December 15, 2025

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Registration is OPEN for #NRG2026!

Registration is OPEN for the NRG 2026 Winter Meeting

Join us at the Hilton San Francisco Union Square for the NRG 2026 Winter Meeting. The meeting will be held in-person, January 22-24, 2026, with select virtual sessions being held January 12-16, and January 20, 2026. Register by January 2, 2026 to avoid the late registration fee!

NOTE: MDs and DOs who attend the meeting in-person and register for both the NRG Meeting and Winter Symposium will receive a bundle discount for a total fee of $325.00 USD. ($140.00 USD savings). Please use the discount code IPCOMBOMTGSYM.



More information | Agenda | Register

Winter 2026 Symposium – Theranostics: Precision Imaging Meets Targeted Therapy

Join us on in San Francisco, CA on Thursday, January 22, 2026 from 8am-12pm PT. The session will also be available virtually. This symposium will provide a comprehensive look at theranostics and radiopharmaceutical therapy. The program will begin with an introduction to the scientific foundations of radiopharmaceuticals, outlining how these agents differ from external beam radiation, and the practical considerations of imaging, dosimetry, and safe delivery. Participants will gain insight into the operational, regulatory, and infrastructural requirements needed to build a successful theranostics program within their institution.

Program Chair: Denise Fabian, MD and Co-Chairs: Charles Kunos, MD/PhD; Elise Kohn, MD

More information | Register

Announcing the #NRG2026 Investigator & Career Development Committee Educational Session!

This year’s program explores protocol development from every angle—early-career investigators shaping their first studies, experienced leaders refining best practices, NRG operations guiding feasibility, experts addressing health care access, and insights from a disease site committee leader. Additional information is included on the session flyer.

NRG Scientific Session - Friday, January 23, 3-4:30pm PT

Join us for the #NRG2026 Scientific Session featuring updates on antibody–drug conjugates and novel approaches in breast and ovarian cancer, followed by highlights from top recent NRG abstracts presented at national meetings. Details are included on the session flyer.

NCORP Bootcamp at #NRG2026

Join NRG Oncology NCORP leaders for the NCORP 2026 Bootcamp designed to increase understanding of the NRG Oncology NCORP Research Base and NCORP Community Sites:

• Dr. Lisa Kachnic will provide an overview of the functions and strategic role of an NCORP Research Base.
• Dr. Carolyn Muller, PI of the University of New Mexico NCORP, will share insights from the field describing the operations and impact of an NCORP community site.

A panel discussion will focus on developing and enrolling to NCORP trials, with perspectives from both.

All attendees are invited to participate in interactive breakout groups focused on:

• Patient advocate engagement - To help investigators strengthen their NCORP concepts by integrating patient advocate perspectives early in development ensuring trials are understandable, feasible, and meaningful to participants.
• CPC, HCA and PCOR committees – learn more about NCORP concept development, collaboration with NRG committees, and integration of health care access throughout NRG trial development.
• Developing a framework for Advanced Practice Providers within NRG Oncology.

The #NRG2026 Bootcamp is being held on Thursday, January 22, 2026. Additional information is included on the session flyer.

NRG Protocol Support Committee – Continuing Education Sessions

Please join the Protocol Support Committee for their upcoming Continuing Education sessions being held during #NRG2026 in San Francisco on Thursday, January 22, 2026. The Continuing Education Session for Nurse/CRAs on Thursday morning will be held virtually and in-person and is for both seasoned and new research staff. The monthly Discuss With Us session is being held in-person only and will cover topics including Onboarding & Retention, Biospecimen Collection & QOLs, and more! The Protocol Spotlight session on Thursday afternoon will be held in-person and virtually and will discuss the following studies – NRG-GU015, NRG-HN014, and NRG-CC014. Please refer to the posted agendas (login required) and flyers for more details about the PSC programing offered during #NRG2026. These sessions have been approved by the Virginia Nurses Association to award contact hours. The Virginia Nurses Association is accredited as an approver of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

AMENDMENTS

HEAD & NECK

NRG-HN014: Please see the CTSU website for “NRG-HN014 Study Memorandum Protocol Amendment 1 December 8, 2025_updated” which replaces the prior December 8 version of the study memorandum. The updated version removes the requirement for reconsent, which was included in error.

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only (posted on CTSU)

2. BIOSPECIMEN BANK

Update: Kit Shipments to Sites in Canada

The shipment of kits to sites in Canada has resumed. Sites no longer need to provide their FedEx account number when ordering kits, unless they request to have a kit shipped overnight. Please contact the NRG Biospecimen Bank in Columbus if you have any questions:

• Phone: 614-722-2865
• Email: BPCBank@nationwidechildrens.org

Printing Biospecimen Transmittal PDFs from Rave

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

3. BRAIN

NRG-BN011: The central lab, NYU Langone, will be closed on Thursday December 25, 2025 and Thursday January 1, 2026. Please plan tissue shipments accordingly.

4. CANCER PREVENTION & CONTROL

NRG-CC005/FORTE: Clinical research professionals can sign up for NRG Oncology Weekly Broadcasts to receive monthly FORTE Fridays updates directly to your inbox (click here).

NRG-CC013: If the protocol therapy cannot be administered according to schedule, the local PI should be involved in decisions regarding rescheduling. Treatment interruptions of radiation, cisplatin, and/or BMX-001 for non-medical reasons (holidays, vacations, weather, unexpected machine down time, etc) are at the treating investigator’s discretion and should follow local policy/practice. Interruptions should be documented in the treatment/research record and include the reason and duration.

5. GASTROINTESTINAL

NRG-GI008/CIRCULATE-North America: Natera Winter Holiday schedule (posted on CTSU)

NRG-GI008/CIRCULATE-North America: Memorandum, dated December 10, 2025, regarding availability of October 2025 webinar recording (posted on CTSU)

NRG-GI011: The following documents are available on CTSU:

• Study Memorandum dated November 14, 2025, regarding a clarification on prior radiation treatment Updated Training Slides, version date November 17, 2025
• Updated Training Slides, version date November 17, 2025

NRG-GI012: Canadian Informed Consent posted on CTSU.

6. GENITOURINARY

NRG-GU011: Please see Study Memorandum dated November 17, 2025 (posted on CTSU), regarding shipment timelines during the holidays. To avoid delays, submit shipment requests as soon as possible to support subject visits scheduled between November 10, 2025, and January 10, 2026.

7. GYNECOLOGIC

NRG-GY026: Accruing patients of all stages and all histologic subtypes of endometrial cancer.

NRG-GY031: Please note there is an error in the section 4.2 table and the Biospecimen Collection and Submission Manual. The Part I PK collection is to be done on Cycle 1, Day 1, and Cycle 1, Day 8. This will be updated with the next amendment.

NRG-GY037 requires blocks to be submitted, but the study team recognizes variations in site operating procedures to release blocks. Please refer to the Letter to Pathologists in the Biospecimen Collection and Submission Manual. If your site is experiencing any issues with this requirement, please contact the study team as we can work with sites on a case-by-case basis to ensure patients have an opportunity to participate in this trial.

8. HEAD & NECK

RTOG 1216: The Ferris Laboratory will not be accepting samples (fresh heparin and Streck blood tubes) from December 24, 2025 through January 1, 2026. The lab will begin receiving samples on January 2, 2026. Please plan your appointments accordingly to avoid any delays or compromised samples. Thank you for your attention and cooperation.

NRG-HN008 - Reminder: please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important.

NRG-HN014: The Spanish-translated consent form for Amendment 1 and CIRB approval of the form are available on the CTSU website.

9. SYMPTOM MANAGEMENT

NRG-CC011: Study Update memorandum, dated December 8, 2025 (posted on CTSU)

10. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on NRG-BN014, NRG-BR009, NRG-CC005, NRG-CC011, NRG-CC013, NRG-CC014, NRG-CC015, NRG-GI011, NRG-GI012, NRG-GU015, and NRG-HN014. Space is limited so register now and reserve your seat. The next webinar training is scheduled for December 10, 2025.

1. Winter Holiday Closure Information

Winter holiday closure information for the NRG Oncology Operations Offices, Statistics and Data Management Centers (SDMCs), Biospecimen Banks, and McKesson's Clinical Research Services is posted on the CTSU website (under LPO updates).

2. GYN Cancer Committee Requesting Proposals

The NRG Gynecologic Cancer Committee is requesting proposals for clinical trials in advance of the Winter Semiannual Meeting. Submit completed proposals by December 19, 2025. Read more

3. NRG Oncology Current Committee Leadership Openings

•  Vice Chair, Ancillary Projects Committee 

Applications DUE January 7, 2026 - Read more & How to Apply



•  Vice Chair, Protocol Operations Management Committee 

Applications DUE January 7, 2026 - Read more & How to Apply

 
4. NRG Oncology Research at San Antonio Breast Cancer Symposium

During the annual San Antonio Breast Cancer Symposium, Eleftherios Mamounas, MD, gave an oral presentation on the abstract, “A Multimodal-Multitask Deep Learning Model Trained in

NSABP B-42 and Validated in TAILORx for Late Distant Recurrence Risk in HR+ Early Breast Cancer.” The ECOG-ACRIN Cancer Research Group and Caris Life Sciences issued a joint press release announcing the first findings from their multi-year research collaboration to advance AI-powered multimodal tools for breast cancer recurrence risk stratification. Read the Press Release. View the list of presentations from researchers across NRG Oncology, NSABP Foundation, RTOG Foundation, and others here.

5. NEW NRG Oncology Podcast Episode with Dr. Bibbins-Domingo

The NRG Oncology Podcast just released a new episode this morning. The cohosts interview the Journal of the American Medical Association (JAMA) Editor in Chief, Dr. Kirsten Bibbins-Domingo to highlight the process behind the scenes for manuscript acceptance at JAMA and the JAMA Network. Tune in today – www.NRGOncology.org/Podcast

7. NRG Member Information Form

We are excited to introduce the NRG Member Information Data Collection Initiative that will allow us to create a comprehensive member database, enabling us to better understand and serve our members. Your information will be kept secure and confidential, ensuring that your privacy is always protected. All members are encouraged to complete the form or indicate that they wish to opt out of this data collection initiative. 

Scan the QR code below or click this link to access the form. 

Questions? Read more here

NRG Oncology is pleased to report the scientific articles that appeared during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

PUBLISHED ARTICLES

Gharzai LA, Morris E, Schipper MJ, Kidwell KM, Nguyen-Tân PF, Rosenthal DI, Gillison ML, Jordan RC, Garden AS, Koyfman SA, Caudell JJ, Blakaj DM, Dunlap NE, Krempl GA, Longo JM, Jones CU, Gensheimer MF, Galloway TJ, DeMora L, Le QT, Shah JL, Suresh K, Mierzwa M. Treatment Interruption and Outcomes in Head and Neck Cancer: A Secondary Analysis of 3 Randomized Clinical Trials. JAMA Otolaryngol Head Neck Surg. 2025 Dec 4:e254203. doi: 10.1001/jamaoto.2025.4203. Epub ahead of print. PMID: 41343184; PMCID: PMC12679426. Read more.

Please note the following upcoming meetings and abstract submission deadlines

UPCOMING MEETINGS

American Head & Neck Society (AHNS) Annual Meeting; Jul 18-22, 2026; Boston, MA

American Radium Society (ARS) Annual Meeting; Apr 30-May 3, 2026; Newport Beach, CA

American Society of Clinical Oncology (ASCO) GI; Jan 8-10, 2026; San Francisco, CA

American Society of Clinical Oncology (ASCO) GU; Feb 26-28, 2026; San Francisco, CA

Society for Clinical Trials (SCT); May 17-20, 2026; Phoenix, AZ

Society of Surgical Oncology (SSO) – Annual Meeting; Mar 5-7; Phoenix, AZ

Society of Surgical Oncology (SSO) – Advanced Cancer Therapies; Feb 14-16, 2026; Fort Lauderdale, FL

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Association for Cancer Research (AACR); Apr 17-22, 2026; San Diego, CA; LBA and Clinical Trials Jan 6, 2026, 11:59 pm ET

American College of Radiology (ACR); May 2-6, 2026; Washington, DC; Due to publications committee Jan 12, 2026; Submission deadline Jan 26, 2026, 11:59 pm ET

American Society of Breast Surgeons (ASBrS); Apr 29-May 3, 2026; Seattle, WA; LBA Jan 9, 2026, 12:00 am PT

American Society of Clinical Oncology (ASCO); May 29-Jun 2, 2026; Chicago, IL; Due to publications committee Jan 13, 2026; Submission deadline Jan 27, 2026, 11:59 pm ET; LBA Mar 9, 2026, 12:00 pm ET (placeholder required)

American Society of Colon and Rectal Surgeons (ASCRS); May 9-12, 2026; Tampa, FL; LBA and Clinical Trials Jan 28, 2026

American Society for Radiation Oncology (ASTRO); Boston, MA; Sep 27-30, 2026; Due to publications committee Feb 10, 2026; Submission deadline Feb 24, 2026; LBA Apr 20, 2026 (placeholder required)

European Society of Gynaecological Oncology (ESGO); Feb 26-Mar 1, 2026; Copenhagen, Denmark; LBA Jan 15, 2026

ESMO (European Society for Medical Oncology) Breast; May 6-8, 2026; Berlin, Germany; Due to publications committee Jan 13, 2026; Submission deadline Jan 27, 2026, 21:00 CST; LBA Mar 31, 2026, 21:00 CST (placeholder required)

European Society for Radiotherapy and Oncology (ESTRO); May 15-19, 2026; Stockholm, Sweden; LBA Apr 8, 2026

International Society for Quality-of-Life Research (ISOQOL); Oct 18-21, 2026; Prague, Czech Republic; Due to publications committee Mar 23, 2026; Submission deadline Apr 6, 2026

Miami Breast Cancer Conference; Mar 5-8, 2026; Miami, FL; Due to publications committee Dec 22, 2025; Submission deadline Jan 5, 2026, 5:00 pm ET