November 24, 2025

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

NRG Oncology Website Update

The NRG Oncology website, www.nrgoncology.org, was recently updated to a new platform. While most changes will have minimal impact for our members, please note that during this process we reorganized and cleaned up some areas of our navigation. If you have questions regarding the website, please contact Communications@nrgoncology.org. 

Registration is OPEN for #NRG2026!

Registration is OPEN for the NRG 2026 Winter Meeting

Join us in San Francisco, CA for the NRG 2026 Winter Meeting. The meeting will be held in-person, January 22-24, 2026, with select virtual sessions being held January 12-16, and January 20, 2026. Register soon to avoid the late registration fee!

More information | Agenda | Register

Winter 2026 Symposium – Theranostics: Precision Imaging Meets Targeted Therapy

Join us on in San Francisco, CA on Thursday, January 22, 2026 from 8am-12pm PT. The session will also be available virtually. This symposium will provide a comprehensive look at theranostics and radiopharmaceutical therapy. The program will begin with an introduction to the scientific foundations of radiopharmaceuticals, outlining how these agents differ from external beam radiation, and the practical considerations of imaging, dosimetry, and safe delivery. Participants will gain insight into the operational, regulatory, and infrastructural requirements needed to build a successful theranostics program within their institution.

Program Chair: Denise Fabian, MD and Co-Chairs: Charles Kunos, MD/PhD; Elise Kohn, MD

More information | Register

Announcing the #NRG2026 Investigator & Career Development Committee Educational Session!

This year’s program explores protocol development from every angle—early-career investigators shaping their first studies, experienced leaders refining best practices, NRG operations guiding feasibility, experts addressing health care access, and insights from a disease site committee leader. Additional information is included in the session flyer.

NRG Scientific Session - Friday, January 23; 3-4:30pm PT

Join us for the #NRG2026 Scientific Session featuring updates on antibody–drug conjugates and novel approaches in breast and ovarian cancer, followed by highlights from top recent NRG abstracts presented at national meetings. Details are included in the session flyer.

NCORP Bootcamp at #NRG2026

Join NRG Oncology NCORP leaders for the NCORP 2026 Bootcamp designed to increase understanding of the NRG Oncology NCORP Research Base and NCORP Community Sites:

• Dr. Lisa Kachnic will provide an overview of the functions and strategic role of an NCORP Research Base.
• Dr. Carolyn Muller, PI of the University of New Mexico NCORP, will share insights from the field describing the operations and impact of an NCORP community site.

A panel discussion will focus on developing and enrolling to NCORP trials, with perspectives from both.

All attendees are invited to participate in interactive breakout groups focused on:

• Patient advocate engagement - To help investigators strengthen their NCORP concepts by integrating patient advocate perspectives early in development ensuring trials are understandable, feasible, and meaningful to participants.
• CPC, HCA and PCOR committees – learn more about NCORP concept development, collaboration with NRG committees, and integration of health care access throughout NRG trial development.
• Developing a framework for Advanced Practice Providers within NRG Oncology.

The #NRG2026 Bootcamp is being held on Thursday, January 22, 2026. Additional information is included on the posted session flyer.

Reminder, the following clinical trials are open to enrollment. Please continue to review your patient population and discuss enrollment opportunities with your clinical teams. All protocol related documents are posted on CTSU.

NRG-HN010: The HER2-low expressing cohort reopened to accrual on November 2, 2025. The HER2-positive cohort remains open and actively recruiting patients with salivary gland cancer.

AMENDMENT

CANCER PREVENTION & CONTROL

NRG-CC013: Amendment 2, version date September 16, 2025 (posted on CTSU)

FORM UPDATES

CANCER PREVETION & CONTROL

NRG-CC013: New Mucositis Assessment Form, November 14, 2025

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only (posted on CTSU)

2. BIOSPECIMEN BANK

Update: Kit Shipments to Sites in Canada

The shipment of kits to sites in Canada has resumed. Sites no longer need to provide their FedEx account number when ordering kits, unless they request to have a kit shipped overnight. Please contact the NRG Biospecimen Bank in Columbus if you have any questions:

• Phone: 614-722-2865
• Email: BPCBank@nationwidechildrens.org

NRG Oncology Biospecimen Bank - Columbus Phone Number

The NRG Oncology Biospecimen Bank - Columbus is phasing out its 866 number. The number is still listed in some older protocols, but when contacting the Bank in Columbus, please use 614-722-2865. The 866 number will be deactivated at the end of November 2025.

Printing Biospecimen Transmittal PDFs from Rave

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

3. BRAIN

NRG-BN011: The central lab, NYU Langone, will be closed on Thursday November 27, 2025, for Thanksgiving. Please plan tissue shipments accordingly. 

4. BREAST

NSABP B-55/BIG 6-13/OlympiA: Save the Date: Virtual Investigator Meeting (December 2, 2025; 12pm EST); and Investigator Letter re: Patient Retention (posted on CTSU)



5. CANCER PREVENTION & CONTROL

NRG-CC005/FORTE: Clinical research professionals can sign up for NRG Oncology Weekly Broadcasts to receive monthly FORTE Fridays updates directly to your inbox (click here).

NRG-CC008: November 2025 newsletter is available on CTSU.

6. GASTROINTESTINAL

NRG-GI011: The following documents are available on CTSU:

• Study Memorandum dated November 14, 2025, regarding a clarification on prior radiation treatment
• Updated Training Slides, version date November 17, 2025

NRG-GI012: Attn sites in Canada – NRG GI012 has been approved by Health Canada. The NOL and forms are posted to CTSU. Please submit the completed protocol signature page and Protocol training (RA and PI/QI) via the CTSU regulatory portal.

7. GENITOURINARY

RTOG-0926: A summary of research results is available on the NRG Patient Study Web Page. Sites, please share the summary of research results with study participants.

NRG-GU011: Please see Study Memorandum dated November 17, 2025 (posted on CTSU), regarding shipment timelines during the holidays. To avoid delays, submit shipment requests as soon as possible to support subject visits scheduled between November 10, 2025, and January 10, 2026.

8. GYNECOLOGIC

NRG-GY020: Approaching its final analysis. To provide the investigators with the most accurate information, please submit all overdue data and update any outstanding patient data queries by December 1, 2025.

NRG-GY026: Accruing patients of all stages and all histologic subtypes of endometrial cancer.

NRG-GY031: Please note there is an error in the section 4.2 table and the Biospecimen Collection and Submission Manual. The Part I PK collection is to be done on Cycle 1, Day 1, and Cycle 1, Day 8. This will be updated with the next amendment.

NRG-GY037 requires blocks to be submitted, but the study team recognizes variations in site operating procedures to release blocks. Please refer to the Letter to Pathologists in the Biospecimen Collection and Submission Manual. If your site is experiencing any issues with this requirement, please contact the study team as we can work with sites on a case-by-case basis to ensure patients have an opportunity to participate in this trial.

9. HEAD & NECK

RTOG 1216: The central lab, Ferris Laboratory, will not be accepting samples (fresh heparin and Streck blood tubes) on November 27, November 28, and December 1, due to the Thanksgiving holiday.

Please plan your appointments accordingly to avoid any delays or compromised samples.

NRG-HN008 - Reminder: please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important. 

10. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on NRG-BN014, NRG-BR009, NRG-CC005, NRG-CC011, NRG-CC013, NRG-CC014, NRG-CC015, NRG-GI011, NRG-GI012, NRG-GU015, and NRG-HN014. Space is limited so register now and reserve your seat. The next webinar training is scheduled for December 10, 2025.

1. Reminder - Thanksgiving Day Holiday Closure Information

Please see the memoranda posted on the CTSU website for Thanksgiving holiday closure information for the NRG Oncology Operations Offices, Statistics and Data Management Centers (SDMCs), Biospecimen Banks, and McKesson's Clinical Research Services.

2. NRG Oncology System Updates – Completed

NRG Oncology system updates occurred over the weekend and have now been completed. Please direct any questions to support@nrgoncology.org. 

4. GYN Cancer Committee Requesting Proposals

The NRG Gynecologic Cancer Committee is requesting proposals for clinical trials in advance of the Winter Semiannual Meeting. Submit completed proposals by December 19, 2025. Read more

5. NRG Oncology CLASS Modules

It’s here! NRG Oncology Protocol Support Committee’s first two interactive e-learning modules, Adverse Event Reporting and Quality Assurance Audits, are now live on CLASS. Dive in, test your knowledge, and get ready to learn! Catalog | CLASS (Compliance, Learning, and SOP Solutions). Instructions for using CLASS can be found on the NRG website.

6. PRESS RELEASE: NRG Oncology Adds New Leadership Members to Developmental Therapeutics, Patient Centered Outcomes Research, Protocol Operations Management, Head and Neck Cancer, and Translational Science Committees

NRG Oncology (NRG), a National Cancer Institute (NCI) National Clinical Trials Network (NCTN) group focused on improving outcomes for adults with cancer through multi-center clinical research, recently announced changes in leadership across multiple committees. Read the release 

8. NRG Member Information Form

We are excited to introduce the NRG Member Information Data Collection Initiative that will allow us to create a comprehensive member database, enabling us to better understand and serve our members. Your information will be kept secure and confidential, ensuring that your privacy is always protected. All members are encouraged to complete the form or indicate that they wish to opt out of this data collection initiative. 

Scan the QR code below or click this link to access the form. 

Questions? Read more here

PUBLICATIONS REMINDERS

Publications Policy & Guidelines

Please review the NRG Oncology NRG Oncology Publication policy and Guidelines for guidance on publication requirements.

Author Contact Information

All Authors are advised to keep their contact information up to date either via the NCI Clinical Trials Support Unit (CTSU) portal (https://ctsu.cancer.gov/) or by notifying NRG-Publications@NRGOncology.org directly.

NRG Oncology is pleased to report the scientific articles that appeared during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

PUBLISHED ARTICLES

Lukka HR, Pugh SL, Shipley WU, Major PP, Sartor O, Dayes IS, Bahary JP, Efstathiou JA, Pisansky TM, Zeitzer KL, Lawton CAF, Dess RT, Camarata AS, Balogh AG, Souhami L, Rosenthal SA, Pennington JD, Seiferheld WF, Feng FY, Sandler HM. Long-Term Results of NRG/RTOG 9601, a Randomized Trial of Radiation With or Without Antiandrogens in Patients Receiving Salvage Prostate Bed Radiation Therapy Postprostatectomy. Int J Radiat Oncol Biol Phys. 2025 Nov 15;123(4):990-999. doi: 10.1016/j.ijrobp.2025.07.1416. Epub 2025 Aug 5. PMID: 40752653. Read more.

Please note the following upcoming meetings and abstract submission deadlines

UPCOMING MEETINGS

American Radium Society (ARS) Annual Meeting; Apr 30-May 3, 2026; Newport Beach, CA

American Society of Clinical Oncology (ASCO) GI; Jan 8-10, 2026; San Francisco, CA

American Society of Clinical Oncology (ASCO) GU; Feb 26-28, 2026; San Francisco, CA

Radiological Society of North America (RSNA); Nov 30-Dec 4, 2025; Chicago, IL



San Antonio Breast Cancer Symposium (SABCS); Dec 9-12, 2025; San Antonio, TX

Society of Surgical Oncology (SSO) – Advanced Cancer Therapies; Feb 14-16, 2026; Fort Lauderdale, FL

Society of Urologic Oncology (SUO); Dec 2-5, 2025; Dallas, TX

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Association for Cancer Research (AACR); Apr 17-22, 2026; San Diego, CA; LBA and Clinical Trials Jan 6, 2026, 11:59 pm ET

American Head & Neck Society (AHNS) Annual Meeting; Jul 18-22, 2026; Boston, MA; Submission deadline Dec 5, 2025, 5:00 pm ET

American Society of Breast Surgeons (ASBrS); Apr 29-May 3, 2026; Seattle, WA; LBA Jan 9, 2026, 12:00 am PT

American Society of Clinical Oncology (ASCO); May 29-Jun 2, 2026; Chicago, IL; Due to publications committee Jan 13, 2026; Submission deadline Jan 27, 2026, 11:59 pm ET; LBA Mar 9, 2026, 12:00 pm ET (placeholder required)

American Society of Colon and Rectal Surgeons (ASCRS); May 9-12, 2026; Tampa, FL; LBA and Clinical Trials Jan 28, 2026

European Society of Gynaecological Oncology (ESGO); Feb 26-Mar 1, 2026; Copenhagen, Denmark; LBA Jan 15, 2026

American Society for Radiation Oncology (ASTRO); Boston, MA; Sep 27-30, 2026; Due to publications committee Feb 10, 2026; Submission deadline Feb 24, 2026; LBA Apr 20, 2026 (placeholder required)

ESMO (European Society for Medical Oncology) Breast; May 6-8, 2026; Berlin, Germany; Due to publications committee Jan 13, 2026; Submission deadline Jan 27, 2026, 21:00 CST; LBA Mar 31, 2026, 21:00 CST (placeholder required)

European Society for Radiotherapy and Oncology (ESTRO); May 15-19, 2026; Stockholm, Sweden; LBA Apr 8, 2026

Miami Breast Cancer Conference; Mar 5-8, 2026; Miami, FL; Due to publications committee Dec 22, 2025; Submission deadline Jan 5, 2026, 5:00 pm ET

Society of Surgical Oncology (SSO) – Annual Meeting; Mar 5-7; Phoenix, AZ; LBA Dec 1, 2025, 11:59 pm CT