June 27, 2019
Home           Membership           Events           Awards           Resources
In This Issue
Join      Rejoin     Renew
Vascular Biology 
Monterey, CA  

Vasculata 2019
Medical College of Wisconsin
July 13 - 18, 2019

Corporate Partners
Corporate Members

VB2019 Guest Society
VB2019 Supporters

VB2019 Exhibitors


Affiliated Journals
Partner Network Advantage - New Job Board Feature
Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
Post your open position now at www.navbo.org/jobs! 
Shop at Amazon?   
Help Support NAVBO 
NAVBO Privacy Policy
Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes. Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25.   The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
Contact NAVBO if you have any questions or to change your communication preferences.
 Please note, you can unsubscribe to this newsletter at anytime by clicking on the SafeUnsubscribe in the footer.
*Product News is a paid advertising space. For more information go to: http://www.navbo.org/images/MediaKit-NewsBEAT.pdf
Live Stream Vasculata 2019 to Your Institution
Vasculata 2019 - July 15-18 
Medical College of Wisconsin
If you can't make it to Milwaukee, bring Vasculata to your institution!

Live stream Vasculata to your institution and interact with the speakers in the Q&A sessions and have access to the mobile app, which will contain supporting materials for lectures.  You might even have your own poster session.

Your group will have access to the keynote talks by Luisa Iruela-Arispe and
Curt D. Sigmund as well as all the lectures from Monday, July 15 through Thursday, July 18.  See http://www.navbo.org/events/vasculata2019/webcast2019 for all the details and how you can register.

Go to http://www.navbo.org/vasculata for more meeting information.

Please note - we are still able to accept abstracts for poster presentation on a space available basis. Registration is still open.
Election Results for NAVBO Council
Masanori Aikawa is our next President-Elect
In addition to Dr. Aikawa (Brigham & Women's Hospital, Harvard Medical School) being elected to the Presidential  track, Linda Shapiro of the University of Connecticut and Cynthia St. Hilaire of the Pittsburgh Heart, Lung and Vascular Biology Institute have been elected as Councilors.  

Special thanks to Drs. Guillermo Oliver (Northwestern University), Christopher Carman (Harvard T. H. Chan School of Public Health), Hyung Chun (Yale School of Medicine), Tsutomu Kume (Northwestern University) and Radu Stan (Geisel School of Medicine at Dartmouth) for their willingness to run for office and their dedication and support of NAVBO.
NEW!!!  VB2019 Grants for Child Care
NAVBO announces grants to support child care expenses
The NAVBO Council voted to support grants for family members who may need additional support when attending a meeting.  Go to http://www.navbo.org/events/vb2019/childcare19/childcareinfo for more information and to apply.

Help support these grants by purchasing a Vascular Biology networking T-shirt or by giving a donation.  NAVBO will support five grants at $400 each;  all funds raised in this manner, even if above $2,000, will support these grants.  Thank you for your support.
Buy a T-shirt (or mug)
Make a donation (Select quantity 1 for $25; quantity 2 for $50, etc.)
Promote Your Presentation on the Web Site
Current NAVBO Members Can List Their Upcoming Presentations (Oral or Poster) on our Web Site
Keep members, and all who visit our web site, aware of presentations by NAVBO members.  If you are attending the meeting, be sure to attend your NAVBO colleague's presentation.  If you are also presenting at that meeting, you can attend each other's presentations and offer mutual support! It can also help make you aware when a colleague is in your town so you reach out and arrange an in-person chat. And finally, this listing can also keep you abreast of other relevant meetings and  conferences.

So check out the current listings: http://www.navbo.org/membership/meeting-presentations-by-members and add yours!
There is a form at the bottom of the page for you to add your presentation.
Next Webinar to Feature Vicki Bautch
How Blood Vessels Control Their Own Destiny
Please join  us on July 11 at 1:00pm EDT for a webinar featuring Dr. Vicki Bautch of North Carolina University at Chapel Hill.   
Here is an overview of her presentation: Blood vessel formation requires the precise spatial and temporal regulation of interactions between gradient-forming, pro-angiogenic signals (e.g., VEGF-A and BMP) and endothelial cells in developing organs. These pro-angiogenic pathways may be modulated by negative regulators that originate in target endothelial cells, including the VEGF-A decoy soluble Flt1/VEGFR1 and SMAD6, which binds BMP receptors and blunts BMP signaling. Genetic deletion of either Flt1 or SMAD6 is associated with defective vessel architecture and integrity and is lethal during embryonic or early post-natal stages, highlighting the importance of negative regulators of VEGF-A and BMP signaling for normal vessel formation and stabilization.
For more details and to register go to: http://www.navbo.org/events/webinars/816-web072019
NAVBO Webinars are free to current NAVBO Members.

Upcoming Webinars:
August 1 - Masanori Aikawa, Brigham & Women's Hospital 
September - Carlos Fernández-Hernando, Yale School of Medicine 
October - Sathish Srinivasan, Oklahoma Medical Research Foundation  
And don't forget you can watch archived webinars as well - go to  
Spotlight on Trainees (from June 13, 2019 issue)
What sets you apart...in a good way?
"No one deserves to go through life not being able to see their worth."  So avers #UniqueScientists, a website devoted to celebrating diversity in science.  The team behind #UniqueScientists seeks to encourage diversity in the scientific realm by sharing the personal stories of contributing scientists from around the world.  The site encourages readers and contributors alike to question the notion that self-identity should be a determining factor in one's chosen career.  NAVBO trainees who meet the dual criteria for submitters (Are you a human? and Are you a scientist...?) are invited to consider submitting their story for inclusion on the site.  Get out there and represent vascular biology!
Call for Papers - Single-Cell Anaylysis
A Frontiers Research Topic initiated by NAVBO
Recent advances in analyzing tissues and organs at the single cell (SC) level are revolutionizing our understanding of organ development, biology, and disease. Previously, the genetic composition or transcriptional profiles of cells was based on sequencing DNA or RNA from a large number of cells, but this approach loses information on the heterogeneity of individual cells. Sequencing DNA and RNA from individual cells preserves heterogeneity, and technological advances have made these techniques highly accessible.

A recent analysis - available here - of the SC extramural research funded by the NIH, either through NIH-initiated programs focused on SC or initiated by extramural investigators, revealed the paucity of such analyses related to vascular cells compared to a variety of other cells and tissues. This Research Topic is seeking to galvanize interest in SC applications related to the field of vascular cell biology and highlight original research related to SC analyses of vascular related cells, under normal or diseased conditions. We seek to understand the specific challenges associated with studying vascular cells, and how advances in SC approaches could benefit vascular fields. Submissions are due September 30, 2019. More information can be found here on the Frontiers web site.
Product News*
Introducing ACS Pharmacology & Translational Science

ACS Pharmacology & Translational Science
 is a new journal from the American Chemical Society publishing high-quality, innovative research across the broad spectrum of biological sciences.
Read Volume 2, Issue 1, free courtesy of ACS Publications.  
And don't miss NAVBO member Professor Kathleen M. Caron's latest work in our Articles ASAP.
NAVBO YouTube Channel
Feedback Welcomed!
Have you visited the NAVBO YouTube Channel?  Click Here
The included playlists were compiled by members of the Education Committee led by Drs. Michael Dellinger and Luis Hortells.  We would love to hear feedback from our members.  We encourage trainees to view them (each video was reviewed for accuracy by members of the committee).
Please feel free to recommend a video that you have seen on YouTube; we'll review it and perhaps add it to our channel.
Send your comments and any recommendations to Anita Pustelnik ( anita@navbo.org ). 
Member News
Welcome to our New Members:
Erika Hooker, Université de Montréal
David Hootnick, David R. Hootnick, MD, PLLC
Bruno Larrivée, Université de Montréal
Masahide Sakabe, Cincinnati Children's Hospital
Kiran Sriram, City of Hope
Claire Viallard, Université de Montréal

If you have news to share with your colleagues, send it to membership@navbo.org
 Recent Publications by NAVBO Members

Partial Deletion of Tie2 Affects Microvascular Endothelial Responses to Critical Illness in A Vascular Bed and Organ-Specific Way
Tyrosine kinase receptor (Tie2) is mainly expressed by endothelial cells. In animal models mimicking critical illness, Tie2 levels in organs are temporarily reduced. Functional consequences of these reduced Tie2 levels on microvascular endothelial behavior are unknown.  Read more


Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction
European Heart Journal
AIMS: A better understanding of the pathways that regulate regeneration of the coronary vasculature is of fundamental importance for the advancement of strategies to treat patients with heart disease.  Read more


Building Blood Vessels - One Rho GTPase at a Time
Blood vessels are required for the survival of any organism larger than the oxygen diffusion limit. Blood vessel formation is a tightly regulated event and vessel growth or changes in permeability are linked to a number of diseases.  Read more


Medial artery calcification increases neointimal hyperplasia after balloon injury
Scientific Reports
Arterial calcification predicts accelerated restenosis after angioplasty and stenting. We studied the effects of calcification on neointimal hyperplasia after balloon injury in the rat carotid.  Read more


Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms
Journal of Clinical Investigation Insight
Marfan syndrome (MFS) is associated with mutations in fibrillin-1 that predispose afflicted individuals to progressive thoracic aortic aneurysm (TAA) leading to dissection and rupture of the vessel wall.  Read more


KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D
Vascular endothelial growth factor-C (VEGF-C) acts primarily on endothelial cells, but also on non-vascular targets, e.g. in the CNS and immune system.  Read more


Powerful Homeostatic Control of Oligodendroglial Lineage by PDGFRa in Adult Brain
Cell Reports
Oligodendrocyte progenitor cells (OPCs) are widely distributed cells of ramified morphology in adult brain that express PDGFRa and NG2.  Read more


Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies
Nature Communications
The high selectivity of the human blood-brain barrier (BBB) restricts delivery of many pharmaceuticals and therapeutic antibodies to the central nervous system.  Read more


Consensus guidelines for the use and interpretation of angiogenesis assays
The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions.  Read more

Industry News (from June 13, 2019 issue)
Federal legislative updates from Research!America
News from the desk of Mary Woolley, President and CEO of Research!America, includes concerns about the future of fetal tissue research in the US, reminders about the impact of the 1980 Bayh-Dole Act on technology transfer, and exhortations for us scientists to advocate for robust federal funding of research as the FY20 budgeting process rolls out. Research!America and its partners in advocacy plan to meet on June 26, 2019, for a Capitol Hill briefing, examining advances in research aimed to improve delivery of care to patients living in rural areas. Details and registration info may be found here .
Registration opens for 2019 AAMC Annual Meeting in Phoenix
The American Association of Medical Colleges has released programming and registration details for its 2019 meeting, scheduled for November 8-12 in Phoenix. The AAMC meeting aims to tackle significant issues in medical education, patient care, and biomedical research. Keynote speakers includeBryan Stevenson, JD, founder and executive director of the Equal Justice Initiative and author of Just Mercy; Jon Meacham Presidential historian and Pulitzer Prize-winning author of American Lion: Andrew Jackson in the White House and The Soul of America: The Battle for Our Better Angels; and Amy Edmondson, PhD, Author and Novartis Professor of Leadership and Management, Harvard Business School.

Remarkable therapy; astonishing expense
Bloomberg Opinion's Max Nisen, writing in   The Washington Post, examines the ramifications of the multimillion dollar price tag attached to Zolgensma, Novartis AG's one-time gene therapy treatment for spinal muscular atrophy that was approved by the FDA in May. While Zolgensma offers the prospect of curing a disease that is typically fatal before age two, critics fear that the monumental price will become an accepted reference point for new gene therapies in the pipeline. "Miracle cures don't do much good, "notes Nisen, "if they aren't accessible." 
Job Postings
Calendar of Events
July 1 - 2, 2019
31st UK Cell Adhesion Meeting
July 6 - 10, 2019
International Society on Thrombosis and Hemostasis Congress 2019
July 10 - 12 2019
ASMB/Vanderbilt 2019 Workshop on Basement Membranes
July 21 - 26, 2019
GRC - Elastin, Elastic Fibers, and Microfibrils
August 4 - 9, 2019
2019 Angiogenesis Gordon Conference
Oct 27 - 31, 2019
Vascular Biology 2019
North American Vascular Biology Organization | bernadette@navbo.org | http://www.navbo.org
18501 Kingshill Road
Germantown, MD 20874-2211