July 12, 2018
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Vasculata 2018 
St. Louis, MO
July 23 - 26, 2018
Supported in part by the:  

Vascular Biology 
Newport, RI 
October 14-18, 2018 

Lymphatic Forum 2019
Austin, TX
May 31 - June 1, 2019
Next webinar is August 2
Corporate Partners
Corporate Members

VB2018 Supporters
VB2018 Exhibitors

Affiliated Journals
NAVBO Privacy Policy
Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes. Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25.   The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
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Bring Vasculata to Your Institution!
If you can't come to Vasculata - have Vasculata come to you!

Bring the live streaming webcast of Vasculata to your institution

Have access to all five sessions:
    Blood Vessel Development
    ECM and Muscle in the Vessel Wall
    Core Physiology
    Cells of the Blood
    The Vasculature in Disease

Participate in live Q&A with 29 speakers within the web cast

Find out more, go to -

And you can still register for the live presentation and go to St. Louis!

Nominate a Colleague for a NAVBO Award
Seeking nominations for the Judah Folkman and Earl P. Benditt Awards.
These are NAVBO's most prestigious honors and each one reading this knows of several colleagues that are deserving of one of these honors.

The Earl P. Benditt Award recognizes an individual who has made an outstanding discovery or developed a concept that has been seminal to our understanding of vascular biology or pathology. More information is available here: http://www.navbo.org/awards/earl-p-benditt-award

The Judah Folkman Award in Vascular Biology is a mid-career award, and in recognition of the breadth of Dr. Folkman's interests and his many contributions to vascular biology is not limited to the field of angiogenesis, but encompasses the full range of original research in vascular biology. The recipient will have made a significant impact on the field through his/her original research accomplishments. Information can be found here: http://www.navbo.org/awards/judah-folkman-award

The submission deadline has been extended to July 27. Please honor your colleagues by nominating them for one of these prestigious awards.
NAVBO Council Election Results
Thank you to all the members that voted!

President-Elect:  Ondine Cleaver, UT Southwestern Medical Center
Councilors: Zorina Galis, NHLBI/NIH and Kristy Red-Horse, Stanford University

A special thank you to all the candidates for your willingness to serve NAVBO!
Next NAVBO Webinar
Sign up now for our August 2 Webinar with Michael Dellinger 

Our webinar attendees requested a webinar on Lymphatics, so please join us on August 2 at 1:00pm EDT for Dr. Dellinger's presentation, "Lymphatic Vessels and Vanishing Bones: Animal Models of Lymphatic Anomalies with Bone Involvement."  Dr. Dellinger is an Assistant Professor at UT Southwestern Medical Center. 

The webinar is sponsored by the Lymphatic Malformation Institute and the Lymphangomatosis & Gorham's Disease Alliance.

To register for the webinar please go to   http://www.navbo.org/events/webinars/718-webinar082018 

Please note: we will not be holding a July webinar  
Bioinformatics at Vascular Biology 2018!!!
Watch the webinar and see how bioinformatics can enhance your research (click on the slide to start the movie)

Attend Vascular Biology 2018 and register for this special session!
Bring your lap top and your favorite gene!!
Spotlight on Trainees
MIT's Robert Langer offers encouraging tips for early-career scientists
Robert Langer, a member of the MIT faculty since 1977, has had a spectacular career by any measure: he holds an Institute Professorship at MIT, has more than 1,400 published articles and 1,300 patents to his credit, and has earned more than 220 major professional awards including the US National Medal of Science. These achievements, however, came after what he regards as an inauspicious start in convincing colleagues and research sponsors about the value of his ideas. In a  recent piece in PartneringInsight, Dr. Langer shares lessons gleaned from his early-career experience.
Lab of the Month
The Lab of Dr. Cynthia St. Hilaire
This month we are highlighting the lab of Dr. Cynthia St. Hilaire, an Assistant Professor in the Division of Cardiology, at the University of Pittsburgh. Find out more about Dr. St. Hilaire and her lab at http://www.navbo.org/membership/members-labs/730-lab072018
Member News
Welcome to our New Members:
Christina Camell, Yale University
Chi Hsu, University of Rochester Medical Center
Xinyan Lu, University of Pittsburgh
Karin Simons, LUMC
Laura Wisniewski, University College London

If you have news to share with your colleagues, send it to membership@navbo.org.
 Recent Publications by NAVBO Members

The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model
Diabetic retinopathy (DR) is a major cause of vision impairment worldwide. We newly developed retinopathy mouse model (N-PRβ-KO) with conditional Pdgfrb gene deletion by Nestin promoter-driven Cre recombinase consistently reproduced through early non-proliferative to late proliferative DR pathologies.  Read more


Use of 4-phenylbutyrate to define therapeutic parameters for reducing intracerebral hemorrhage and myopathy in Col4a1 mutant mice
Disease Models and Mechanisms
Collagen type IV alpha 1 (COL4A1) and alpha 2 (COL4A2) form heterotrimers that constitute a major component of nearly all basement membranes. COL4A1 and COL4A2 mutations cause a multisystem disorder that includes variable cerebrovascular and skeletal muscle manifestations.  Read more


Diabetic Vascular Calcification Mediated by the Collagen Receptor Discoidin Domain Receptor 1 via the Phosphoinositide 3-Kinase/Akt/Runt-Related Transcription Factor 2 Signaling Axis
Arteriosclerosis, Thrombosis, and Vascular Biology
Objective - Vascular calcification is a common and severe complication in patients with atherosclerosis which is exacerbated by type 2 diabetes mellitus.  Read more


Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles
Science Advances
Dysfunctional endothelial cells contribute to the pathophysiology of many diseases, including vascular disease, stroke, hypertension, atherosclerosis, organ failure, diabetes, retinopathy, and cancer.  Read more

Industry News
Medicine explored in its social context
The American Association of Medical Colleges has announced the program for its annual meeting, " Learn Serve Lead 2018 ," scheduled for early November in Austin, Texas. The meeting features an installment of the Voices of Medicine and Society series, including sessions that closely examine the current practice of medicine from a patient-centered viewpoint. Diverse stakeholders-medical school deans, hospital CEOs, university and hospital administrators, faculty physicians, scientists, researchers, physician residents, and students-are invited to think about ways that academic medicine can address its shortcomings and solve challenges that reach beyond clinical care.
Heightened risk for hypertension in African Americans
Data from the ongoing, prospective Coronary Artery Risk Development in Young Adults (CARDIA) study, initiated in 1985, reveal that African Americans face up to a 2-fold higher risk for hypertension compared to whites, regardless of their blood pressure levels in young adulthood. The recent report from Thomas et al. in the Journal of the American Heart Association  noted that >75% of African Americans, male and female, are likely to develop hypertension (defined by the revised and controversial 2017 AHA standards ) by age 55, while <55% of white men and 40% of white women were at similar risk. Body weight and diet were implicated as contributing factors, irrespective of race or gender.
Advances in non-viral genome targeting to reprogram cell function 
Roth and colleagues at the multi-institutional Innovative Genomics Institute report in Nature  novel methods to efficiently modify genes in cells of the immune system. The findings raise the intriguing prospect of new approaches to treat diseases, including cancer, infections like H.I.V., and autoimmune conditions, where defined and limited genetic alterations may produce therapeutic benefit. Existing virus-dependent methods of engineering lymphocytes for immunotherapy are limited by technical and temporal obstacles; these may be overcome with the new technique, by which both CRISPR-based gene editing tools and new genetic material are introduced into target cells subjected to electrical stimuli.
Job Postings
Calendar of Events
July 14 - 15, 2018
Endothelial Cell Phenotypes in Health and Disease (GRS)
July 15 - 20, 2018
Endothelial Cell Phenotypes in Health and Disease (GRC)
July 16 - 17, 2018
9th Edition of International Conference on Preventive Medicine & Public Health
Sept. 9 - 13, 2018
11th World Congress of Microcirculation (WCM2018)
Oct. 14 - 18, 2018
Vascular Biology 2018
May 30 - June 1, 2019
Lymphatic Forum 2019
Oct. 27 - 31, 2019
Vascular Biology 2019
North American Vascular Biology Organization | bernadette@navbo.org | http://www.navbo.org
18501 Kingshill Road
Germantown, MD 20874-2211