July 10, 2023

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

NRG Oncology Summer Meeting Registration is Open!

Join us in celebrating our 10^th anniversary at our Summer Meeting in Philadelphia from Thursday, July 20, 2023 - Saturday, July 22, 2023. Sessions will be held in-person and available via streaming unless noted. Additionally, there will be virtual-only sessions on Monday and Tuesday, July 17-18, 2023. Click here to Register Today

Hotel Reservations can still be made by contacting the Philadelphia Marriott directly (The NRG group rate is no longer available).

Summer Symposium - Rare Tumors: Ideas for Implementation of Novel Concepts.

Be sure to register for this informative event happening Thursday, July 20, 2023. 8am – 12pm ET. Presentations will focus on the design, implementation strategies, and progress in clinical trials involving rare tumors. The information presented will span novel clinical trial design with incorporation of novel statistical design and molecular profiling.

See flyer for more information

Reminder: NRG Protocol Support Committee – Educational Sessions

Please be sure to sign up to attend the PSC Nurse/CRA Educational Sessions being held during the NRG Oncology Summer Meeting. The Protocol Support Committee (PSC) will offer Continuing Education sessions on Thursday, July 20, and a Protocol Spotlight session (featuring presentations for NRG-BR009, GU010, and GY025) on Friday, July 21. These sessions are for both seasoned and new research staff. Please refer to the posted flyers and agendas for more details about the PSC programing offered at #NRG2023. Agendas and slides for PSC sessions are currently posted on the NRG Oncology website (Login required).

The PSC is thrilled to announce that the PSC sessions have been approved by the Virginia Nurses Association to award a total of 9.25 contact hours. The Virginia Nurses Association is accredited as an approver of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.

Last Chance! Social Media Ambassadors wanted for #NRG2023

Apply now to be a #NRG2023 Social Media Ambassador for the NRG Oncology Summer Meeting being held July 20-22, 2023, in Philadelphia! This is the 10^th anniversary celebration of NRG Oncology, so what better way to raise your profile than to be posting on your Twitter and/or Instagram accounts about all things #NRG2023? If interested, please send an e-mail (& please include your Twitter handle) to: communications@nrgoncology.org or

send us a DM on Twitter by July 10th.

Join us at the Barnes

NRG Oncology will host our 10th anniversary at the Barnes Foundation on Friday, July 21st from 6-8 PM. Transportation will be provided.

AMENDMENTS

BRAIN

NRG-BN011: Amendment 2, version date May 9, 2023 (posted to CTSU)

GYNECOLOGIC 

EAY191-N4: Amendment 2; version date: June 14, 2023. Documents and additional forms are posted on CTSU.

FORM UPDATES

BRAIN

NRG-BN011: The Blank Rave Forms document, Eligibility Checklist, Eligibility Checklist 2 and the P4 Form have been updated. The updated version is posted to CTSU. Please begin using these new Forms immediately.

TEMPORARY CLOSURE

GASTROINTESTINAL

NRG-GI005/COBRA: Temporarily suspended as of July 5, 2023, to accrual until further notice for an interim analysis determination. Additional information for patients will be forthcoming shortly. Please refer to the memorandum, dated July 5, 2023, posted on the CTSU website for additional information.

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only Read More

2. BREAST

NRG-BR007/DEBRA: Protocol Overview webinar recording available on the NRG Oncology website under the Documents & Materials tab for BR007.

3. GASTROINTESTINAL

NRG-GI002: Call for submission of data and supporting documentation. Please refer to the memorandum, dated July 10, 2023, posted on the CTSU website for additional information.

4. GENITOURINARY

NRG-GU009: Patient Video was approved by CIRB and posted to NRG website. CIRB approval posted to CTSU.

5. GYNECOLOGIC

GOG-0210: Reminder: Biospecimens, biomarker data, clinical data, and epidemiologic data are available for request. Please visit the NRG Oncology website for more information on this important study with the overall goal of improving the outcome and/or quality of life for patients with endometrial cancer.

NRG-GY012 and NRG-GY023 – Reminder: BLOOD PRESSURE CUFF SUPPLY IS VERY LIMITED - Please be advised that VWR has a very limited supply of blood pressure cuffs at present. Please check your supplies on site for any overlooked cuffs prior to ordering. Thank you for your cooperation. 

Printing Biospecimen Transmittal PDFs on GYN Trials

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

6. HEAD & NECK

NRG-HN001: An updated patient brochure and CIRB approval of the document are available on CTSU. A patient study web page is available on NRG Oncology.

NRG-HN008

Reminder: please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important. 

7. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, NRG-CC005, and NRG/SWOG S1914. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday July 12, 2023.

DRUG SAFETY UPDATES

Drug Safety updates have been issued for the following studies:

NRG Oncology Seeks to Fill the Position of Vice-Chair, NRG Oncology NCORP Health Disparities Research Committee

Application Deadline: July 28, 2023

We are seeking nominations for the position of Vice-Chair of the NRG NCORP Health Disparities Research (HDR) committee. The successful candidate will work closely with the chair, Dr. Jennifer Wenzel and provide support to lead the HDR committee. The overarching goal of NRG HDR is to understand and address health disparities in an effort to reduce the unequal burden of cancer in the United States. Candidates for this position should have a track record of funding and/or publications in successful methods to improve access to clinical trials in historically underserved populations. The candidate should demonstrate a passion to elevate and nurture cancer equity, ensuring that NRG Oncology trials prioritize health and cancer outcomes for all patients, families, and communities. Further, the candidates should have documented achievements in mentorship and a willingness to provide timely consultation to members and liaisons of NRG committees as concepts and protocols are being developed. Read more

REGISTER TODAY! The NRG Oncology Brain Metastasis Trial Webinar: Portfolio Review

NRG Oncology Brain Tumor Committee will be hosting a webinar on brain metastasis trials in the NRG Oncology portfolio. This session will be lead by NRG Brain Tumor Committee Chair, Dr. Minesh Mehta, and will feature presentations on NRG-BN012, CCTG CE.7, NRG-CC009, and NRG-BN009. The webinar will be held on August 4, 2023 from 1-2pm ET. Download the webinar flyer here.  Register here.

NRG Oncology is pleased to report the scientific articles that appeared during the previous week. This publications report includes the link to these articles.

JOURNAL ARTICLES

Konski A, Deshmukh S, Klopp AH, Yeung AR, Westin SN, Thompson JS, Doncals DE, Cantuaria GHC, D'Souza DP, Chang A, Kundapur V, Mohan DS, Haas ML, Kim YB, Ferguson CL, Pugh SL, Kachnic LA, Bruner DW. Quality-adjusted survival in women with gynecologic malignancies receiving IMRT after surgery: A patient reported outcome study of NRG Oncology's RTOG 1203. Gynecol Oncol. 2023 Jun 30;175:176-181. doi: 10.1016/j.ygyno.2023.05.074. Epub ahead of print. PMID: 37393743. Read more.

Wen J, Wang MC, Hu C. Simultaneous hypothesis testing for multiple competing risks in comparative clinical trials. Stat Med. 2023 Jun 30;42(14):2394-2408. doi: 10.1002/sim.9728. Epub 2023 Apr 10. PMID: 37035880; PMCID: PMC10315219. Read more.

Caudell JJ, Torres-Saavedra PA, Rosenthal DI, Axelrod RS, Nguyen-Tan PF, Sherman EJ, Weber RS, Galvin JM, El-Naggar AK, Konski AA, Echevarria MI, Dunlap NE, Shenouda G, Singh AK, Beitler JJ, Garsa A, Bonner JA, Garden AS, Algan O, Harris J, Le QT. Long-Term Update of NRG/RTOG 0522: A Randomized Phase 3 Trial of Concurrent Radiation and Cisplatin With or Without Cetuximab in Locoregionally Advanced Head and Neck Cancer. Int J Radiat Oncol Biol Phys. 2023 Jul 1;116(3):533-543. doi: 10.1016/j.ijrobp.2022.12.015. Epub 2022 Dec 19. PMID: 36549347; PMCID: PMC10247515. Read more.

Nguyen PL, Huang HR, Spratt DE, Davicioni E, Sandler HM, Shipley WU, Efstathiou JA, Simko JP, Pollack A, Dicker AP, Roach M, Rosenthal SA, Zeitzer KL, Mendez LC, Hartford AC, Hall WA, Desai AB, Rabinovitch RA, Peters CA, Rodgers JP, Tran P, Feng FY. Analysis of a Biopsy-Based Genomic Classifier in High-Risk Prostate Cancer: Meta-Analysis of the NRG Oncology/Radiation Therapy Oncology Group 9202, 9413, and 9902 Phase 3 Randomized Trials. Int J Radiat Oncol Biol Phys. 2023 Jul 1;116(3):521-529. doi: 10.1016/j.ijrobp.2022.12.035. Epub 2022 Dec 31. PMID: 36596347; PMCID: PMC10281690. Read more.

Please note the following upcoming meetings and abstract submission deadlines

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Society for Radiation Oncology (ASTRO); Oct 1-4, 2023; Chicago, IL; LBA Jul 12, 2023

European Society of Gynaecological Oncology (ESGO); Sep 28-Oct 1, 2023; Istanbul, Turkey; LBA Aug 7, 2023

European Society for Medical Oncology (ESMO) Congress; Oct 20-24, 2023; Madrid, Spain; LBA Sep 14, 2023, 9pm CEST

International Gynecologic Cancer Society (IGCS); Nov 5-7, 2023; Seoul, South Korea; Abstract & Film; TiP LBA, Aug 21, 2023

International Society for Quality-of-Life Research (ISOQOL); Oct 18-21, 2023; Calgary, AB Canada; LBA Jul 7, 2023

San Antonio Breast Cancer Symposium (SABCS); Dec 5-9, 2023; meeting submission deadline Jul 10, 2023; LBA Sep 30, 2023, 11:59 PM CT.

Society for NeuroOncology (SNO); Nov 15-19, 2023; Vancouver, Canada; LBA Sep 4, 2023, 5:00 PM EDT.