Dear NIH Collaboratory family,

With this month’s newsletter, we pause to reflect on the NIH Collaboratory’s successes in 2018 and look forward to exciting opportunities to advance pragmatic research in 2019.

This year brought us much to celebrate. Highlights include:

  • Adding 6 new pragmatic clinical trials to our portfolio of Demonstration Projects. These research teams are using innovative methods to gather real-world evidence and disseminate knowledge and best practices as they conduct research embedded in clinical care.

  • Offering our first ePCT Training Workshop, where 27 clinical investigators from across the country convened to learn how to design and conduct embedded pragmatic clinical trials.



The coming year is ripe with opportunities. In 2019, we expect to: 

  • See several Demonstration Projects transition from their planning phase to their implementation phase.

  • Add a new cohort of Demonstration Projects through 2 new NIH funding opportunities for embedded pragmatic clinical trials that address pain management and the opioid crisis.

  • Hold a public workshop on design and analysis of embedded pragmatic clinical trials.

  • Expand our collection of tools and resources for researchers, healthcare system leaders, and others interested in pragmatic clinical research.

As the work of the NIH Collaboratory continues, we encourage you to take advantage of the ever-growing knowledge base of the Living Textbook. It truly is the gift that keeps on giving.

We wish you the happiest of holiday seasons, and we look forward to bringing renewed energy toward producing groundbreaking work in the new year.

Warm regards,

Kevin, Lesley, Adrian, and the NIH Collaboratory Coordinating Center