March 13, 2023

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

ACTIVATIONS

BREAST

EAY191- N2: ComboMATCH - Activated March 6, 2023; version date: February 2, 2023 (posted on CTSU)

GYNECOLOGIC

EAY191- N4: ComboMATCH - Activated March 6, 2023; version date: February 2, 2023 (posted on CTSU)

REACTIVATION

HEAD & NECK

NRG-HN008: Reopening to Accrual and Amendment 3; version date: February 14, 2023 (posted on CTSU) and Study Memorandum dated March 13, 2023 (posted on NRG Oncology) 

AMENDMENTS

BRAIN

NRG-BN007: Amendment 3; version date: January 17, 2023 (posted on CTSU)

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Actively Recruiting MALE Patients only Read More

2. BRAIN

NRG-BN012: The Spanish-translated consent form and CIRB approval of the form are available on CTSU.

3. GYNECOLOGIC

Printing Biospecimen Transmittal PDFs on GYN Trials

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

GOG-0210: Reminder: Biospecimens, biomarker data, clinical data, and epidemiologic data are available for request. Please visit the NRG Oncology website for more information on this important study with the overall goal of improving the outcome and/or quality of life for patients with endometrial cancer.

NRG-GY012 and NRG-GY023 – Reminder: BLOOD PRESSURE CUFF SUPPLY IS VERY LIMITED - Please be advised that VWR has a very limited supply of blood pressure cuffs at present. Please check your supplies on site for any overlooked cuffs prior to ordering. Thank you for your cooperation. 

NRG-GY028: Biospecimen Collection and Submission Manual; version date March 13, 2023, and Required Forms and Materials; version date March 8, 2023, have been updated on the NRG Oncology study webpage

4. HEAD & NECK

NRG-HN008: Reminder - Please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important.

5. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, NRG-CC005, and NRG/SWOG S1914. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday, April 5, 2023.

DRUG SAFETY UPDATES

Drug Safety updates have been issued for the following studies:

1. Reminder About CTSU Website Access

Access to the CTSU Website is managed through the Cancer Therapy Evaluation Program - Identity and Access Management (CTEP-IAM) registration system and ID.me (which incorporates Identity Proofing (IP) and Multi-Factor Authentication (MFA) into the registration process). All users must have an active CTEP-IAM account linked with an ID.me account to access the CTSU website. If you have not completed this process, you have until July 1, 2023, to register with ID.me. Please remember this is a Federal requirement to access U.S. government IT applications according NIST SP 800-63-3 Digital Identity Guidelines.

For more information please visit:

• CTEP website for detailed instructions, FAQs, live webinar schedule & registrations, and other helpful information
• ID.me support for assistance with your ID.me account
• Ctephelpdesk@nih.gov for help with the CTEP-IAM and ID.me process, questions about the timeline, and solutions for users unable to register with ID.me.

2. REMINDER! Expansion of Safety-Lead in Sites for NRG Phase I Committee

The NRG Phase I Subcommittee is looking to expand the number of sites who can participate on the safety lead-in component of studies. Key considerations for being a safety lead-in site are:

·       -the ability to enter patient safety data in real-time

·       -site physician member or physician delegate must participate on safety calls (currently Friday afternoons at 3:30PM ET). Click here for application and more information.

Responses requested by March 20, 2023.

3. Annual Call for NRG Oncology Administrative Committee Member Applications

Are you interested in serving on an NRG Oncology administrative committee? NRG Oncology depends on its members to assist with carrying out critical tasks to ensure the engagement of research personnel in high quality research and to support the timely dissemination of the group's research results and important programmatic information. If you are interested in serving on one of the NRG Oncology administrative committees or if you are a member who had previously served on a committee and would like to re-engage, please consider applying by following the instructions in the application and submitting a complete application. Application Link

All applications must be submitted by midnight April 4, 2023.

Current committee members do not need to reapply.

The next call for administrative committee applications will occur in the Spring 2024. The next call for NRG Oncology cancer disease site committees, non-disease site committees, and scientific core committees will occur in Fall 2023.

4. RFAs for the NRG Early Career & New Investigators (ECNI) Committee AND for the NRG ECNI Mentored Fellowship

The NRG Oncology Early Career & New Investigators Committee is seeking applications for a one-year Mentored Fellowship. The purpose of Early Career & New Investigators Committee Mentored Fellowship is to identify Early Career & New Investigators who wish to develop their research ideas within NRG Oncology through close mentorship by the NRG Oncology Early Career Disease Site Liaisons and the NRG Oncology Disease Site Chairs. Read more

All applications must be submitted by 5 PM ET on Monday, March 31, 2023

The NRG Oncology Early Career & New Investigators (ECNI) Committee is seeking applications for a two-year Committee membership. The purpose of Early Career & New Investigators Committee membership is to identify Early Career & New Investigators who wish to become more engaged with NRG Oncology, learn more about the NRG Oncology clinical trial development process, and deepen their involvement in various research opportunities within NRG Oncology. It is anticipated that Committee members might pursue the NRG Oncology Mentored Fellowship at the time of future requests for applications of that award. Read more

All applications must be submitted by 5 PM ET on Monday, March 31, 2023.

Current committee members need to reapply.

5. Request for NCORP pilot project applications

Date Issued: February 17, 2023

Submission Due Date: April 21, 2023

NRG Oncology NCORP solicits PILOT projects addressing NRG NCORP Cancer Care Delivery Research (CCDR), Cancer Prevention and Control (CPC) Research and Health Disparities Research (HDR) priorities. PILOT projects should generate preliminary data and address feasibility issues to inform the development of a future NCORP concept. Refer to the links below for further details.

Cancer Care Delivery Research (CCDR)

Cancer Prevention and Control (CPC)

Health Disparities Research (HDR)

6. Call for Applications for 2 NRG Committee Leadership Positions

Vice Chair, NRG Immunotherapy Subcommittee

Application Deadline: March 15, 2023

We are seeking nominations for the position of Vice-Chair, NRG Immunotherapy Subcommittee. This subcommittee within NRG sits within the NRG Medical Oncology Committee, a Scientific Core Committee, and aides in cross-group collaboration and engagement around immune-therapy agents and serving as subject matter experts on related topics. Subcommittee members will help liaise within the disease-specific committees in supporting developing concepts and protocols where immune-oncology agents may be appropriate for the patient cohorts in NRG’s portfolio. Click here for more information.

Chair, NRG Publications Committee

Application Deadline: March 15, 2023

We are seeking nominations for the position of Chair, NRG Oncology Publications Committee. The Publication Committee within NRG promotes and facilitates the publication of studies to ensure NRG Oncology results are published in a timely manner, assures authorship lines are appropriate, reviews the science of abstracts and papers, assures timely reporting by assigning or reassigning responsibility, monitoring compliance with the Publication Policy, and proposes recommendations to update the Publications Policy as necessary. The Publications Committee may be required to consider and adjudicate appeals and/or disputes related to publications and may be required to issue recommendations to the Group Chairs for final decision. Click here for more information.

NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

JOURNAL ARTICLES

Subramaniam RM, DeMora L, Yao M, Yom SS, Gillison M, Caudell JJ, Waldron J, Xia P, Chung CH, Truong MT, Echevarria M, Chan JW, Geiger JL, Mell L, Seaward S, Thorstad WL, Beitler JJ, Sultanem K, Blakaj D, Le QT. 18F-FDG PET/CT Prediction of Treatment Outcomes in Human Papillomavirus-Positive, Locally Advanced Oropharyngeal Cancer Patients Receiving Deintensified Therapy: Results from NRG-HN002. J Nucl Med. 2023 Mar;64(3):362-367. doi: 10.2967/jnumed.122.264424. Epub 2022 Sep 2. PMID: 36215572. Read more

Please note the following upcoming meeting and abstract submission deadlines

UPCOMING MEETINGS

American Association for Cancer Research (AACR); Apr 14-19, 2023; Orlando, FL

American Association for Thoracic Surgery (AATS); May 6-9, 2023; Los Angeles, CA

American College of Radiology (ACR); May 6-10, 2023; Washington DC

Society of Gynecologic Oncology (SGO); Mar 25-28, 2023; Tampa, FL

Society of Surgical Oncology (SSO); Mar 22-25, 2023; Boston, MA

St. Gallen Breast Cancer Conference (SG-BCC); Mar 15-18, 2023; Vienna, Austria

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Association of Physicists in Medicine (AAPM); Jul 23-27, 2023; Houston, TX; meeting submission deadline Feb 28, 2023, 8pm ET

American Society of Clinical Oncology (ASCO); Jun 2-6, 2023; Chicago, IL; LBA Mar 16, 2023, 12 Noon ET

American Society for Radiation Oncology (ASTRO); Oct 1-4, 2023; Chicago, IL; LBA Jul 12, 2023

ESMO World Congress on Gastrointestinal Cancer; Jun 28-Jul 1, 2023; Barcelona, Spain; LBA Jun 15, 2023

European Society of Gynaecological Oncology (ESGO); Sep 28-Oct 1, 2023; Istanbul, Turkey; due to publications committee Apr 24, 2023; meeting submission deadline May 8, 2023; LBA Aug 7, 2023

European Society for Medical Oncology (ESMO) Congress; Oct 20-24, 2023; Madrid, Spain; due to publications committee Apr 26, 2023; meeting submission deadline May 10, 2023, 9pm CntEurSummerTime (CEST); LBA Sep 14, 2023, 9pm CEST

International Gynecologic Cancer Society (IGCS); Nov 5-7, 2023; Seoul, South Korea; due to publications committee Apr 24, 2023; meeting submission deadline May 8, 2023, Abstract & Film; TiP LBA, Aug 21, 2023

International Society for Quality-of-Life Research (ISOQOL); Oct 18-21, 2023; Calgary, AB Canada; due to publications committee Mar 20, 2023; meeting submission deadline Apr 3, 2023; LBA Jul 7, 2023

Radiological Society of North America (RSNA); Nov 27-Dec 1, 2023; Chicago, IL; due to publications committee Apr 19, 2023; meeting submission deadline; May 3, 2023, 12 Noon CT

Western Association of Gynecologic Oncologists (WAGO); Jun 14-17, 2023; Monterey, CA; due to publications committee Mar 20, 2023; meeting submission deadline Apr 2, 2023, Sunday 11:59pm PT