August 4, 2016 
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NAVBO members receive discounts on registration to IVBM 2016
Vasculata 2016
Uppsala University
University of Pennsylvania
August 15-17
Look inside the IVBM Virtual Conference Bag

Lymphatic Forum
in Chicago, IL
June 8-10, 2017

Vascular Biology 2017
Monterey, CA
October 15-19 
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Meet our New Council Members
Rosemary J. Akhurst, Ph.D., Professor
Helen Diller Family Comprehensive Cancer Center and Department of Anatomy  
University of California at San Francisco
Dr. Akhurst received a BSc (Hons) in Biochemistry from Imperial College, London, UK and a PhD from the Beatson Institute for Cancer Research in Scotland, UK. After undertaking post-doctoral research as an EMBO fellow at Caltech, Pasadena, she returned to the UK where she held Faculty positions in Biochemistry and Genetics at the University of London (Imperial College) and at the University of Glasgow UK. After a brief period in Biotech (Onyx Pharmaceuticals) she returned to academia at UCSF, where she is now full professor and Director of the UCSF HDFCCC Preclinical Therapeutics Core Facility.
Dr. Akhurst is internationally recognized for her work investigating the in vivo functions and genetic regulation of TGF- β signaling during embryonic development and in tumorigenesis. Her lab reported the first evidence of the essential role that TGF- β 1 plays in vascular development in vivo, and has gone on to genetically map and clone modifiers of TGF- β signaling that regulate vascular and cancer biology. She also studies molecular pathological mechanisms in Hereditary Hemorrhagic Telangiectasia, a vascular dysplasia caused by mutations in ENG or ACVRL1. Additionally, Dr. Akhurst's lab was the first to demonstrate the biphasic action of TGF- β signaling as both early tumor suppressor but late tumor promoter during tumorigenesis in vivo, and the lab has gone on to undertake preclinical studies to investigate the use and mechanisms of action of pharmaceutical TGF- β signaling blockers as therapeutics for cancer. Several such drugs are now undergoing clinical trials for oncology.
Dr. Akhurst has been the recipient of several academic scholarships and prizes during her training. She has served on many Committees and Review Boards in the US and the UK, including BSDB and AACR and she currently serves on the Meritorious Awards Committee of NAVBO. She is also on the Editorial Board of the Royal Society's Open Biology.
Record Number of Abstracts Received

592 Abstracts Received    

for the 19th International Vascular Biology Meeting 
Boston - October 30-November 3

You've got to be there! 


Early bird registration deadline - August 15
Hotel reservations - October 8
Award Opportunity
Warren Alpert Foundation Prize 
The Warren Alpert Foundation invites nominations for the 2017 Warren Alpert Foundation Prize. Nominations should be made for scientific achievements that have led to the prevention, cure, or treatment of human disorders or for research for seminal scientific research findings that holds great promise to change our ability to treat disease.
The unrestricted cash award accompanying the prize is U.S. $500,000, a citation and plaque. The recipient(s) of the 2017 Warren Alpert Foundation Prize will also participate in a special symposium in their honor at Harvard Medical School. Nominations are accepted from academic institutions, centers of research, government, or other biomedical institutions from around the world. Self-nominations are not accepted. To nominate, please visit the Warren Alpert Foundation Prize nomination page at . The deadline for receipt of nominations is October 31, 2016.
Member News
Welcome our new members:
Michael Abadier, La Jolla Institute for Allergy and Immunology
Rui Benedito, CNIC
Sarvesh Chelvanambi, Indiana University School of Medicine
Audrey Cleuren, University of Michigan
Brian Coon, Yale University School of Medicine
Kirsten Coupland, Karolinska Institutet
Matthew Cribb, Georgia Institute of Technology
Lucy Lin Cui, The Roslin Institute, University of Edinburgh
Brandee Decker, Albany Medical College
Carsten Deppermann, The Snyder Institute for Chronic Diseases
Vanessa Frodermann, Massachusetts General Hospital
Jesus Gómez Escudero, Centro Nacional de Investigaciones
Rashmi Hegde, Cincinnati Children's Hospital Medical Center
Magda Hernandez, CINVESTAV-IPN
Xiaojia Huang, The University of Illinois at Chicago
Il Ho Jang, Pusan National University
Jan Kraehling, Yale University
Konda Babu Kurakula, Leiden University Medical Center
Edyta Kus, Jagiellonian Centre of Experimental Therapeutics
Kamil Kus, Jagiellonian Centre of Experimental Therapeutics
Callie Kwartler, University of Texas Health Science Center at Houston
Jia Li, Centenary Institute
Lingfei Luo, Southwest University
Ashley Mackey, Schepens Eye Research Institute
Vicky MacRae, University of Edinburgh
Kevin Mangum, University of North Carolina at Chapel Hill
Jatin Patel, The University of Queensland
Maulin Patel, University of Oklahoma Health Science Center
Habibunnabi Rahman, Boston Children's Hospital
Teresa Sanchez, Weill Cornell Medical College
Yogev Sela, The Weizmann Institute
Adama Sidibé, University of Geneva
Matthew Siviski, Maine Medical Center Research Institute
Marta Smeda, Uniwersytet Jagiellonsk
Magdalena Sternak, Jagiellonian Centre for Experimental Therapeutics
Hiu Gwen Tsang, The Roslin Institute
Sofia Urner, Heinrich Heine University
Martijn van der Ent, University of Michigan
Inge Margaretha van der Werf, Boston Children's Hospital-Harvard Medical School
Branka Vulesevic, Institut de Cardiologie de Montréal
Ying Wang, University of British Columbia
Alanna Watson, The University of Western Ontario
Wen Wu, Albany Medical College
Hideki Yamamoto, University of Wisconsin
Yvette Zarb, University of Zurich
Ze Zheng, Columbia University

If you have news to share with your colleagues, send it to
Spotlight on Trainees
Congratulations to our GRC Travel Award Recipients
NAVBO's Trainee Travel Awards for the Gordon Research Conference on Endothelial Cell Phenotypes in Health & Disease were awarded to Austin McDonald of the UCLA-Caltech Medical Scientist Training Program for his abstract entitled, "Mechanisms of Endothelial Regeneration," and Emma Watson of the Walter and Eliza Hall Institute of Medical Research in Australia for her abstract entitled, "Pro-survival protein MCL1 is essential for endothelial cell survival during angiogenesis."
Product Showcase
Excellence from the European Heart Journal 
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 Recent Publications by NAVBO Members

Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction
Microvascular injury (MVI) after coronary ischemia-reperfusion is associated with high morbidity and mortality. Both ischemia and reperfusion are involved in MVI, but to what degree these phases contribute is unknown. Understanding the etiology is essential for the development of new potential therapies.  Read more

The F-BAR protein pacsin2 inhibits asymmetric VE-cadherin internalization from tensile adherens junctions
Nature Communications
Vascular homoeostasis, development and disease critically depend on the regulation of endothelial cell-cell junctions. Here the authors uncover a new role for the F-BAR protein pacsin2 in the control of VE-cadherin-based endothelial adhesion.  Read more

Endothelial cell survival during angiogenesis requires the pro-survival protein MCL1
Cell Death & Differentiation
Angiogenesis is essential to match the size of blood vessel networks to the metabolic demands of growing tissues. While many genes and pathways necessary for regulating angiogenesis have been identified, those responsible for endothelial cell (EC) survival during angiogenesis remain largely unknown.  Read more

NADPH Oxidase 2 Regulates LPS-induced Inflammation and Alveolar Remodeling in the Developing Lung
American Journal of Respiratory Cell and Molecular Biology
Sepsis is associated with alveolar simplification manifesting as Bronchopulmonary Dysplasia (BPD) in premature infants. The redox-dependent mechanisms underlying sepsis-induced inflammation and alveolar remodeling in the immature lung remain unclear.  Read more

Selective serotonin reuptake inhibitor (SSRI) exposure constricts the mouse ductus arteriosus in utero
The American Journal of Physiology - Heart and Circulatory Physiology
Use of selective serotonin reuptake inhibitors (SSRIs) is common during pregnancy. Fetal exposure to SSRIs is associated with persistent pulmonary hypertension of the newborn (PPHN), however a direct link between the two has yet to be established.  Read more

Job Postings
Job Title
University of California, San Francisco
San Francisco, CA
Postdoctoral Fellowship
University of Pittsburgh
Pittsburgh, PA
Yale University School of Medicine
New Haven, CT
Postdoctoral Fellow
Blood Center of Wisconsin
Milwaukee, WI
Calendar of Events
Aug. 15-18 Vasculata 2016
Sept. 7-10 ISACB - 15th Biennial Meeting
Sept. 26-28 Perspectives in Vascular Biology
Oct. 30 - Nov. 3 19th International Vascular Biology Meeting
Nov. 13-16 American Society for Matrix Biology Biennial Meeting
June 8 - 10 Lymphatic Forum 2017
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Please note - more sessions and more information will continue to be added.
Eye Opener Sessions have now been added.

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Germantown, MD 20874-2211