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Neurturin plays a crucial role in the survival and maintenance of sympathetic neurons, and is also implicated in the development and regulation of the central nervous system (CNS). In addition, NTN is involved in regulating non-neuronal cell populations, such as haemopoietic cells, and genetic defects in NTN are linked to Hirschsprung disease (HSCR), a congenital disorder of neural crest development that results in intestinal obstruction.
Biosensis' Neurturin (NTN) antibodies are developed for advanced research on neurotrophic factors. These antibodies have undergone extensive validation for use in immunohistochemistry (IHC), Western blotting (WB), and dot blot techniques. They demonstrate exceptional specificity for neurturin and show no cross-reactivity with glial cell line-derived neurotrophic factor (GDNF). Additionally, these antibodies are reactive across human, mouse, and rat species, and are supplied as lyophilized whole serum, accompanied by detailed instructions for reconstitution and storage to ensure optimal stability. They are ideal for investigating the physiological and pathological roles of NTN in neural development and related disorders.
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