May 12, 2016 
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In This Issue

NAVBO members receive discounts on registration to IVBM 2016

Travel Awards available for NAVBO members

Vasculata 2016
Uppsala University
University of Pennsylvania
August 15-18
Look inside the IVBM Virtual Conference Bag

Lymphatic Conference
in Chicago, IL
June 8-11, 2017

Vascular Biology 2017
Monterey, CA
October 15-19 
Corporate Partners
Corporate Members
Affiliated Journals
IVBM Supporters
Diamond Level
Welcome Reception Host

Gold Level

Meet the Professor Breakfasts Supported by
Event Partner
Silver Level
Academic Supporters

Bronze Level
Academic Supporters

NAVBO Elections for Council
2016 Ballot 
The following candidates are running for President-elect Cecilia Giachelli, University of Washington and Mark Kahn, University of Pennsylvania.

The following individuals have agreed to run for the two Councilor positions:
Rosemary J. Akhurst, University of California, San Francisco
Jason Fish, University of Toronto
Daniel M. Greif, Yale School of Medicine
Guillermo Oliver, Feinberg School of Medicine
A. Wayne Orr, LSU Health Science Center - Shreveport
Anand Ramamurthi, Cleveland Clinic
Linda H. Shapiro, University of Connecticut Medical School

Information about the candidates and the ballot can be found on our web site at:

Please note - only regular members can vote. 
Voting closes June 1 at 5pmEDT 
Lab of the Month
The Lab of Dr. Elisabetta Dejana
This month we are highlighting the lab of Dr. Elisabetta Dejana of the University of Milan in Italy and Uppsala University in Sweden. Find out more about Dr. Dejana's lab at
View all featured laboratories at
Lessons Learned
The NAVBO Education Committee has asked some junior faculty to share their experiences during the transition from trainee to first independent post.  We hope that their accounts of challenges confronted, dilemmas dissected, and lessons learned will help smooth your career path.  If you would like to share your own experiences, please send us reflections on your transition to Assistant Professor or whatever form of solo flight you undertook.  What helped you, what held you back, what was the "if only I had known" secret you can share.  Send your piece to [email protected].

See "Lessons Learned" pieces on our web site - 
Member News
Welcome our newest members:
Jason Butler, Weill Cornell Medical College
Hyun-Jung Choi, Yonsei University
Jennifer Esser, University of Freiburg
Piotr Kowalski, Koch Institute for Integrative Cancer Research / MIT
Patty J. Lee, Yale School of Medicine
Qian Zhou, University of Freiburg

If you have news to share with your colleagues, send it to [email protected].
Product Showcase
Submit your next manuscript to Thrombosis and Haemostasis - International Journal for Vascular Biology and Medicine!

The current average turnaround time from submission to first decision is only 23 days and the Impact Factor 2014 is 4.984.
The following Manuscript categories are accepted for review by the Editorial Board:

Original Articles: Coagulation and Fibrinolysis; Cellular Haemostasis and Platelets; Blood Cells, Inflammation and Infection; Endothelium and Angiogenesis; Cellular Signalling and Proteolysis; New Technologies, Diagnostic Tools and Drugs; Stroke, Systemic or Venous Thromboembolism; and Atherosclerosis and Ischaemic Disease 
Letters to the Editor (incl. Case Reports) 
T&H Images 
Trial Design Papers 
Review Articles (contact Editorial Office before Submission)
Here you can find the instructions and forms for your online submission:

Spotlight on Trainees
AAAS/SciLifeLab Prize for Young Scientists Now Seeking Entries
The American Association for the Advancement of Science, publisher of Science magazine, has partnered with SciLifeLab, a Swedish national center for molecular biosciences, to create the AAAS/SciLifeLab Prize for Young Scientists, in recognition of the dependence of global economic health upon a vibrant research community. Submissions are being accepted until August 1, 2016, for this year's competition, for which doctoral graduates may submit an essay based on their thesis work. Four winners, in different categories, will be selected for this international award. The grand prizewinner will receive $30,000; each of the three category winners will receive $10,000. The grand prize winning essay will be published in Science, and essays from the three category winners will be published online.
 Recent Publications by NAVBO Members

Smooth Muscle Enriched Long Non-Coding RNA (SMILR) Regulates Cell Proliferation
Background - Phenotypic switching of vascular smooth muscle cells (VSMCs) from a contractile to a synthetic state is implicated in diverse vascular pathologies including atherogenesis, plaque stabilisation, and neointimal hyperplasia. However, very little is known as to the role of long non coding RNA (lncRNA) during this process.  Read more

Endogenous Transmembrane TNF-Alpha Protects Against Premature Senescence in Endothelial Colony Forming Cells
Circulation Research
Rationale: Transmembrane TNF-a (tmTNF-a) is the prime ligand for TNFR2, which has been shown to mediate angiogenic and blood vessel repair activities in mice.  Read more 

Job Postings
Job Title
University of California, San Francisco
San Francisco, CA
Postdoctoral Positions
University of Massachusetts Medical School
Worcester, MA
Boston Children's Hospital - Harvard Medical School
Boston, MA
Clinical Assistant Professor
University of Florida
Gainesville, FL
Calendar of Events
May 25-28
ISTH 62nd Annual Scientific and Standardization Committee Meeting
July 17-22 Endothelial Cell Phenotypes in Health and Disease
Aug. 15-18 Vasculata 2016
Sept. 7-10 ISACB - 15th Biennial Meeting
Sept. 26-28 Perspectives in Vascular Biology
Oct. 30 - Nov. 3 19th International Vascular Biology Meeting
Nov. 13-16 American Society for Matrix Biology Biennial Meeting
Industry News
New role for macrophages in repair of brain vascular rupture
Fast repair of cerebrovascular ruptures that cause hemorrhagic stroke and brain microbleeds is vital for an effective therapeutic response. The dynamic cellular events involved in cerebrovascular repair remain unknown. Investigators at Southwest University in Beibei, China, using an experimental cerebrovascular rupture system in zebrafish, report that macrophages arriving at the lesion extend filopodia or lamellipodia to physically adhere to severed endothelial ends. These macrophages generate mechanical traction forces to pull the endothelial ends and facilitate their ligation, thus mediating the repair of the rupture.

Angiopoietin 2 expression in the cornea and its control of corneal neovascularization
British Journal of Ophthalmology
From the abstract: Researchers in Milan, Italy, report results of studies to define proangiogenic angiopoietin 2 (ANG2) expression and function in vascularized corneas. Corneal neovascularization (CNV) was induced in FVB mice by means of intrastromal suture placement. Corneas were whole-mounted, stained for CD31 and LYVE1 and lymphatic/blood vessels quantified. In humans and mice, ANG2 is expressed only in the epithelium, and modestly in the endothelium, of the avascular cornea. In vascularised corneas, ANG2 is expressed in the epithelium, endothelium and stroma. The authors suggest the existence of a mechanism regulating the onset of inflammation (and associated CNV) depending on injury severity.

Biomechanics of vascular mechanosensation and remodeling
Molecular Biology of the Cell

From the abstract: Endothelial cells lining the blood and lymphatic vessels experience fluid shear stress (FSS), a frictional force imposed by flowing blood. The endothelium continually senses the magnitude, pulsatility, and directionality of FSS. Sustained increases or decreases in FSS can induce vessel remodeling to maintain proper perfusion of tissue and pressure/flow relationships. This review, co-authored by NAVBO member Martin Schwartz, describes the mechanisms involved in vascular mechanotransduction mechanisms and their relevance to physiology and disease. 
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North American Vascular Biology Organization | [email protected] |
18501 Kingshill Road
Germantown, MD 20874-2211