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William R. Huckle, Editor
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Join over 400 of your colleagues who have already registered!
Vascular Biology 2020
An exciting virtual event
October 26-29, 2020
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Boston, MA
Postponed until Summer 2021
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Vascular Biology Publications Alert Now Available by Subscription
The NAVBO Vascular Biology Publications Alert will now be available to non-members for a $55 a year subscription. If you would like to receive this alert, but are not a member, please contact Danielle at membership@navbo.org.
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Partner Network Advantage on the NAVBO Job Board
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Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
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Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes. Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25,2018. The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
Contact NAVBO if you have any questions or to change your communication preferences.
Please note, you can unsubscribe to this newsletter at anytime by clicking on the SafeUnsubscribe in the footer.
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Springer Junior Investigator Award
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Congratulations to Zhen Chen - Named the 2020 Springer Junior Investigator Award Recipient
The NAVBO Meritorious Awards Committee and NAVBO Council are pleased to announce that Zhen B. Chen, BMed, Ph.D. is the recipient of the 2020 Springer Junior Investigator Award, for which vascular biologists within five years of their first independent investigator position are eligible. Dr. Chen currently holds appointments as Assistant Professor, Department of Diabetes Complications and Metabolism, Beckman Research Institute, City of Hope and Assistant Professor, Irell and Manella Graduate School of Biological Sciences, City of Hope. Her work focuses on epigenetic regulation in endothelial stress response and its functional and translational relevance in cardiovascular diseases.
Please join us at Vascular Biology 2020 to hear Dr. Chen's Springer Award lecture, "Suppression of Endothelial AGO1 Promotes Adipose Tissue Browning and Improves Metabolic Dysfunction," at 10:15am ET on Thursday, October 29, 2020. Congratulations, Dr. Chen!
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Benditt and Folkman Award Lectures
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Earl P. Benditt Award Lecture
Patricia D'Amore, PhD, MBA, the 2020 recipient of the Earl P. Benditt Award for her numerous contributions to our understanding of vascular development and growth, will present the Benditt Award Lecture "Understanding capillary growth and pathology using the retina as a model system," via an online webinar on November 5 at 1:00pmET. Long-time associate, Michael Gimbrone, will deliver an introduction and chair the session.
The webinar will be accessible to all NAVBO members.
Judah Folkman in Vascular Biology Award
Kristy Red-Horse, PhD, recipient of the 2020 Judah Folkman Award in Vascular Biology will present the Folkman Award Lecture, titled "Artery Development and Regeneration," as an online webinar on November 2 at 1:00pm ET hosted by Sophie Astrof. The webinar will be accessible to all NAVBO members. The award recognizes her outstanding contributions in the following areas: molecular mechanisms and cellular lineages in coronary artery development and regeneration; single cell transcriptomics of the coronary vasculature; support of myocardial growth by the coronary endothelium; and transcriptional and mechanical regulation of coronary artery patterning
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There's More to Experience at Vascular Biology 2020!
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Don't Miss the Live Event!
Although speakers' presentations will be available for replay after the sessions (through November 28), the Q&A portion of the sessions will NOT be recorded. This will allow for the discussion of some new and exciting data so plan to attend sessions as they are broadcast.
In addition, we have added several exciting Round Tables.* The formats are dictated by the moderators. Topics were inspired by registrants' suggestions, meeting organizers and NAVBO Committees.
- Applying Lessons Learned from Vascular Development
- Blood Brain Barrier in Health and Disease
- COVID-19: The Vasculature Unleashed
- Lymphatics and Lymphoid Tissue in Tumor Progression and Metastasis
- Resolution of Inflammation
- Single Cell RNA-sequencing
- Transendothelial Migration
- Academic Path for Women and Minorities: Imposter Syndrome
- Calls for Social Justice: We Need to Act
- Career Developments for Trainees and Early Stage Investigators from Underrepresented Communities and Beyond
- Challenges of Internationally Trained Scholars: Let's share tips on how to succeed in the U.S.
- Grant Writing Round Table: Reviews, Revisions, and Resubmissions
- How to build an Academic-Industry Partnership Research Hub
- Training Challenges in the COVID-19 Era
We will have Poster Discussions* in the following topics:
- Atherosclersosis/Restenosis
- Emerging Topics in Microcirculation
Sponsored by the Microcirculatory Society - Inflammation in Special Vascular Beds
Sponsored by the American Society for Investigative Pathology - Lympthatics
- Neurovascular Inflammation Poster Discussion
- Signaling in Development
- Signaling in Inflammation and Transmigration
- Vascular Malformations
*Poster Discussions and Round Tables that are scientific in nature will NOT be recorded. Those related to career development and training will be recorded and available through 11/28.
These sessions will be limited to 30 attendees in order to promote in-depth conversations. You can preregister for sessions within the meeting platform once you log in on October 12.
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We are very excited to be joined by: The Microcirculatory Society and the
American Society for Investigative Pathology
The preliminary program/schedule is available at
Poster Discussions and Round Tables have been added
Tweet this! Register for Vascular Biology 2020 |
The Lab of Dr. Ramani Ramchandran
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Thrombosis and Haemostasis
Thrombosis and Haemostasis provides a forum for the exchange of ideas and concepts fostering cross-disciplinary insights in basic and clinical research. The journal is published monthly in print and online via Thieme E-Journals.
It is covered in the main abstracting and indexing services and has an impact factor of 4.379.
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Funding opportunity to support undergraduate research
As we are all aware, equal opportunities cannot and should not be taken for granted. NAVBO has initiated a funding platform to support diversity and inclusion efforts at the undergraduate and graduate student career stages.
NAVBO has obtained funding via an NIH-funded grant to the Medical College of Wisconsin to support the educational training of students. This training includes the attendance at a scientific conference or webinar. NAVBO trainee members can participate in several webinars throughout the year, thus recruiting new members will bring more educational opportunities to these trainees.
We would like to use this grant to help increase diversity and inclusion within the vascular biology community, expose more young scientists to the field of vascular biology, and to bring more trainees into this collaborative community. Therefore, we are extending this offer of free membership to students who are members of populations that are not well represented in vascular biology, including but not limited to Black/African American, Latinx/Hispanic, Indigenous Peoples of America/Native American (including Native Hawaiian and Alaskan), and LGBTQ+. NAVBO is also extending this offer to students who may be at a financial disadvantage and would benefit from this opportunity.
In order to take advantage of this offer, students should send their CV to membership@navbo.org. If not included in their CV, all contact information should be included in the email. A supervisor must send an email to membership@navbo.org confirming the candidates' status as a student and as being a member of one of the populations listed above.
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Angiogenesis pioneer Robert Auerbach honored on his 90th birthday
 A special September 2020 issue of Anatomia, Histologia, Embryologia, organized by Johanna Plendl of the Institute of Veterinary Anatomy at the Freie Universtaet Berlin, has been published in honor of Robert Auerbach's many contributions to vascular biology and in celebration of his 90th birthday. Dr. Auerbach, working with Judah Folkman, made early observations about the pro-angiogenic properties of transplanted tumors, providing key elements of rationale for pursuit of anti-angiogenic cancer therapies. The special issue, which features an editorial tribute to Dr. Auerbach by Dr. Plendl and will be available free on line for at least six months, presents the findings of scientists working in the fields of veterinary anatomy, histology and embryology on "Angiogenesis: Cells, Tissues and Organs." Congratulations Dr. Auerbach...and Happy Birthday!
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Harvard Medical School Seminars in Vascular Biology
Organized by several NAVBO members (Peter Libby, Michael Gimbrone, Masanori Aikawa, Guillermo Garcia-Cardena, and Patricia D'Amore), this seminar series offers weekly talks on Thursdays at 4:30 PM (ET). Here's what's coming up this month:
October 8
Jonathan Kipnis, PhD
Washington University in St. Louis, School of Medicine
"Meningeal Blood and Lymphatic Vasculature in Brain's Maintenance"
October 15
Melody Swartz, PhD
University of Chicago
"Lymphatic Endothelium in Inflammation and Immunity"
October 22
Peter Libby, MD
Brigham and Women's Hospital,Harvard Medical School
"COVID-19 and the Cardiovascular System"
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Welcome to our New Members:
Ahmed Abdel-Latif, University of Kentucky
Cyrus Abrahamson, Northwestern University
Mikaela Aquino, University of Illinois - Chicago
Kevin Brulois, Stanford University
Thaddaeus Castañeda II, The University of Toledo
Manish Dasyani, Cincinnati Children's Hospital Medical Center
Jonnelle Edwards, The University of Toledo
Kayleigh Fanelli, Ohio University
Lionel Gillot, ULiège
Max Grönloh, Sanquin Research and Landsteiner Laboratory
Tomasz Kaminski, University of Pittsburgh
Shunsuke Katsuki, Kyushu University
Annie Ryan, UT Southwestern Medical Center
Emily Waigi, The University of Toledo
Micaela Young, Medical College of Wisconsin
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| Recent Publications by NAVBO Members |
Fibrotic Changes and Endothelial-to-Mesenchymal Transition Promoted by VEGFR2 Antagonism Alter the Therapeutic Effects of VEGFA Pathway Blockage in a Mouse Model of Choroidal Neovascularization
Cells
Many patients with wet age-related macular degeneration do not respond well to anti- vascular endothelial growth factor A (VEGFA) therapy for choroidal neovascularization (CNV), and the efficacy of anti-VEGFA decreases over time. We investigated the hypothesis that fibrotic changes, in particular via endothelial-to-mesenchymal transition (EndoMT), play a role in CNV and alter the therapeutic effects of VEGFA pathway blockage. Read more
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Heterogeneity and chimerism of endothelial cells revealed by single-cell transcriptome in orthotopic liver tumors
Angiogenesis
The liver is a common host organ for cancer, either through lesions that arise in liver epithelial cells [e.g., hepatocellular carcinoma (HCC)] or as a site of metastasis by tumors arising in other organs (e.g., colorectal cancer). Read more
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Pleiotrophin selectively binds to vascular endothelial growth factor receptor 2 and inhibits or stimulates cell migration depending on ανβ3 integrin expression
Angiogenesis
Pleiotrophin (PTN) has a moderate stimulatory effect on endothelial cell migration through ανβ3 integrin, while it decreases the stimulatory effect of vascular endothelial growth factor A (VEGFA) and inhibits cell migration in the absence of ανβ3 through unknown mechanism(s). Read more
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Novel Murine Models of Cerebral Cavernous Malformations
Angiogenesis
Cerebral cavernous malformations (CCMs) are ectatic capillary-venous malformations that develop in approximately 0.5% of the population. Patients with CCMs may develop headaches, focal neurologic deficits, seizures, and hemorrhages. Read more
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Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
Angiogenesis
Platelet-derived growth factor-B (PDGF-B) is a main factor to promote adipose tissue angiogenesis, which is responsible for the tissue expansion in obesity. In this process, PDGF-B induces the dissociation of pericytes from blood vessels; however, its regulatory mechanism remains unclear. Read more
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Courses in clinical lipidology available
The International Atherosclerosis Society (IAS) is collaborating with the National Lipid Association (NLA) to offer the Foundations in Lipidology Course and the Masters in Lipidology Training Course. Foundations of Lipidology provides an introduction to clinical lipidology for healthcare professional seeking to gain the knowledge and tools necessary to work effectively in a lipid practice. Masters in Lipidology is an intensive 14.75 hour course offering an in-depth core curriculum in Clinical Lipidology for health care professionals who desire to practice at an advanced level. For further information or to register, visit the IAS website; discounted registration is available to NLA members.
COVID-19 Evidence Hub herds the cats of coronavirus research findings
Earlier this year, the consumer advocacy group Center for Science in the Public Interest (CSPI) launched a COVID-19 Evidence Hub. This initiative was created to systematize the mounting array of global COVID-19 scientific research findings and respond to the resulting challenge for researchers, clinicians, journalists, and decisions makers to efficiently digest a large volume of new, rapidly evolving evidence. The Hub is a web directory of publicly available websites dedicated to COVID-19 research. Each included website includes a database of new/ongoing studies, a database of study results, appraisals of the emerging evidence, or a combination of the three. The CSPI encourages us to share this resource widely within our respective networks of colleagues and organizations.
Imitation is the sincerest form of...cardioprotection?
Verve Therapeutics, founded in 2018 by Sekar Kathiresan and fellow cardiovascular genetics researchers and operating with gene editing technologies licensed from Beam Therapeutics, Harvard University, and the Broad Institute, is developing protocols to edit the adult human genome to leave gene variants that mimic naturally occurring cardioprotective variants. Kathiresan and colleagues have identified variants in eight genes associated with low cholesterol in individuals throughout life who, as quoted in the August 2020 Genetic Engineering and Biotechnology News, are "remarkably protected against heart attack." Targeting PCSK9 in nonhuman primates showed a 59% reduction in blood LDL cholesterol. Blood triglycerides were lowered by 64% and LDL cholesterol was reduced 19% in other studies targeting ANGPTL3.
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Frontiers in Cardiovascular Medicine
 Special Research Topics
Putting Engineering Back In Vascular Tissue Engineering To Advance Basic Science and Clinical Applications
Topic Editors: Jessica Wagenseil (Washington University in St. Louis) and W. Lee Murfee (University of Florida).
This topic is sponsored by NAVBO
Vascular tissue engineering (VTE) can be characterized as the creation of replacement vessels. Over the past 30 years, approaches have incorporated different combinations of extracellular matrix scaffolds, cells and biological active chemical cues. Challenged by the goal to recapitulate the complexity of big or small vessels, the clinical use of in vitro tissue engineered vessel replacements is still limited. With research more often focusing on reductionist materials science or cell biology characterization of vessel-like constructs, an opportunity has emerged to re-apply engineering approaches to guide the next step in VTE.
Submit your manuscript by October 17, 2020
What do we know about COVID-19 implications for cardiovascular disease?
The coronavirus epidemic causes major cardiovascular complications. Underlying mechanisms, however, remain incompletely understood. Frontiers in Cardiovascular Medicine invite you to submit your article on this topic. We consider all types of manuscripts: fundamental basic science reports, translational or clinical studies, review articles and methodology papers.
We have already published 17 articles. More submissions are currently under review. Due to the popularity and the emerging nature of this topic, we decided to extend the deadline to December 31, 2020. All articles submitted before this deadline will be published free of charge. We encourage you to take advantage of this opportunity to publish your original study or review article in FCVM (Impact Factor 3.915).
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Dear friends and colleagues,
Jun Zhang, PhD (Associate Professor, Texas Tech University Health Sciences Center El Paso), is organizing a special issue entitled "Advancements in Cerebral Cavernous Malformations" in journal Vessel Plus (VP, ISSN 2574-1209).
This special issue aims to bring readers the up-to-date view of advancements in the scientific and technology innovations, translational and basic-science studies, and clinical trials of cerebral cavernous malformations. For more details about this special issue and the "Author Instructions", please visit the website at https://vpjournal.net/journal/special_detail/459.
Are you interested in contributing an article before February 15, 2021? If yes, please contact Jun Zhang (jun.zhang2000@gmail.com), the Guest Editor for this special issue, or Mavis Wei (mavis@vpjournal.net), the Managing Editor of VP. If you need additional information, please feel free to contact us.
VP is an online open access journal which was launched on March 31, 2017 by OAE Publishing Inc. It waives the Article Processing Charge (APC) for all publications since launched. Thus, your manuscripts will be published totally free of charge once officially accepted after quick and rigorous peer-review. Meanwhile, all manuscripts published in VP will be immediately available online for free downloading and reading. Further, if the work is funded by NIH, we can deposit it in PubMed on your behalf.
Thank you for considering this invitation.
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Dear friends and colleagues,
This special issue aims to provide readers with an up-to-date advancement in lesser-known genes, proteins and signaling pathways in vascular biology. Manuscripts related to concepts from these genes and proteins and their associated signaling pathways that connect into the well-established vascular ligand-receptor signaling systems are welcome. For more details about this special issue and the "Author Instructions", please visit the website at https://vpjournal.net/journal/special_detail/478. Are you interested in contributing an article before December 31, 2020? If yes, please contact Ramani Ramchandran (rramchan@mcw.edu), the Guest Editor for this special issue, or Mavis Wei (mavis@vpjournal.net), the Managing Editor of VP. If you need additional information, please feel free to contact us. VP is an online open access journal which was launched on March 31, 2017 by OAE Publishing Inc. It waives the Article Processing Charge (APC) for all publications since launched. Thus, your manuscripts will be published totally free of charge once officially accepted after quick and rigorous peer-review. Meanwhile, all manuscripts published in VP will be immediately available online for free downloading and reading. Further, if the work is funded by NIH, we can deposit it in PubMed on your behalf. Thank you for considering this invitation.
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