February 8, 2018
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  20th IVBM   Helsinki, Finland   June 3-7, 2018
Registration and Abstract Submission now open! 


Vasculata 2018 
St. Louis, MO
July 23 - 26, 2018

Vascular Biology 
Newport, RI 
October 14-18, 2018 
Next webinar is March 8
Corporate Partners
Corporate Members
Affiliated Journals
Cardiovascular Medicine
What's on the Web?
Listings of Training Programs in the US
There are currently 55 listings. Go to http://www.navbo.org/resources/trainingprograms

Add your training program to the list - contact Anita@navbo.org
Shop at Amazon?   
Help Support NAVBO 
Use this link to shop for everyone and everything
  smile.amazon.com/ch/52-1917956 and Amazon will donate to NAVBO  
Registration NOW OPEN!
Register for Vascular Biology and Vasculata 
Registration is now open for our annual meeting, Vascular Biology (October 14-18 in Newport, RI).  Go to www.navbo.org/vb2018

You can also register now for Vasculata 2018 (July 23-26, St. Louis, MO).  Go to www.navbo.org/vasculata

Note about the registration fees.  We have not raised the registration fees, however, we are now adding a 3% surcharge to any credit card purchase in order to cover the cost of credit card transactions.   Why are we doing this?  In 2017, we incurred $4,406 in credit card expenses for just the annual meeting and another $730 for Vasculata.  In 2015, the total was $6,630.  In 2016, we paid over $12,000 in fees for the IVBM.  If you pay by check, you can avoid this surcharge.  Rather than simply raising all registration fees, NAVBO council and meeting organizers believe this is a fairer way to handle this expense.

You can also submit an abstract for either meeting. Go to the appropriate meeting web site.
Last Call - Host Vasculata in 2019
Vasculata could be held at your institution!
If you are interested in hosting Vasculata at your institution, please see the information at http://www.navbo.org/vasculata-host.
Applications are due February 20.
Plan to Attend the IVBM
NAVBO is Encouraging Members to Attend the IVBM
In 2016, 40% of the attendees at the 19th International Vascular Biology Meeting in Boston were from outside North America.  However, I'm told that less than 10% of the attendees at the 2014 IVBM in Japan and the 2012 IVBM in Germany were from North America.  Let's change that statistic!  The program for the meeting is available, registration is open and Finnair is giving discounts to those traveling to the IVBM.  Plan now to attend and submit an abstract. Let's change things up!

Trainee Members Apply for a Travel Award
NAVBO is supporting more travel awards to this year's IVBM than for previous  IVBMs held outside of North America - 8 awards valued at $1,200 each.  Find out how you can apply for an award at http://www.navbo.org/awards/trainee-awards/ivbm-travel-awards
NIH - Call for Applications
NHLBI would like to bring to your attention the following recently published Funding Announcements with rapidly approaching deadlines:

Long Non-coding RNA in Cardiovascular, Lung, Blood, and Sleep Research (R01). See NHLBI Long Non-coding RNA RFA
  to read more about this exciting research opportunity. Application deadline: March 30, 2018
Contact: Michelle Olive, PhD, NHLBI, phone: 301-443-7933

The Human BioMolecular Atlas Program has three calls open for applications
NHLBI is seeking vascular biologists to participate in this program.  The current open applications are:

Tissue Mapping Centers for The Human BioMolecular Atlas Program (U54 Clinical Trial Not allowed) Deadline March 2, 2018 (letter of intent due Feb 1, but not required)

Transformative Technology Development for The Human BioMolecular Atlas Program (UG3/UH3 Clinical Trial Not Allowed) Deadline March 2, 2018 (letter of intent due Feb 1, but not required)

  The Human BioMolecular Atlas Program (HuBMAP) Integration, Visualization and Engagement (HIVE) Initiative (OT2 Clinical Trials Not Allowed)
Letter of intent - required! - by Feb 28. Deadline April 16, 2018 (opens March 1)

See https://commonfund.nih.gov/HuBMAP/funding for more information or contact HUBMAP@mail.nih.gov with a ny questions.

A video recording from a previously held webinar provides an overview of the program and includes information about RFA-RM-17-025 and  RFA-RM-17-027.
Lab of the Month
The Lab of Dr. Kishore Wary
This month we are highlighting the lab of Dr. Kishore Wary, an Associate Professor of Pharmacology, who organized an extremely successful Vasculata last July at his institution, the University of Illinois at Chicago. Find out more about Dr. Wary and his lab at http://www.navbo.org/membership/members-labs/673-lab022018.
Spotlight on Trainees
In the market for a post-doctoral experience?
One of the toughest decisions with which PhD students must grapple as they approach completion of their graduate study concerns their post-doctoral fate.  Stay in a familiar discipline or explore a new field? Stay domestic or venture internationally?  Industry or academe?  Work under an individual patron or as part of a training program?  Fortunately, a variety of resources exist to help soon-to-be PhDs identify the available options.  Some of these information sources have a distinct global perspective, such as that assembled informally by eLife Ambassadors. Closer to home, NAVBO's Education Committee has compiled an online listing of Training Programs in Vascular Biology that includes contact information and descriptions of program scope and mission.  The list, which is frequently updated, is grouped according to the host institution's geographic location.
Member News
Welcome to our New Members:
Cassidy Blackburn, Louisiana State University Health Sciences Center
Dunpeng Cai, University of Georgia
Sunitha Chandran, Louisiana State University Health Sciences Center
Gangjian Qin, University of Alabama at Birmingham
Yang Zhang, Uppsala University

If you have news to share with your colleagues, send it to membership@navbo.org.
 Recent Publications by NAVBO Members

Fibrinogen-like protein-2 causes deterioration in cardiac function in experimental autoimmune myocarditis rats through regulation of programmed death-1 and inflammatory cytokines
Programmed death-1 (PD-1) plays an important role in protecting against inflammation and myocyte damage in T-cell-mediated myocarditis. To understand whether fibrinogen-like protein-2 (FGL2) can affect the role of the PD-1/PD-L1 pathway in experimental autoimmune myocarditis (EAM), we investigated cardiac function in EAM rats over-expressing FGL2.  Read more


Integrating light-sheet imaging with virtual reality to recapitulate developmental cardiac mechanics
Journal of Clinical Investigation Insight
Currently, there is a limited ability to interactively study developmental cardiac mechanics and physiology. We therefore combined light-sheet fluorescence microscopy (LSFM) with virtual reality (VR) to provide a hybrid platform for 3D architecture and time-dependent cardiac contractile function characterization.  Read more


Disturbed Flow Promotes Arterial Stiffening Through Thrombospondin-1
BACKGROUND: Arterial stiffness and wall shear stress are powerful determinants of cardiovascular health, and arterial stiffness is associated with increased cardiovascular mortality.  Read more


Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow
Low and disturbed blood flow drives the progression of arterial diseases including atherosclerosis and aneurysms. The endothelial response to flow and its interactions with recruited platelets and leukocytes determine disease progression.  Read more


Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits
Arteriosclerosis, Thrombosis, and Vascular Biology
OBJECTIVE: Gene therapy that expresses apo A-I (apolipoprotein A-I) from vascular wall cells has promise for preventing and reversing atherosclerosis.  Read more


A computational analysis of pro-angiogenic therapies for peripheral artery disease
Integrative Biology
Inducing therapeutic angiogenesis to effectively form hierarchical, non-leaky networks of perfused vessels in tissue engineering applications and ischemic disease remains an unmet challenge, despite extensive research and multiple clinical trials.  Read more


Human macrophages differentially produce specific resolvin or leukotriene signals that depend on bacterial pathogenicity
Nature Communications
Proinflammatory eicosanoids (prostaglandins and leukotrienes) and specialized pro-resolving mediators (SPM) are temporally regulated during infections.  Read more


Resolvins suppress tumor growth and enhance cancer therapy
Journal of Experimental Medicine
Cancer therapy reduces tumor burden by killing tumor cells, yet it simultaneously creates tumor cell debris that may stimulate inflammation and tumor growth.  Read more


Potent anti-inflammatory and pro-resolving effects of anabasum in a human model of self-resolving acute inflammation
Clinical Pharmacology and Therapeutics
Anabasum is a synthetic analogue of Δ8 - tetrahydrocannabinol (THC)-11-oic acid that in pre-clinical models of experimental inflammation exerts potent anti-inflammatory actions with minimal CNS cannabimimetic activity.  Read more


New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration
Molecular Aspects of Medicine
While protective, the acute inflammatory response when uncontrolled can lead to further tissue damage and chronic inflammation that is now widely recognized to play important roles in many commonly occurring diseases, such as cardiovascular disease, neurodegenerative diseases, metabolic syndrome, and many other diseases of significant public health concern.  Read more

Industry News
US leadership in science and innovation under the microscope
The US has dropped to 11th place in the 2018 Bloomberg Innovation Index, giving way to France and Israel.  The index scores countries using multiple criteria, including research and development spending and concentration of high-tech public companies.  The slip in the US standing traces to a slide in the post-secondary, or tertiary, education-efficiency metric, which includes the share of new science and engineering graduates in the labor force.  China, already a major force in life science research, ranks at #19 on the 2018 Bloomberg list.  China has overtaken the US in total numbers of academic articles published annually and appears, according to  NSF estimates, on track to outspend the US in R&D within a matter of years.  The NSF evaluators, however, note that the collaborative and international nature of life science research should allow individual countries to focus on research priorities rather than on competition.

New Voices in Sciences, Engineering and Medicine
The National Academies of Sciences, Engineering, and Medicine announces a pilot program, "New Voices in Sciences, Engineering and Medicine," supported by the Gordon and Betty Moore Foundation, to recognize early-career SEM leaders engaged in articulating, communicating, and addressing worldwide challenges. The program is currently seeking nominations of exceptional young leaders who have demonstrated a commitment to leadership and serving the SEM community through science policy, communication, education, outreach, international or interdisciplinary engagement, leadership development, and other activities. Nominations may be submitted through February 16, 2018.

New smartphone tool smooths the path for air travelers
Our members are on the go, heading to professional meetings, invited talks, or grant review sessions.  GoogleMaps, Waze, and other smartphone apps can alert travelers to traffic conditions around the airport, but what about those inevitable lines at security once inside the terminal?  The travel app TripIt Pro ($49 a year) now has a feature that estimates wait times through security at several major US airports, and the vendor expects dozens of the nation's busiest airports will be included by year's end. Interior maps of the airport are displayed, routing the traveller to shortest lines. The app interacts with sensors at airport security checkpoints, providing continual updates to subscribers.  

Job Postings
Calendar of Events
Feb. 25 - March 1, 2018
Keystone Symposia: Vascular Biology and Human Diseases: From Molecular Pathways to Novel Therapeutics
March 16 - 17, 2018
10th Anniversary Symposium on Vascular Anomalies
April 8 - 12, 2018
Keystone Symposia - Organs- and Tissues-on-Chips
May 31 - June 1, 2018
22nd International Workshop on Vascular Anomalies
June 3 - 7, 2018
20th International Vascular Biology Meeting
June 9 - 12, 2018
XVIII International Symposium on Atherosclerosis
July 18 - 21, 2018
ISTH SSC 2018 Meeting
Sept. 9 - 13, 2018
11th World Congress of Microcirculation (WCM2018)
North American Vascular Biology Organization | bernadette@navbo.org | http://www.navbo.org
18501 Kingshill Road
Germantown, MD 20874-2211