September 23, 2024

NRG Oncology Broadcast archives are accessible from our website at any time. Please bookmark this link for your convenience.

The Journal of Clinical Oncology has published ‘Correlative Science in the Cooperative Group System—Re-Engineering for Success,’ which proposes public-private partnerships to increase resources and process innovations to open access to tissue banks. Read more.

CLOSURE

LUNG

S1914: Memorandum: Permanent Closure and Investigator and Participant Letters, dated September 6, 2024 (posted on CTSU)

TERMINATIONS

GYNECOLOGIC

GOG-0259: Terminated on July 27, 2024; version date: September 1, 2009 (memo posted on NRG Oncology)

GOG-0267: Terminated on July 27, 2024; version date: May 20, 2011 (memo posted on NRG Oncology)

AMENDMENT

GYNECOLOGIC

The following protocol amendment is in response to an NCI action letter for CTEP-supported studies involving palbociclib:

EAY191-N5: Amendment 2; version date: August 22, 2024 (posted on CTSU)

OTHER PROTOCOL NOTICES

1. ALL DISEASE SITES

NRG-GY022: Reminder: Actively Recruiting MALE Patients only Read More

2. BIOSPECIMEN BANKS

Printing Biospecimen Transmittal PDFs from Rave

Please note an effort is underway to clarify how to obtain a Biospecimen Transmittal PDF for submission to the NRG Oncology Biospecimen Bank. Read More

Shipping samples in extreme weather conditions

The NRG Oncology Biospecimen Bank staff would like to remind you to keep in mind weather conditions when shipping samples. 

• Be sure to add sufficient dry ice to frozen shipments. In extreme temperatures, if possible, store the samples in -80° C until the temperature comes down.
• Frozen biospecimens should be shipped to the bank on Monday through Wednesday for Tuesday through Thursday delivery.
• Do not ship any biospecimens the day before a holiday. Watch the NRG Weekly Broadcasts for holiday closure notices and instructions.
• Be aware of the weather conditions in your area and where the biospecimens will be shipped.
• In temperatures over 80° F, use a cool pack when shipping FFPE blocks.
• Always refer to the protocol or manual (Biospecimen Collection and Submission Manual or Pathology and Correlatives Manual) for shipping instruction.  

3. BRAIN

NRG-BN013: Patient Study Web Page is available on the NRG website and a Participant Brochure is available on the CTSU website (CIRB Approved Documents>Participant Brochure>Support Documents #1).

NRG-BN011: Sites in Canada – Updated NOL is posted on CTSU.

4. CANCER PREVENTION & CONTROL

NRG-CC010: The study is open to NRG sites in Japan and South Korea. The optional biospecimen collection does not apply to sites participating in these countries.

5. GASTROINTESTINAL

NRG-GI008/CIRCULATE-NORTH AMERICA: Memorandum, dated September 23, 2024, and Natera webinar slides (posted on CTSU).

6. GENITOURINARY

NRG-GU010: Updated Drug Destruction/Transfer Form posted on CTSU.

7. GYNECOLOGIC

NRG-GY026: Please note, the post-chemo cfDNA Whole Blood (WB03) should only be collected if the Pre-Treatment cfDNA Whole Blood (WB01) was collected.

NRG-GY028: ETCTN has approved the submission of unstained slides when a block absolutely cannot be submitted. This will be included in the next protocol amendment. Until such time, details regarding this alternate submission can be found here.

NRG-GY031: Please note, there is an error in the section 4.2 table and the Biospecimen Collection and Submission Manual. The Part I PK collection is to be done on Cycle 1, Day 1, and Cycle 1, Day 8. This will be updated with the next amendment.

8. HEAD & NECK

NRG-HN008

Reminder: please update treatment and AE data weekly. This is a Phase I trial and timely data submission is very important.

9. LUNG

NRG-LU005: Updated Blank Rave Forms packet and Data Submission Table, dated September 13, 2024, are posted on CTSU. Data collection on the Additional Lab Result Form is no longer required; this form has been removed from Rave. Baseline Lab Results, Lab Results, and Lab Results (Follow-up) forms have been updated.

10. VTOC TRAINING

The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on NRG-HN001, NRG-HN002, NRG-CC003, NRG-CC005, NRG-BR009, NRG-CC011, and NRG/SWOG S1914. Space is limited so register now and reserve your seat. The next webinar training is scheduled for October 9, 2024.

Drug Safety and Investigator’s Brochure updates have been issued for the following studies:

*The current version of the Investigator Brochure Documents for Division of Cancer Treatment and Diagnosis (DCTD), National Cancer Institute (NCI)-sponsored trials are available for access via the Cancer Therapy Evaluation Program (CTEP) Agent Inventory Management System (AURORA) application. Log-in using your Identity and Access Management (IAM) or ID.me credentials and provide the requested information to access the document.

Every site principal investigator is responsible for reviewing this document. The Investigator Brochure is for use by the site principal investigator and any study personnel under his/her supervision who need to know the contents for the conduct of a clinical trial, including Institutional Review Board(s) or Independent Ethics Committee(s).

1. Cancer Cooperative Group leaders propose a re-engineering of the nation’s correlative science program for cancer

The Journal of Clinical Oncology has published ‘Correlative Science in the Cooperative Group System—Re-Engineering for Success,’ which proposes public-private partnerships to increase resources and process innovations to open access to tissue banks. Read more.

2. Annual Call For NRG Oncology Committee Member Applications

Are you interested in serving on an NRG Oncology committee? NRG Oncology depends on its members to advance its mission. Our members help drive our research, develop protocols, contribute to our science, and so much more. If you are interested in serving on an NRG Oncology research committee, or if you are a member who had previously served on a committee and would like to re-engage please consider applying by following the instructions in the 2024 NRG ONCOLOGY GENERAL AND CORE COMMITTEES APPLICATION FORM and submitting a complete application.

All applications must be submitted by midnight ET October 9, 2024. 

Included committees for this rotation are:

·       Disease Specific Scientific Committees

·       Non-Disease Site Scientific Committees

·       Scientific Core Committees

·       Early Phase Trial Oversight Committee

Current committee members do not need to reapply.



3. NRG Member Demographics Data Collection Initiative

We are excited to introduce the NRG Member Demographics Data Collection Initiative that will allow us to create a comprehensive member database, enabling us to better understand and serve our members. Your information will be kept secure and confidential, ensuring that your privacy is always protected. All members are encouraged to complete the form or indicate that they wish to opt out of this data collection initiative. 

Scan the QR code below or click this link to access the form. 

Questions? Read more here

4. NCORP Pilot Grant – Call for Letter of Intent (LOI)

NRG NCORP is soliciting LOIs in preparation for the next NCORP pilot grant RFA.

• Researchers interested in applying must submit a Letter of Intent (LOI) by October 11, 2024. Click here to download the form
• The request for funding application (RFA) for NCORP pilot projects will be released in Spring 2025; however, interested applicants must submit a LOI.
• NCORP committee chairs will review LOIs and select those best aligned with committee goals, NCORP priorities and feasible.
• Selected investigators will be notified and invited to attend a workshop the NRG Winter Meeting in Phoenix, Arizona; January 16-18, 2025.

 Informational slides are available here.

NRG Oncology is pleased to report the scientific articles that appeared during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.

PUBLISHED ARTICLES

O'Dwyer PJ, Wolmark N, Hawkins DS, Schnall M, Dancey J, Blanke C, Mannel R, Galanis E, Le QT. Correlative Science in the Cooperative Group System-Re-Engineering for Success. J Clin Oncol. 2024 Sep 17:JCO2400527. doi: 10.1200/JCO.24.00527. Epub ahead of print. PMID: 39288338. Read more.

Please note the following upcoming meetings and abstract submission deadlines

UPCOMING MEETINGS

American Society for Radiation Oncology (ASTRO); Sep 29-Oct 2, 2024; Washington, DC

International Gynecologic Cancer Society (IGCS); Oct 16-18, 2024; Dublin, Ireland

International Society for Quality-of-Life Research (ISOQOL); Oct 13-16, 2024; Cologne, Germany

PA Breast Cancer Coalition (PBCC); Oct 15, 2024; Harrisburg, PA

Radiological Society of North America (RSNA); Dec 1-5, 2024; Chicago, IL

Society for Immunotherapy of Cancer (SITC); Nov 6-10, 2024; Houston, TX

Society for Neuro-Oncology (SNO); Nov 21-24, 2024; Houston, TX

UPCOMING ABSTRACT SUBMISSION DEADLINES

American Association for Cancer Research (AACR); April 25-30, 2025; Chicago, IL; due to publications committee Nov 12, 2024; submission deadline Nov 26, 2024

American Association for Thoracic Surgery (AATS); May 2-5, 2025; Seattle, WA; due to publications committee Oct 7, 2024; submission deadline Oct 14, 2024, 11:59 pm ET

American Head & Neck Society (AHNS); May 14-15, 2025; New Orleans, LA; due to publications committee Oct 18, 2024; submission deadline Nov 1, 2024, 5:00 pm ET

American Society of Breast Surgeons (ASBrS); Apr 30-May 4, 2025; Las Vegas, NV; due to publications committee Oct 23, 2024; submission deadline Nov 6, 2024, 3:00 am ET; LBA Feb 5, 2025 (placeholder required)

American Society of Clinical Oncology (ASCO); May 30-Jun 3, 2025; Chicago, IL; due to publications committee Jan 14, 2025; submission deadline Jan 28, 2025; LBA Mar 5, 2025 (placeholder required)

American Society of Clinical Oncology (ASCO) GI; Jan 23-25, 2025; San Francisco, CA; submission deadline Sep 24, 2024; LBA Oct 24, 2024 (placeholder required)

American Society of Clinical Oncology (ASCO) GU; Feb 13-15, 2025; San Francisco, CA; due to publications committee Oct 11, 2024; submission deadline Oct 15, 2024; LBA Nov 14, 2024 (placeholder required)

American Society of Colon and Rectal Surgeons (ASCRS); May 11-14, 2025; due to publications committee Oct 11, 2025; submission deadline Oct 15, 2025, 11:59 pm ET; LBA Jan 29, 2025, 11:59 pm ET

EORTC-NCI-AACR Symposium on Molecular Targets and therapies; Oct 23-25, 2024; Barcelona, Spain; LBA Sep 26, 2024

European Society of Gynaecological Oncology (ESGO); Feb 20-23, 2025; Rome, Italy; due to publications committee Oct 14, 2024; submission deadline Oct 28, 2024; LBA Jan 15, 2025 (placeholder required)

European Society for Radiotherapy and Oncology (ESTRO); May 2-6, 2025; Vienna, Austria; due to publications committee Nov 6, 2024; submission deadline Nov 20, 2024; LBA Mar 19, 2025

San Antonio Breast Cancer Society (SABCS); Dec 10-14, 2024; San Antonio, TX; LBA Sep 30, 2024, 11:59 pm CT

Society for Clinical Trials (SCT); May 18-21, 2025; Vancouver, BC; due to publications committee Nov 8, 2024; submission deadline Nov 22, 2024, 11:59 pm ET

Society for Gynecologic Oncology (SGO); Mar 14-17, 2025; Seattle, WA; submission deadline Sep 27, 2024

Society of Surgical Oncology (SSO) Annual Meeting; Mar 27-29, 2025; Tampa, FL; due to publications committee Sep 23, 2024; submission deadline Oct 7, 2024, 11:59 pm CT

SSO – Advanced Cancer Therapies; Feb 14-17, 2025; Scottsdale, AZ; due to publications committee Oct 2, 2024; submission deadline Oct 16, 2024



Society for Urologic Oncology (SUO); Dec 4-6, 2024; Dallas, TX; LBA Oct 1, 2024