November 15, 2018
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Vascular Biology 
Monterey, CA  
October 27-31, 2019

Lymphatic Forum 2019
Austin, TX
May 31 - June 1, 2019

Vasculata 2019
Medical College of Wisconsin
July 13 - 18, 2019

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Include NAVBO in Your Holiday Plans
Consider supporting NAVBO this year.  Here are three great ways to do it!

1) If you shop at Amazon - please use this link: You shop and .5% of your purchase will go to support NAVBO!  
2) Buy a NAVBO branded item - shirts, hoodies or mugs and help support  our educational initiatives. Go to, purchase a few and give them as holiday gifts to everyone in your lab!

3) Make a year-end tax deductible contribution - November 27, is Giving Tuesday.  NAVBO is a designated as a 501(c)3 charity by the IRS and therefore, your contribution to NAVBO is tax deductible.  Please donate here:  You can stipulate how you want your donation used.

Thank you!
Call for Postdocs and Graduate Students
We are seeking volunteers for our Membership Committee. 
NAVBO strives to serve its members, especially those at the training level.  How better to serve than to include the insights, perceptions and needs of these junior investigators.   
If you would like to get more involved in NAVBO by participating in the Membership Committee, please contact Dr. Luke Brewster, Membership Committee Chair at and include your CV.
The Membership Committee seeks ways to engage and support members throughout their career.  If networking with a broader scope of colleagues interests you, please reach out to Dr. Brewster by November 15.
Current committee members will review the applications and select candidates by December 14.
Celebrating 25 Years!
Call for Volunteers!
NAVBO was incorporated in December 1994 and we are about to celebrate our 25th Anniversary!!
Everything is still in the planning stages.  If you would like to join the 25th Anniversary Committee, led by Drs. Cleaver and Galis, and help us initiate ways to celebrate and recognize our members, contact
We'd love to hear your ideas! 
Lessons Learned
Dr. John C. Chappell
The following is a portion of Dr. Chappell's reflections on his early career experiences. You will find the full version on the NAVBO website.
Maintain a work-life balance- Many careers can consume you, and a career in academic science can certainly tip the work-life balance towards working almost continuously. What started out as a passion and a curiosity to discover new things about the vascular system can quickly turn into seemingly endless grant writing, manuscript preparation, e-mail replies, and so on. I would urge new independent investigators to work hard on their science, but to also find the aspects of life that provide rest and reinvigoration outside of their science and the workplace. Striving for and maintaining that work-life balance seems to be a critical skill to help avoid burnout and sustain you through the highs and lows of grant/paper reviews and all of the other challenges you will face.
Find your place of Zen- In reading the Lessons Learned contributions from my colleagues, one theme emerges very clearly-this career path is full of many difficult challenges. Publishing, funding, managing a lab, etc. In the midst of the ups and downs, I have found that staying connected to the science and keeping my hands on the experiments has been incredibly helpful. My place of Zen is at my confocal, taking high-resolution images of biological phenomena - it has been my shelter during the storms of never-ending demands. Find the part of science that fueled your love of what you do, and fight to keep that as part of your schedule. I try to use my confocal at least once every week or two. It helps clear my mind and reinvigorates me, while also inspiring new ideas and avenues for research. I encourage you to find that quiet place of enlightenment, free from worrying about what you cannot change.
Be focused but stay curious- When I started down the path of a career in academic science, one aspect I enjoyed the most was that curiosity was encouraged. As many of my colleagues have cautioned me, staying focused is important for building a critical mass of productivity in a particular area. But I would encourage a balance. Write down your curiosities. One day you may have the personnel and funding to pursue an idea you initially thought was a tangent, but it could develop into an unexpected discovery.
 Read more from Dr. Chappell on aiming for clarity, seeking out mentoring, and daring to be provocative.

Lab of the Month
The Lab of Dr. John C. Chappell

This month we are highlighting the lab of Dr. John C. Chappell, an Assistant Professor in the Department of Biomedical Sciences and the Virginia Tech Carilion Research Institute. Find out more about Dr. Chappell and his lab at 
Funding Opportunities from NHLBI
NHLBI Funding Opportunity - Deadline Approaching
The Vascular Biology and Hypertension Branch of NHLBI is seeking applications to the following funding opportunity:
RFA-HL-17-22: Maximizing the Scientific Value of the NHLBI Biorepository: Scientific Opportunities for exploratory Research (R21).

This funding opportunity is to support meritorious exploratory research relevant to the NHLBI mission using the biospecimen collections that are stored in the NHLBI Biorepository and that are available through BioLINCC.  

The due date for AIDS applications is January 7, 2019. Requests must be submitted to BioLINCC no later than December 17, 2018 in order to be eligible to receive a Letter of Availability by this due date.

For more information on RFA-HL-17-022 please visit:
To view available biospecimen collections and initiate a request, please visit:  
Spotlight on Trainees (from the November 1 issue)
Quality mentoring of PhD scientists crucial for success in career launch
Andrea M. Zimmerman from the Office of Continuing Medical Education at the University of Virginia has published "Navigating the path to a biomedical science career" in PLoS One (9/7/18), examining the multifactorial nature of PhD trainees' experiences in the biomedical sciences and how they approach their career choices.  It is well known that the number of newly-minted life science PhDs exceeds the number of opportunities in academe. Using social cognitive career theory and data gleaned from case studies, the author concludes that mentoring relationships with faculty are key to successful navigation of career paths in a challenging employment marketplace.
Member News
Welcome to our New Member:
Sumana Chintalapudi, Boston Children's Hospital

If you have news to share with your colleagues, send it to
 Recent Publications by NAVBO Members

Lysophosphatidic acid acts on LPA1 receptor to increase H2O2 during flow-induced dilation in human adipose arterioles
British Journal of Pharmacology
NO produces arteriolar flow-induced dilation (FID) in healthy subjects but is replaced by mitochondria-derived hydrogen peroxide (mtH2O2) in patients with coronary artery disease (CAD).  Read more


A current view of G protein-coupled receptor - mediated signaling in pulmonary hypertension: finding opportunities for therapeutic intervention
Vessel Plus
Pathological vascular remodeling is observed in various cardiovascular diseases including pulmonary hypertension (PH), a disease of unknown etiology that has been characterized by pulmonary artery vasoconstriction, right ventricular hypertrophy, vascular inflammation, and abnormal angiogenesis in pulmonary circulation.  Read more


Glutaminase-1 stimulates the proliferation, migration, and survival of human endothelial cells
Biochemical Pharmacology
Glutaminase-1 (GLS1) is a mitochondrial enzyme found in endothelial cells (ECs) that metabolizes glutamine to glutamate and ammonia.  Read more


Versican is differentially regulated in the adventitial and medial layers of human vein grafts
Changes in extracellular matrix proteins may contribute significantly to the adaptation of vein grafts to the arterial circulation.  Read more


A role for proteoglycans in vascular disease
Matrix Biology
The content of proteoglycans (PGs) is low in the extracellular matrix (ECM) of vascular tissue, but increases dramatically in all phases of vascular disease.  Read more


HIV-Nef Protein Persists in the Lungs of Aviremic HIV Patients and Induces Endothelial Cell Death
American Journal of Respiratory Cell and Molecular Biology
It remains a mystery why HIV-associated end-organ pathologies persist in the era of combined antiretroviral therapy (ART).  Read more

Industry News (from the November 1 issue)
"Million Hearts 2022" seeks to reduce mortality in cardiovascular disease  
The profound advances in prevention, diagnosis and treatment of heart and peripheral vascular diseases over the last half century resulted in a celebrated drop in rates of death owing to cardiovascular disorders. Now, this drop has abated and even changed course in adults aged 35 to 64, where deaths attributable to heart disease are on the increase. In view of this shift in medical fortunes, the US Centers for Disease Control and Prevention has launched Million Hearts 2022, emphasizing adoption of, and adherence to, those measures already proven to improve and sustain cardiovascular health. Janet Wright, MD, and her CDC colleagues note in JAMA that persistence of multiple behaviors and other factors stand in the way of progress, notably physical inactivity, smoking, uncontrolled high blood pressure, and hypercholesterolemia.

What makes science 'hard' in an era when the very value and nature of evidence is questioned?
French philosopher Bruno Latour created a stir in the late 20th century by positing that scientific facts were "social constructions," that is, created by scientific research rather than standing freely and objectively apart from the investigation that reveals said facts.  The "realists" who countered this view feared that constructionists would undermine scientific progress, legitimizing creationism and encouraging the anti-vaccine movement.  The debate produced memorable salvos, including an invitation from physicist Alan Sokal that Latour step out his 21st-floor window if the laws of physics were nothing more than social conventions.  In the New York Times Magazine, Ava Kofman explores the implications of Latour's legacy for the present post-fact era.

Cardiovascular aspects of endocrine disorders highlighted
The Endocrine Society has joined forces with the medical information system MedPage Today and the American College of Cardiology (ACC) to create an online resource that brings to the foreground leading research exploring important connections between cardiovascular and endocrine diseases.  Dubbed the Cardio-Endo Connection, the web presence aims to inform both primary care physicians and endocrine and CV specialists about important mutual concerns.  The site's inaugural offerings probe cardiovascular benefits of modified metformin therapy in Type 2 diabetes as well as management of primary aldosteronism.
Job Postings
Partner Network Advantage - New Job Board Feature
Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
Post your open position now at! 
Calendar of Events
April 11 - 13, 2019
11th Congress of the Vascular Access Society
May 30 - June 1, 2019
Lymphatic Forum 2019
July 6 - 10, 2019
International Society on Thrombosis and Hemostasis Congress 2019
Oct. 27 - 31, 2019
Vascular Biology 2019
Sept. 9 - 12, 2020
IVBM 2020
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