Dear customers, collaborators, partners & friends,

We hope this email finds you well. BioTools has been incredibly busy as demand for characterization of antibodies, mRNA and anti-virals (which are mostly chiral) has increased.

As summer comes to a close we would like to share our new partnerships, lots of great VOA papers, upcoming conferences and product updates. We thank you for your continued support.

Best wishes,
from everyone at BioTools, Inc.
BioTools Partners With Liverpool ChiroChem
BioTools and Liverpool ChiroChem announce a collaboration aimed at accelerating the discovery of novel, stereo-defined, enantioenriched compounds.
Florida, USA – [June 2021] – BioTools, provider of instrumentation and analytical services for structure elucidation of biologics and chiral molecules for drug discovery, and Liverpool ChiroChem (LCC), a chemical technology innovator that produces thousands of novel, multifunctional 3D fragments/scaffolds/building blocks to support new chiral entities (NCE)
discovery & development, announce a collaboration to determine the absolute configuration of LCC’s proprietary chirally-pure compounds. (READ MORE)
Papers of the Season
We love the publications - by our customers, collaborators and our own scientists! This month we feature three papers and a review.
For a full list of papers (from 1/2021 to 05/2021) click here
Absolute Configuration Reassignment of Natural Products: An Overview of the Last Decade
By Andrea N. L. Batista, Bianca R. P. Angrisani, Maria Emanuelle D. Lima, Stephanie M. P. da Silva, Vitória H. Schettini, Higor A. Chagas, Fernando M. dos Santos Jr., João M. Batista Jr. , and Alessandra L. Valverde
May 21, 2021, J. Braz. Chem. Soc.
V. Blair Journigan*, David Alarcón-Alarcón, Zhiwei Feng, Yuanqiang Wang, Tianjian Liang, Denise C. Dawley, A. R. M. Ruhul Amin, Camila Montano, Wade D. Van Horn, Xiang-Qun Xie, Antonio Ferrer-Montiel, and Asia Fernández-Carvajal
March 31, 2021, ACS Med. Chem. Lett.
 
Brian T. Chamberlain*, Mathilde Vincent, Jordan Nafie, Peter Müller, Anna Greka, and Florence F. Wagner*
February 22, 2021, The Journal of Organic Chemistry

FTIR Spectroscopy Detects Intermolecular β-Sheet Formation Above the High Temperature Tm for Two Monoclonal Antibodies
Garrett Baird, Chris Farrell, Jason Cheung, Andrew Semple, Jeffery Blue & Patrick L. Ahl
The Protein Journal 39, pages 318–327 (2020)
ProtaCal Gets An Update
ATR liquid and solid Protein databases are added!
Higher Order Structure (HOS) of biologics is one of many Critical Quality Attributes (CQA's) used in development of bio-therapeutics. FTIR in transmission is now well established in the field but in many cases measurements with the ATR accessory have advantages of simplicity and speed.

The specialized ATR protein databases will ensure the correctness and precision of secondary structure determination.
About ProtaCal
ProtaCal™ offers, for the first time, a unified approach to structure characterization of proteins! This new software allows scientists to determine structure from several spectroscopic techniques: FT-IR, RAMAN / ROA, CD (Circular Dichroism).
 
Same databases. Same algorithm. By using the same algorithm and databases containing the same proteins, an error is eliminated. So, now you can TRUST the results when comparing different techniques.
Upcoming Conferences
ICAVS-11 | Virtual Conference | Aug 23-26 | Click Here
Join us in August for ICAVS-11, International Conference on Advanced Vibrational Spectroscopy. We are proud to be a platinum sponsor at this virtual event. Learn about VCD, ROA and FTIR and all of our unique spectroscopic accessories.

BioTools will hold a online webinar
Tuesday, August 24th from
12:00 - 1:00pm (CEST)
in the Main Room
"Cutting Edge Spectroscopy for Characterization of Structure: Chirality and Biologics"
SCIX 2021 | In-Person Conference | Sept 26-Oct 1 | Rhode Island | Click Here
We hope you can join us for our first
in-person conference! In September will we be exhibiting at SCIX. We are very excited to be reunited with many of you
in Rhode Island.

Mon, Sept 27 | 3:50 PM – 5:30 PM    
ORAL SESSION: Structure Elucidation of Chiral and Biological Molecules
Chairs: Dr. Rina Dukor, Dr. Christian Johannessen

Thurs, Sept 30 | 8:30 AM – 10:10 AM     
Dr. Rina Dukor will present a talk
"Anti-Virals and Other Chiral Drugs: the Importance of VCD in Pharma R&D" to help celebrate and honor Prof. Bhavya Sharma's Spectroscopy's Emerging Leader in Molecular Spectroscopy Award.
BioTools, Inc. | Your Research Deserves the Best!