: Securing a Science-Strong Future," on September 8-11. As it has for over two decades, the National Health Research Forum gathered top federal officials, leadership from Research!America partners, and prominent media professionals to take a sober look at issues crucial to the wellbeing of our communities and all beneficiaries of life science research. Guest speakers scheduled for this year's event included NIH Director Francis Collins, FDA Commissioner Stephen Hahn, CDC Director Robert Redfield, and NIAID Director Anthony Fauci. Interactive panel discussions on vaccine hesitancy and health disparities were featured, as were "flash talks" featuring young scientists from academia and industry and powerful personal stories from patient advocates. The sessions will be available for viewing online until October 8.
Manuscripts sought on SARS CoV2 pathophysiology
American Journal of Physiology-Lung Cellular and Molecular Physiology has issued a call for papers on topics related to "The Pathophysiology of COVID-19 and SARS-CoV-2 Infection." Manuscripts are encouraged on development of suitable in vitro, ex vivo, and animal models of SARS CoV2 and other coronavirus infections. Additional topics of interest include identification of biomarkers to monitor physiological processes affected by SARS CoV2 infection, the pathophysiology relevant to viral replication in clinical disease or experimental models, and others. Question related to this call may be directed to AJP-Lung Editor-in-Chief Rory E. Morty or Physiological Reports Editor-in-Chief Dr. Thomas R. Kleyman. Deadline for submission is December 31, 2020.
Lingering cardiovascular consequences of COVID-19
Boston VA and Harvard Med Cardiologist Haider Warraich writes in the Aug 17, 2020, issue of the NY Times that myocarditis is emerging as a serious and frequent follow-on to SARS CoV2 infection, even in asymptomatic young patients without the common risk factors associated with severe pulmonary disease manifestations of COVID-19. Citing a recent German study published in JAMA Cardiology, Dr. Warraich comments on the alarming finding that nearly 80% of the 100 study participants had persistent abnormalities detected by MRI and 60% had evidence of myocarditis. Still unclear is how SARS-CoV-2 causes myocarditis: by causing injury directly or as a consequence of an aggressive host immune reaction.
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Frontiers in Cardiovascular Medicine
 Special Research Topics
Putting Engineering Back In Vascular Tissue Engineering To Advance Basic Science and Clinical Applications
Topic Editors: Jessica Wagenseil (Washington University in St. Louis) and W. Lee Murfee (University of Florida).
This topic is sponsored by NAVBO
Vascular tissue engineering (VTE) can be characterized as the creation of replacement vessels. Over the past 30 years, approaches have incorporated different combinations of extracellular matrix scaffolds, cells and biological active chemical cues. Challenged by the goal to recapitulate the complexity of big or small vessels, the clinical use of in vitro tissue engineered vessel replacements is still limited. With research more often focusing on reductionist materials science or cell biology characterization of vessel-like constructs, an opportunity has emerged to re-apply engineering approaches to guide the next step in VTE.
Submit your manuscript by October 17, 2020
What do we know about COVID-19 implications for cardiovascular disease?
The coronavirus epidemic causes major cardiovascular complications. Underlying mechanisms, however, remain incompletely understood. Frontiers in Cardiovascular Medicine invite you to submit your article on this topic. We consider all types of manuscripts: fundamental basic science reports, translational or clinical studies, review articles and methodology papers.
We have already published 17 articles. More submissions are currently under review. Due to the popularity and the emerging nature of this topic, we decided to extend the deadline to December 31, 2020. All articles submitted before this deadline will be published free of charge. We encourage you to take advantage of this opportunity to publish your original study or review article in FCVM (Impact Factor 3.915).
Comorbidities and aortic valve stenosis - molecular mechanism, risk factors and novel therapeutic options
Topic Editors: Claudia Goettsch, Felix Jansen and Cynthia St. Hilaire Aortic valve stenosis (AS) is the most prevalent valvular heart disease of the elderly population in the developed world, and the disease burden is estimated to increase from 2.5 million in 2000 to 4.5 million in 2030. Comorbidities like hypertension, type 2 diabetes mellitus, dyslipidemia, chronic kidney disease, COPD, chronic inflammatory diseases, and anemia are highly prevalent in this population. They not only influence the clinical course of AS and its prognosis, but affect therapeutic success. Submit your abstract by September 15, 2020 For more information, click here |
Dear friends and colleagues,
Jun Zhang, PhD (Associate Professor, Texas Tech University Health Sciences Center El Paso), is organizing a special issue entitled "Advancements in Cerebral Cavernous Malformations" in journal Vessel Plus (VP, ISSN 2574-1209).
This special issue aims to bring readers the up-to-date view of advancements in the scientific and technology innovations, translational and basic-science studies, and clinical trials of cerebral cavernous malformations. For more details about this special issue and the "Author Instructions", please visit the website at https://vpjournal.net/journal/special_detail/459.
Are you interested in contributing an article before February 15, 2021? If yes, please contact Jun Zhang (jun.zhang2000@gmail.com), the Guest Editor for this special issue, or Mavis Wei (mavis@vpjournal.net), the Managing Editor of VP. If you need additional information, please feel free to contact us.
VP is an online open access journal which was launched on March 31, 2017 by OAE Publishing Inc. It waives the Article Processing Charge (APC) for all publications since launched. Thus, your manuscripts will be published totally free of charge once officially accepted after quick and rigorous peer-review. Meanwhile, all manuscripts published in VP will be immediately available online for free downloading and reading. Further, if the work is funded by NIH, we can deposit it in PubMed on your behalf.
Thank you for considering this invitation.
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Dear friends and colleagues,
This special issue aims to provide readers with an up-to-date advancement in lesser-known genes, proteins and signaling pathways in vascular biology. Manuscripts related to concepts from these genes and proteins and their associated signaling pathways that connect into the well-established vascular ligand-receptor signaling systems are welcome. For more details about this special issue and the "Author Instructions", please visit the website at https://vpjournal.net/journal/special_detail/478. Are you interested in contributing an article before December 31, 2020? If yes, please contact Ramani Ramchandran (rramchan@mcw.edu), the Guest Editor for this special issue, or Mavis Wei (mavis@vpjournal.net), the Managing Editor of VP. If you need additional information, please feel free to contact us. VP is an online open access journal which was launched on March 31, 2017 by OAE Publishing Inc. It waives the Article Processing Charge (APC) for all publications since launched. Thus, your manuscripts will be published totally free of charge once officially accepted after quick and rigorous peer-review. Meanwhile, all manuscripts published in VP will be immediately available online for free downloading and reading. Further, if the work is funded by NIH, we can deposit it in PubMed on your behalf. Thank you for considering this invitation.
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