November 1, 2018
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Vascular Biology 
Newport, RI 

Lymphatic Forum 2019
Austin, TX
May 31 - June 1, 2019

Vasculata 2019
Medical College of Wisconsin
July 13 - 18, 2019

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VB2018 Exhibitors

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Shop at Amazon?   
Help Support NAVBO 
Use this link to shop for everyone and everything and Amazon will donate to NAVBO.
Today and tomorrow only - Amazon will donate 5% of your purchase to NAVBO.  This is 10x the normal rate! 
Partner Network Advantage - New Job Board Feature
Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
Post your open position now at! 
NAVBO Privacy Policy
Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes. Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25.   The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
Contact NAVBO if you have any questions or to change your communication preferences.
 Please note, you can unsubscribe to this newsletter at anytime by clicking on the SafeUnsubscribe in the footer.
Upcoming Webinar with Anne Eichmann
Lacteal Junction Zippering Protects Against Diet-induced Obesity
Join us on November 8, 1:00pm EST as Dr. Anne Eichmann, Ph.D., a Professor in the Departments of Medicine (Cardiology) and Cellular and Molecular Physiology at the Yale Cardiovascular Research Center.  This webinar is free to all NAVBO members.  Non-members pay $25 per webinar.
Call for Postdocs and Graduate Students
We are seeking volunteers for our Membership Committee. 
NAVBO strives to serve its members, especially those at the training level.  How better to serve than to include the insights, perceptions and needs of these junior investigators.  
If you would like to get more involved in NAVBO by participating in the Membership Committee, please contact Dr. Luke Brewster, Membership Committee Chair at and include your CV.
The Membership Committee seeks ways to engage and support members throughout their career.  If networking with a broader scope of colleagues interests you, please reach out to Dr. Brewster by November 15.
Current committee members will review the applications and select candidates by December 14.
Celebrating 25 Years!
Call for Volunteers!
NAVBO was incorporated in December 1994 and we are about to celebrate our 25th Anniversary!!
Everything is still in the planning stages.  If you would like to join the 25th Anniversary Committee, led by Drs. Cleaver and Galis, and help us initiate ways to celebrate and recognize our members, contact
We'd love to hear your ideas! 
Vascular Biology 2018 - Trainee Awards

Congratulations to our Travel Award Recipients:
Vascular Inflammation Workshop:
Mabruka Alfaidi, LSU Health Sciences Center - Shreveport
Thanh Theresa Dinh, Stanford University
Eric Engelbrecht, Boston Children's Hospital
Rajat Gupta, Brigham and Women's Hospital
Hideyuki Higashi, Brigham and Women's Hospital
Peter Kip, Brigham and Women's Hospital/Harvard Medical School*
Sarah-Anne Nicholas, University of Connecticut Health
Brian Sansbury, Harvard Medical School/Brigham and Women's Hospital
Shawn Veitch, University of Toronto*

Biology of Signaling in the Cardiovascular System Workshop:
Nicholas Chavkin, University of Virginia*
Julius Decano, Brigham and Women's Hospital
Melanie Hofmann, Hannover Medical School
Nadiya Khyzha, University Health Network*
Monica Lee, Yale University
Tvisha Misra, Sickkids
Ajit Muley, Columbia University Medical Center
David Sweet, Case Western Reserve University School of Medicine
Jian-Guo Wang, Brigham and Women's Hospital, Harvard Medical School
Yinyu Wu, Yale University

General Sessions:
Dario Riascos-Bernal, Albert Einstein College of Medicine
Keith Strand, University of Colorado Anschutz Medical Campus*

NAVBO Merit Award:
Amber Stratman, NICHD/NIH*
*Not pictured.
Congratulations to the  Outstanding Poster Award Recipients:
De Yu Mao, University of Illinois at Chicago
Joseph Fowler, Yale University
Gael Genet, Yale University
Jessica Hensel, University of Connecticut
Sofia Nordling, Stanford University School of Medicine
(not pictured: Joshua Berus, Brown University, Kristina Haase, Massachusetts Institute of Technology, and Pieter Norden, Northwestern University)
Lessons Learned
Dr. John C. Chappell
The following is a portion of Dr. Chappell's reflections on his early career experiences. You will find the full version on the NAVBO website.
Maintain a work-life balance- Many careers can consume you, and a career in academic science can certainly tip the work-life balance towards working almost continuously. What started out as a passion and a curiosity to discover new things about the vascular system can quickly turn into seemingly endless grant writing, manuscript preparation, e-mail replies, and so on. I would urge new independent investigators to work hard on their science, but to also find the aspects of life that provide rest and reinvigoration outside of their science and the workplace. Striving for and maintaining that work-life balance seems to be a critical skill to help avoid burnout and sustain you through the highs and lows of grant/paper reviews and all of the other challenges you will face.
Find your place of Zen- In reading the Lessons Learned contributions from my colleagues, one theme emerges very clearly-this career path is full of many difficult challenges. Publishing, funding, managing a lab, etc. In the midst of the ups and downs, I have found that staying connected to the science and keeping my hands on the experiments has been incredibly helpful. My place of Zen is at my confocal, taking high-resolution images of biological phenomena - it has been my shelter during the storms of never-ending demands. Find the part of science that fueled your love of what you do, and fight to keep that as part of your schedule. I try to use my confocal at least once every week or two. It helps clear my mind and reinvigorates me, while also inspiring new ideas and avenues for research. I encourage you to find that quiet place of enlightenment, free from worrying about what you cannot change.
Be focused but stay curious- When I started down the path of a career in academic science, one aspect I enjoyed the most was that curiosity was encouraged. As many of my colleagues have cautioned me, staying focused is important for building a critical mass of productivity in a particular area. But I would encourage a balance. Write down your curiosities. One day you may have the personnel and funding to pursue an idea you initially thought was a tangent, but it could develop into an unexpected discovery.
 Read more from Dr. Chappell on aiming for clarity, seeking out mentoring, and daring to be provocative.

Lab of the Month
The Lab of Dr. John C. Chappell

This month we are highlighting the lab of Dr. John C. Chappell, an Assistant Professor in the Department of Biomedical Sciences , at Virginia Tech Carilion Research Institute. Find out more about Dr. Chappell and his lab at 
Vascular Biology T-Shirt!!!
Support NAVBO's Educational Activities
Your purchase of one of these "snazzy" shirts (or mug!) will help support Vasculata, webinars, meetings, courses and travel awards.

Purchase a short sleeve tee, a long sleeve tee, a hoodie or a mug at  Shirts are available in white, gray, navy and black.  Buy some for your whole lab! Shirts start at $21.99.

Items will be made to order every five days, but don't wait, order yours today!
So far our profit is over $200 -
thanks to all who have already ordered a shirt!
Spotlight on Trainees
Message for new PhDs: hang on, brighter days ahead
Vimal Patel, writing in The Chronicle of Higher Education, reports results of a recent survey in which majorities of doctoral degree recipients feel that their Ph.D. programs prepared them well for their current jobs, whether academic or otherwise.  The survey, conducted by the Council of Graduate Schools and based on 882 responses, was focused on doctoral graduates in the humanities, but PhD earners in the life sciences wrestle with similar issues.  Within three years of completing their Ph.D. programs, nearly 80% of those with academic jobs felt very or extremely well-prepared for their current jobs; 52% in nonacademic jobs felt similarly sanguine.  Happily, that gap between academic (83%) and non-academic respondents (69%) narrowed as the time post-PhD lengthened.
Member News
Members of NAVBO attending American Heart Scientific Sessions in Chicago, you are cordially invited by the early career committee of the Peripheral Vascular Disease Council to attend a friend-raiser cocktail reception at the Woven & Bound Bar located in the lobby level of the Marriott Marquis Hotel on Saturday, November 10th from 5-7pm. The council dinners will be that evening, and if you are interested in attending, there are still some tickets available for the PVD dinner that night. This event is usually sold out prior to the event, so please purchase ahead of time if planning to attend. For those procrastinators, there will also be first come first serve onsite registration for the dinner at the Marriott Marquis. 
For those already registered for Scientific Sessions, please click on "registration" to add the dinner at the following link: 
Please contact Luke Brewster (NAVBO Membership Chair) with any questions:

Welcome to our New Members:
Anca Dana Dobrian, Eastern Virginia Medical School 
Irene Evans, Rochester Institute of Technology
Lang Ho Lee, Brigham and Women's Hospital
Emily Meredith, UCONN Health Center
Zoe Vogel, Columbia University Medical School

If you have news to share with your colleagues, send it to
 Recent Publications by NAVBO Members

Role of age, Rho-kinase 2 expression, and G protein-mediated signaling in the myogenic response in mouse small mesenteric arteries
Physiological Reports
The myogenic response (MR) and myogenic tone (MT) in resistance vessels is crucial for maintaining peripheral vascular resistance and blood flow autoregulation. Development of MT involves G protein-coupled receptors, and may be affected by aging.  Read more


Erythro-myeloid progenitors contribute endothelial cells to blood vessels
The earliest blood vessels in mammalian embryos are formed when endothelial cells differentiate from angioblasts and coalesce into tubular networks.  Read more


Endothelial Regeneration of Large Vessels Is a Biphasic Process Driven by Local Cells with Distinct Proliferative Capacities
Cell Stem Cell
The cellular and mechanistic bases underlying endothelial regeneration of adult large vessels have proven challenging to study.  Read more


Is Intraplaque Hemorrhage a Decoration or a Driver?
JACC: Basic to Translational Science
Contemporary advances in high-throughput screening of biological samples have added unbiased screens to the classical candidate approach for implicating mediators in various disease states.  Read more


Relationship of Interleukin-1β Blockade With Incident Gout and Serum Uric Acid Levels: Exploratory Analysis of a Randomized Controlled Trial
Annals of Internal Medicine
Background: Although studies have shown that interleukin-1β (IL-1β) inhibitors can shorten gout attacks, whether they can prevent gout attacks is unclear.  Read more


Impaired tumor growth and angiogenesis in mice heterozygous for Vegfr2 (Flk1)
Scientific Reports
VEGF signaling through its tyrosine kinase receptor, VEGFR2 (FLK1), is critical for tumor angiogenesis. Previous studies have identified a critical gene dosage effect of VegfA in embryonic development and vessel homeostasis, neovascularization, and tumor growth, and potent inhibitors of VEGFR2 have been used to treat a variety of cancers.  Read more


Mechanisms of Connexin-Related Lymphedema: A Critical Role for Cx45, but not Cx43 or Cx47, in the Entrainment of Spontaneous Lymphatic Contractions
Circulation Research
Rationale: Mutations in GJC2 and GJA1, encoding Cxs (connexins) 47 and 43, respectively, are linked to lymphedema, but the underlying mechanisms are unknown.  Read more


Estrogen Inhibits LDL Transcytosis by Human Coronary Artery Endothelial Cells via GPER and SR-BI
Arteriosclerosis, Thrombosis, and Vascular Biology
Objective - The atheroprotective effects of estrogen are independent of circulating lipid levels. Whether estrogen regulates transcytosis of LDL (low-density lipoprotein) across the coronary endothelium is unknown.  Read more


Pathogenic variant in EPHB4 results in central conducting lymphatic anomaly
Human Molecular Genetics
Central conducting lymphatic anomaly (CCLA) is one of the complex lymphatic anomalies characterized by dilated lymphatic channels, lymphatic channel dysmotility and distal obstruction affecting lymphatic drainage.  Read more

Industry News
"Million Hearts 2022" seeks to reduce mortality in cardiovascular disease  
The profound advances in prevention, diagnosis and treatment of heart and peripheral vascular diseases over the last half century resulted in a celebrated drop in rates of death owing to cardiovascular disorders. Now, this drop has abated and even changed course in adults aged 35 to 64, where deaths attributable to heart disease are on the increase. In view of this shift in medical fortunes, the US Centers for Disease Control and Prevention has launched Million Hearts 2022, emphasizing adoption of, and adherence to, those measures already proven to improve and sustain cardiovascular health. Janet Wright, MD, and her CDC colleagues note in JAMA that persistence of multiple behaviors and other factors stand in the way of progress, notably physical inactivity, smoking, uncontrolled high blood pressure, and hypercholesterolemia.

What makes science 'hard' in an era when the very value and nature of evidence is questioned?
French philosopher Bruno Latour created a stir in the late 20th century by positing that scientific facts were "social constructions," that is, created by scientific research rather than standing freely and objectively apart from the investigation that reveals said facts.  The "realists" who countered this view feared that constructionists would undermine scientific progress, legitimizing creationism and encouraging the anti-vaccine movement.  The debate produced memorable salvos, including an invitation from physicist Alan Sokal that Latour step out his 21st-floor window if the laws of physics were nothing more than social conventions.  In the New York Times Magazine, Ava Kofman explores the implications of Latour's legacy for the present post-fact era.

Cardiovascular aspects of endocrine disorders highlighted
The Endocrine Society has joined forces with the medical information system MedPage Today and the American College of Cardiology (ACC) to create an online resource that brings to the foreground leading research exploring important connections between cardiovascular and endocrine diseases.  Dubbed the Cardio-Endo Connection, the web presence aims to inform both primary care physicians and endocrine and CV specialists about important mutual concerns.  The site's inaugural offerings probe cardiovascular benefits of modified metformin therapy in Type 2 diabetes as well as management of primary aldosteronism.
Job Postings
Calendar of Events
Nov. 2, 2018
20th Annual Boston Angiogenesis Meeting
April 11 - 13, 2019
11th Congress of the Vascular Access Society
May 30 - June 1, 2019
Lymphatic Forum 2019
July 6 - 10, 2019
International Society on Thrombosis and Hemostasis Congress 2019
Oct. 27 - 31, 2019
Vascular Biology 2019
Sept. 9 - 12, 2020
IVBM 2020
North American Vascular Biology Organization | |
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Germantown, MD 20874-2211