August 28, 2023

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

TERMINATION

MA32: CCTG led trial, “A Phase III Randomized Trial of Metformin versus Placebo on Recurrence and Survival in Early Stage Breast Cancer”, permanently closed/terminated.

FORM UPDATES

LUNG

NRG-LU005: An updated Frequently Asked Questions (FAQs) document, version date: August 23, 2023, has been added under the “Documents” tab to assist sites with common questions on eligibility and study processes (posted on CTSU).

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only Read More

2. BIOSPECIMEN BANK

Printing Biospecimen Transmittal PDFs from Rave

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

3. BRAIN

NRG-BN011: The central lab (NYU Langone) will be closed on Monday, September 4, 2023 in observance of Labor Day. Please plan tissue submissions accordingly.

4. BREAST

NSABP B-51/RTOG 1304: Call for submission of data and supporting documentation. Please see the memorandum, dated June 27, 2023, posted on CTSU for additional information.

NRG-BR008/HERO: Presentation slides from the recent Study Overview webinars are posted on CTSU.

5. GYNECOLOGIC

GOG-0210: Reminder: Biospecimens, biomarker data, clinical data, and epidemiologic data are available for request. Please visit the NRG Oncology website for more information on this important study with the overall goal of improving the outcome and/or quality of life for patients with endometrial cancer.

6. HEAD & NECK

NRG-HN008: Reminder: please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important.

7. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, NRG-CC005, and NRG/SWOG S1914. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday September 13, 2023.

DRUG SAFETY UPDATES

Drug Safety updates have been issued for the following studies:

Design and Management of Cancer Clinical Trials Course

Sylvester Comprehensive Cancer Center is pleased to invite cancer-focused trainees and early-career faculty from across the country to participate in their annual Design and Management of Cancer Clinical Trials Course. Developed for Sylvester K12 Calabresi Program scholars and modeled after the AACR-ASCO Methods in Clinical Cancer Research Workshop, this course teaches basic research concepts and principles that underlie the design and day-to-day conduct of cancer clinical trials.

The course is free and will be conducted completely online for 6 consecutive Fridays, from September 8 - October 13, 2023. Lectures, case studies, and panel discussions will take place from 10am to 1pm ET. To register, and for detailed agenda and speaker information, visit the course website. One-time registration allows access to all sessions. Recordings will be available upon request.

During the course, NRG Oncology Group Chair, Quynh-Thu Le, MD, with Alexia Lasonos, PhD, will be presenting the session, "Phase III and non-interventional trial design and statistics" on Friday, September 15 at 10am ET. We encourage our Early Career New Investigators to register for the course.

New Process for NRG NCORP Pilot Grant Applications – Informational Session

NRG NCORP committee leaders will host a pilot grant workshop during the NRG winter meeting, February 15 – 17, 2024. The goal of the workshop is to prepare investigators and researchers to develop committee aim-aligned NCORP pilot projects that would potentially lead to a larger NCORP concept.

•       An informational webinar to introduce the new process will be held on September 11, 2023. Registration is required (click here to register). The agenda is posted here.

For more information please view the NRG Oncology NCORP webpage.

NRG Mentorship Working Group Update

Are you a new CRA or CTN within NRG Oncology? Would you like a mentor to help guide you through your new role as a CRA or CTN? Are you an institution in need of more guidance after an audit? The Mentorship Working Group can provide you a mentor! You can apply for a mentor by going to the Introductory Materials page on the NRG website. You will find the Mentor Form to complete. The instructions on how to submit are located on the form. Hope to hear from you soon!

Labor Day Holiday Closures

Please refer to the memorandum posted on CTSU for information about NRG Oncology Operations offices, SDMCs, and Biospecimen and Serum Banks, and McKesson Research Services closures and shipping information for the upcoming Labor Day holiday on Monday, September 4, 2023.

NRG Oncology is pleased to report the scientific articles that appeared during the previous week. This publications report includes the links to these articles.

JOURNAL ARTICLES

Michalski JM, Winter KA, Prestidge BR, Sanda MG, Amin M, Bice WS, Gay HA, Ibbott GS, Crook JM, Catton CN, Raben A, Bosch W, Beyer DC, Frank SJ, Papagikos MA, Rosenthal SA, Barthold HJ, Roach M 3rd, Moughan J, Sandler HM. Effect of Brachytherapy With External Beam Radiation Therapy Versus Brachytherapy Alone for Intermediate-Risk Prostate Cancer: NRG Oncology RTOG 0232 Randomized Clinical Trial. J Clin Oncol. 2023 Aug 20;41(24):4035-4044. doi: 10.1200/JCO.22.01856. Epub 2023 Jun 14. PMID: 37315297. Read more.

Tchelebi LT, Winter KA, Abrams RA, Safran HP, Regine WF, McNulty S, Wu A, Du KL, Seaward SA, Bian SX, Aljumaily R, Shivnani A, Moore TD, Crocenzi TS, DiPetrillo TA, Kuykendal AR, Crane CH, Goodman KA. Analysis of radiation therapy quality assurance in NRG Oncology RTOG 0848. Int J Radiat Oncol Biol Phys. 2023 Aug 18:S0360-3016(23)07781-7. doi: 10.1016/j.ijrobp.2023.08.014. Epub ahead of print. PMID: 37598723. Read more.

Please note the following upcoming meetings and abstract submission deadlines

UPCOMING MEETINGS

American Society for Radiation Oncology (ASTRO); Oct 1-4, 2023; Chicago, IL

European Society of Gynaecological Oncology (ESGO); Sep 28-Oct 1, 2023; Istanbul, Turkey

International Gynecologic Cancer Society (IGCS); Nov 5-7, 2023; Seoul, South Korea

International Society for Quality-of-Life Research (ISOQOL); Oct 18-21, 2023; Calgary, AB, Canada

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Society of Clinical Oncology (ASCO) GI; Jan 18-20, 2024; San Francisco, CA; due to publications committee Aug 31, 2023; meeting submission deadline Sep 19, 2023, 11:59pm ET; LBA Oct 19, 2023, NOON ET

American Society of Clinical Oncology (ASCO) GU; Feb 16-18, 2023; San Francisco, CA; due to publications committee Sep 6, 2023; meeting submission deadline Sep 26, 2023, 11:59pm ET; LBA Oct 26, 2023, NOON ET

European Society for Medical Oncology (ESMO) Congress; Oct 20-24, 2023; Madrid, Spain; LBA Sep 14, 2023, 9pm CEST

San Antonio Breast Cancer Symposium (SABCS); Dec 5-9, 2023; LBA Sep 30, 2023, 11:59pm CT



Society for NeuroOncology (SNO); Nov 15-19, 2023; Vancouver, Canada; LBA Sep 4, 2023, 5pm ET