Medical abortion with mifepristone and misoprostol is increasingly used as an outpatient alternative to aspiration, but lack of evidence has limited the use of abortion pills beyond 10 weeks of pregnancy in many clinics and facilities. We sought to bridge the evidence gap about outpatient medical abortion in the later first trimester. Better information about how well a common medical abortion regimen works in the 11th week of pregnancy is beneficial for health providers and for people who prefer to avoid aspiration procedures. An effective medical abortion regimen through 11 weeks also increases access to safe abortion care where providers trained in aspiration are scarce.
We conducted two sequential studies to evaluate the success of medical abortion regimens in the 11th week of pregnancy.