November 14, 2022

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

WEEKLY HIGHLIGHT

NRG Oncology Winter Semiannual Meeting registration is now open!




 

Register Here

Registration is now open for the NRG Oncology Winter 2023 Meeting to be held both in Orlando and virtually, January 26-28, 2023.


Click here to register today!


(Registrations after January 3rd will incur a late registration fee)

ACTIVATIONS

GASTROINTESTINAL

A022104/NRG-GI010: The Janus Rectal Cancer Trial, NCI version date October 21, 2022, is open to new patient enrollment, effective November 9, 2022 (posted on CTSU).

 

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Actively Recruiting MALE Patients only. Read More

 

2. BREAST / GASTROINTESTINAL

NRG-BR003, NRG-BR007, NRG-GI004, NRG-GI005, and NRG-GI008: Memo - Scheduling Protocol Therapy for Non-medical Delays (posted to individual protocol pages on the CTSU website)

 

3. CANCER PREVENTION & CONTROL

NRG-CC005/FORTE: November edition of the FORTE newsletter (posted on CTSU)


4. GASTROINTESTINAL

NRG-GI008: Slides from the Protocol Overview Webinars held on November 1st and 3rd are now posted on CTSU.

 

5. GENITOURINARY

NRG-GU007: Attention sites with NRG-GU007 open, we are currently enrolling to Dose Level 3, the final dose level for the phase I portion of the trial. More than ever, we need your support in reaching Dose Level 3 target accrual goal to complete the dose finding component of this trial and allow us to progress to the randomized phase II component. Please help us meet this target! Protocol documents for this trial are available on CTSU and please share our NRG-GU007 patient brochure with any eligible patients. Questions regarding this trial can be directed to the study Project Manager, Erin Moye at moyee@nrgoncology.org 


6. GYNECOLOGIC

GOG-0210: Biospecimens, biomarker data, clinical data, and epidemiologic data are available for request. Please visit the NRG Oncology website for more information on this important study with the overall goal of improving the outcome and/or quality of life for patients with endometrial cancer.

 

GOG-0225: To provide the most accurate and reliable assessment possible, sites are asked to answer any outstanding queries and update the Overall Survival status and last contact date for all patients enrolled on GOG-0225 no later than Friday, December 2, 2022. This trial utilizes the SEDES EDC system for form entry. If site personnel need access to SEDES for this study, please contact support@nrgoncology.org. SEDES can be accessed via the GOG Web menu.


NRG-GY012 and NRG-GY023 – BLOOD PRESSURE CUFF SUPPLY IS VERY LIMITED - Please be advised that VWR has a very limited supply of blood pressure cuffs at present. Please check your supplies on site for any overlooked cuffs prior to ordering. Thank you for your cooperation.  

 

7. LUNG

REGISTER TODAY! Information Webinar for the NRG-LU006 Clinical Trial

NRG Oncology will be hosting an informational webinar regarding the NRG-LU006 clinical trial on Thursday, November 17, 2022, from 7-8 pm ET. This webinar is open to all who register. This webinar is specifically aimed to engage thoracic surgeons and will address surgical concerns, barriers to enrollment and answer protocol-specific questions.


The Phase III randomized NRG-LU006 study is currently active and enrolling patients with malignant pleural mesothelioma (MPM). The trial is designed to compare adjuvant hemithoracic intensity-modulated pleural radiation therapy (IMPRINT) combined with pleurectomy/decortication surgery and systemic therapy to surgery and systemic therapy alone. The goal of this study is to see if the addition of adjuvant hemithoracic IMPRINT can improve overall survival for patients with MPM.

 

The webinar will be led by Andreas Rimner, MD, the Director of Thoracic Radiation Oncology Research at Memorial Sloan Cancer Kettering Center and NRG-LU006 Principal Investigator. Presentations will be followed by a question and answer segment with the study team.

 

Register here: https://bit.ly/NRG-LU006-Webinar-Registration

 

8. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, NRG-CC005 and NRG/SWOG S1914. Space is limited so register now and reserve your seat. The next webinar training is scheduled for Wednesday, December 14, 2022 

DRUG SAFETY AND INVESTIGATOR’S BROCHURE (IB) UPDATES

Drug Safety and Investigator’s Brochure updates have been issued for the following studies:

DRUG NAME

PROTOCOL

WEBSITE FOR SAFETY UPDATES

INVESTIGATOR’S BROCHURE (IB)*

Atezolizumab

NRG-BR004

NRG-GI004/

SWOG-S1610

CTSU

CTSU


Copanlisib

NRG-GY029

NRG


Olaparib

NSABP B-55

CTSU

X

*The current version of the Investigator Brochure Documents for Division of Cancer Treatment and Diagnosis (DCTD), National Cancer Institute (NCI)-sponsored trials are available for access via the Cancer Therapy Evaluation Program (CTEP) Online Agent Order Processing (OAOP) website. Log-in using your Identity and Access Management (IAM) username and password credentials and provide the requested information to access the document.

 

Every site principal investigator is responsible for reviewing this document. The Investigator Brochure is for use by the site principal investigator and any study personnel under his/her supervision who need to know the contents for the conduct of a clinical trial, including Institutional Review Board(s) or Independent Ethics Committee(s).

Thanksgiving Holiday Closure Information

Please see the memoranda posted on the CTSU website for Thanksgiving holiday closure information for the NRG Oncology Operations Offices, Statistics and Data Management Centers (SDMCs), Biospecimen Banks, Serum Bank, and McKesson's Clinical Research Services.



NRG Oncology Patient Advocate Committee: Call for Candidates

Help improve cancer clinical trials and the lives of cancer patients by becoming a patient advocate. We are currently recruiting volunteers for the Patient Advocate Committee’s membership with assignments to the following committees: Gastrointestinal Colorectal Cancer, Gastrointestinal Non-Colorectal Cancer, and Gynecologic Cancer. More information about the NRG Patient Advocate role, requirements, and benefits is available on the NRG Website.




What Do You Need to Know About the NRG-GU011 “NRG PROMETHEAN” Clinical Trial?

We interviewed Dr. Bridget Koontz, Principal Investigator for the NRG-GU011 “NRG PROMETHEAN” trial. The video is now posted to our YouTube channel. Learn more below.


NRG-GU011: A Phase II Double-Blinded, Placebo Controlled Trial of Prostate Oligometastatic Radiotherapy with or without Androgen Deprivation Therapy in Oligometastatic Prostate Cancer https://youtu.be/eKUmiRrGS18

 

Please remember: Any manuscripts resulting from the federally funded work of NRG Oncology are required to be submitted to the NRG Publications Department or to one of the individual staff members of the Publications Department before being submitted to the journal you have selected for publication. This is to ensure that policies of the NRG Publications Guidelines are met, that all approvals needed are dealt with in an efficient manner, and that submission through the NIHMS publications system, required for grant approvals, goes smoothly.

PUBLICATIONS REMINDERS

NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

 

Please note the following upcoming meeting and abstract submission deadline dates


UPCOMING MEETINGS

Radiological Society of North America (RSNA); Nov 27-Dec 1, 2022; Chicago, IL


San Antonio Breast Cancer Symposium (SABCS); Dec 6-10, 2022; San Antonio, TX


Society for Neuro-Oncology (SNO); Nov 16-20, 2022; Tampa, FL


Society of Urologic Oncology (SUO); Nov 30-Dec 2, 2022; San Diego, CA

 

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Association for Cancer Research (AACR); Apr 14-19, 2023; Orlando, FL; meeting submission deadline Nov 17, 2022, 11:59 ET; LBA Jan 12, 2023


American Head & Neck Society (AHNS); July 8-12, 2023; Montreal, QC Canada; due to publications committee Nov 14, 2022; meeting submission deadline Dec 2, 2022, 5 pm EST


American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium; Jan 19-21, 2023; San Francisco, CA; LBA Nov 15, 2022, NOON (EST)


American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium; Feb 16-18, 2023; San Francisco, CA; LBA Dec 13, 2022, NOON (EST)


ESMO Gynaecological Cancers Annual Congress 2023; Feb 23-24, 2023; Barcelona, Spain; due to publications committee Nov 15, 2022; meeting submission deadline Nov 29, 2022, TIP 9 pm CET (CntEurTime)


European Society for Radiotherapy and Oncology (ESTRO); May 12-16, 2023; Vienna, Austria; LBA Jan 18, 2023, 9:00 pm


Society for Clinical Trials (SCT); May 21-24, 2023; Baltimore, MD; Contributed Oral & Poster Presentations meeting submission deadline Nov 14, 2022


Society of Surgical Oncology (SSO 2023); Surgical Cancer Care; Mar 22-25, 2023; Boston, MA; LBA Dec 9, 2022


St. Gallen Breast Cancer Conference (SG-BCC); Mar 15-18, 2023; Vienna, Austria; due to publications committee Dec 2, 2022; meeting submission deadline Dec 16, 2022

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