October 4, 2018
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Vascular Biology 
Newport, RI 
October 14-18, 2018 

Lymphatic Forum 2019
Austin, TX
May 31 - June 1, 2019

Vasculata 2019
Medical College of Wisconsin
July 13 - 18, 2019

Corporate Partners
Corporate Members

VB2018 Supporters

VB2018 Exhibitors

Affiliated Journals
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Help Support NAVBO 
Use this link to shop for everyone and everything
  smile.amazon.com/ch/52-1917956 and Amazon will donate to NAVBO 
Celebrating 25 Years!
Call for Volunteers!
NAVBO was incorporated in December 1994 and we are about to celebrate our 25th Anniversary!!
Everything is still in the planning stages.  If you would like to join the 25th Anniversary Committee, led by Drs. Cleaver and Galis, and help us initiate ways to celebrate and recognize our members, contact info@navbo.org.
We'd love to hear your ideas! 
Vascular Biology 2018
Final Program Available on Web Site
The complete program is now available on our web site; it includes all presentations, go to http://www.navbo.org/events/vb2018/schedule .

Also, take a look at the abstracts being presented.
Register for the meeting at http://www.navbo.org/events/vb2018/register 
Online registration will only be open until October 11 
Congratulations to our Travel Award Recipients:
Vascular Inflammation Workshop:
Mabruka Alfaidi, LSU Health Sciences Center - Shreveport
Thanh Theresa Dinh, Stanford University
Eric Engelbrecht, Boston Children's Hospital
Rajat Gupta, Brigham and Women's Hospital
Hideyuki Higashi, Brigham and Women's Hospital
Peter Kip, Brigham and Women's Hospital/Harvard Medical School
Sarah-Anne Nicholas, University of Connecticut Health
Brian Sansbury, Harvard Medical School/Brigham and Women's Hospital
Shawn Veitch, University of Toronto

Biology of Signaling in the Cardiovascular System Workshop:
Nicholas Chavkin, University of Virginia
Julius Decano, Brigham and Women's Hospital
Melanie Hofmann, Hannover Medical School
Nadiya Khyzha, University Health Network
Monica Lee, Yale University
Tvisha Misra, Sickkids
Ajit Muley, Columbia University Medical Center
David Sweet, Case Western Reserve University School of Medicine
Jian-Guo Wang, Brigham and Women's Hospital, Harvard Medical School
Yinyu Wu, Yale University

General Sessions:
Dario Riascos-Bernal, Albert Einstein College of Medicine
Keith Strand, University of Colorado Anschutz Medical Campus

NAVBO Merit Award:
Amber Stratman, NICHD/NIH

Vascular Biology T-Shirt!!!
Support NAVBO's Educational Activities
Your purchase of one of these "snazzy" shirts (or mug!) will help support Vasculata, webinars, meetings, courses and travel awards.

Purchase a short sleeve tee, a long sleeve tee, a hoodie or a mug at  https://teespring.com/vascular-biology-t-shirt.  Shirts are available in white, gray, navy and black.  Buy some for your whole lab! Shirts start at $21.99.

Items will be made to order every five days, but don't wait, order yours today!
So far our profit is over $200! Can we reach $1,000?!
Thanks to all who have already ordered a shirt
HIV/AIDS and Vascular Diseases
NHLBI-supported efforts at the interface of HIV/AIDS and vascular diseases
Newly-elected NAVBO Councilor, Zorina Galis, PhD, who serves as Chief of the Vascular Biology and Hypertension Branch at the National Heart, Lung and Blood Institute, has shared news of
opportunities in HIV-related research of potential interest to NHLBI. The NHLBI HIV/AIDS Program aims to promote research, training, and educational programs in the areas of HIV-related heart, lung, blood, and sleep disorders, as well as blood-based therapies for prevention or treatment. As is the case with other NIH Centers and Institutes, the NHLBI recognizes that strategic research in these areas has the potential to generate insights that enhance the survival and quality of life of patients living with HIV; this knowledge that may also benefit all patients with heart, lung, blood, and sleep disorders. Those interested in exploring research avenues that bridge vascular biology and HIV/AIDS are invited to tune in to the series of NHLBI webinars that showcase the work of funded investigators or visit HIV-related sites for the NHLBI units focused on Cardiovascular Sciences , Lung Diseases , Blood Diseases , and Translational Research and Implementation .
Funding Opportunities from NHLBI
NHLBI Funding Opportunity - Deadline Approaching
The Vascular Biology and Hypertension Branch of NHLBI is seeking applications to the following funding opportunity:
RFA-HL-17-22: Maximizing the Scientific Value of the NHLBI Biorepository: Scientific Opportunities for exploratory Research (R21).

This funding opportunity is to support meritorious exploratory research relevant to the NHLBI mission using the biospecimen collections that are stored in the NHLBI Biorepository and that are available through BioLINCC.  

The next due date for non-AIDS applications is October 17, 2018. Requests were due to BioLINCC on September 26, 2018 in order to be eligible to receive a Letter of Availability by this due date.

The next due date for AIDS applications is January 7, 2019. Requests must be submitted to BioLINCC no later than December 17, 2018 in order to be eligible to receive a Letter of Availability by this due date.

For more information on RFA-HL-17-022 please visit:
To view available biospecimen collections and initiate a request, please visit:  
Spotlight on Trainees
Quality mentoring of PhD scientists crucial for success in career launch
Andrea M. Zimmerman from the Office of Continuing Medical Education at the University of Virginia has published "Navigating the path to a biomedical science career" in PLoS One (9/7/18), examining the multifactorial nature of PhD trainees' experiences in the biomedical sciences and how they approach their career choices.  It is well known that the number of newly-minted life science PhDs exceeds the number of opportunities in academe. Using social cognitive career theory and data gleaned from case studies, the author concludes that mentoring relationships with faculty are key to successful navigation of career paths in a challenging employment marketplace.
Member News
Studies, published in Nature in September from the laboratory of Christiana Ruhrberg at University College London, describe development of a supplemental source of endothelial cells recruited into pre-existing embryonic vasculature after differentiation from erythro-myeloid progenitors, the precursors of erythrocytes, megakaryocytes and macrophages that originate in the yolk sac. Dr. Ruhrberg's findings were highlighted by the British Heart Foundation, a sponsor of the research, and were picked up by the BBC as well.

Welcome to our New Members:
Olga Cherepanova, Lerner Research Institute, Cleveland Clinic
Jingbo Dai, Northwestern University
Mitra Esfandiarei, Midwestern University
Junhao Hu, Interdisciplinary Research Center on Biology and Chemistry
Laurel Lee, Brigham and Women's Hospital
Narsa Machireddy, Northwestern University

If you have news to share with your colleagues, send it to membership@navbo.org.
 Recent Publications by NAVBO Members

Cerebral Cavernous Malformations Develop Through Clonal Expansion of Mutant Endothelial Cells
Circulation Research
Rationale: Vascular malformations arise in vessels throughout the entire body. Causative genetic mutations have been identified for many of these diseases; however, little is known about the mutant cell lineage within these malformations.  Read more


Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic Stroke
Cell Reports
Cerebrovascular malformations (CVMs) affect approximately 3% of the population, risking hemorrhagic stroke, seizures, and neurological deficits. Recently Ras mutations have been identified in a majority of brain arterio-venous malformations.  Read more


Interleukin-1β has atheroprotective effects in advanced atherosclerotic lesions of mice
Nature Medicine
Despite decades of research, our understanding of the processes controlling late-stage atherosclerotic plaque stability remains poor.  Read more


Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm in Mouse and Humans
Circulation Research
Rationale: Abnormal mechanosensing of smooth muscle cells (SMCs) resulting from the defective elastin-contractile units has been suggested to drive the formation of thoracic aortic aneurysms; however, the precise molecular mechanism has not been elucidated.  Read more


Irradiation abolishes smooth muscle investment into vascular lesions in specific vascular beds
Journal of Clinical Investigation Insight
The long-term adverse effects of radiotherapy on cardiovascular disease are well documented. However, the underlying mechanisms responsible for this increased risk are poorly understood.  Read more

Industry News
Broad Institute prevails in legal tussle for CRISPR patent rights
A four-year dispute over rights to CRISPR intellectual property has been settled.  In a September 10 ruling from the US Court of Appeals, the Broad Institute's patent was upheld, ending the challenge filed by UC Berkeley. The Broad patent claims use of CRISPR editing technology in eukaryotes, including plants and animals and thus is highly relevant to the spectrum of potential CRISPR/Cas9-based products currently in preclinical development. The patent settlement, while a setback for UC Berkeley, should clarify for all investigators the landscape for licensing.

Revenge of the unjustly pilloried
The 2018 Golden Goose Awards, celebrating investigators whose research supported by federal dollars was subjected to Congressional ridicule before being recognized as groundbreaking, have been announced. Awardees include Mahzarin Banaji, PhD, Anthony Greenwald, PhD, and Brian Nosek, PhD, for their work exploring the notion of implicit bias; Stanley Cohen, PhD, for his discovery of cytokines; and Bruce Glick, PhD, for his functional study of the Bursa of Fabricius in geese (no relation to the award).

The human genome: parts unknown
Carl Zimmer, writing in the New York Times, explores the ramifications of the investigational neglect suffered by huge portions of the human genome.  According to an analysis by Thomas Stoeger and colleagues at Northwestern University, some 5400 of our 20,000-ish recognized protein-encoding genes have never enjoyed the sunshine of publication, while a mere 2000 targets have been the subjects of 90% of recent scientific reports. Several factors contributing to this bias are discussed, including perceived disease relevance and ease of study, but the authors note that the situation is unlikely to change without major changes in the ways science is conducted or research direction incentivized.
Partner Network Advantage - New Job Board Feature
Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
Post your open position now at www.navbo.org/jobs! 
Job Postings
Calendar of Events
Oct. 14 - 18, 2018
Vascular Biology 2018
Nov. 2, 2018
20th Annual Boston Angiogenesis Meeting
May 30 - June 1, 2019
Lymphatic Forum 2019
Oct. 27 - 31, 2019
Vascular Biology 2019
Sept. 9 - 12, 2020
IVBM 2020
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Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25.   The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
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North American Vascular Biology Organization | bernadette@navbo.org | http://www.navbo.org
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