January 9, 2023

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

Registration is open for the NRG Oncology Winter 2023 Meeting to be held both in Orlando and virtually, January 26-28, 2023. Click here to register today!

REMINDER: CTN/CRA Workshop - Educational Sessions scheduled for Friday, January 27

Please be sure to sign up to attend the Clinical Trial Nurse (CTN)/CRA Workshop- Educational Session on Friday, January 27, 2023, from 7:30-11:30 am ET. The Protocol Support Committee (PSC) will offer the “Continuing Education Program” for in-person and virtual attendees. This session is for both seasoned and new research staff. Please refer to the agendas for PSC Programing offered at NRG2023. Agendas and slides for PSC sessions are currently posted on the NRG Oncology website (Login required).

See Flyer here

The PSC is thrilled to announce the PSC programing on January 26 and 27 have been approved by the Virginia Nurses Association to award a total of 10.25 contact hours. The Virginia Nurses Association is accredited as an approver of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

WINTER 2023 SYMPOSIUM

“Advances in Endometrial Cancer - Molecularly Driven Care” Thursday, Jan 26, 2023 - 8am – 12pm ET (See flyer here)

AMENDMENTS

GYNECOLOGIC

GOG-0225: Amendment 10; version date: November 30, 2022 (posted on NRG Oncology)

NRG-GY026: Amendment 4; version date: December 6, 2022 (posted on CTSU)

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Actively Recruiting MALE Patients only. Read More

2. BRAIN

NRG-BN011: The central lab (NYU Langone) will be closed on Monday, January 16, 2023 in observance of Martin Luther King Jr Day. Please plan tissue submissions accordingly. 

3. BREAST

NRG-BR007: Study Overview Webinars are being held on January 17, 2023, at 11am ET and 4pm ET. Please see the memorandum posted on CTSU for more information and for how to register by January 12.

4. CANCER PREVENTION & CONTROL

NRG-CC005/FORTE: The following information has been posted on CTSU:

·       Site Implementation Guide

·       Memorandum regarding Patient Video

·      Memorandum regarding Participant Travel Allowance

5. GYNECOLOGIC

Printing Biospecimen Transmittal PDFs on GYN Trials

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

GOG-0210: Biospecimens, biomarker data, clinical data, and epidemiologic data are available for request. Please visit the NRG Oncology website for more information on this important study with the overall goal of improving the outcome and/or quality of life for patients with endometrial cancer.

NRG-GY012 and NRG-GY023 – BLOOD PRESSURE CUFF SUPPLY IS VERY LIMITED - Please be advised that VWR has a very limited supply of blood pressure cuffs at present. Please check your supplies on site for any overlooked cuffs prior to ordering. Thank you for your cooperation.  

NRG-GY020: The research nurse on the protocol title page is retiring. For questions going forward, please contact Anna Brantley, RN at Anna.brantley@osumc.edu or 614-293-7582.

6. HEAD & NECK

NRG-HN008 Reminder: please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important.

7. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, NRG-CC005, and NRG/SWOG S1914. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday, January 11, 2023.

Request for PILOT Project Applications

Date Issued: December 1, 2022

Submission Due Date: February 17, 2023

NRG Oncology NCORP solicits PILOT projects addressing NRG NCORP Health Disparities Research (HDR) priorities. PILOT projects should generate preliminary data and address feasibility issues to inform the development of a future NCORP concept. The current focus of HDC is to move past simply documenting outcome differences to the development and testing of interventions to remedy them. Please see full details located on the NRG Health Disparities Committee webpage.

Reminder: AURORA Update

Sites are reminded AURORA will be live for site access on the morning of January 9, 2023. Users attempting to access OAOP will be redirected to AURORA for log-in. Please see the full announcement here.

Martin Luther King Holiday Closures

Please note the following NRG Oncology locations will be closed for the Martin Luther King holiday on Monday, January 16, 2023. Regular business hours resume on Tuesday, January 17. All other NRG Oncology locations not noted here will be open during regular business hours on Monday, January 16.

·       Philadelphia East Operations Center

·       Philadelphia West Operations Center

·       Pittsburgh Operations Center

·       Buffalo SDMC office

·       Philadelphia SDMC

·       Pittsburgh SDMC

·       Biospecimen Bank – San Francisco

·       Bio specimen Bank - Pittsburgh

·       Serum Bank- Baylor (no shipping restrictions)

McKesson’s Clinical Research Services will also be closed Monday, January 16, 2023. Regular business hours will resume on Tuesday, January 17, 2022. 

Reminder: Biospecimen Bank San Francisco Shipping Update

Due to an ongoing strike by some employees at the University of California, the NRG Oncology Biospecimen Bank San Francisco located at UCSF is requesting sites to use Fed Ex for all shipments to the bank until further notice. UPS deliveries to the San Francisco bank cannot be guaranteed during the strike. Please use Federal Express for specimen shipments or delay non-urgent shipments at this time. Please contact the lab at NRGBB@UCSF.EDU prior to resuming shipping by UPS.

NRG at ASCO GI 2023

NRG Oncology will have five featured presentations at the 2023 American Society of Clinical Oncology (ASCO) Gastrointestinal (GI) Cancers Symposium from January 19-21, 2023 in San Francisco, California. There will be two oral presentations, one by Dr. Laura Dawson on NRG-RTOG 1112, the phase III study of sorafenib versus stereotactic body radiation therapy followed by sorafenib in hepatocellular carcinoma, and the other by Dr. Thomas George on the long-term results from NRG-GI002, a phase II trial using total neoadjuvant therapy in locally advanced rectal cancer. Poster presentations are on the following trials: NRG-GI004 (the COMMIT Study), NRG-GI005 (the COBRA Study), and NRG-GI008 (the CIRCULATE-US Study). Download the flyer of all NRG presentations here. 

PUBLICATIONS REMINDERS

NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

JOURNAL ARTICLES

Caudell JJ, Torres-Saavedra PA, Rosenthal DI, Axelrod RS, Nguyen-Tan PF, Sherman EJ, Weber RS, Galvin JM, El-Naggar AK, Konski AA, Echevarria MI, Dunlap NE, Shenouda G, Singh AK, Beitler JJ, Garsa A, Bonner JA, Garden AS, Algan O, Harris J, Le QT. Long-term update of NRG/RTOG 0522: a randomized phase III trial of concurrent radiation and cisplatin with or without cetuximab in locoregionally advanced head and neck cancer. Int J Radiat Oncol Biol Phys. 2022 Dec 19:S0360-3016(22)03636-7. doi: 10.1016/j.ijrobp.2022.12.015. Epub ahead of print. PMID: 36549347. Read more

Craig T, Xiao Y, McNulty S, Dawson LA. Insights from IGRT Credentialing for the NRG Oncology RTOG 1112 Liver SBRT Trial. Pract Radiat Oncol. 2022 Dec 26:S1879-8500(22)00385-X. doi: 10.1016/j.prro.2022.11.013. Epub ahead of print. PMID: 36581199. Read more

Lukka HR, Deshmukh S, Bruner DW, Bahary JP, Lawton CAF, Efstathiou JA, Kudchadker RJ, Ponsky LE, Seaward SA, Dayes IS, Gopaul DD, Michalski JM, Delouya G, Kaplan ID, Horwitz EM, Roach M 3rd, Feng FY, Pugh SL, Sandler HM, Kachnic LA. Five-year patient reported outcomes in NRG Oncology RTOG 0938, evaluating two ultrahypofractionated regimens for prostate cancer. Int J Radiat Oncol Biol Phys. 2022 Dec 30:S0360-3016(22)03671-9. doi: 10.1016/j.ijrobp.2022.12.022. Epub ahead of print. PMID: 36592721. Read more

McDonald AM, DeMora L, Yang ES, Hoyle JM, Lenzie A, Williams GR, Michalski JM, Yee D, Bahary JP, Den RB, Roach M 3rd, Dess R, Mishra MV, Valicenti RK, Lau HY, Marcrom SR, Souhami L, Mendez LC, Chen Y, Doncals DE, Pugh SL, Feng FY, Sandler HM. Body composition and mortality in men receiving prostate radiotherapy: A pooled analysis of NRG/RTOG 9406 and NRG/RTOG 0126. Cancer. 2022 Dec 29. doi: 10.1002/cncr.34596. Epub ahead of print. PMID: 36579470. Read more

Nguyen PL, Huang HR, Spratt DE, Davicioni E, Sandler HM, Shipley WU, Efstathiou JA, Simko JP, Pollack A, Dicker AP, Roach M 3rd, Rosenthal SA, Zeitzer KL, Mendez LC, Hartford AC, Hall WA, Desai AB, Rabinovitch RA, Peters CA, Rodgers JP, Tran P, Feng FY. Analysis of a biopsy-based genomic classifier in high-risk prostate cancer: Meta-analysis of the NRG Oncology/RTOG 9202, 9413, and 9902 phase III randomized trials. Int J Radiat Oncol Biol Phys. 2022 Dec 31:S0360-3016(22)03688-4. doi: 10.1016/j.ijrobp.2022.12.035. Epub ahead of print. PMID: 36596347. Read more

Please note the following upcoming meeting and abstract submission deadline dates

UPCOMING MEETINGS

American Society of Clinical Oncology (ASCO) GI; Jan 19-21, 2023; San Francisco, CA

American Society of Clinical Oncology (ASCO) GU; Feb 16-18, 2023; San Francisco, CA

ESMO Gynaecological Cancers Annual Congress 2023; Feb 23-24, 2023; Barcelona, Spain

Society of Gynecologic Oncology (SGO); Mar 25-28, 2023; Tampa, FL

Society of Surgical Oncology (SSO) Feb 18-20, 2023; San Diego, CA Advanced Cancer Therapies (ACT)

Society of Surgical Oncology (SSO); March 22-25, 2023; Boston, MA

St. Gallen Breast Cancer Conference (SG-BCC); Mar 15-18, 2023; Vienna, Austria

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Association for Cancer Research (AACR); Apr 14-19, 2023; Orlando, FL; LBA Jan 12, 2023

American College of Radiology (ACR); May 6-10, 2023; Washington DC; meeting submission deadline Jan 13, 2023

American Society of Clinical Oncology (ASCO); Jun 2-6, 2023; Chicago, IL; due to publications committee Jan 24, 2023; meeting submission deadline Feb 14, 2023 1159 pm EST; LBA Mar 16, 2023 Noon (EST)

American Society for Radiation Oncology (ASTRO); Oct 1-4, 2023; Chicago, IL; due to publications committee Feb 9, 2023; meeting submission deadline Feb 13, 2023 1159 PT

European Society for Radiotherapy and Oncology (ESTRO); May 12-16, 2023; Vienna, Austria; LBA Jan 18, 2023, 1159 pm CET



ESMO Breast Cancer Annual Congress; May 11-13, 2023; Berlin, Germany; due to publications committee Feb 7, 2023; meeting submission deadline Feb 21, 2023 TiP, LBA placeholder 9 pm CET; LBA Apr 12, 2023 9pm CntEurSummrTime