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The Pam and Rolando Del Maestro Family Undergraduate Research Competition is an opportunity to showcase your work to other scientists, researchers, and professionals attending the Research Symposium. The top three (3) winning teams receive monetary prizes. Presentations will be relevant to the brain tumour research community.

This competition allows students to create a research proposal, practice presentation skills, and receive constructive feedback from a panel that includes physicians and researchers. This competition will enable students time to network and creates awareness while engaging the brain tumour community in brain tumour research.

Apply Now

DUNN with Cancer BRAIN TUMOUR RESEARCH FELLOWSHIP 2022-2023

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Muhammad Vaseem Shaikh

Postdoctoral Research Fellow at

McMaster University, Hamilton, ON

Project Entitled: “Allogeneic, “off-the-shelf” CD122 CAR-T immunotherapy for Glioblastoma.”

 

Project Summary:

Glioblastoma (GBM) is the most common malignant brain tumour. Despite an aggressive therapy regimen, almost all patients relapse 7-9 months post-diagnosis. Therapy failure and poor patient outcomes may be attributed to a small population of glioblastoma stem cells (GSCs) that escape therapy and seed disease recurrence.


GSCs are most notably identified by the cell surface protein CD133, which has previously been associated with pro-tumour properties, including treatment resistance, tumour growth, maintenance, progression and metastasis. Earlier in the Singh Lab, we developed an engineered T-cell therapy, known as a CAR-T, capable of recognizing CD133 to induce tumour cell death. While this showed success in our animal models of human GBM, other considerations must be addressed on its path to clinical development.


Currently, CAR-T therapies are generated from T-cells taken from cancer patients. This hosts a myriad of concerns, including the quality of patient T-cells, the time and cost to manufacture, and their availability for patients with rapidly progressing diseases. Hence, to circumvent this issue, we aim to develop and test the donor-derived CAR-T cells genetically engineered for safe usage in GBM patients as a readily available, “off-the-shelf” therapy.

Read More

CURRENT FUNDING OPPORTUNITIES

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Accepting Applications Now!


We are currently seeking outstanding researchers conducting research relevant to Pediatrics, GBM and Quality of Life. All such proposals will be given serious consideration that is brain tumour related.


Applications can be from multidisciplinary teams or individual investigators. Multidisciplinary collaborations are encouraged, yet the lead investigator must submit applications.


Applications for grants of up to $50,000 will be considered.


Please read the guidelines.

Apply Now
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Brain Tumour Research Grants

Accepting applications!

Thanks to donors, the Research Grant Program provides financial support to Canadian researchers with critical funds that help to propel their research forward into the future.



Innovative research proposals such as those that incorporate novel or original concepts that have the potential to make a difference are also considered.


Please read the guideline.

Apply Now

RESEARCH SNAPSHOT

Dr. Xian Wang

Postdoctoral Research Fellow at

Hospital for Sick Kids, Toronto


Project Title: Targeted mechanical ablation of Glioblastoma using spatiotemporally controlled magnetic carbon nanotubes


Watch his video presentation below.

Read More About Dr. Wang's Research
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Download Our New App!


Our resources are now available at your fingertips! Our new mobile app is free to download and is available on the Apple and Google Play stores.

Download the App here.

2022 BRAIN TUMOUR WALK

Register Now!

CURRENT FUNDING OPPORTUNITIES | BRAIN TUMOUR REGISTRY | BRAIN TUMOUR TISSUE BANK

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