March 3, 2025

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

NRG Oncology GYN Cancer Committee is Requesting Proposals

Submit your proposals in advance of the April 11, 2025 Interim Meeting. Read more

CLOSURES

GYNECOLOGIC

NRG-CC008/SOROCk: Temporary accrual hold for the 42-50 age block of the BSO arm until the 42-50 BLS age block enrolls 189 patients. The BLS arm for the 42-50 age block and the 35 to <42 BLS and BSO age blocks will remain open for accrual. This age blocking is specified in the protocol to ensure equal distributions of patients because this is a non-randomized study. Please see protocol Section 14.5 for a description of the age blocking. (posted on CTSU)

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only Read More

2. BIOSPECIMEN BANKS

Printing Biospecimen Transmittal PDFs from Rave

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

3. BREAST

NRG-BR008/HERO: Study webinars are being held via Microsoft Teams on March 24th at 3pm ET and March 26th at 11am ET. Please see the memorandum, dated February 24, 2025, (posted on CTSU) for details and how to register for one of the sessions. Please note: Google Chrome is the preferred browser to register for the webinars.

NRG-BR008/HERO: March 2025 eBlast (posted on CTSU)

4. CANCER PREVENTION & CONTROL

NRG-CC010: The study is open to NRG sites in Japan and South Korea. The optional biospecimen collection does not apply to sites participating in these countries.

5. GYNECOLOGIC

NRG-GY026: Please note, the post-chemo cfDNA Whole Blood (WB03) should only be collected if the Pre-Treatment cfDNA Whole Blood (WB01) was collected.

NRG-GY031: Please note, there is an error in the section 4.2 table and the Biospecimen Collection and Submission Manual. The Part I PK collection is to be done on Cycle 1, Day 1, and Cycle 1, Day 8. This will be updated with the next amendment.

6. HEAD & NECK

NRG-HN008 - Reminder: please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important. 

7. LUNG

S1914: A memorandum has been posted to CTSU regarding termination of QOL instructing sites to discontinue administration as of February 1, 2025. All delinquent QOL data up until this date is to be entered into Rave for S1914-E-01. Please review all cases at your site for completion. 

8. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on NRG-BN014, NRG-BR009, NRG-CC003, NRG-CC005, NRG-CC011, NRG-CC013, NRG-HN001, NRG-HN002, and NRG-HN014. Space is limited so register now and reserve your seat. The next webinar training is scheduled for March 12, 2025.

Drug Safety and Investigator’s Brochure (IB*) updates have been issued for the following studies:

*The current version of the Investigator Brochure Documents for Division of Cancer Treatment and Diagnosis (DCTD), National Cancer Institute (NCI)-sponsored trials are available for access via the Cancer Therapy Evaluation Program (CTEP) Agent Inventory Management System (AURORA) application. Log-in using your Identity and Access Management (IAM) or ID.me credentials and provide the requested information to access the document.

Every site principal investigator is responsible for reviewing this document. The Investigator Brochure is for use by the site principal investigator and any study personnel under his/her supervision who need to know the contents for the conduct of a clinical trial, including Institutional Review Board(s) or Independent Ethics Committee(s).

1. NRG Oncology GYN Cancer Committee is Requesting Proposals

Submit your proposals in advance of the April 11, 2025 Interim Meeting. Read more

2. NRG Mentorship Working Group Update

Are you a new CRA or CTN within NRG Oncology? Would you like a mentor to help guide you through your new role as a CRA or CTN? Are you an institution in need of more guidance after an audit? The Mentorship Working Group can provide you with a mentor! You can apply for a mentor by going to the Introductory Materials page on the NRG website. You will find the Mentor Form to complete. The instructions on how to submit are located on the form. Hope to hear from you soon!

3. NRG Member Information Form

We are excited to introduce the NRG Member Information Data Collection Initiative that will allow us to create a comprehensive member database, enabling us to better understand and serve our members. Your information will be kept secure and confidential, ensuring that your privacy is always protected. All members are encouraged to complete the form or indicate that they wish to opt out of this data collection initiative. 

Scan the QR code below or click this link to access the form. 

Questions? Read more here

NRG Oncology is pleased to report the following abstract accepted for presentation at the 2025 meeting of the Particle Therapy Co-Operative Group (PTCOG).

ACCEPTED ABSTRACTS

Qian D, Chen H, Liao Z, Bradley JD, Presley J, Villanueva L, Chun SG, Kotecha R, Samson P, Feigenberg SJ, Wu A, Stokes WA, Rana Z, Daugherty EC, Willers H, Mohammed N, Mohindra P, Jaramillo S, Lyness JA, Xiao Y. Proton versus photon radiation dose to immune cells and organs-at-risk in LA-NSCLS: Dosimetric analysis of RTOG 1308, a phase III RCT. PTCOG (Particle Therapy Co-Operative Group). 6/2/2025. 193 

PUBLISHED ARTICLES 

Bandos H, Torres-Saavedra PA, Culakova E, Gunn HJ, Lee MK, Duan F, Cecchini RS, Unger JM, Dueck AC, Steingrimsson JA. Best practices and pragmatic approaches for patient-reported outcomes and quality of life measures in cancer clinical trials. J Natl Cancer Inst Monogr. 2025 Mar 1;2025(68):14-21. doi: 10.1093/jncimonographs/lgae047. PMID: 39989038; PMCID: PMC11848031. Read more

Please note the following upcoming meetings and abstract submission deadlines

UPCOMING MEETINGS

American Association for Cancer Research (AACR); Apr 25-30, 2025; Chicago, IL

American Association for Thoracic Surgery (AATS); May 2-5, 2025; Seattle, WA

American Brachytherapy Society (ABS); Jun 18-21, 2025; Nashville, TN

American College of Radiology (ACR); May 3-7, 2025; Washington, DC

American Head & Neck Society (AHNS); May 14-15, 2025; New Orleans, LA

American Radium Society (ARS) Annual Meeting; Apr 3-6, 2025; Seattle, WA

American Surgical Association (ASA); Apr 24-26, 2025; San Diego, CA

American Society of Breast Surgeons (ASBrS); Apr 30-May 4, 2025; Las Vegas, NV

American Society of Colon and Rectal Surgeons (ASCRS); May 11-14, 2025; San Diego, CA

Canadian Association of Radiation Oncology (CARO); Sep 10-13, 2025; Calgary, AB

Miami Breast Cancer Conference; Mar 6-9, 2025; Miami, FL

Society for Clinical Trials (SCT); May 18-21, 2025; Vancouver, BC

Society for Gynecologic Oncology (SGO); Mar 14-17, 2025; Seattle, WA

Society of Surgical Oncology (SSO) Annual Meeting; Mar 27-29, 2025; Tampa, FL

St. Gallen Breast Cancer Conference; Mar 12-15, 2025; Vienna Austria

UPCOMING ABSTRACT SUBMISSION DEADLINES

AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; Sep 18-21, 2025; Baltimore, MD; Due to publications committee Jun 10, 2025; Submission deadline Jun 24, 2025, 1:00 pm ET

American Society of Clinical Oncology (ASCO); May 30-Jun 3, 2025; Chicago, IL; LBA Mar 5, 2025 (placeholder required)

American Society for Radiation Oncology (ASTRO); Sep 28-Oct 1, 2025; San Francisco, CA; LBA Jul 10, 2025, 11:59 pm PT

European Society for Medical Oncology (ESMO); Oct 17-21, 2025; Berlin, Germany; Due to publications committee Apr 25, 2025; Submission deadline May 13, 2025, 21:00 CET; LBA Sep 9, 2025, 21:00 CET (placeholder required)

ESMO Breast Cancer; May 14-16, 2025; Munich, Germany; LBA Apr 15, 2025, 21:00 CET (placeholder required)

ESMO Gastrointestinal Cancers; Jul 2-5, 2025; Barcelona, Spain; Due to publications committee Mar 25, 2025; Submission deadline Apr 8, 2025, 21:00 CET; LBA Jun 5, 2025, 21:00 CET (placeholder required)

ESMO Gynaecological Cancers; Jun 19-21, 2025; Vienna, Austria; Due to publications committee Mar 18, 2025; Submission deadline Apr 1, 2025, 21:00 CET

European Society for Radiotherapy and Oncology (ESTRO); May 2-6, 2025; Vienna, Austria; LBA Mar 19, 2025

International Gynecologic Cancer Society (IGCS); Nov 5-7, 2025; Cape Town, South Africa; Due to publications committee Apr 21, 2025; Submission deadline May 5, 2025, 23:59 SAST; LBA Sep 29, 2025 (placeholder required)

International Society for Quality-of-Life Research (ISOQOL); Oct 22-25, 2025; Milwaukee, WI; Due to publications committee Mar 25, 2025; Submission deadline Apr 7, 2025

Radiological Society of North America (RSNA); Nov 30-Dec 4, 2025; Chicago, IL; Due to publications committee Apr 23, 2025; Submission deadline May 7, 2025, Noon CT

Western Association of Gynecologic Oncologists (WAGO); Jun 18-21, 2025; Colorado Springs, CO; Due to publications committee Mar 5, 2025; Submission deadline Mar 19, 2025, 11:59 pm PT